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Maria Conley MD
Добавлен 19 мар 2019
I am a board certified internal medicine physician and I have been practicing medicine for 15 years. My mission is to provide current and evidence-based medical information in plain language.
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Medical Disclaimer: The content of this RUclips channel is solely for informational purposes and not a substitute for professional medical advice. Consult a healthcare provider for medical concerns, and in emergencies, contact your physician or 911. The material on this RUclips channel is intended for the general public and is not specific medical advice. Views are mine and do not represent those of my employer.
Dispute Resolution: By accessing this RUclips channel, you agree that any dispute related to this RUclips channel falls under the exclusive jurisdiction of California courts. These terms are governed by California’s laws, and the invalidity of one provision won’t affect the validity of the remaining terms. No waiver implies a continuous waiver of any term or condition.
Legal Stuff
Medical Disclaimer: The content of this RUclips channel is solely for informational purposes and not a substitute for professional medical advice. Consult a healthcare provider for medical concerns, and in emergencies, contact your physician or 911. The material on this RUclips channel is intended for the general public and is not specific medical advice. Views are mine and do not represent those of my employer.
Dispute Resolution: By accessing this RUclips channel, you agree that any dispute related to this RUclips channel falls under the exclusive jurisdiction of California courts. These terms are governed by California’s laws, and the invalidity of one provision won’t affect the validity of the remaining terms. No waiver implies a continuous waiver of any term or condition.
Where You Store Your Fat Matters
A board-certified internal medicine physician discusses why it's not just HOW much fat you have but WHERE it is stored in your body. Fat stored inside the abdomen (visceral fat) is more likely to cause diabetes than fat stored just underneath the skin (subcutaneous fat). Your age, sex and ethnicity determine where your fat will be stored.
Просмотров: 231
Видео
How Severe Aortic Stenosis Causes Heart Failure
Просмотров 89Месяц назад
A board-certified internal medicine physician describes how a severely tight aortic valve (severe aortic stenosis) can cause heart failure if it is not replaced in time. Aortic stenosis is the most common problem affecting heart valves, occurring in about 3% of all people over age 75. Once you have been diagnosed with mild aortic stenosis, the valve inevitably gets tighter over time and a new v...
Aortic Stenosis: When Your Oxygen Delivery Valve Fails
Просмотров 1383 месяца назад
A board-certified internal medicine physician discusses calcific aortic stenosis (tightening of the aortic valve), how it develops and why it is a problem. This is a common heart valve disease, especially if you are over 75. A tight aortic valve can cause trouble breathing or chest pain because your body may not be able to get enough oxygenated blood. A working aortic valve is critical to deliv...
How Much Alcohol Can I Drink Safely? The Calculated Risk of Drinking a Toxin and Carcinogen
Просмотров 1295 месяцев назад
A board-certified internal medicine physician discusses how alcohol intake can be considered as a calculated risk. Alcohol (technically ethanol) is the most common toxin and carcinogen that humans drink voluntarily. A potential benefit is the short-term upregulation of endorphins, GABA and serotonin, potentially causing feelings of relaxation and sociability. On the flip side, drinking any amou...
Muscle Regeneration After Injury: How the Satellite Cell Builds New Muscle
Просмотров 3876 месяцев назад
A board-certified internal medicine physician explains how skeletal muscle is able to repair itself after exercise. One of the primary orchestrators of this process is the satellite cell, otherwise known as the adult stem cell of muscle. The ability of skeletal muscle to regenerate makes it possible to build new muscle at ANY age.
Adult Hippocampal Neurogenesis Explained in 3 Minutes
Просмотров 9358 месяцев назад
You are able to grow new brain cells throughout your life in the hippocampal formation of your brain. Certain activities such as running and learning new things can trigger this process. We'll follow a newborn neuron (brain cell) from its creation at Day 1 to the time it becomes a mature neuron at Day 60. Explained by a practicing board certified internal medicine physician.
Hitting the Triple G Spot: The New Triple G Agonist for Weight Loss
Просмотров 1,6 тыс.8 месяцев назад
A practicing internal medicine physician talks about the new "G receptor" agonist weight loss medications semaglutide (Ozempic, Wegovy), tirzepatide (Mounjaro) and the latest drug in the pipeline retatrutide. We'll see how retatrutide, a so-called "triple G agonist" may be the most effective weight loss medication of all. By adding the combined hormonal effects of GLP-1, GIP and glucagon, retat...
How Running Slows the Aging of Your Brain
Просмотров 51210 месяцев назад
A practicing internal medicine physician talks about how running slows the age-related shrinkage of the hippocampus, an area of your brain critical for memory. We will also see how brain-derived neurotrophic factor (BDNF) catalyzes the formation of new neurons and synapses.
Running Makes Your Brain Work Better: The Role of Neurotrophic Factors
Просмотров 71011 месяцев назад
A board-certified internal medicine physician discusses how proteins called neurotrophic factors affect how your brain functions. We'll see how the most famous neurotrophic factor BDNF (brain-derived neurotrophic factor) is upregulated during running. Ultimately, running throughout your life can help preserve and enhance cognitive function and BDNF is one mechanism behind this benefit.
GLP-1: The Weight Loss Molecule
Просмотров 3,4 тыс.Год назад
A board certified internal medicine physician explains how two of the most effective weight loss strategies today the medication semaglutide (Ozempic) and weight loss surgery work by increasing the level of GLP-1 in your body. GLP-1 travels in your gut-brain axis via your bloodstream or by activating your vagus nerve. It works as a hormone and as a neuromodulator to change the way you think abo...
Adult Hippocampal Neurogenesis: Growing New Brain Cells as an Adult
Просмотров 9 тыс.Год назад
A board certified internal medicine physician talks about how your adult brain creates new brain cells in a process called adult hippocampal neurogenesis. Certain activities such as running and learning a difficult task can trigger even more neurons to be created.
Hippocampus, the Seahorse in your Brain: Where Neurons are Born
Просмотров 553Год назад
A board certified internal medicine physician talks about the hippocampus (Latin for "seahorse"). This is a small area of your brain that is critical for forming new memories. It shrinks with age and is the first brain structure affected by Alzheimer's dementia. It is also the only place in the human brain where new brain cells (neurons) are born throughout life, even as an adult.
The Highs and Lows of Animal Blood Pressures: Cuttlefish, Giraffe & Human
Просмотров 414Год назад
A board certified internal medicine physician reveals one way that you resemble a cuttlefish: you both have a closed blood circulation system. We will look at why blood pressure varies so much from the very low pressures of aquatic animals like cuttlefish to the much higher pressures of land dwelling animals who must also push blood against the force of gravity. We'll also examine the extreme p...
How Do Age and Exercise Affect My Metabolic Rate?
Просмотров 634Год назад
A board certified internal medicine physician talks about your basal metabolic rate as just one component of your total daily energy expenditure (TDEE). At what age does your metabolic rate begin to slow down? Does increasing your level of physical activity increase your metabolic rate? What can you actually DO to ramp up your metabolism?
What Happens to Fat When You Lose Weight?
Просмотров 1,8 тыс.Год назад
A board certified internal medicine physician talks about where your fat goes when you lose weight. Contrary to popular belief, it is not turned into energy or muscle. You actually exhale most of the fat as carbon dioxide while the remaining amount is lost as water. Weight loss only occurs when atoms (carbon most notably) leave your body.
Increase Your Stroke Volume to Improve Your Exercise Performance
Просмотров 2 тыс.Год назад
Increase Your Stroke Volume to Improve Your Exercise Performance
Achieving Your Highest Lifetime Peak VO2max: What Will Your VO2max Curve Look Like?
Просмотров 295Год назад
Achieving Your Highest Lifetime Peak VO2max: What Will Your VO2max Curve Look Like?
How Powerful is Your Engine? A Look at VO2max
Просмотров 587Год назад
How Powerful is Your Engine? A Look at VO2max
The Genetically Programmed Diet of Homo sapiens
Просмотров 4,9 тыс.Год назад
The Genetically Programmed Diet of Homo sapiens
The State of My Metabolic Machine: The 3 Most Important Numbers to Know
Просмотров 6162 года назад
The State of My Metabolic Machine: The 3 Most Important Numbers to Know
Seeing a Moonbow: Your Eyes vs. a Camera
Просмотров 1532 года назад
Seeing a Moonbow: Your Eyes vs. a Camera
The Silent Epidemic of Fatty Liver Disease
Просмотров 1,1 тыс.2 года назад
The Silent Epidemic of Fatty Liver Disease
Optimizing Bike Fit to Prevent Injury
Просмотров 5052 года назад
Optimizing Bike Fit to Prevent Injury
Cycling to Maintain Muscle Mass: A Tour Around the Crank Cycle
Просмотров 6 тыс.2 года назад
Cycling to Maintain Muscle Mass: A Tour Around the Crank Cycle
Contract Your Muscles and Activate Your Myokines: Focus on IL-6
Просмотров 7 тыс.2 года назад
Contract Your Muscles and Activate Your Myokines: Focus on IL-6
How French Fries Can Explain Sugar Toxicity in the Body: The Maillard Reaction in Diabetes and Agin
Просмотров 1,5 тыс.2 года назад
How French Fries Can Explain Sugar Toxicity in the Body: The Maillard Reaction in Diabetes and Agin
thanks!
Thank you! That was the best explanation I have watched on GLP-1.
Appreciate the detailed yet user-friendly explanations and illustrations!
what about for post gall bladder removal surgery diarreah? how to take?
Thank you so much!
1 thing tho the more stuff you add the harder it is when you come off.. Stay with semaglutide and try to use lowest effective dose possible and diet only for 6-8 months then start slowly eating more to increase metabolism then when recomped for few months then diet again that's how you get a nice body and health body If diet for too long its going to kill you're metabolism and you won't lose fat only muscle
Anything other than Mounjaro for GIP?
This is interesting. I like to take an integrative proactive approach. I guess it works for many people, weight can be a problem.
🎉😍TYVM
Hi! Thank you for translating science for regular people. I feel I learn a lot.
Excellent video. Thank you!
This is how educational videos should be made... take notes NASA... clear animation with easy to follow nomenclature.
Does a locked in syndrome patient grows new neurons ?
I'm crying
The best explanation
So would that mean that, people who do deep breathing or mediation along with diet/exercise can lose more weight?
I wish!
Learning how to walk. Sorry. Typing with one hand.
Can any aerobic exercise work? I sustained a severe traumatic brain injury. Learning how to work. Nowhere near running yet. Walking is a challenge. Great video. Keep them coming. Blessings,
Thanks a lot
Great info
What’s a good mileage to run daily? I run 3 miles daily but I feel like it may not be enough for capillary density.
it was helpful, thank you
By the way, walking is as good as running. Just some kind of activity that is sustained aerobics. I was in an accident and in a COMA several weeks. Upon recovery I was told the best thing I could do is walk walk walk and walk some more.
Very helpful ❤
that was great, thanks so much
Good
Thank you for breaking down, in understandable terms, the importantance of exercise via Myokines. So important for folks to know the mechanism that make such positive changes throughout the body. It makes it real. Would like to see you do the others IL-15, Irisin etc. As a Senior Fitness Traniner/Specialist this info really helps...
nice work! I'd say that barbell squats would be good for IL-6
Great explanation! #KickAss100YrOld
This was a wonderful explanation and the graphcis really helped emphasize the pooints. Thanks for putting this together
Thank you for your explanation
All the information I need from this video is in the first 36 seconds and that's before you even said Hi.
Yep.
This is incredibly useful information. You are incredibly talented presenter.
Dear Maria, your VO2 explanation is so concise and elegant. Listened to Attia go on for for hours, and did not get much. And they we say women bubble too much hahaha.
Glad to find this video which makes such a difficult topic to be so enjoyable! Thanks!
Wow!!!
I had no Idea!
A couple questions: When I eat more carbohydrate than I use immediately, isn't it stored not as fat, but as glycogen? What happens when I eat more fat than my body can use as fuel? Is some of that fat stored in my body, and is any deposited in the wrong places, such as inside the arterial walls, as visceral fat in the abdomen, or in organs such as liver, muscle, heart, and pancreas? Which is most easily converted to or deposited as body fat--carbohydrate excess or fat excess?
The benefits of running are remarkable. I'm gonna start tomorrow!
TY
You explain everything so clearly! I am now finally coming to unerstand really how the metabolism actually works. Thank you!
Thank you so much doctor
Great and detailed explanation!
The summary is runners have better brains. If you don't run. Then, keep learning difficult information and do difficult mental tasks, thinking, research, etc.
Thank you!
Thanks for this. I can't run coz of medical reasons.
Doctor im really interested in your work i been going through my life with really high cortisol levels and I think my hippocampus has shrunk because my memory loss is horrible but I would like to get my masters on this subject because its so interesting for me and wish you would supervise me because i love your work
Thank you for posting this very interesting video. You refer to one particular form of aerobic exercise - running - in this and previous videos. Does any form of 'aerobic' exercise (that which pushes the HR into the 'aerobic zone' ( == 70% - 80% of HR-max)) have the same effect (e.g. 'aerobic' levels of cycling, rowing, etc.) ?
Pus filled scabs don't form on my skin without some kind of injury, burn, abrasion, or infection. LDL doesn't cause heart disease. Injury causes heart disease. LDL is part of the damage repair.
Plain explanation and to the point...