But sir.. in the book Paediatric Endocrinology by MEENA P DESAI its mentioned that...The conversation of corticosterone to 18OH Corticosterone is mediated by 18 hydroxylase and conversion of 18 OH corticosterone to aldosterone is by 18 oxidase..
If your adrenal glands are fatigued, then caffeine can cause your adrenals to overwork to make more cortisol and burns out your glands. This leads to your adrenals being weakened and less able to respond adequately. This is why coffee has less and less effect over time on people with adrenal fatigue.12 Aug 2017
How about "Cortisone Acetate"? Where abouts in the chain would that come, and how is it synthesized? My body doesn't produce hydro-cortisone as I don't have a pituitary gland, so I take cortisone acetate orally. I'm curious to know how this is synthesized as well.
Well delivered, but Kaplan says, It's 21 (beta) hydroxylase which converts progesterone and 17-hydroxyprogesterone to 11-deoxycorticosterone and 11-deoxtcortisol, respectively. And FA mentioned, just (21-hydroxylase). Why did you mention 21 (alpha) hydroxylase? Reference?
21 (alpha) hydroxylase is mentioned in the book "Basic & clinical Pharmacology by Bertram G Katzung", 13th edition, Page 681 & 687. Many other books refer it simply as 21 hydroxylase.......But nowhere it is mentioned as 21 (beta) hydroxylase ......... Hope that clarifies ..........
21 (alpha) hydroxylase is mentioned in the book "Basic & clinical Pharmacology by Bertram G Katzung", 13th edition, Page 681 & 687. Many other books refer it simply as 21 hydroxylase.......But nowhere it is mentioned as 21 (beta) hydroxylase ......... Hope that clarifies ..........
![Thyroid Hormone Synthesis: Step-By-Step Pathway [Physiology Explained]](http://i.ytimg.com/vi/1Dgz9Pky6WA/mqdefault.jpg)
Easy, simple understandable teaching. Thank you🌹
This has finally clicked. Thank you sir!!! 🙏
I'm not a medical student, but independent researcher. This is very relevant to women with PMDD. PLease help.
But sir.. in the book Paediatric Endocrinology by MEENA P DESAI its mentioned that...The conversation of corticosterone to 18OH Corticosterone is mediated by 18 hydroxylase and conversion of 18 OH corticosterone to aldosterone is by 18 oxidase..
Hi Doc - great video - quick question does Cholestrol convert to pregnenolone inside the adrenals?
That was very good and easy to understand video, much appreciated man🤝
good explanation
u nailed it in just few minutes...thank you soooooooooooooo muchhhhhhhhhhhhhh dr shb
Amazingly explained! Thank you
You are very welcome .....
Excellent....sir. very easy to remember.
If your adrenal glands are fatigued, then caffeine can cause your adrenals to overwork to make more cortisol and burns out your glands. This leads to your adrenals being weakened and less able to respond adequately. This is why coffee has less and less effect over time on people with adrenal fatigue.12 Aug 2017
Thank you so much for these videos!
Excellent video
Thanks ......
you are a genius.
Wow ❤❤❤! It's just amazing
Thank you so much
great!!!
thanks alot
Thank you!!
Sir biosynthesis of steroids make videos please... Is this same ?
So helpful
U r great sir thanks a lot it was quite confusing.
Very informative and short... Thanks sir
How about "Cortisone Acetate"? Where abouts in the chain would that come, and how is it synthesized?
My body doesn't produce hydro-cortisone as I don't have a pituitary gland, so I take cortisone acetate orally.
I'm curious to know how this is synthesized as well.
Well xplained sir...it cleared all my doubts
Many thanks Yashwant ...... I am happy you found it beneficial .......
Awesome video Sir...Thanks much..!!🙂
You are welcome.......
Sir, what would be the rate limiting step of this pathway? will it be the conversion of cholesterol in pregnenolone?
Yes for sure
Thanks for this. Good for revision
Very helpful
excellent. thank you.
Thank you so much sir
Very helpful
Thank you sir ❤
Very good one, thankful
You are most welcome ......
Sir! I haven't found any video about Androgens and antiandrogens.Kindly guide me
Beautiful!
Very nicely explained
Thanks Pratikee......
Thank you!
You are welcome ......
Thanks sir
hi doc. i noticed that there was no conversion to the Androstenedione. how it will happen to be a testosterone and estradiol?
Nice.. Well explained
Thank you.....
Thank u so much sir this was helpful 🤎👍🏻
Well delivered, but Kaplan says, It's 21 (beta) hydroxylase which converts progesterone and 17-hydroxyprogesterone to 11-deoxycorticosterone and 11-deoxtcortisol, respectively. And FA mentioned, just (21-hydroxylase). Why did you mention 21 (alpha) hydroxylase? Reference?
21 (alpha) hydroxylase is mentioned in the book "Basic & clinical Pharmacology by Bertram G Katzung", 13th edition, Page 681 & 687. Many other books refer it simply as 21 hydroxylase.......But nowhere it is mentioned as 21 (beta) hydroxylase ......... Hope that clarifies ..........
i noticed this too
Is it 21 BETA hydroxylase ..??.... ?..
21 (alpha) hydroxylase is mentioned in the book "Basic & clinical Pharmacology by Bertram G Katzung", 13th edition, Page 681 & 687. Many other books refer it simply as 21 hydroxylase.......But nowhere it is mentioned as 21 (beta) hydroxylase ......... Hope that clarifies ..........
sir Hindi me bhi Sare Harmones Ka biosynthesis btao n sir...
GD ONE... can u pl explain further reg androstenedione ?
Sure, I will try to do so in one of my future videos......
Awesome
Amazing amazing, but I was watching this video the outcome testosterone, but here it wasn’t