"What is Apoptosis?" The Apoptotic Pathways and the Caspase Cascade
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- Опубликовано: 17 окт 2016
- This 3D medical animation explains the functioning of the extrinsic and intrinsic apoptotic pathways. We start off by taking a look at the important role apoptosis plays in growth and development as well as removing DNA damaged cells. Then we see how activation of the caspase cascade occurs in each external and internal signalling pathway. Lastly we get a glimpse of cancer cells and their ability to block apoptosis.
© Elvire Thouvenot-Nitzan, 2016
www.elvirethouvenot.com
This resource is shared under Attribution-NonCommercial-NoDerivatives Creative Commons license (CC-BY-NC-ND 4.0). You are free to copy and reuse this for non-commercial purposes but we ask that you acknowledge “Elvire Thouvenot-Nitzan, created in collaboration with University of Dundee” when doing so. If you remix or modify this material, you may not distribute the modified material.
Medical Animator
Elvire Thouvenot-Nitzan BSc, MSc
Centre for Anatomy and Human Identification, University of Dundee
Medical Advisor and Pathology Instructor
Richard Oparka MBChB, FRCPath
Department of Histopathology, University of Dundee School of Medicine
MSc Medical Art Advisor
Caroline Erolin BA(Hons), PGCert, MPhil
Centre for Anatomy and Human Identification, University of Dundee
Technical Advisor
Annie Campbell BSc, MSc
Technology & Innovation Learning Team, University of Dundee School of Medicine
Attributions:
This animation features the track “Enrichment” by Podington Bear. The track is licensed under CC BY-NC 3.0 and has been edited to fit the animated short.
freemusicarchive.org/music/Podington_Bear/Backbeat/Enrichment
The animation features sound effects from freesfx.co.uk.
How about a round of applause for the people made this?
How about a round of applause for the Who created this creativity?😊
Oh yes definitely 👏👏👏👏👏👏
Definitely. Kudos to people who made this.
Sir yess sir!!
I really liked the Fazballs and Fazbeans
i LOVE that clicking noise when caspases activate one another 1:50
SATISFYING
same im triggered
Haha same
😂😂yes
Right with all those sounds I get the whole process. I love this video.
this was oddly very soothing to watch
George Partington I KNOW omg so relaxing
Yaaaaah, I am truly influenced by the greatness of the Creator 🙆♀️
You made apoptosis so cute ! The bubbles and the popping sounds Are 💘
Love U 💞🤩
the best video on apoptosis ever seen
True
Are you from china
This is by far one of the best biochemistry videos I've ever seen! :) Literally didn't wanted it to end!
pretty sure this is the cutest, most satisfying and relaxing biochemistry video ive ever seen
Whoever animated this deserves a Nobel Prize and a contract with every school in the world
This is one the best biology videos I've ever seen. Highly appreciated. Thankyou.
still one of the best biology videos I've ever seen, and graphics have only gotten better since five years ago:')
Yes, round of applause. Excellent animation and animation.
Very easy to remember the difference between intrinsic and extrinsic after seeing this animation, thank you!
I really want more of this ....
This is evolutionary ✨✨
Respect and love for all who made this !
It's absolutely peaceful and amazing ❤️❤️❤️❤️❤️❤️❤️❤️
ASMR: The educational version
This video is amazing!! Great animations, sound effects, a clear script which is basic enough to follow along, and a great narrator! Well done
I kept smiling while watching this video. It's so well-made! Thanks so much!
Same here chootye am also like this vodeo
You're gonna love apoptosis after watching this
This turned my frown upside down, thanks! I gleefully bobbed my head up and down as I made notes and consolidated my understanding after stumbling through pages upon pages of module text!
i usually don't like to comment in youtube videos but after watching this i think you deserve a thank you from my heart one of the best videos in medical field that i have ever seen
Thank you so much for sharing this with us. This video makes it so clear and easy to understand a rather complex concept. Respect to the people who made this!
There is no better way to describe the process! Splendid animation!
This is awesome!!!! I, have never seen a more simplified yet conscised explanation of Apoptosis. My standing ovation🙌🙌🙌
This the best video I’ve ever seen in my entire life! 1 hour lecture about apoptosis and not a single thing in my brain. But this!!!!!
This was helpful thank you. Strangely it was really satisfying too! The noises of the cascade and fas ligand binding where particularly satisfying. Great job.
This has totally chilled me out during extreme exam stress - thank you!
This is the most adorable explanation of apoptosis.
one of the most explicit and simple to understand videos
Awesome! We (as in I) need more animated videos like this! This is how I learn the best.
The bestest video for apoptosis biochemical changes
beautifully explained and visually stunning
This is the best scientific video I have ever seen
The best video for apoptosis! thank you, whoever made this amazing video
This is one of the best videos I've ever seen in my life. Just wow! Thank you all so much for this remarkable creation.
Cant get better than this!
The best video on apoptosis I ever came across.
Thanks a lot!
One of the best animation video.
Thank you!
Caspases are so cool
I love the explanations, very smooth
I have never seen apoptosis made this easy. This is wonderful. Great job!!
Very good illustration and clear voice. Thank you
Wow that was so down to earth and well illustrated. nice vid!!
The animations are so satisfying to watch, and well explained!
From 2nd yr of my med school untill now in my pg prep days it's always been my 1st choice revise apoptosis.. thanx for making this incredibly concise yet high yielding vdo
This is the best video I have watched an apoptosis so far, I am learning while enjoying the music in the background, this is awesome
SUPERB . ROUND OF APPLAUSE FOR YOU GUYS.
Amazing video! Great visuals!
i can’t describe how great this is
I love this! Simple and well-explained!
Beautiful sound effects!
Love this visual approach
Best video on apoptosis ! Super easy explanation
back again and still the best on you tube
Thanks you!!!! Love that you made this understandable to the general population who lack a scientific background. Excellent video!
I loved the animation - this was so easy to understand!
This is one of the most helpful videos I've seen! The sound effect is oddly satisfying as well ;^)
Thank you! For the clear and well presented work 😍
I’m so lucky to have
this video, many thanks 💕💕💕💕
Thank you so much, now I can put it all together in my head, before I was confused by the details. :)
That was magnificant!!!
This is simply phenomenal video content!!! 🙏
thanks alot for this spectacular illustrative animation, it was very explanatory
THIS IS SO GOOD AND SOOTHING TO WATCH
i have seen many videos about apoptosis but this one is by far the best one
it was very simple and contains at the same time every thing you should know
this is the best explanation I've seen thank you so much
👏👏👏👏 Thank you so much.. I highly appreciate the efforts of makers
more of those videos ! awesome animation
Simply Amazing Guys,keep up the good work.👍😊
Thank you so much!!!!!!! this was so useful and well made
The sound of the activation of caspase cascade is relaxing.
Excellent video, thank you!
Wow, really great work.
WE NEED THIS IN OUR LIVES
Best video on apoptosis
Nicely animated
To be precise cutely done
Woww I thanked for whoever made this !!! It so easy to understand and helps a lot !!!
A great video! Thank you.
Such an awesome video.
Awesome video...excellent explanation.. Thank u so much
This is such a helpful video - thank you so much!
Very well explained. Thanks a lot
This is amazing! Thank you for this video.
What a fancy explanation! I cannot thank you enough for this great work ❤️
Congratulations for the amazing video.
Very clear. Congratulations.
nice animation, excellent explanation ! . thanks
Excellent video, this is one of the best video biology i've ever seen, Thanks you👍
how beautifully explained by making such meaningful animation. Truly impressed by seeing caspases.
Thank you for your comment! You might also enjoy some of the other University of Dundee biomedical animations available at vimeo.com/dundeetilt.
This was really helpful. THANK YOU
Wonderful explanation
the best video that i saw on apoptosis
Bro this is beautiful!
Amazing video! Thanks
what a beautiful video on apoptosis
Really good animation on apoptosis ever seen in youtube
Great man thank u ☺️😊
could not understand a single thing my teacher was talking about thank u sm for this video 🙏🏼🙏🏼
This is freaking amazing 👏🏼👏🏼👏🏼👏🏼👏🏼
I love this animation and clicking sound
You’re a genius, thanks for making this video!
thank you so much for making this it has been immensely helpful
Wow great explanation with animation
Best video ever on apoptosis
Awesome presentation
Awesome explanation