you all probably dont care at all but does someone know a trick to get back into an Instagram account..? I somehow lost the password. I would appreciate any help you can offer me!
@Bryan Nova I really appreciate your reply. I got to the site on google and im trying it out now. Looks like it's gonna take quite some time so I will reply here later with my results.
Thank god!! Hurrah a new vedios... I really REALLY admire the way u teach... So CLEARLY, PRECISELY, INDEPTH CONCEPTS IN UNDERSTANDABLE WAY!!! This whole playlist is just PRICELESS GIFT THANK U FOR MAKING ME FALL IN LOVE WITH PHARM🙏🙏😂which I never felt it so for past 3 yrs... U are Awesome.. thank u for SHARING AND TEACHING US BY SPENDING UR VALUABLE TIME
For the MD ( maintenance dose ) , dont we neeed to take into account the time intervals in which the designated drug is given in order to calculate the dose rate ?
With respect to fluoxetine, it has a half-life of 5-7 days and is therefore eliminated between 25 - 35 days after the last dose. From this video it would take 25 - 35 days to reach steady-state concentration. If the patient then starts taking 20 mg/day, does it take another 25 - 35 days to reach the next steady-state concentration? If not, what is the way of calculating that? Also, there’s inflammation that after steady-state with fluoxetine, because of the long half-life, then dosing can occur every third day.
Thank you for the video. It was great! One small question though. When calculating volume of distribution, aren't we suppose to take the volume or weight of fluid which is 60% of total body weight 60% of 80 = 48 kg or 48 L than the body weight itself?
I think 60% of total body weight is total body water... Here they have already given Vd in the unit of L/kg so you just need the total body weight for calculating Vd
Winner of a video, I have been researching "preventative maintenance plan example" for a while now, and I think this has helped. Have you ever come across - Peanlivory Singular Predominance - (should be on google have a look ) ? It is a smashing one of a kind product for discovering how to learning how to start a successful handyman business without the normal expense. Ive heard some great things about it and my m8 got excellent results with it.
With fluoxetine that has a half-life of 5 days, why does the patient take it every day? It would seem the patient is given more drug than s/he can eliminate and the the plasma concentration will just continue increasing with each daily dose. What am I not understanding?
Is there even a video for ORAL dosage regimens (DIGOXIN) in particular; calculating steady state peaks and troughs and time to steady state. Using Ka (absorption RC) and K (elimination RC)? If not, someone please help me.
I understand that you want future doctors to know that 4 - 5 half-lives are required to reach steady-state, but I want to know why. Every video that I watch says the same thing without any explanation and it is extremely frustrating because I'd like to get the big picture rather than memorizing an arbitrary number.
I've understood all your previous videos very well and they were very helpful. But this video I just don't understand as well. Please bring back the previous teacher.
But where is lecture 14? I could not find it anywhere.
These videos are FANTASTIC. Wonderfully helpful for my doctorate level pharmacology material!! Thank you so much!
you all probably dont care at all but does someone know a trick to get back into an Instagram account..?
I somehow lost the password. I would appreciate any help you can offer me!
@Lachlan Shepherd Instablaster ;)
@Bryan Nova I really appreciate your reply. I got to the site on google and im trying it out now.
Looks like it's gonna take quite some time so I will reply here later with my results.
@Bryan Nova It did the trick and I now got access to my account again. I'm so happy:D
Thanks so much you saved my account!
@Lachlan Shepherd You are welcome =)
Thank god!! Hurrah a new vedios... I really REALLY admire the way u teach... So CLEARLY, PRECISELY, INDEPTH CONCEPTS IN UNDERSTANDABLE WAY!!!
This whole playlist is just PRICELESS GIFT
THANK U FOR MAKING ME FALL IN LOVE WITH PHARM🙏🙏😂which I never felt it so for past 3 yrs... U are Awesome.. thank u for SHARING AND TEACHING US BY SPENDING UR VALUABLE TIME
So happy you posted again ! You are a great teacher, please continue!
For the MD ( maintenance dose ) , dont we neeed to take into account the time intervals in which the designated drug is given in order to calculate the dose rate ?
This video was very helpful, thanks!
I’m lucky person as i found ur channel,
I subscribed 🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹🌹
Thank u doc ❤️❤️❤️❤️❤️
With respect to fluoxetine, it has a half-life of 5-7 days and is therefore eliminated between 25 - 35 days after the last dose. From this video it would take 25 - 35 days to reach steady-state concentration.
If the patient then starts taking 20 mg/day, does it take another 25 - 35 days to reach the next steady-state concentration? If not, what is the way of calculating that?
Also, there’s inflammation that after steady-state with fluoxetine, because of the long half-life, then dosing can occur every third day.
Thank you for the video. It was great! One small question though. When calculating volume of distribution, aren't we suppose to take the volume or weight of fluid which is 60% of total body weight 60% of 80 = 48 kg or 48 L than the body weight itself?
I think 60% of total body weight is total body water...
Here they have already given Vd in the unit of L/kg so you just need the total body weight for calculating Vd
Sir,can you please upload the lecture 14 on ion trapping..It's missing
Winner of a video, I have been researching "preventative maintenance plan example" for a while now, and I think this has helped. Have you ever come across - Peanlivory Singular Predominance - (should be on google have a look ) ? It is a smashing one of a kind product for discovering how to learning how to start a successful handyman business without the normal expense. Ive heard some great things about it and my m8 got excellent results with it.
With fluoxetine that has a half-life of 5 days, why does the patient take it every day? It would seem the patient is given more drug than s/he can eliminate and the the plasma concentration will just continue increasing with each daily dose. What am I not understanding?
Thanks for posting again!!!
Steady state should be 94% after 4 half lives and 97% after 5 half lives
Sir , Loading dose is always given as Iv ? Nd what about Maintenance dose,it will also be given as IV always or can be given as orally?
He said if IV is used we can use 1 as bioavailability, any route can be used but they have different bioavailability.
Sir make many more videos as you can
Is there even a video for ORAL dosage regimens (DIGOXIN) in particular; calculating steady state peaks and troughs and time to steady state. Using Ka (absorption RC) and K (elimination RC)? If not, someone please help me.
You can find it in Box 2-4, Box 2-5 and Box 2-6 of Chapter 2 of Goodman And Gilman’s 13th Edition 👍🏻
How come certain drugs can be loaded while others cannot
very helpful thank you so much ^-^
Good bless you
So nice 👍
Well done...!
Thanks for a new vidjayo
I understand that you want future doctors to know that 4 - 5 half-lives are required to reach steady-state, but I want to know why. Every video that I watch says the same thing without any explanation and it is extremely frustrating because I'd like to get the big picture rather than memorizing an arbitrary number.
nombla1111 yes yes and yes! I've been looking for a video like that I love learning conceptually
I've understood all your previous videos very well and they were very helpful. But this video I just don't understand as well. Please bring back the previous teacher.
lol is the same person
👏👏
4.32 half lives are required to achieve 95% ss