Inside ALS: The neurons behind the disease
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- Опубликовано: 20 апр 2017
- Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that mainly affects the nerve cells (neurons), which control muscle movement. As the motor neurons degenerate, they stop sending signals to the muscles, causing progressive muscle weakness and - ultimately - death. This animation focuses on the mechanisms within the motor neurons that cause them to degenerate. By understanding these mechanisms, researchers hope to one day find a cure for ALS.
To learn more about ALS, check out the Primer: www.nature.com/articles/nrdp2...
and the PrimeView: www.nature.com/articles/nrdp2...
Nature Research has full responsibility for all editorial content, including Nature Video content. This content is editorially independent of sponsors. 
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![Amyotrophic Lateral Sclerosis [ALS] | Mechanism of Neuron Death](/img/1.gif)
My mom have this ALS since 2007 to present. the doctor said before she's only got 3years and luckily she's with us until now. 12years since then and i hope more and more years to come for my mother :'(
God bless her stay strong ❤
Always Pray for your mother everyday ❤️
Great news! What treatment is she on?
@@ln3165 no treatment. just multivitamins. we are poor so no special equipment and no regular doctor to check her up. god bless all
@@AdventureDaksExplores where are you from? You should check and localize ALS centers in your area. May God help you and keep your mom healthy and alive.
This is literally the best channel I've ever come across on RUclips. The amount of detail and the visual complements are just incredible.
This is so informative... And reminds us being actually functioning and normal is a gift😭
I lost my nana, 3 years ago. I’m proud of who my nana was and i strive to carry on how she stayed positive threw 12 years of als. I will always love u
- ur pixie
I'm so sorry for your loss. Sounds like she was a lovely, determined and positive person. This world needs more people like your nana.
My mother was diagnosed with ALS about 2yrs ago. Watching her suffer is the hardest part. Through each stage everything gets harder and harder and it hurts k owing that theres nothing you can do but watching them die slowly. 💔
I need help
@@travelalonefiona7904 reach Dr Agbi on dragbi20@gmail.com for your healing
No there will be a cure sooon by CRISPR cas9 ... gene editing will correct the mutation that contribute to Als they're working hard on it soon 2 or 3 years it will be offer to people ... I saw it ....
I'm going trough same thing right now 😢😢
i hate this disease so much. Its SO sad, for the person who suffers is and to the people who loves them. Its literally a torture, it makes me so mad
All I know is that Mitochondria is the power house of the cell
🤣🤣🤣🤣
😂😂😂
Thank you this is literally the world's best animated and explained video ever I wish you and the creators of this video everlasting health and happiness may your families and grandchildren live long fulfilling lives because you deserve the world and nothing less. I love you.
Thanks to the person doing the voiceover and for the entire team behind the video!
This disease is so complex, I understand why they are battling to find a cure or a treatment. Good concise summary.
THIS IS SO HELPFUL
The amount of detail, smooth animation and information makes this very helpful for this school project i am doing on MND/ALS
this shit killed my grandma it was the most saddest death i've ever seen. I loved her so much.
I m just 20 and devastated
I'm happy because everyday more people are searching for a cure for ALS. Thanks Nature for your video, was very illustrative.
Where is the cure after 4 years nothing they don’t care
@@georgecassir if you, sir, think that it's easy doing research, i invite you to study biotechnology engineering, biochemistry, etc. It's so hard working in a lab, money is not enough, time is not enough.
@@Chevalier2211 so if it’s hard to find a cure I ask you to go find a new Job for you sir it is Money and Time to find a cure look for COVID they found but for ALS that don’t care cause no money coming for their pocket
@@georgecassir LOL. You don't have any idea about what are you complaining.
@@Chevalier2211 i have ALS this why I’m complaining please don’t teach me what to say ,since 1940 nothing is done only 2 medicine and for nothing so what do you think ??? LOL
My Grandmother got ALS. She had 4 children. 3 of the 4 have ALS, including my Dad who was just diagnosed on Monday.
I advise you to use Herbal Medicine, that’s what my cousin used to get rid of her ALS Completely. Just visit Dr. Vikraftsambos Herbs
One of my committee professor died of this disease yesterday. May the soul Rest In Peace.
is there any videos illustrating medical basics in such adorable manner ?
ruclips.net/video/7Hk9jct2ozY/видео.html
This is one of the best biology videos ever
My dad had it from 2002 till 2004... past away from it.
This is amazing thank you
The Animation Is Extremely Easy To Praise
Amazing, thanks!
I am making the project on This topic ... And this video really helping me a lot ☺️ .
Nice 3D explanation 👍🏻❣️
Proteins that build up are what's causing the traffic jam into the nuclear port. Maybe start by finding which protein and use an antibody to remove them, also maybe find a way to sneak past the nuclear port thus minimizing congestion. Wish I was a scientist, instead I'm a hairstylist.
my dad has been taking statins from 2017 and got diagnosed with ALS in 2020, and passed away this year
This animation is crazy
How did you acquire the animations ? I would like to use such on a my film about Paroxysmal nocturnal hemoglobiurie. educative video thanks
Great video 👌👌👌👌👌
this video is amazing and so helpful
Has anyone been misdiagnosed with ALS? I’m 42 w a 14 and 3 year old daughters and I don’t want them to watch this happen to me
Nature videos are pure joy
I can't tell if that's sarcastic or just inappropriate - ALS is hardly a joyful topic.
He said the videos were joyful, not the condition!
Who agrees that the voice is like TED Ed voice
Really helpful thank you.
I need this posture
what is the role of sod1 mutant ?
I had no idea how little we knew about this.
So scary
There is no mention of super oxide demutase .
A rare gene produces the Valosin Protein Disease which can be responsible for Paget's disease ( the bone disease) ALS (MND) Parkinson's and certain types of dementia which is why a variety of these diseases can be found in families where the rare gene is inherited. It might be possible to slow down this degeneration of cells by certain supplements which boost glutathione which is necessary for regeneration of cells involved in tissue building and repair, hopefully scientists will do more research in this area.
why does this happen exclusively to motor neurons?
Good question! Not yet known. Could have to do with the fact that motor neurons have very long axons. Or because these cells are more sensitive to some neurotransmitters .
Ludo Van Den Bosch that would make it more common in motor rather than exclusive
I have noticed alot of people including hawkings with als played sports, could it be as simple as some type of chemical exposure + a personal deficiency that makes some vulnerable?
If it was it would have probably been cured by now
@@Peacock__ you think so? Or atleast a form of treatment? Meaning like a bacterial infection in the brain near the motor cortex or long term damage to the nerves from things like injury, trauma or poor nutrition form free radicals
@@mexicanchamp2282 its got nothing to do with bacteria. Its the systematic degradation of motor neurones. There's actually a genetic condition which causes people to develeop it early which means it's 100 percent not bacterial - it could be all genetic, we don't know, there's not enough research or evidence.
Does anyone still doubt natural herbs? I have seen the great importance of natural herbs and the wonderful work they have done in people's lives. I wonder why people still spend their money on surgeries, injections, and medications every time they get sick. Natural herbs can cure all kinds of diseases, including, prostatitis, herpes, als diabetics, asthma, cancer, hepatitis, etc. I have seen it with my own eyes. I was cured of irritable bowel syndrome and my sister and her husband were cured of herpes by Hopkins who uses natural herbs to cure different types of illnesses. Even Hopkins proved to the whole world that natural herbs can cure all diseases and he healed countless people using natural herbs. I know it's hard to believe, but I am a living testimony. There is nothing wrong with trying herbs. Contact Dr. (email). dr.hopkinsherbalcure00@gmail.com Come and thank me later ✌️✌️
..
@@Peacock__ my father was diagnosed with ALS September 2019 , since the prognosis he has lost the ability to speak , struggles to chew and swallow , his arm strength is minimal on his best days and he’s losing control of his balance and neck muscles .he has began to decline not only in health but mentally as well as he has given up the fight it seems , i couldn’t just watch my dad dying so i decided to go into the internet for a possible solution and luckily i saw a Facebook post singing the praises of a herbal medicine from Dr SANTY that someone with ALS used and got cured and quickly contacted the email and order for the herbal medicine and since i started using the medicine my dad have recovered greatly . I am so happy and thanks to Dr SANTY for reviving my dad. you can contact him for the ALS herbal medicine via his email dr.santyjatto @ gmail.com whtasapp +2348145243120
crazy stuff, informative video
my father was diagnosed with ALS September 2019 , since the prognosis he has lost the ability to speak , struggles to chew and swallow , his arm strength is minimal on his best days and he’s losing control of his balance and neck muscles .he has began to decline not only in health but mentally as well as he has given up the fight it seems , i couldn’t just watch my dad dying so i decided to go into the internet for a possible solution and luckily i saw a Facebook post singing the praises of a herbal medicine from Dr SANTY that someone with ALS used and got cured and quickly contacted the email and order for the herbal medicine and since i started using the medicine my dad have recovered greatly . I am so happy and thanks to Dr SANTY for reviving my dad. you can contact him for the ALS herbal medicine via his email dr.santyjatto @ gmail.com whtasapp +2348145243120
RIP Steven Hillenburg
Can ALS cause by nerve injury?
Stephen Hillenburg was Diagnosed with this. D:
I'm glad I'm not the only one here for Stephen. Rip Stephen.
@TOM Two Stephen Hs died from ALS, Hawking and Hillenburg.
Does anyone still doubt natural herbs? I have seen the great importance of natural herbs and the wonderful work they have done in people's lives. I wonder why people still spend their money on surgeries, injections, and medications every time they get sick. Natural herbs can cure all kinds of diseases, including, prostatitis, herpes, als diabetics, asthma, cancer, hepatitis, etc. I have seen it with my own eyes. I was cured of irritable bowel syndrome and my sister and her husband were cured of herpes by Hopkins who uses natural herbs to cure different types of illnesses. Even Hopkins proved to the whole world that natural herbs can cure all diseases and he healed countless people using natural herbs. I know it's hard to believe, but I am a living testimony. There is nothing wrong with trying herbs. Contact Dr. (email). dr.hopkinsherbalcure00@gmail.com Come and thank me later ✌️✌️
..
And now he’s gone as of 2018.
just 💖
are these protein aggregates the same as the protein aggregates responsible for Parkinson disease? (α-synuclein and some other proteins.)
stephen hillenburg died from this disease rip
depth of content worthy of nature journal. however agreeing with another commenter that key questions are skipped, why does it only affect motor neurons etc, which could have been touched on by one sentence, e.g. it's not clear whether. That could have improved the quality of the video tremendously
Plz help me I have ALS mnd my age is 36 years
I‘m not even 30 yet and I have this.
So sorry
Fuck.
How are you? Hope you have a Slow Progression. Much Love !!
Luana Vasco my dad is suffering from ALS
Does anyone still doubt natural herbs? I have seen the great importance of natural herbs and the wonderful work they have done in people's lives. I wonder why people still spend their money on surgeries, injections, and medications every time they get sick. Natural herbs can cure all kinds of diseases, including, prostatitis, herpes, als diabetics, asthma, cancer, hepatitis, etc. I have seen it with my own eyes. I was cured of irritable bowel syndrome and my sister and her husband were cured of herpes by Hopkins who uses natural herbs to cure different types of illnesses. Even Hopkins proved to the whole world that natural herbs can cure all diseases and he healed countless people using natural herbs. I know it's hard to believe, but I am a living testimony. There is nothing wrong with trying herbs. Contact Dr. (email). dr.hopkinsherbalcure00@gmail.com Come and thank me later ✌️✌️
..
Calma
My mom died because of ALS :
ALS ka koi ilaaj hai please batao
Age 40 /m
🙏🙏
Didn’t Stephen Hillenburg die from this?
PLEASE END ALS !!!
Where you from
My mom got officially diagnosed today
There's herbal medicine for ALS in UK and it cure completely within 21 days and no side effect.
I'm a living testimony.
You can get it from Vikraft pharmacy.contact
WhatsApp:+14062211732
Dr.rabiuvikraft@gmail.com
I did some research and ALS is caused by mitochondrial dysfunction that is caused by exposure to certain pesticides in gardening and agriculture, formaldehyde in diesel/jet fumes, formaldehyde in corpse preservation, pathegons in algal blooms in dirty water. As a result the following professions are higher risk for developping ALS: Professional outdoor sport players, professional gardners, professional pilots and truck drivers professional water skiers, militairy personal; and funeral directors
سر میں پاکستان سے ھوں mnd ALS کامریض ھوں 2سال ھو گئےہیں چل نہین سکھتا ھوں بول بھی نہیں سکھتا ھوں اللہ تعالی کے واسطے جواب دے
Aryan kahan sa ho men b pk sa hn and 5month pehly diagnose hwa ha elaj krwaya kahin sa k nae
@@aadilabbasi6195 aap kaha ho
Stephen Hawking have this Disease and i wanna learn What Does ALS do
For now it still kills, but its day is coming and its not that far away
@@someoneyoudontknowtrades no they will never find a cure for it
This is how stephen hillenburg died
very scary ii Have a Question ii Have to ReSearch more it's Been about 4🌎 Days Now My Left ✋ Hand Feel very Numb Numb and can't pick up a cup of water Not to Good But I Have Noo pain i Think i Got to make a Doctor appointment
ii Remember My Favorite TvShow of StarGate Universe and The Nurse Got that aLs disease inn the TvShow and she was washing clothes and Rub Her ✋ Hand it Look Like? she was pain ???
iiiiiiiii am scared of Doctors i didn't seen one when i was the age of 18 and Going to Be 30 in 8-18-88
A. Heere
I think i have als? I keep having trouble taking big breath, my muscle kee0 having cramps, my eyes randomly twitching, my leg kept getting randomly cramp my finger randomly keep twitching and moving im scared do i have als? I not sure my muscle also begin to feel a bit weak
Thanks so much Dr Alaho Olu on RUclips first of all for who you are as a person thank you for the wonderful work that you do for people in general no matter where you are I will always listen to your podcast and refer people to you because you care about people and the human body I listen to other people but you talk about the true disturbances disorders that means things that are out of order in the human system thanks 🙏 for curing my Amyotrophic lateral Sclerosis disease (ALS)..
Dr OSABA on RUclips help me get rid of my ALS disease
If I measure your kindness Dr ogie ,it’ll be a 100% because you firstly made me believe in myself, my family,and your medicine I then had the courage to use it, you permanently cured my loving husband from ALS ❤️
every ways you chose leads to death! 😨
Living is a losing game.
@@y__h agree
very well explained. Ayurveda have very good treatment for ALS you can try brihatvat chintamani ras, capsule shilajit, capsule brahmi & capsule ashwagandha from PLANET AYURVEDA
They found a drug for it
Which drug
The diaease of addiction. Addiction from stimulants. Stop before its too late. I seen friends change due to this disease . Be strong. Man made . it didn't make man .
what stimulants
If I measure your kindness Dr ogie ,it’ll be a 100% because you firstly made me believe in myself, my family,and your medicine I then had the courage to use it, you permanently cured my loving husband from ALS ❤️