- Видео 28
- Просмотров 26 418
Journal of Investigative Dermatology (JID)
США
Добавлен 22 июн 2022
Follow our channel as we build our library of videos in the field of cutaneous biology and disease, and in particular our MTSR (Methods and Techniques for Skin Research) series' teaching videos.
JID January 2025 Cover - Illuminating Congenital Melanocytic Nevi
Skin, congenital nevus, SPTBN1, SOX10
Representative image of a large congenital melanocytic nevus stained with antibodies against SPTBN1 (purple) and SOX10 (white), a known melanocyte marker. Both epidermal melanocytes (top left corner) and dermal melanocytes (round cell clusters) are observed. Nuclei are counterstained with DAPI (blue). Scale bar = 40 µm. Video was generated using Imaris x64 9.6.0. Build 55159 for x64.
Representative image of a large congenital melanocytic nevus stained with antibodies against SPTBN1 (purple) and SOX10 (white), a known melanocyte marker. Both epidermal melanocytes (top left corner) and dermal melanocytes (round cell clusters) are observed. Nuclei are counterstained with DAPI (blue). Scale bar = 40 µm. Video was generated using Imaris x64 9.6.0. Build 55159 for x64.
Просмотров: 46
Видео
JID Dec. Heterogeneity of Fibroblast Activation States Pathophysiologically Stiff Culture Substrates
Просмотров 301Месяц назад
Myofibroblast, fibrosis, wound healing, mechanobiology, α-smooth muscle actin, Collagen type I, alpha Fibroblasts were isolated from the subcutaneous tissue of dual reporter mice expressing GFP under the control of the col1α1 promoter (green) and RFP under the control of the α-smooth muscle actin (α-SMA) promoter (red). Cells were fixed following 7 days’ culture on ‘scar-stiff’ silicone elastom...
JID November 2024 Cover - Mechanism for Bacterial Translation Inhibition by Clindamycin
Просмотров 1252 месяца назад
Clindamycin, Acne, Ribosome, Infection, Bacteria, Cryogenic electron microscopy The binding site of clindamycin in the ribosome of Cutibacterium acnes. Clindamycin inhibits peptide bond formation by interfering with the proper orientation of the aminoacyl moiety of the A-site tRNA. It binds at the beginning of the nascent peptide exit tunnel of the 50S ribosomal subunit close to the peptidyl-tr...
JID October Cover Video: Melanocyte-Keratinocyte Interactions in the Epidermis
Просмотров 1573 месяца назад
Skin, human, melanocyte, keratinocyte, dendrites, SHG, THG, dermis, epidermis, collagen The movie depicts a shallow 3D reconstruction of the dermal-epidermal interphase of a human skin section showing how melanocytes are forming dendrites into the keratinocyte layers of the epidermis. The image was acquired on a dual-laser two-photon microscope, and label-free second-harmonic and third-harmonic...
JID September 2024 Cover - Subcutaneous fibroblasts spreading for 4 days on tissue culture plastic
Просмотров 834 месяца назад
fibroblasts, fibroblast culture, myofibroblasts, F-actin, α-smooth muscle actin Fibroblasts were isolated from the subcutaneous tissue of wildtype mice. Following fixation and permeabilization cells were immunostained for the myofibroblast marker α-smooth muscle actin (α-SMA, red), intracellular and extracellular collagen I (yellow), F-actin (phalloidin, blue), and DNA (DAPI, white). Photograph...
JID July 2024 Cover: Spatial in situ transcriptome analysis of mouse skin at embryonic day 13.5
Просмотров 1236 месяцев назад
Developmental biology, Fibroblast, Single-cell analysis, Spatial analysis, and Transcriptome Expression of Crabp1 (green dot), Twist2 (yellow dot), Dlk1 (red dot), Mef2c (blue dot), Acta2 (purple dot), and Krt5 (orange dot) indicating early heterogeneity of mouse embryonic fibroblasts at embryonic day 13.5; each color-labeled dot corresponds to a specific transcript captured from a particular l...
JID June 2024 Cover: Mammary bud epithelium (TO EDIT)
Просмотров 887 месяцев назад
mammary bud, hair follicle, tissue recombination, Sox2 Mammary bud epithelium adopts hair follicle cell fate upon contact with the hair follicle dermal condensate. E13.5 mouse mammary bud epithelium expressing mGFP (cyan) was manually separated from the surrounding mammary mesenchyme after enzyme treatment, and recombined with the E16.5 back skin mesenchyme dissected from a mouse embryo ubiquit...
JID May 2024 Cover: Spotlight on Atopic Dermatitis
Просмотров 1658 месяцев назад
Atopic dermatitis, eczema, atopic hand eczema, head and neck dermatitis, scratching, scratch scars, wounds Various manifestations of atopic dermatitis in patients of different ages.
JID April 2024 Cover: Neutrophil recruitment after cutaneous injury in zebrafish
Просмотров 9729 месяцев назад
Cutaneous wound, neutrophil swarming, wound healing, zebrafish Timelapse movie of an adult Tg(lyz:DsRed2)nz50 transgenic casper mutant zebrafish with skin stained in BODIPY (white) and neutrophils in orange (lyz:dsRed) showing neutrophil recruitment 0.5 - 17.25 hours post injury. A mass influx of neutrophils is seen during the indicated time suggesting that neutrophils respond quickly to cutane...
JID March 2024:Coverage of Smooth Muscle Cells on Lymphatic Capillaries in Secondary Lymphedema Skin
Просмотров 21110 месяцев назад
March cover, lymphatic, lymphedema, smooth muscle cells Three-dimensional (3D) image depicting smooth muscle cells (red) on both dermal blood vessels and lymphatic capillaries (green) in lymphedematous human skin. The image was obtained using a confocal microscope (LSM880, Zeiss) after clearing the tissue. Sample was prepared by Nao Itai and Enkhtuul Gantumur from Shiseido Co., Ltd., MIRAI Tech...
JID February 2024 Cover: SARS-CoV-2 from Skin Lesion to Ultrastructure
Просмотров 22111 месяцев назад
COVID-19; SARS-CoV-2; Spike protein; Vasculitis; Immunofluorescence; Electron microscopy; Dermatology Overview of SARS-CoV-2-Related Vasculitic Skin Lesions: A comprehensive journey from clinical images to ultrastructure. Dermal vascular cell destruction is evident in H&E staining, while electron microscopy reveals the presence of autophagosomes. Immunofluorescence images showcase spike protein...
JID January 2024 Cover: Radiological Findings in GNAQ/GNA11 Mosaicism
Просмотров 662Год назад
GNAQ/GNA11 mosaicism; Sturge-Weber syndrome; leptomeningeal angiomatosis; vascular disease T1-weighted (axial) and FLAIR (coronal) post contrast images of a patient with Sturge-Weber syndrome showing extensive pial angiomatosis. Note: status post left functional hemispherectomy
JID September 2023 Cover: Three-Dimensional Reconstruction of Mouse Skin in Early Catagen
Просмотров 173Год назад
JID September 2023 Cover: Three-Dimensional Reconstruction of Mouse Skin in Early Catagen
JID July 2023 Cover: Secretion of Epidermal Lamellar Granules Revealed by 3D Electron Microscopy
Просмотров 263Год назад
JID July 2023 Cover: Secretion of Epidermal Lamellar Granules Revealed by 3D Electron Microscopy
JID June 2023 Cover: 3D Reconstruction of Desmoglein-1 in Adult Human Epidermis
Просмотров 97Год назад
JID June 2023 Cover: 3D Reconstruction of Desmoglein-1 in Adult Human Epidermis
JID April 2023 Cover: Vimentin+ Cells and Extracellular Matrix in Human Dermis
Просмотров 129Год назад
JID April 2023 Cover: Vimentin Cells and Extracellular Matrix in Human Dermis
JID March 2023 Cover: 3D Image of Human Keratinocytes in Tissue Culture
Просмотров 84Год назад
JID March 2023 Cover: 3D Image of Human Keratinocytes in Tissue Culture
JID February 2023 Cover: Spotlight on Skin Nerves
Просмотров 130Год назад
JID February 2023 Cover: Spotlight on Skin Nerves
JID January 2023 Cover: Spotlight on Epidermal Langerhans Cells
Просмотров 1322 года назад
JID January 2023 Cover: Spotlight on Epidermal Langerhans Cells
Pharmacoepidemiology Research Methods in Dermatology
Просмотров 2922 года назад
Pharmacoepidemiology Research Methods in Dermatology
Emerging Imaging Technologies for Noninvasive Optical Biopsy of Human Skin
Просмотров 1452 года назад
Emerging Imaging Technologies for Noninvasive Optical Biopsy of Human Skin
Great
EXCELLENT!
beautiful!
awesome
Excellent summary! Nicely done
This is amazing. I want to know how this video was made
Thank you!!! Especially for the comparisons of techniques❣️
great ! Thank you
멋집니다
magnificent!