Pharmacology of Benzodiazepines - Mechanism of action , uses , side effects : Fmge and neet pg

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  • Опубликовано: 9 ноя 2024

Комментарии • 64

  • @srabchun
    @srabchun 3 года назад +6

    Two years into taking clobazam, I started to not feel like myself. I feel as if I am just existing. I have moments where its as if someone just hit a reset button in my brain. Because I cant remember anything about the day(temporarily). And the whole time I have been on it, it never stopped a seizure. It just changed the way it happens. I know my triggers. Certain foods. If I avoid them, I don't have any seizures. But I am now weaning off the medication, because it caused my testosterone levels to become well below normal. For my age the normal range is 350 to 1100. My T level is at 21. I am now needing to use testosterone replacement therapy injections to get my levels back to healthy numbers. Hopefully once off this drug, my T levels with stabilize on their own.

    • @unknownbeliever4660
      @unknownbeliever4660 3 года назад

      do exercise mr scott. eat healthy food which increase testosterone ...

    • @srabchun
      @srabchun 3 года назад

      @@unknownbeliever4660 I do eat heathy. Fruits, vegetables, nuts, fish, low carbs and plenty of water. Every day. And I don’t drink alcohol. So it’s not my diet. I also have a very physical job. So I get plenty of exercise. A friend of mine is on Xanax. Which is also a benzo. And he is having the same issue with his T levels. I had no issues until I started taking this medication.

    • @abcd-xc9oo
      @abcd-xc9oo 3 года назад +3

      Are you still on clobazam? If so, getting off it can only help you unfortunately, withdrawal from benzos is hell but there are many new techniques that have emerged to minimize benzo wthd symptoms and maximize recovery
      One is where, in an clinical setting, they pump you full of anti epileptics and administer a Powerful gaba receptor antagonist, gabaR antagonists work oppositely of benzos, this procedure cause your brain to regenerate damaged gaba receptors from chronic benzo use
      Another one is : it's not very official or recommended, it is managing the wthd yourself using various other medications that do not work on gaba receptors but manage the wthd symptoms
      One such medication is memantine, 40mg/day max in combination with
      0.1mg.clonidine(this one is to only be used for a week maximum, it helps with sleep but can mess with blood pressure in long term)
      Memantine is recommended to be used for a couple of weeks to months until the point where wthd symptoms are benign, memantine doesn't have any wthd of its own and has been studied in alcohol wthd where it worked wonders, alcohol has similar mechanism to benzos
      As for epilepsy, use a modern anti-epileptic like levetiracetam since new generation anti-epileptic have fewer side effects
      It would be wise to consult with a doc, and btw, long term benzo use is likely to increase risk of neurological disorders such as dementia

    • @srabchun
      @srabchun 3 года назад

      @@abcd-xc9oo Fortunately no, I am no longer on clobazam. The main withdrawal I experienced was multiple auras daily. And one grand mal seizure. My new neuro recently put me on Briviact. I have not felt this normal in about 15yrs. Now I have no auras. No seizures. And all without a benzo. But thank you for taking the time to give me all of that information.

  • @sushmisushmitha6884
    @sushmisushmitha6884 Год назад +3

    Thank u so Much Sirr Than Reading in Book by ur explanation I understood Totally🙏😍

  • @ankushfreefire9687
    @ankushfreefire9687 Год назад +1

    You are god of pharmacology ❤

  • @souravbarua9943
    @souravbarua9943 2 года назад +3

    Thank you sir. great way of teaching and easy to understand. Its help me a lot

  • @ikshwakumohapatra8339
    @ikshwakumohapatra8339 2 месяца назад +1

    Thank you so much Sir for this awesome session k 🙂🙏🏻

  • @NewMindGarden
    @NewMindGarden 3 года назад +1

    Very useful video.. 👍👍

  • @prasadthorat824
    @prasadthorat824 2 года назад

    nicely explain sir.......thanks u👍

  • @thahirnajip9318
    @thahirnajip9318 3 года назад +1

    Awesome sir

  • @souvikadak1360
    @souvikadak1360 3 года назад +1

    Awesome 👍👍👍👍

  • @chandnimiyatra7533
    @chandnimiyatra7533 2 года назад

    Good lec sir

  • @sunnygibbs925
    @sunnygibbs925 2 года назад

    What about the side effects?

  • @durrekamil6711
    @durrekamil6711 5 лет назад +1

    Great sir

  • @shadilhassan6890
    @shadilhassan6890 3 года назад

    I am taking these drugs for Las t 3 years are they dangerous

  • @eveshkumar1012
    @eveshkumar1012 3 года назад +1

    Sir,thoda Hindi me bhi btaye kariye..🙏🏻

  • @ramprasadpokhrel9895
    @ramprasadpokhrel9895 3 года назад

    I'm taking Clobazam since 1 and half year. And later added Divalproex but my seizure never controlled and quit the divalproex and now taking Lacosamide with Clobazam but still my seizure hasn't stopped. My diagnosis was calciofied granuloma related to neurocysticercosis and left mesial temporal sclerosis. Now lost of hope my seizure will control with any kind of medicines. Only increasing dependency of benzo medicine. Now want to quit medicine.

    • @sandyananjegowda9435
      @sandyananjegowda9435 3 года назад

      Try Levitiracitum
      750 mg +750
      2 times a day
      Best medicine for seizures due to neurocystecercosis

  • @StudentNoor
    @StudentNoor Год назад

    Which is the most sedating of these four benzos?

    • @joditercero8003
      @joditercero8003 7 месяцев назад

      There are more than four.
      Midazolam is used in the death sentence protocol. Temazepam is the most sedating from my understanding. I could be wrong

  • @MK-pl4fr
    @MK-pl4fr 2 года назад +1

    I tore many ligaments and tendons due to benzos induced muscle weakness.

    • @uyoebyik
      @uyoebyik 2 года назад +1

      Same here and doctor said I have fibromyalgia. I believe this is damage because of long-term benzodiazepine use

    • @MK-pl4fr
      @MK-pl4fr 2 года назад +2

      @@uyoebyik I agree with you. I’m a long time user, and I suddenly tore ligaments and tendons.

    • @uyoebyik
      @uyoebyik 2 года назад +1

      @@MK-pl4fr benzodiazepine induced neurological dysfunction.(BIND)

  • @Methre
    @Methre 4 года назад

    „I like your skeeeechers, you like me my Gucci shoes“ 🎶 sorry, I had to 😂
    But awesome video!

  • @sudharsan458
    @sudharsan458 5 лет назад

    Super sir !

  • @muhammadkhan8094
    @muhammadkhan8094 Год назад

    nce boss

  • @umeshhadimani177
    @umeshhadimani177 Год назад

    Current year pharmacology notes bekitt ri

  • @todatmathoh3845
    @todatmathoh3845 3 года назад

    What about nitrazepam

  • @vikrantnarayan7233
    @vikrantnarayan7233 5 лет назад

    Nice

  • @truehuman9449
    @truehuman9449 5 лет назад +3

    Why medical world giving almost death hell warning for benzodipines.

  • @deepikachouhanchouhan5554
    @deepikachouhanchouhan5554 4 года назад +2

    👏👏👌👌😍😍

    • @hudsonemory7496
      @hudsonemory7496 3 года назад

      i know Im asking the wrong place but does someone know of a way to get back into an Instagram account..?
      I somehow forgot the account password. I would appreciate any assistance you can offer me!

    • @willieelian743
      @willieelian743 3 года назад

      @Hudson Emory Instablaster ;)

    • @hudsonemory7496
      @hudsonemory7496 3 года назад

      @Willie Elian Thanks for your reply. I found the site thru google and Im trying it out atm.
      Seems to take a while so I will get back to you later when my account password hopefully is recovered.

    • @hudsonemory7496
      @hudsonemory7496 3 года назад

      @Willie Elian It did the trick and I now got access to my account again. I am so happy:D
      Thanks so much you saved my account!

    • @willieelian743
      @willieelian743 3 года назад

      @Hudson Emory happy to help xD

  • @imalokhan7295
    @imalokhan7295 4 года назад

    Ibs Parr aik video

  • @vkzone8812
    @vkzone8812 3 года назад

    Etizolam kon sir class me h

  • @amareshpawar2432
    @amareshpawar2432 3 года назад

    If 100 tablet takes diazepam what happened

  • @amareshpawar2432
    @amareshpawar2432 3 года назад

    Anyone know this answer tell ...the a I'll tell

  • @asserm.8047
    @asserm.8047 4 года назад +2

    it seems like you made this video with the thought process of "ok lets answer all of their exam questions" lmfao

  • @rohittiwari4988
    @rohittiwari4988 5 лет назад +2

    Which kind of person use Benzodiazepine

  • @Sinhadoc
    @Sinhadoc 3 года назад

    Thora hindi m v bol liya kijiye...samjh nhi aata h bahut bAAt ..explain to Kiya kijiye

  • @ramprasadpokhrel9895
    @ramprasadpokhrel9895 3 года назад

    I'm taking Clobazam since 1 and half year. And later added Divalproex but my seizure never controlled and quit the divalproex and now taking Lacosamide with Clobazam but still my seizure hasn't stopped. My diagnosis was calciofied granuloma related to neurocysticercosis and left mesial temporal sclerosis. Now lost of hope my seizure will control with any kind of medicines. Only increasing dependency of benzo medicine. Now want to quit medicine.