Hi everyone, I just bought a Breather Fit (not sponsored!) to train both the inspiratory and expiratory muscles. It will arrive by Thursday, and I'll continue to track FEV1 and BP at least 3x/week to see if lung function and BP improve.
Aren't you loosing track here? For example, grip strength is a great predictor of aging. But, does that mean that we should train for grip strength? Will training for grip strength help us to reduce our biological age? I don't think so. Grip strength is jus a proxy, and we should train whole body traditional sport training and perform healthy strengthening prone life style activities. The grip strength is a proxy of healthy lifestyle. Now, should we train for lung strength? I would say NO. But we should do the same described above, sport training and healthy lifestyle activities thant strengths body as a whole including lungs. I wonder how would you improve your marks with aerobic training (running, bike, rowing), swimming, yoga (they breath a lot). Probably there is one sport better than other. Probably swimmers have better lung/BP marks, probably runners, probably yogies. Do you know? Have you tried sports training to improve this?
Now that you've been using the Breather Fit for several months, have you observed any meaningful improvements in your FEV1, BP, and/or lung function? Would you recommend the Breather Fit device? There's also a less expensive inspiratory and expiratory muscle training device called Expand-A-Lung. Have you tried that one? Thank you!
Hey Robert, we're 1 video away from that story (3/5/23)! In hot-off-the-presses news, FEV1 got worse (I may have overtrained with it), whereas BP improved. Is that correlation, or causation? To answer that, we'll also see if those changes went away when I stopped using the Breather Fit. I haven't tried other models, but I am considering repeating the Breather Fit experiment, but training with it less often (not up to 8 min/d, but maybe half that amount).
@@conqueragingordietrying123 Thank you! Looking forward to your upcoming video. I hope you repeat the Breather Fit experiment and can find a training frequency/duration "sweet spot" which results in both improved FEV1 and BP.
It's not off base-the highest that I've gone for fat intake is ~120g/d, and that resulted in more biomarkers going in the wrong direction than right. However, some of that may be driven by dairy SFAs-I'm considering slowly raising my fat intake without cheese and full-fat yogurt to see if the results are repeatable. So hardcore keto no, but relatively higher fat ~44% yes.
Nebulised glutathione as well as NAC, Astragalus in some data shows beneficial effects for COPD patients. Some research also suggests NMN may also assist. what are your thoughts?
@@conqueragingordietrying123 I wonder if dusting off my trumpet would do me some good. I might scare the dogs though. haha I used to play aloooong time ago.. =)~
@@TGSamantha091 The trumpet or any device that provides resistance is a good idea! Ideally, tracking FEV1 (or other lung function measures) and BP to see if it works...
I'd love to see a comparison between using a device, and simply training with a very thin straw, or fingers mostly blocking the nostrils. It seems like it shouldn't be hard to create your own resistance while breathing, though with a device it's certainly easier to quantify it. You reminded me of Arnold Jacobs, who was possibly the most influential tuba player in history, and that was despite allegedly having 50% lung capacity due to childhood asthma and COPD. Breathing exercises were his specialty, and his teachings remain influential for all wind players. His self taught understanding of breathing physiology was apparently better than his doctors'. He died at 83, and I can't find his cause of death. Probably not relevant, but I felt like sharing! It would be interesting to see a longevity comparison between different types of musicians.
Definitely, that's a good idea. I haven't seen any studies comparing that yet, though. That's interesting about Arnold Jacobs, and I wonder if wind players live longer than average, especially considering that FEV1 may be a top predictor.
@@conqueragingordietrying123 I did a quick search, and while it doesn't seem like a great study "Lifespan and longevity among representatives of creative professions" which cites "Longevity and some reasons of death of musicians of the 20th century" says Conductors and harpists live the longest, which is probably a wealth/education factor more than anything else.
Several years ago I bought a cheap device online (maybe $3 or $5) that's basically a silicone mouthpiece attached to a simple rotating valve to adjust air resistance. Does the job, but does not allow for independent adjustment of inpiratory vs expiratory pressure.
@@conqueragingordietrying123 You're welcome. Thank you for the great content! Do you happen to have a formula that uses FEV1 or other pulmonary function markers that can be used to calculate chronological (pulmonary) age?
I love these devices, BUT i cannot discard pranayam and Qigong. As a practitioner of both i'm pretty sure that some techniques will improve this even better. Awesome topic by the way
Definitely-it's in "Spirometry Reference Equations for Central European Populations from School Age to Old Age", and that link is in the video's description.
One thing that improved my breathing a lot was speaking voice lessons. I took classes (Freeing the Natural Voice, Level 1 & 2) at The Linklater Center in NYC 5 years ago. The classes were based on Kristen Linklater's speaking voice method. Before the pandemic, the classes were in person. Now they offer classes online as well.
Thanks Ed. I'm leaning towards the Breather Fit, but I'm also considering Expand-A-Lung and Ultrabreathe. I want to start with an affordable trainer first, as each of those are < $60 USD.
@@conqueragingordietrying123 I bought powerbreathe about a year or so ago. I used it once and it is still sitting in the box today. I am not even sure where the box is at the moment.
@@jackbuaer3828 Hmmm, based on the data in the video, it's probably a good idea to use it! I'd track FEV1 and BP, too, so see if they correspondingly improve.
@@conqueragingordietrying123 Well, I do have a problem with BP. I was able to keep the top number 120s and 130s last year with many interventions going, sauna, racquet sports, walking, lifting, hibiscus, ice bath, citrulline beat juice. After I increased my racquet sports training, my BP recently went through the roof into the 150s despite having relatively low bodyfat and a low salt whole foods diet. I made the decision to go on Telmisartan / Amplodine combo to see if I could get it down in the short term. I do at least 90 minutes of exercise / sauna activity day spread out into 3 or 4 daily sessions. I have changed my 25 minute morning walk with the dog into a jog to see if that helps with cardio measurements. I might pull out the powerbreathe, but each thing I add to the regimen leads to the possibility of overtraining. I measure my overtraining as to how I feel. My body shuts downs if I do too much and I oversleep. Right now, I have decent energy with what I am doing. The powerbreathe may come out in the future. I have at least located the box.
IDIAG P100 is the best device out there as it adjusts and keeps CO2 steady as well as provide feedback and stats. However, they doubled their price and got so expensive as to price out regular users. Makes me sad.
Systolic blood pressure is raised due to hardening of the arteries and high blood pressure is a leading predictor of early death. Would be good to know what your techniques can do against this hardening.
I'd have to look to see what'd published in that area, but note that my usual focus is on maximizing health, rather than trying to fix aspects of aging.
when you choose your device to improve your lung function I would be ever so grateful if you could let me know as I am saying to purchase something effective for my mother to improve her lung function
SHBG stands at the second place, but using it as an aging marker is dangerous at least. SHBG also rises with a healthy fiber-rich diet, and low levels of SHBG are linked to several diseases.
@@conqueragingordietrying123 I've never used one, but I don't think it does. Pursed lip breathing exercises? I look forward to the devices you recommend. Thank you
I did see nutritional changes such as following an anti inflammatory diet, beetroot (or extract) and foods know to improve the microbiome can improve lung function along with sauna and specific breathing exercises such as Wim Hoff style sessions.
I’m a long time 10k runner. My average Bp is 100/60. All these years I think running has so far saved me from chronic diseases, previous bad eating habits etc. I used to teach asthmatics how to do peak flow. I wished I’ve jotted down the numbers I use to get way back then.
100/60 is great KoiRun. It could go either way with endurance athletes-anecdotally, I've seen that for every 1 that is in good health with good eating habits, there are many more with terrible eating habits.
It’s a bit low and sometimes I can tell. Michael, would you please talk about orthostatic hypotension? I think it’s a huge risk factor for the elderly in regards to falls. Mid sleep getting up micturition is a common occurrence that plays a role.
@@KoiRun50 Both values are very good, they're better than mine (average = 537 L/min). My understanding is that FEV1 is a better measure of lung function, but Peak flow can be used where FEV1 is not available.
I would say you don't need to buy an imst+emst as everyone has one built in. When we exercise more it is normal to switch from nose to mouth breathing. If you don't switch you are automatically getting built in resistance. You can even modify this with tape and breathing strips. As many noses are different you won't have the same range but as your study is n=1 it shouldn't matter.
Most physicians are already wary to blood test multiple times/yr, and I don't see any way that they'd let me get multiple MRIs/yr for eat blood test, even without the cost.
Perhaps it would be helpful just to get a baseline and then lower frequency for the MRI than for blood tests? Annual or every two years? Hopefully you still will get lots of data points :)
@@christopherbrand5360 Knowing the battles that I've had with GPs just for blood tests, I think it will be more difficult (unfortunately) to convince an MD to get regular MRIs, even 1x/2 years.
Ha, here! I've summarized most of the big picture biomarkers in videos. If not, my website, too. Everything else is reference-range based, which isn't based on what's optimal.
@@conqueragingordietrying123 o OK, I was looking for a summary guide. I'll check your website then thank you. But if you come across anything please do let me know. I subscribe so will see your notifications and really appreciate your advise. I have my mother's blood results now and want to look at setting some realistic goals to improve her health and overall longevity
Have you measured your Vo2Max? Do you believe your relatively low activity levels (which you do intentionally to ''preserve'' higher HRV) may come at the cost of a low Vo2Max, a low FEV1, and in the long-term, low HRV itself? Most of my athletes with high Vo2Maxes (estimated via running tests) have very high FEV1 for their age(measured by incentive spirometer). They also have low resting HR's, and high HRV's (according to various devices, including Whoop, Fitbits, Apple Watches, Garmins, and Oura Rings).
I've measured VO2max 3x since 2010, and it was in the 40-45 range. I haven't tested it in about 5 years, though. Based on my 2 eighty-minute workouts/week, I meet the Physical Activity Guidelines for Americans, and that doesn't include all the walking that I do otherwise-it's hard to say that my activity levels are low. In terms of titrating activity to optimize both RHR and HRV, will that limit VO2max? Probably, but I'd rather not be overtrained. The goal is fitness as a component of longevity, not fitness without longevity.
Great presentation as always, thanks! Libert et al.'s tables of top predictors of age are very interesting. I'm a little surprised that SHBG and testosterone separately are that high in the list for males because mutations in the SHBG gene (rs12150660 and rs1799941) can give you SHBG and testosterone levels that are off the charts and that are not indicative of age. I would have thought that *bioavailable* testosterone (or free testosterone) is more universally comparable, which takes both total testosterone and SHBG into account.
Love your channel. Have same Spiro device and similar issues, so I will be following your journey closely. Did any of the studies discuss through what mechanism improved FEV1 lowers BP?
I can imagine systolic BP and SHBG being on top of waiting list for BPB. I doubt the inclusion of insulin because low insulin can indicate low insulin resistance and advanced age at the same time--a mixed signal.
I recently bought an IMST device after having my whole genome decoded and finding out I have low Alpha-1 Antitrypsin levels which puts me at greater risk of COPD and Pneumonia. It would be interesting to see how you would combine knowledge of weaknesses in your personal genome in combination with biomarkers to extend lifespan as I feel you need both to really Conquer Aging.
Have you increased lung function with the IMST device? I have 23andme data, but I pay far less attention to the genomic data, as it indicates what may be possible, whereas circulating biomarkers are more indicative of active processes.
@@conqueragingordietrying123 I just started so don't have enough data yet but will be monitoring my blood pressure to see if it makes a difference, the nice thing about genomic data is that it can also tell you how well you will respond to different supplements or substances, whether you are hypersensitive or where they could be toxic or if you would respond well, using my full genome with the geneticgenie site has been a gold mine for me in this regard in addition to health risks, considering whole genome sequencing is now 300 dollars its well worth it IMHO.
Hi everyone, I just bought a Breather Fit (not sponsored!) to train both the inspiratory and expiratory muscles. It will arrive by Thursday, and I'll continue to track FEV1 and BP at least 3x/week to see if lung function and BP improve.
Look forward to hearing
If bp and lung function improve .
sex hormone binding globulin SHBG is number two predictor of chronological age. Any idea why?
SHBG is on my to-do list, so I don't have any idea why, for now...
Aren't you loosing track here?
For example, grip strength is a great predictor of aging. But, does that mean that we should train for grip strength? Will training for grip strength help us to reduce our biological age? I don't think so. Grip strength is jus a proxy, and we should train whole body traditional sport training and perform healthy strengthening prone life style activities. The grip strength is a proxy of healthy lifestyle.
Now, should we train for lung strength? I would say NO. But we should do the same described above, sport training and healthy lifestyle activities thant strengths body as a whole including lungs. I wonder how would you improve your marks with aerobic training (running, bike, rowing), swimming, yoga (they breath a lot). Probably there is one sport better than other. Probably swimmers have better lung/BP marks, probably runners, probably yogies. Do you know? Have you tried sports training to improve this?
Always excited to watch your presentations .
Thanks Abdelilah!
Now that you've been using the Breather Fit for several months, have you observed any meaningful improvements in your FEV1, BP, and/or lung function? Would you recommend the Breather Fit device? There's also a less expensive inspiratory and expiratory muscle training device called Expand-A-Lung. Have you tried that one? Thank you!
Hey Robert, we're 1 video away from that story (3/5/23)! In hot-off-the-presses news, FEV1 got worse (I may have overtrained with it), whereas BP improved. Is that correlation, or causation? To answer that, we'll also see if those changes went away when I stopped using the Breather Fit. I haven't tried other models, but I am considering repeating the Breather Fit experiment, but training with it less often (not up to 8 min/d, but maybe half that amount).
@@conqueragingordietrying123 Thank you! Looking forward to your upcoming video. I hope you repeat the Breather Fit experiment and can find a training frequency/duration "sweet spot" which results in both improved FEV1 and BP.
Off base question - have you ever tried a keto diet and seen what it did to your blood markers?
It's not off base-the highest that I've gone for fat intake is ~120g/d, and that resulted in more biomarkers going in the wrong direction than right. However, some of that may be driven by dairy SFAs-I'm considering slowly raising my fat intake without cheese and full-fat yogurt to see if the results are repeatable. So hardcore keto no, but relatively higher fat ~44% yes.
@@conqueragingordietrying123 Fantastic insight!
humming can increase nitric oxide and efficiently of gas exchange - I believe Huberman reviewed that research in the past. Have you seen it?
Nope, but I doubt that effect will be as strong as IMST/EMST for lung function.
Do you have HEPA filters in your house?
I do, one in each room
Nebulised glutathione as well as NAC, Astragalus in some data shows beneficial effects for COPD patients.
Some research also suggests NMN may also assist.
what are your thoughts?
The best strategy would be going after the underlying problem in COPD. All those supplements may treat the symptoms, but not necessarily the cause(s).
Time to start playing some kind of wind instrument, lol!
Definitely. I now think that lung function is a dramatically under-appreciated component of aging.
@@conqueragingordietrying123 I wonder if dusting off my trumpet would do me some good. I might scare the dogs though. haha I used to play aloooong time ago.. =)~
@@TGSamantha091 The trumpet or any device that provides resistance is a good idea! Ideally, tracking FEV1 (or other lung function measures) and BP to see if it works...
I'd love to see a comparison between using a device, and simply training with a very thin straw, or fingers mostly blocking the nostrils. It seems like it shouldn't be hard to create your own resistance while breathing, though with a device it's certainly easier to quantify it.
You reminded me of Arnold Jacobs, who was possibly the most influential tuba player in history, and that was despite allegedly having 50% lung capacity due to childhood asthma and COPD. Breathing exercises were his specialty, and his teachings remain influential for all wind players. His self taught understanding of breathing physiology was apparently better than his doctors'. He died at 83, and I can't find his cause of death. Probably not relevant, but I felt like sharing! It would be interesting to see a longevity comparison between different types of musicians.
Definitely, that's a good idea. I haven't seen any studies comparing that yet, though. That's interesting about Arnold Jacobs, and I wonder if wind players live longer than average, especially considering that FEV1 may be a top predictor.
@@conqueragingordietrying123 I did a quick search, and while it doesn't seem like a great study "Lifespan and longevity among representatives of creative professions" which cites "Longevity and some reasons of death of musicians of the 20th century" says Conductors and harpists live the longest, which is probably a wealth/education factor more than anything else.
Several years ago I bought a cheap device online (maybe $3 or $5) that's basically a silicone mouthpiece attached to a simple rotating valve to adjust air resistance. Does the job, but does not allow for independent adjustment of inpiratory vs expiratory pressure.
I'm waiting dr Lustgarten.
Thanks Linda!
Thanks!
Thanks for your support, blaney6591!
@@conqueragingordietrying123 You're welcome. Thank you for the great content! Do you happen to have a formula that uses FEV1 or other pulmonary function markers that can be used to calculate chronological (pulmonary) age?
@@blaney6591 Unfortunately not, at least for now...
I'm ordering one on amazon now.
I love these devices, BUT i cannot discard pranayam and Qigong. As a practitioner of both i'm pretty sure that some techniques will improve this even better.
Awesome topic by the way
any study comparing this to good old yoga (which focuses a lot on vascular health) ?
What is the process you're going to use to improve your breathing reps and sets?
I bought a combined IMST+EMST trainer, and I'm starting today! I'm aiming for 20-30 resisted breaths/d (~70% MIP).
@@conqueragingordietrying123 I'm excited to hear results
Is Lung function correlated with HRV? I feel better respiration when my HRV is high!
That's an interesting comparison-once I have enough data for FEV1, I'll definitely compare them.
Can you put a link to the study/data you used to make the FEV vs Age chart? Thanks.
Definitely-it's in "Spirometry Reference Equations for Central European Populations from School Age to Old Age", and that link is in the video's description.
@@conqueragingordietrying123 thank you
Very, very curious what you have to tell about the brain!
One thing that improved my breathing a lot was speaking voice lessons. I took classes (Freeing the Natural Voice, Level 1 & 2) at The Linklater Center in NYC 5 years ago. The classes were based on Kristen Linklater's speaking voice method. Before the pandemic, the classes were in person. Now they offer classes online as well.
In researching for this video, I came across IMST/EMST for help with voice/singing, too, so that makes sense.
Looking forward to see which respiration training devices you choose
Thanks Ed. I'm leaning towards the Breather Fit, but I'm also considering Expand-A-Lung and Ultrabreathe. I want to start with an affordable trainer first, as each of those are < $60 USD.
@@conqueragingordietrying123 I bought powerbreathe about a year or so ago. I used it once and it is still sitting in the box today. I am not even sure where the box is at the moment.
@@jackbuaer3828 Hmmm, based on the data in the video, it's probably a good idea to use it! I'd track FEV1 and BP, too, so see if they correspondingly improve.
@@conqueragingordietrying123 Well, I do have a problem with BP. I was able to keep the top number 120s and 130s last year with many interventions going, sauna, racquet sports, walking, lifting, hibiscus, ice bath, citrulline beat juice. After I increased my racquet sports training, my BP recently went through the roof into the 150s despite having relatively low bodyfat and a low salt whole foods diet. I made the decision to go on Telmisartan / Amplodine combo to see if I could get it down in the short term.
I do at least 90 minutes of exercise / sauna activity day spread out into 3 or 4 daily sessions. I have changed my 25 minute morning walk with the dog into a jog to see if that helps with cardio measurements.
I might pull out the powerbreathe, but each thing I add to the regimen leads to the possibility of overtraining. I measure my overtraining as to how I feel. My body shuts downs if I do too much and I oversleep. Right now, I have decent energy with what I am doing. The powerbreathe may come out in the future. I have at least located the box.
IDIAG P100 is the best device out there as it adjusts and keeps CO2 steady as well as provide feedback and stats. However, they doubled their price and got so expensive as to price out regular users. Makes me sad.
Great video Mike. I like Airofit fit for inspiratory/expiratory training.
Thanks Lee. Airofit looks good, I'm looking to get the same value for a lower price, for now.
Quercetin alone reduces blood pressure. Could that be associated to reduced brain aging aside all the othet benefits provided by Quercetin?
Can you post data that quercetin reduces BP in RCTs?
Systolic blood pressure is raised due to hardening of the arteries and high blood pressure is a leading predictor of early death. Would be good to know what your techniques can do against this hardening.
I'd have to look to see what'd published in that area, but note that my usual focus is on maximizing health, rather than trying to fix aspects of aging.
when you choose your device to improve your lung function I would be ever so grateful if you could let me know as I am saying to purchase something effective for my mother to improve her lung function
Definitely-I'll post it here on the Community tab,.
@@conqueragingordietrying123 thank you so very much. My mum has copd and it is a terrible worry
Awesome :)
SHBG stands at the second place, but using it as an aging marker is dangerous at least. SHBG also rises with a healthy fiber-rich diet, and low levels of SHBG are linked to several diseases.
Is there published data linking SHBG with fiber intake?
Love this channel! What about a incentive spirometer that the hospitals give patients? Are those very effective?
Thanks Luvly butDeadly! Can resistance be used with an incentive spirometer?
@@conqueragingordietrying123 I've never used one, but I don't think it does. Pursed lip breathing exercises? I look forward to the devices you recommend. Thank you
Mint tea and hibiscus tea may lower blood pressure.
I did see nutritional changes such as following an anti inflammatory diet, beetroot (or extract) and foods know to improve the microbiome can improve lung function along with sauna and specific breathing exercises such as Wim Hoff style sessions.
I’m a long time 10k runner. My average Bp is 100/60. All these years I think running has so far saved me from chronic diseases, previous bad eating habits etc. I used to teach asthmatics how to do peak flow. I wished I’ve jotted down the numbers I use to get way back then.
100/60 is great KoiRun. It could go either way with endurance athletes-anecdotally, I've seen that for every 1 that is in good health with good eating habits, there are many more with terrible eating habits.
It’s a bit low and sometimes I can tell.
Michael, would you please talk about orthostatic hypotension? I think it’s a huge risk factor for the elderly in regards to falls. Mid sleep getting up micturition is a common occurrence that plays a role.
I also now found a couple of peak flow meters. I tested 600 L/min in one and 575 in the other. Does reading make sense? Peak flow the same as FEV1?
@@KoiRun50 Both values are very good, they're better than mine (average = 537 L/min). My understanding is that FEV1 is a better measure of lung function, but Peak flow can be used where FEV1 is not available.
Thanks Michael for letting me know about this very easy age related parameter. I will keep track from now on.
I would say you don't need to buy an imst+emst as everyone has one built in. When we exercise more it is normal to switch from nose to mouth breathing. If you don't switch you are automatically getting built in resistance. You can even modify this with tape and breathing strips. As many noses are different you won't have the same range but as your study is n=1 it shouldn't matter.
The data in the video shows that FEV1 improvement didn't happen with MIP < 50%, so I'll need some type of device to offer breathing resistance.
Why not brain MRI? Cost?
Most physicians are already wary to blood test multiple times/yr, and I don't see any way that they'd let me get multiple MRIs/yr for eat blood test, even without the cost.
Perhaps it would be helpful just to get a baseline and then lower frequency for the MRI than for blood tests? Annual or every two years? Hopefully you still will get lots of data points :)
@@christopherbrand5360 Knowing the battles that I've had with GPs just for blood tests, I think it will be more difficult (unfortunately) to convince an MD to get regular MRIs, even 1x/2 years.
The danger of misinterpreting an unclear scan, thus creating a false positive, is not worth it.
please can you remind me of the best sources to look at when searching for the optimal blood lab results?
Ha, here! I've summarized most of the big picture biomarkers in videos. If not, my website, too. Everything else is reference-range based, which isn't based on what's optimal.
@@conqueragingordietrying123 o OK, I was looking for a summary guide. I'll check your website then thank you. But if you come across anything please do let me know. I subscribe so will see your notifications and really appreciate your advise. I have my mother's blood results now and want to look at setting some realistic goals to improve her health and overall longevity
Have you measured your Vo2Max? Do you believe your relatively low activity levels (which you do intentionally to ''preserve'' higher HRV) may come at the cost of a low Vo2Max, a low FEV1, and in the long-term, low HRV itself?
Most of my athletes with high Vo2Maxes (estimated via running tests) have very high FEV1 for their age(measured by incentive spirometer). They also have low resting HR's, and high HRV's (according to various devices, including Whoop, Fitbits, Apple Watches, Garmins, and Oura Rings).
I've measured VO2max 3x since 2010, and it was in the 40-45 range. I haven't tested it in about 5 years, though. Based on my 2 eighty-minute workouts/week, I meet the Physical Activity Guidelines for Americans, and that doesn't include all the walking that I do otherwise-it's hard to say that my activity levels are low.
In terms of titrating activity to optimize both RHR and HRV, will that limit VO2max? Probably, but I'd rather not be overtrained. The goal is fitness as a component of longevity, not fitness without longevity.
Great presentation as always, thanks!
Libert et al.'s tables of top predictors of age are very interesting. I'm a little surprised that SHBG and testosterone separately are that high in the list for males because mutations in the SHBG gene (rs12150660 and rs1799941) can give you SHBG and testosterone levels that are off the charts and that are not indicative of age. I would have thought that *bioavailable* testosterone (or free testosterone) is more universally comparable, which takes both total testosterone and SHBG into account.
Thanks excellent!
Love your channel. Have same Spiro device and similar issues, so I will be following your journey closely. Did any of the studies discuss through what mechanism improved FEV1 lowers BP?
I can imagine systolic BP and SHBG being on top of waiting list for BPB. I doubt the inclusion of insulin because low insulin can indicate low insulin resistance and advanced age at the same time--a mixed signal.
I recently bought an IMST device after having my whole genome decoded and finding out I have low Alpha-1 Antitrypsin levels which puts me at greater risk of COPD and Pneumonia. It would be interesting to see how you would combine knowledge of weaknesses in your personal genome in combination with biomarkers to extend lifespan as I feel you need both to really Conquer Aging.
Have you increased lung function with the IMST device? I have 23andme data, but I pay far less attention to the genomic data, as it indicates what may be possible, whereas circulating biomarkers are more indicative of active processes.
@@conqueragingordietrying123 I just started so don't have enough data yet but will be monitoring my blood pressure to see if it makes a difference, the nice thing about genomic data is that it can also tell you how well you will respond to different supplements or substances, whether you are hypersensitive or where they could be toxic or if you would respond well, using my full genome with the geneticgenie site has been a gold mine for me in this regard in addition to health risks, considering whole genome sequencing is now 300 dollars its well worth it IMHO.
@@Finnfreya1 nebula genomics