mRNA Processing in Eukaryotes - Capping, Splicing, Polyadenylation | Pnkj Verma Sir

In molecular biology, messenger RNA (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene and is read by a ribosome in the process of synthesizing a protein.
Transcription is when RNA is made from DNA. During transcription, RNA polymerase makes a copy of a gene from the DNA to mRNA as needed. This process is slightly differs in eukaryotes and prokaryotes. One notable difference, however, is that prokaryotic RNA polymerase associates with DNA-processing enzymes during transcription so that processing can proceed during transcription. Therefore, this causes the new mRNA strand to become double stranded by producing a complementary strand strand know as the tRNA strand. Furthermore the RNA is unable to form structures from base-pairing. Moreover, the template for mRNA is the complementary strand of tRNA, which is identical in sequence to the anticodon sequence that the DNA binds to. The short-lived, unprocessed or partially processed product is termed precursor mRNA, or pre-mRNA; once completely processed, it is termed mature mRNA.
mRNA is created during the process of transcription, where an enzyme (RNA polymerase) converts the gene into primary transcript mRNA (also known as pre-mRNA). This pre-mRNA usually still contains introns, regions that will not go on to code for the final amino acid sequence. These are removed in the process of RNA splicing, leaving only exons, regions that will encode the protein. This exon sequence constitutes mature mRNA. Mature mRNA is then read by the ribosome, and, utilising amino acids carried by transfer RNA(tRNA), the ribosome creates the protein. This process is known as translation. All of these processes form part of the central dogma of molecular biology, which describes the flow of genetic information in a biological system.
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[@nextgeneration7925]

Very Simply Language explanation 💓🥰👌

[@anitaprajapat8480]

Thank you so much......bhut badi help ki h aap ne 🙏🙏🙏

[@BiomaniaBiologyClasses]

God bless you beta

[@barshabiswas5646]

After lots of struggle...finally can understand

[@NibeditaMoharana-kh9py]

Thank you sir This video lectures are very very helpful for me❤

[@ashwinimurthy8733]

Sir capping explanation was bang on 👌🏼... Tnk u

[@BiomaniaBiologyClasses]

wlcm ☺️ dear

[@suchismitasahoo6384]

After lot of struggle I found this video it is very helpful.......Thank you so much sir for explaining it very simple language 😊

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That was so easy to understand thank you sir

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after seen many videos i hold here what a explanation

[@sawanpandey01]

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You made it more esier

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Your way of teaching is very good👍 you make the things very simple for understanding 👍

[@1indrani-]

Nicely said... thank you

[@manishamohil6833]

Thankyou sir you made the concepts clear☺

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Thnk u so much sir ❤ aap na mare badi problem solve kardi thnk u so muchhhhhhhhhh

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[@SumitChhimpa]

Thank you Sir.. 😊😊

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Thank you so much too u infact for such a simple+ easy lecture 👏👏👏👏

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Very simple explanation Thank you so much sir😊

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Thanks vermaa ji ❤️❤️❤️

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Awesome explaination sir

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Thank you so much sir

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Great 😍

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Way of teaching is super❤

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Thanks sirr you made the concept clear 😊

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Thanks sir ji ❤️

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Thank you so much you teach very easy method

[@rinkychoudhary1132]

Sir yh termination vlaa kya hh ab n2 bas ya nucleotide

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You make every step so much easier with great explaination .... thank you sir👍☺️

[@BiomaniaBiologyClasses]

thnx dear Ankit🤗

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Thank you bhaiya

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Thank you soo much sir❤️

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You are amazing sir thanks a lot

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Thank you so much sir ...

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You are great teacher, thanks you so much sir 😊😊😊..

[@sehrishnoor6505]

Thank you this vedio made my concept clear

[@shubhangimose6761]

Thank u sir very nice explaination 😊❤

[@jebinanjum3661]

Thank you ❤❤

[@komalmeena_2003]

Perfect explanation 🥰

[@aradhanapandeydance5655]

Thank you sir

[@ayeshafarhad1575]

or best video hy ,bht try ki thi me n but smjh ni a re thi ab agayi thanks a lot

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Thank you🙏 sir

[@15ritika95]

Thankuu sir🌼

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Sir how do u record... I mean how do u set camera

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U help me a lot 🥰

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Great sir

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👍👍👍 THANK YOU SIR

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Good concept

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Thnku sir🙏

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Very good explanation, appreciate your knowledge and skill

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Helpful for neet ug

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Thankyou sir

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Bhai best videoo..

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Thank you so much sir helpful vidio tha

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Wah yar thanks

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Thanku sir very easy mathed to understand lectuer

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Tq bhaiya

[@nishakumawat7388]

Wow sir kya ..smjate ho ..aap ..hme .. almost classes me ye ni btaya jata h ki...post translation kha h ..kis jgh se strat horha h..aapka video bohot helpful hota h...tnx u .sir.. God bless you 👍👍

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Wlcm Nisha beta

[@SumitChhimpa]

But aap pen & stic ki cap utar kar rakha karo..

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Nice explanation sir

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Khup बेसिक पासून start karun छान expain केले आहे

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Thenks sir

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Superbbbb

[@masterofzoology7010]

Sir, tRNA Cell mai Khan pe banta hi

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👌🥰

[@aliafaizan8512]

Is it RNA processing or mRNA processing is same

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Tq sir very easily axplain

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❤️👌

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[@UniqueStudyIdea]

sir ye prokaryotic and eukaryotic m same hai ya different

[@BiomaniaBiologyClasses]

prokaryotes me kbhi capping tailing ya splicing nhi hoti dear,,,,kyuki unme introns nhi hote,,,or wo mature hi bnte h,,
ye sb sirf eukaryotes me hi hota h.

[@simaranchoudhary1229]

Mst

[@archanadas1795]

Capping is bit confusing

[@kundanrajput3368]

Iska pdf nhi milega ky

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Sry dear,,,i don't have,,,many of my notes has been lost

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Please Shabdo ko thoda Bada likhe sir

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1st subscriber then 1s visit

[@ayeshafarhad1575]

sir is capping ki to smjh ni ayi😭

[@ashwinimurthy8733]

Phirse deklijiye ise simplified explanation kahi pe b nahi milegi 🙏🏽

[@aachalhadke2483]

Thank you so much sir

[@sehrishnoor6505]

Thank you this vedio made my concept clear

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Thanks sir

[@Chandrabhanbind730]

Thank you sir