GOUT Under the Microscope: Brilliant Polarizable Birefringent Monosodium Urate Crystals

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  • Опубликовано: 1 янв 2025

Комментарии • 44

  • @JMGardnerMD
    @JMGardnerMD  3 года назад +1

    A complete organized library of all my videos, digital slides, pics, & sample pathology reports is available here: kikoxp.com/posts/5084 (dermpath) & kikoxp.com/posts/5083 (bone/soft tissue sarcoma pathology).

  • @thelongboat831
    @thelongboat831 8 месяцев назад +5

    this kept me up for days. watching what i eat from now on

  • @hshwang-h5f
    @hshwang-h5f 2 месяца назад +1

    Four years ago, I tried to find urate crystals in H&E stain, and now I realize that it was a futile effort. Thank you, Dr. Gardner!

  • @itsmesanto
    @itsmesanto 3 года назад +22

    The worst thing about Gout is it just happens so randomly and keeps you crawling on the floor and constant pain for days at a time.

    • @jenandjuice7475
      @jenandjuice7475 2 года назад +4

      I was just diagnosed with this yesterday but the last three days I’ve been begging someone to just go ahead and cut my foot off the pain was unreal😢

    • @Dexter-wb6kb
      @Dexter-wb6kb Год назад

      Do you have gout on your big toe?

    • @Dexter-wb6kb
      @Dexter-wb6kb Год назад +2

      @@jenandjuice7475 ouch! On the big toe?

    • @MrLovzz
      @MrLovzz Год назад

      ​@@jenandjuice7475the pain is still unbearable

    • @revvv3889
      @revvv3889 Год назад +2

      ​@@jenandjuice7475 I am having a flare right now... and that cursed toe bumped a door frame, the pain felt like a torture

  • @alphaomega5923
    @alphaomega5923 2 года назад +2

    Thank you so much Dr. Gardner. I have been diagnosed with gout last Friday. I tell you, it is not an easy feeling; it's very painful. It happens at my left foot right underneath the big toe. The area begins to turn red and blueish spot like and warm to the touch. I am now on Prednisone for the inflammation. It is getting better after 2 weeks. Thank you for the microscopic image into this gout illness. Blessed you Sir.

  • @TheBenzer9
    @TheBenzer9 3 года назад +18

    The pain is absolutely horrendous..please don't get gout lol

    • @Dexter-wb6kb
      @Dexter-wb6kb Год назад

      Ouch! Do you have gout on your big toe?

    • @TheBenzer9
      @TheBenzer9 Год назад

      @@Dexter-wb6kb no iv had it before its unbelievable the pain..you can control it through medication and diet..its probably the worst pain around

  • @flaschnerbiz
    @flaschnerbiz 2 года назад +4

    Dr. G! Thank you for this. I’m newly diagnosed and this is very educational.

  • @medlawmlb
    @medlawmlb 3 года назад +4

    Very valuable and very well-done. Thank you!

  • @منيرةالعنزي-ج7و
    @منيرةالعنزي-ج7و 2 года назад +1

    What a Great explantion and images. Thank you !!

  • @comelonneitor
    @comelonneitor Год назад

    just making a presentation about bout and omg this was so helpfull its such an improve from what books explain an even articles, its almost like a class but with the diference that i can repeat it as many times i want an in hd

  • @the_histo_guy
    @the_histo_guy 3 года назад +1

    How can we differentiate between gout and pseudogout microscopically?

  • @iniohos2
    @iniohos2 Год назад

    3:43 Ouch!! It hurt me! Not only I can see it (it's crystal😊-clear), I can feel it too!

  • @mohammadrayyan7851
    @mohammadrayyan7851 2 года назад

    This was extremely useful, plenty of thanks Dr.Jerad

  • @kasimirb5155
    @kasimirb5155 Год назад

    So, what is the bigger problem for the joint: the crystals, which "just" hurt", or the immune reaction to them, which might destroy more than only the foreign material?

  • @danielcastilo1840
    @danielcastilo1840 5 месяцев назад

    Great video doc, you made Gout come alive literallly . Thanks for taking the time to explain woth detail everything

  • @nathanOyok
    @nathanOyok 2 года назад +1

    I cried

  • @VidarrKerr
    @VidarrKerr 5 месяцев назад

    "...Pretty cool huh. For as pretty as this is, it's very painful..."
    Painful is when you hit your thumb with a hammer, or fall off a bike. These crystals send you to another dimension, where painful is like heaven.

  • @haroldchuitcheu3207
    @haroldchuitcheu3207 2 года назад

    Thanks. This is pretty instructive.

  • @jenandjuice7475
    @jenandjuice7475 2 года назад

    Some of the worst pain I’ve been in and I have three Children! Why is it that it’s worse at night? 🤷🏼‍♀️

  • @joselesanroman
    @joselesanroman 3 года назад +1

    Thanks for the very educational video. Can you take a swab sample from a tophi discharge from an ulcer or does the sample need to be in synovial fluid form (arthrocentesis)? Thank you in advance!

    • @JMGardnerMD
      @JMGardnerMD  3 года назад +3

      Drainage from a tophus might work, depending on if the discharge actually contains crystals versus just being serous exudate related to the ulcer. I think a wooden spatula/tongue depressor or something plastic might work better than a swab for getting the material on to a slide. My favorite method for excised tophus to cut it in half and then touch the glass slide directly to the cut surface of the tophus. Obviously that only works if part of the tophus has been removed surgically.

  • @markbastow3426
    @markbastow3426 Год назад

    very painful, big toe and knee is where it gets me

  • @ml9633
    @ml9633 2 года назад +1

    Both my feet big toe sides are about 3/4 inch out right now and meds do nothing to help. As for all the diet stuff, I'm vegan... dring Zero alcohol or soft drinks, avoid all sugars... and pain is atrocious. Can't even wear shoes, when i need to wear them i wrap my feet in gauze and hope for the best. Help, yes i need it bad. So, so sad... by the way, excellent video.

  • @carolinemansfield1967
    @carolinemansfield1967 2 года назад

    What magnification are you using please?

    • @JMGardnerMD
      @JMGardnerMD  2 года назад +2

      I am showing magnifications ranging from 20x to 200x in this video.

  • @mdshahedkhandokar9549
    @mdshahedkhandokar9549 3 года назад

    Thank you so much for this video.
    Best of luck 💐🌹🥀

  • @loreleifajardo2430
    @loreleifajardo2430 2 года назад

    How to dissolve?

    • @antoniocavalli5474
      @antoniocavalli5474 6 месяцев назад

      lower your UA levels in blood, either lifestyle changes or midicine

  • @mrcoolcanon
    @mrcoolcanon 3 года назад +1

    Nice 👍

  • @letsfilipino
    @letsfilipino 3 года назад

    An episode of Chicago Med brought me here. 😬

  • @Baniaigbe
    @Baniaigbe 6 месяцев назад

    Please check ur kidney function if you have gout. Gout inflammation is the worst pain ever 😢

  • @CassieSmart365
    @CassieSmart365 2 года назад

    Jesus take the wheel! GOOD LORD! I cannot even imagine all of this craziness!

  • @partymoodxv8623
    @partymoodxv8623 3 года назад

    👏🏻👏🏻👏🏻👏🏻