Serotonin Syndrome Explained (Serotonin Toxicity)
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- Опубликовано: 31 май 2024
- Serotonin syndrome, also known as serotonin toxicity is a potential life threatening condition due to excessive serotonin levels in the body. In this video we look at the symptoms, diagnosis including Hunter Serotonin Toxicity Criteria and treatment.
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Video Timestamps:
0:00 What is Serotonin Syndrome?
0:25 Serotonin Syndrome Pathophysiology
2:03 Serotonin Syndrome Symptoms
3:26 Serotonin Syndrome Risk Factors
4:08 Serotonin Syndrome Diagnosis (Hunter Serotonin Toxicity Criteria)
5:16 Serotonin Syndrome Treatment
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Disclaimer: Please remember this video and all content from Rhesus Medicine is for educational and entertainment purposes only and is not a guide to diagnose or to treat any form of condition. The content is not to be used to guide clinical practice and is not medical advice. Please consult a healthcare professional for medical advice.
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Video Timestamps:
0:00 What is Serotonin Syndrome?
0:25 Serotonin Syndrome Pathophysiology
2:03 Serotonin Syndrome Symptoms
3:26 Serotonin Syndrome Risk Factors
4:08 Serotonin Syndrome Diagnosis (Hunter Serotonin Toxicity Criteria)
5:16 Serotonin Syndrome Treatment
that heartbeat at the start has been the smartest intro that I have ever seen. You probably already know what I mean
I had serotonin syndrome caused by citalopram, I spent a month in a coma and now have epilepsy. Ruined my life. Lost my job and driver’s license.
So sorry to hear that friend
🙏🙏🙏 so sorry prayers
How did u get it
@@greendevul anti anxiety medication mixed with painkillers. I didn’t know you couldn’t mix them, I was on holiday and had a terrible headache so took some painkillers, next day I was in ICU on full life support.
@Adam Murray dang I will be praying for u do u know if u can get that by also taken benadrills or melatonin wit it
I think I once had (a mild case of) this. Took DXM with beer while using 5-HTP and mirtatzapine regularly as I didn't know about the interactions. Felt very dizzy, jittery, sweaty and disoriented for like a week.
hey pal I have just recently and unfortuenly had the exact same experience with the same cocktail of substances you took minus mirta I took a low dose dxm dose with 300mg of 5htp (big mistake, folk may say it can't cause SS like ssris of any type do yet there are others out there who had the same thing), caused mild/moderate ss, went away, drank a few beers then it came back and I went to the ER. SS even mild is nightmare shit I felt like I was being scorched alive in tandem with a bad time of dxm the SS put me in.
i see im far from the only one there are others on the reddit sub who experienced the same. it lasted a week for you :( sorry to hear it must of been awful it's day two-three for me I am fairly back to normal.
i might’ve had this one time i smoked like three blunts and i was also on a new dose of lexapro i got super sick, hella pale and my mind was super disoriented and i felt like i was gonna die
but i was not greening out , trust me i’ve never in my life thrown up from smoking too much weed and my tolerance was very high, i know what greening out feels like and it’s never made me physically ill like that
WELL DONE. THE BODY TEMP SWING HAS ALWAYS BLOWN ME AWAY.
IT CAN BE A 100 DEGREES IN HERE AND I'M STILL SHIVERING AND SHAKING, FREEZING MY ASS OFF.
I think my mom had this last week. It was awful. She’s on 2 or 3 antidepressants. One benzodiazepine. And other meds. She was vomiting, pail, heart palpitations. Had falls and passed out once. It’s no joke!
Benzo is the worst thing I have ever experienced. No one (but mom) believes me because they never been experience anything on it, but it made me have a physcosis, which I had never experienced before and never after, had to be hospitalized, it was the scariest thing ever!!!
Benzos don’t cause serotonin syndrome. Benzos are a central nervous system drug. Matter or fact, benzos are the first line to treat serotonin syndrome. But may I ask which antidepressants? I just started one and one only. Taken remeron and celexa for years without having serotonin syndrome. But now I’m getting back on celexa to quit Kratom. I’m just curious for people who had it or know people what the actually drugs were that caused it
I was on 6 different meds that affected serotonin production when i decided to experiment with Lsd. I didn't know about serotonin sydrome and i had 14 seizures in 2 hours and almost died.
I had my SSRIS increased due to higher anxiety
1 day later, I had the runs, headaches, trembling, muscles twitches, sweating…it was mild but still, I needed at least a week to recover at home 😮
Yup. Celexa with trazedone did it to me. Currently recovering
You’re a fantastic teacher.
Thank you! 😊
Very nice work
indeed
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I took Valerian root + Duloxetine and was so sick had to go to er. Severe weakness, fever, sweating, vomiting etc it was awful. The Activated Charcoal I took at home helped alot. Unfortunately they didn't help me the hospital at all except for an anti- nausea pill. It was a joke
Oh shit, looks like I need to talk to my psychiatrist, how the hell did he not pick up on all the concerningly overlapping symptoms I've mentioned in relation to my medication?
Any luck with finding a solution?
i have it too. going through it right now. it is awful
. I was on trazedone and they added celexa and I was feeling so bad I added HydrOXYzine and promethazine to help. Bad idea. I kept going to hospital because I thought I was having seizures. Dizzy, nausea, vomiting, diarrhea, tremors, trance spells, head shaking, oxygen was bad, agitation, insomnia, sweating, clenching jaw, neurological issues, list goes on. I didn't have a fever. I'm currently recovering. Horrible
Exactly what my thought is 🥺
What about a mild reaction to a serotonergic agent, such as rigid neck muscles about 30 minutes after a 1st dose of escitalopram, or an hour after a trial dose of venlafaxine? And could someone with a CYP2C19 mutation, an "intermediate 5-HT metabolizer," develop a chronic high-ish level of serotonin that could cause a subjective sense of facial warmth, elevated temp of 99-100.4, myalgias, and chronically stiff neck and upper back muscles? I found Dr Sanjay Prakash's articles. Riffing from there and from your video. Thank you.
had this yesterday for the second time lmao it feels hard to breathe for days afterwards
Ong
I took alcohol and Xanax (what I was told) and I believe I had this, I still have residual effects like a strange feeling every time I yawn, and a strange feeling that’s hard to describe in my stomach
Uh, I might need to check to my doctor. I've been having heart palpitations, nausea, want to vomit and lost appetite, and twitching legs too.... It's been going for three weeks too...
How are you now?
Good 👍
An unknown combo to be careful of is the OTC supplement 5HTP and onedestrone (zofran) os dangerous. But taking along with buspar, and hydroxizine even worse. Be sure you talk to your doctor before adding any supplements. I made this mistake and it was a terrible!
I think 5htp, unless used with major caution and knowledge is just a risky substance in general ya gonna take something else likely within the timeframe of using 5htp and then this happens.
Wait tell me more about this…
@@meaganyn what would you like me to elaborate on?
@@tggraham3321 well I take all of those except not buspar … I’ve def taken 5htp, hydroxyzine, magnesium, tart cherry, melatonin at night all together… why is it so bad?
Had this yesterday with a combination of Lexapro and paroxatine i almost died last night.
How about mdma and using 5htp to help r
Heal the serotonin receptors
If you have seretonin syndrome Just take a long break from all drugs, go smoke some weed
@@DxmAddict I don't have it. Never have just wondering about mdma and 5htp to help revover
@@edgarcasey1840if you happened to be a rare case of getting serotonin syndrome, because it is rare which people don’t realize. Why on earth would you combine those 2?! That’s asking your serotonin syndrome to amplify
@@edgarcasey1840Mdma is neurotoxic to the serotonergic neurotransmission system, I can’t imagine that would help at all. 5-htp would probably be fine a while after you have serotonin syndrome, as it’s not a serotonin releasing agent or SERT inhibitor.
I'm on ssri and I took 450 mg of dxm and gave Myself this it sucked
My daughter (21 years) had this within hours/days of being put on starting dose 20mg of Citalopram.
😢
Is she okay, i hope so. I am having it right now too and anxious
@@user-ri4fy3td1eI hope everything was ok I'm not sure if I was having it but the symptoms were bad all day
@@user-ri4fy3td1edid you recover alright?
So I take Zoloft on a regular basis. Last night I was under the influence of marijuana, and realized I had forgotten to take my Zoloft during the day. I took it while high and what I experienced was scary to say the least. Uncontrollable shaking, everything looked fuzzy, and I almost passed out at one point. Could the combination of Zoloft with being high have cause Serotonin Syndrome?
No you were just probably too high lol weed doesn’t effect serotonin receptors
@@DeltaReviews420 WRONG
FU
@@jobalogo383 ? Please do some research, your language indicates your arrogance.
@@DeltaReviews420 sadly depending on the strain it can be a downer also.
@@walterstanford8162 strain has little to no effect on the high it’s all placebo
This has happened to me I’m having really bad anxiety because of it and I don’t know how to get rid of it I feel like nothing is helping and my doctors can’t see me til Wednesday
Sleep
Because of anxiety and panick attacks I quit caffeine( coffee, chocolate, green tea, coca-cola/pepsi, energy drinks) two weeks ago. My panick attacks were so bad I also had them in my sleep.
At first I quit for a week, no more p.a, so I drank only one coffee and panick attacks came back the same day.
Caffeine fu*ks up your brain's sensitivity. I drink only water now.
I still have withdrawals, and can't concentrate, but my sleep improved, no panic attacks, anxiety, etc. Is hard but totally worth it. It will take a month I guess to clear up completely.
Hope it helps.
So I’m on lexapro and a while back I was doing cocaine and ketamine while on the lexapro. I believe I had serotonin syndrome but it only lasted for 5 mins. It felt like a panic attack coming on except my hands and lip muscles because stiff as a board and I couldn’t talk or move my fingers. I started panicking. I was sweating profoundly and my pupils were dilated. I’m sure it was the interactions between everything but does it sound like that’s what happened? Should I have gone to the hospital?
You should probably stop doing so much coke
Any amphetamine being mixed with a ssri is extremely inadvisable and yes you could have experienced that. Please be careful
can seritionine syndrome get cause my zofran and smoking pot?
I took 100mg of 5htp and 4 days later 50mg of 5htp. My calves locked up for 3 days, i had extreme dry eyes, tingling in toes and fingertips, felt like my heart was racing and had major anger swings. I have been to the emergency room and to a regular doctors have gotten no help at all. They referred me to a neurologist but cant get in until two months from now. I really don't no what to do but need serious help.
Stop taking the medication
Just stop taking all these medications, most doctors don’t know these ADR…
Came her to learn why my seratonin is so high. Jesus made me this way. I don’t eat a certain way or take medication I’m just uncharacteristically happy. 😂😅😂
Small correction at 1:13, N in SNRI is not noradrenaline but norepinephrine :)
They are exactly the same thing mate. One is just an American convention.
@@KezzaPwNz oh nice, you're right. Thanks for teaching me something new!
@@michalbrz No worries - wouldn't be medicine if you weren't constantly learning new things each day.
watching this so I remember to follow the week per plat rule of dxm
I tried to od on trazodone,took about twenty pills went to sleep its going on day four after and my ideation went away should I go to the doctor or will it go away on its own, I threw all my meds out
go check in with you doctor man better safe then sorry
Does serotonin syndrome cause hypertension tension
Yes
How come a psychiatrist bescribe SSRI, benzodiazepines, adhd drugs together? Isn’t that dangerous 😊
I'm just trying to make sure if I eat a full pie of spinach quiche I wont get these symptoms... I heard spinach and eggs have serotonin and I am about to pig out✌
…
buspar!
I became pale as a paper sheet and my mouth was red and extremely dry, I had tachycardia and vomited on my friends, I woke up at 6am with a lot of diarrhea, almost shat in my underwear and my bed 😂💩
I took Escitalopram 20mg, Vyvanse 50mg and a looot of weed 🌿.
Everytime I mix this substances I have diarrhea and serotonin syndrome symptoms.
3:16
4:30
JESUS saves Roman’s 10:9-11!!!
HE saves our soul but not always the body.
AMEN
It certainly wasn't Jesus that treated me in the ambulance and er when I had 14 seizures in 2 hours and almost died from serotonin syndrome. They looked more like doctors.
@@samr.3515 Anothwr axample of atheista being dumb 😂😂😂😂 no one needs to even say anything more to this fool right here. We're praying for you, lil bro.
You are on the right track. The voice needs to change so that people can take it seriously!
what heppens when we drug kids..
This is not drugs like coke or crack. This is medically necessary for some people to live functioning lives.
Asswashganda