Coated Blade Spray-Tandem MS for Rapid Screening & Quantitation of Drugs in Oral Fluids

Coated Blade Spray is a sample preparation device that can be directly interfaced to mass spectrometry instrumentation for rapid screening and quantitation.
CBS is a coated stainless-steel sheet with the shape of a small sword. It has an ultrathin SPME coating that permits rapid enrichment of small molecules present in a given sample. As a result, the coating provides sample cleanup and prevents the extraction of salts and macromolecules that could cause instrument contamination.
In this poster video, we demonstrate how CBS coupled to tandem mass spectrometry enables rapid screening and quantitation of multiple controlled substances and pain management drugs in samples of oral fluids.
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