Glycogen metabolism

[@m.eminkokturk2604]

Wow, you summarized every and each detail just in 10 minutes. I really liked the animations and how to the point this video is.

[@osmosis]

Thank you! Glad you liked it! 🙏🏽

[@Xxwwks]

I have a question
Glycogen is present in all except:
Blood
Brain
Tissue
Heart

[@vanessahnatashahambala2004]

@@Xxwwks l think it's except the brain

[@senseimusic7082]

1 hour before the exam

[@Phantom_Kraken]

Been there before dude 😭

[@L0V3.Y0V]

@@Phantom_Kraken😂😂

[@emiliatadie8054]

Same 😭

[@ayeshafatima122]

No one cares😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒😒

[@Dara-z8g]

33 minutes🔥

[@bhavleen2737]

Glucose and Glycogen
Glucose is a 6-carbon molecule used to make energy in the form of ATP
Excess glucose is stored in skeletal muscle cells and liver cells as glycogen
Glycogen is a large, branched molecule made up of glucose molecules linked by glycosidic bonds
Glycogen Synthesis
Four main steps in glycogen synthesis:
Attaching UDP molecule to glucose
Attaching glucose part of UDP-glucose to glycogen primer
Adding more glucose molecules to the primer
Adding branches to the glycogen molecule
Enzymes involved: phosphoglucomutase, UDP-glucose pyrophosphorylase, glycogen synthase, and glycogenin
Glycogen Breakdown
Glycogen breakdown occurs in response to low blood glucose levels
Enzymes involved: glycogen phosphorylase, debranching enzyme, and phosphoglucomutase
Breakdown occurs in liver and skeletal muscle cells, with different enzymes used in each tissue
Regulation of Glycogen Metabolism
Two pancreatic hormones regulate glycogen metabolism: insulin and glucagon
Insulin promotes glycogen synthesis and inhibits glycogen breakdown
Glucagon promotes glycogen breakdown and inhibits glycogen synthesis
Regulation occurs through phosphorylation and dephosphorylation of enzymes involved in glycogen synthesis and breakdown

[@bkadam8654]

Straight simple and comprehensive i appreciate your work the animation makes me understand much easier than just words

[@monicasebrandt7951]

This helped me so much!!!! I was worried about this topic on my biochem test tomorrow, but I understand so much better now.

[@osmosis]

Hi Monica,
We're truly glad we can be of help! Let us know if you need anything else, feel free to reach out to [e-mail] :)

[@HypeSwag5141]

This is super helpful for my first exam ever in dental school!

[@osmosis]

Glad it was helpful and best of luck! 😊

[@stellawanjiku4362]

Please keep on making more biochem videos,they are so helpful.Thankyouuuuuu😊

[@majocaceres5283]

As a visual learner, THANK YOU!!

[@osmosis]

Most welcome, Majo! 🙏🏼

[@nurangolbasi9970]

This was amazing. Thank you so much! This helped me reconsolidate everything I needed for the MCAT, and the animation was beautiful and concise.

[@deezjulio3578]

the amount of concept in just 10 minutes is just insane! great video for a quick revision of the topic.

[@osmosis]

Thanks! 🥰❤️🙏🏼

[@ThelxoxlGirls]

This video is a godsend, thank you so much for making it! Clear, concise, and quick. Good stuff!

[@osmosis]

Happy to help! 🙏🏼

[@shikhajasani8155]

Thank You Very Much! Very useful! Just watching it before 5 hours to my exam!!

[@whatsappstatusmaster1839]

I have same stituation

[@Org9mdi63]

Same

[@ayeshafatima122]

I am in a similiar situation😂

[@AhMedicine23]

Great video. You guys make complicated stuff go easy as always. 🤗

[@osmosis]

Glad you think so, Ahmed! 💖

[@evaristogodwintolentinov7305]

Thank you Osmosis. you are my saviour. Currently reviewing for the Physician Licensure Examination
. I can easily understand because of your animation. BIG THANK YOU.

[@osmosis]

Most welcome and best of luck! 💫 🥰 💖

[@nityaasrimanikavasagam3619]

thank you...it was way better than my lecturer's explanation.

[@osmosis]

Glad our video is able to help! 😊

[@abdallahdawod5957]

2:49 the right Pyrophosphorylase cuts one phosphate from glucose-1-phosphate and the second frome UTP ☺️

[@gauriscreation8953]

Sir animation plus your teaching style of easy explaining is awesome

[@santicruz4012]

This was so easy to understand and the animations make it fun and interesting! Thaaaaaanks

[@osmosis]

Glad you liked it, Santi! 😊

[@gyoseph8679]

This guy is a genius at simplifying complicated stuff

[@osmosis]

Glad you think so, Joseph! 🧠 🤓🫀

[@inevitable749]

Thankuuuuu soooooo muchhhh. Pls make more such vds on biochem. Like protein structure, folding

[@tariqueazam8214]

Brilliant explanation through beautiful animation 🙏

[@DivyaGoswami-j2o]

Does glycogen metabolism include both glycogenesis and glycogenolysis?

[@Khushbu_mishra_04]

Thank you so much my all doubt is clear in this video very nice video 🤗

[@osmosis]

Happy to help 🙏🏼

[@chatzzz9063]

channels like this are so helpful, thank you so much!

[@osmosis]

You're very welcome! 💕

[@poushaleedey9796]

Best video on this topic i have come across.

[@osmosis]

Wow, thanks, Poushalee! 💙

[@noor37083]

May Allah guide you and grant you Janna for spreading knowledge in a sincere way 🌸🤲

[@chenlongzan463]

the enzymes are so cute. Thanks for putting in the effort to make the video entertaining. Helps with getting through the content.

[@osmosis]

Glad you enjoyed! 🥰❤️🙏🏼

[@jokersghan4637]

Sir Your Teaching and Explaning Method is fantastic 😍 Thank you very much Sir

[@osmosis]

You are most welcome! 🙌🏼

[@daughteroflight8624]

Thank you Osmosis 💗

[@osmosis]

Any time! ❤️

[@amirhoseingholizade8614]

where the glycogen is save on cell?in endopelasmic reticulum?

[@3A.m.Motivation]

Thorough explanation with complete understanding , thanks so much...🙌🙌🙌

[@osmosis]

Thanks for the feedback, Mike! Glad you liked it! 🤓

[@SaravananS-gc4kt]

Thank you sir
Very nice presentation 👏👏👏

[@DARKFEARR]

5 minutes before exam at 2x speed

[@hajar.t2004]

😂😂😂😂😂

[@shielalynares9309]

I feel you bruh 🤧

[@irtamalik1778]

Beyond amazing! What an apt explanation!

[@osmosis]

Glad you liked it! 😊

[@Livesimple022]

Thanku so much for making this video , it helped me to understand this topic clearly.

[@osmosis]

Glad to hear that! 😊

[@056vatsalapandey3]

i cannot believe you explained all that in 9 minutes. i took my teacher 4-5 hours and I still didn't get it

[@osmosis]

Glad to help, Vatsala! 🙏🏼

[@sorlos]

Thank you!!

[@osmosis]

You're welcome, Laboni! 😊

[@indianb1918]

Good explanation. Cheers.

[@osmosis]

You're welcome! ❤️

[@Sara-bv2oj]

This video very helpful , Thank you.

[@stCentury-mg6gu]

Thank you❤️ was really helpful!

[@ranjaniHeHe]

Thank you!❤

[@osmosis]

You're welcome! 😊

[@Sqqqqqqq-q3k]

to the point 👌
thank you osmosis ❤❤

[@osmosis]

Most welcome! 😊

[@Whiteswanj]

thank u💚

[@raquelcardenas9149]

This was so helpful! It helped me understand everything, thank you so much!!!

[@osmosis]

Glad to help, Raquel! 🥰

[@sarahsaeed2007]

very helpful...thanku so much

[@haseebsheikh6551]

Excellent depiction

[@osmosis]

Thanks, Haseeb! 😊

[@jinx2873]

thank you

[@owenmooya6355]

I really appreciate this perfect work, I understand this now

[@osmosis]

Thanks for appreciating this, Owen! 💕

[@djkunect]

beautiful explanation

[@osmosis]

Glad you think so, Ayeni! 💙

[@lillcyan7607]

Thank you💞

[@Alaska-Med]

this was awesome! thank you!!

[@osmosis]

Our pleasure, Leif! 😊

[@dyt.fundagargac9988]

Thank you for presentation..

[@hassanatoujallow2795]

Thank you❤

[@osmosis]

You're welcome, Hassan! 😊

[@Yoooomanwhatsup]

Just wow . It was all clear to me . Thanks for such an amazing video

[@osmosis]

Always our pleasure to help, Debashish! 🙏🏼

[@tipimebak7105]

Great explanation thank you so much

[@osmosis]

Our pleasure, Tipime! 💖

[@ansaqadeer5087]

Amazing description 👏

[@osmosis]

Thanks, Ansa! 🥰

[@gopala555]

Nice presentation, I have question about the degradation of glycogen using phosphoric acid. could you please explain if phosphoric acid can degrade glycogen.

[@shrinishachandrasegaran1020]

Thank you ♥️its very helpful

[@maysammohyeldinn8243]

Very simple and great job! 🔥

[@osmosis]

Thanks, Maysam! 🙏🏻

[@meramera9841]

Great video
Thanks you ❤

[@osmosis]

Thank you too! 😊

[@Freephalstine-h8n]

اگولك خالي شو بالبداية گلت الابنيفرين ينفرز من الغدة الكظرية يزيد ضربات القلب وبعدها گلت يسوي مثل شغل glocago الي ينفرز من البنكرياس في تحطيم كلايكوجين الكبد شسالفه

[@noor37083]

الابنفرين عنده اكثر من وظيفة يزيد دقات القلب وكذلك يساعد بتحطيم ال glycogen الي مخزون بالعضلات وعنده بعد وظائف اخرى

[@sarasleeem5838]

I really do appreciate the effort you put into these videos ❤
But I think the rhythm is very consistent that I keep losing focus and replaying the video, almost as if the narrator's reading and not explaining.
Everything else is absolutely great ❤

[@osmosis]

Thanks for the feedback, Sara! 💕

[@visibletoallusersonyoutube1222]

I wasted 4 whole ass hours trying to understand it from that damn book 😭 should've watched this instead

[@nehabharali3711]

Superbb explanation tysm

[@osmosis]

Most welcome, Neha! 😊

[@n_718]

That was very helpful I understood so well, good job sir :)

[@ibrahimalhennawi2834]

a summary of a 2 hours lecture in just 10 minutes WOW

[@osmosis]

We hope this helped, Ibrahim! 🙏🏼

[@Schneewolke]

1:19 only GLUT4 is insulin dependent ?

[@marcosfloresgutierrez9692]

I hope that you read my commentary
I´m studen of nutrition here in Mexico and your videos helps me to practice my english and to review the topics :'D

[@osmosis]

That's great! Thanks for letting us know, Marcos! 🥰❤️🙏🏼

[@ZerihunMekonen-u7i]

Wow amazing thank you so much🙏

[@osmosis]

You’re welcome! 😊

[@bayancoldplay]

Wow this effort is just impressive ! Thank you so much

[@osmosis]

Glad you like it, Bayan! 💕

[@mnster8824]

I didn't understand why the udp while the glucose can make abond directly

[@valeriabarrera4382]

Where does step 2 begin? That's the only part i don't understand :(

[@lulukbella]

Thank you very very very much

[@dilshaponnu4863]

Please add a vdo of cholesterol metabolism plsss

[@osmosis]

Hi Dilsha! We have a video on this topic that you may watch over at osmosis.org anytime! You may signup for the 7-day free trial (no credit card needed) to access our video library 😊

[@aprillaurenpamaran3801]

Hi! Can you please make a video about Carbohydrate Metabolism? I would appreciate it very much! Thank you.

[@osmosis]

Hi April! Thanks for leaving your comment here. Please do instead send us an email at [e-mail] so we can check your request. Thanks!

[@bilqisnjama1387]

awesome,,,
just wonderfully awesome

[@osmosis]

Thank you, Bilqis! Cheers! ❤️

[@_phs]

From Iraq thanks ♥️♥️♥️

[@scumstuff7374]

Im having trouble understanding what you mean at 2:38. "Which uniquely comes in the form of uridine triphosphate". Im so confused here

[@osmosis]

Hi there, thank you for your feedback. Please do send us an email so we can connect you with our content team. [e-mail] :)

[@lolololololo2509]

On point video ❤❤❤❤❤❤

[@osmosis]

Thanks! ! 💫 🥰 💖

[@arifali6762]

Great info thx 🙏

[@ItzWhitedevil]

Awesome broh

[@simranlakhanpal4753]

thank u very much

[@suprajamkodanch6928]

U r just amazing!😮

[@osmosis]

Thanks, Supraja! 😊

[@Twinkle_Agrahari]

Thanks a ton....

[@osmosis]

Most welcome! 🥰

[@rejeannedube4226]

Thank you very much. Super.💝

[@osmosis]

Welcome, Réjeanne! 😊

[@anitas837]

liver cells have glycogen.. in what form those glycogens are stored, as fat or glucose ??

[@HariKrishnan-nm3lx]

Good explanation....would like to fund you in future after I get a job😅

[@bhavishuvishu5071]

I love it!

[@myra9250]

Thankyouu so much!!

[@osmosis]

Most welcome! 😊

[@thefenerbahcesk4156]

Since diabetics have less intracellular insulin, do they have more glycogen?

[@BeulahKuku]

Guessing not because insulin also activates enzymes to do glycogenesis, (creation of glycogen, as this video shows) which causes the conc. Of glucose in the blood to decrease, serving it's purpose.

[@noahatkins8087]

I swear the voice is the same guy who runs Science Simplified

[@LegendLegend-g5z]

Half an hour before quiz😂

[@RBmusic2000]

Still none the wiser to following this. Such a long , complicated, process.

[@khuziwesithole6719]

Just watch it over and over again until you learn it subliminally 🤷🏿‍♀️

[@muyta862]

How u made it soo easy good job

[@osmosis]

Thank you, Maram! 😊

[@aaiyshasiddiqui3519]

Great

[@AlakaAcharya]

Great!

[@osmosis]

Thanks, Alaka! ❤️

[@MajdTaher]

قبل ما شوف المقطع هاد نفسو الـ glycolysis ؟

[@dilshaponnu4863]

Great🥳🥳

[@osmosis]

Thanks, Dilsha! 🥰

[@yaraafawzi6545]

IM LITERALLY GONNA DIE THANK YOU SO MUCH

[@nurullahnafibd]

You didn't explain step 2,3 & 4