Do I Need to Worry About Serotonin Syndrome?

Serotonin Syndrome is a potentially fatal condition, characterized by confusion, fever, and muscle spasms, that can occur when there is too much serotonin in the synaptic cleft. It almost always occurs from taking multiple serotonin boosting drugs, or from massive overdoses. The vast majority of people who develop Serotonin Toxicity have milder versions, and recover fully. Despite numerous warning from the FDA and pharmacies, most people on SSRI, even in combination with other medications, such as trazodone, Buspar (buspirone), or Wellbutrin (bupropion), are unlikely to develop this condition.