Inflammation and the Metabolic Response to Injury
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- Опубликовано: 31 июл 2024
- What is the metabolic response to injury and trauma? How does the body respond to pain?
What cascades are initiated by hypovolemia and hemorrhagic shock?
What about all of those circulating hormones and cytokines following injury?
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Sabiston's Textbook of Surgery citizensurgeon.co/Sabiston
Moore's Clinically Oriented Anatomy citizensurgeon.co/Moore
Netter's Anatomical Atlas citizensurgeon.co/Netter
Schwartz Principles of Surgery citizensurgeon.co/Schwartz
Fischer's Mastery of Surgery citizensurgeon.co/Mastery
Zollinger's Atlas of Surgical Operations citizensurgeon.co/Zollinger
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Welcome back friends! In this tutorial we'll take a deep dive into the Metabolic Response to Injury and Trauma. It's a difficult topic and this is a pretty long video so I've provided some shortcuts below!
WHAT YOU ARE GOING TO LEARN
1.). The THREE major factors involved in the body's metabolic response to injury
2.). The hormones critical in the injury response
3.). The most important cytokines involved in injury and their function
FAST FORWARD WITH THESE TIMESTAMPS
Start 00:00
Goals for Understanding 01:14
Why are we learning about the Metabolic Response to Injury 02:00
What are the 3 Major Stimulants of the Body's Response to Injury 02:40
Pain, Fear and Anxiety and Related Hormones 03:11
Hypovolemia, Baroreceptors and Feedback Loops 05:20
Circulating Hormones, Cytokines and Interleukins 08:05
An Awesome Table for Hormones 08:37
Autonomic Nervous System and the Body's Response to Injury 13:32
RAA Axis, Glucagon and Insulin 15:49
Another Awesome Table for Cytokines 18:21
Summary and Tying it All Together 21:02
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WHO AM I?
I'm Dr. Erik Pearson, FACS and I am a board certified pediatric surgeon living in Las Vegas. I make surgical education videos on all topics in general surgery as well as talks on lifestyle design as a surgeon, book reviews, and studying effectively. I also write a weekly newsletter called the Saturday Six where I identify Six different discoveries of the week. You can get the weekly newsletter by signing up to the CITIZENSURGEON Community!
REFERENCES
Norton's General Surgery Textbook - citizensurgeon.co/Norton
DISCLAIMER
While my aim is to help educate you for the ward, the surgical ICU, the operating room and your exams remember these videos are not a replacement for your reading, your medical school and residency preparation and most important your own decision making. Good luck and enjoy!
Affiliate Links - There are a few links in the description that may lead to a kickback to me to help support the channel.
I’m writing a paper for A&P 2 and i just wanted to thank you for answering questions I wasn’t able to find!
Thank you so much doctor
I have watched this and then read the chapter from Bailey and Love .. awesome
I really like your simplification of complex concepts
JEFFLAKRONIA1 thanks so much for the feedback, it’s definitely an overwhelming topic and I’m glad the talk made it a little more clear!
Your clear explanations rescued me from confusion. Thank you!
I love that so much!!
Dr, I'm more then thankful and surprised that you put every important piece of information regarding the topic in just under 25 minutes, you truly are a genius!
Thanks for such an awesome and supportive comment, that was my first video now over two years ago and it continues to be a good one! Such an important topic! Let me know what else you would like to learn…
I am a surgical resident preparing for my exams, finding your channel is a blessing.
please keep it up.
the0master200 great to hear, good luck with your exams! More topics on the way if there is anything you want to hear about definitely let me know
@@citizensurgeon Thank you so much Dr. You are so kind.
Well, I'd suggest continuing with the basics, such as, surgical infection, pre-operative planning and post-operative care, and surgical critical care and bedside procedures.
the0master200 certainly, the next video is planned for bleeding, transition and Hemostasis, surgical infection and wounds to follow. Great idea for bedside procedures, thank you!
@@citizensurgeon you are welcome Dr.
I appreciate your rapid responses and willingness to teach.
Looking forward to your future videos.
Hi, so what do you wanna specialize in? I wanna become a surgeon too and rn I’m a third year medical student 🙃
Thanks for this wonderful lecture sir.
Thank you sir for this wonderful video. I'm a second year post graduate student of general surgery in India. I never understood this topic so well. Thank you for making this simplified. Looking forward for more such surgical educational videos.
Alish Mehta I’m so happy you enjoyed it! More on the way!
Thanks sir, please continue.
Billions of thanks for this magnificent summary for metabolic response
Wow, thanks so much, this type of feedback gives me the fuel to make more content. I certainly appreciate it. What topic do you want to hear about next?
U totally nailed it.
Love for this ...
Love that! Sorry for the delayed reply somehow I missed this! Thank you. If there is anything you want to learn please let me know!
It's a breathtaking damn perfect summary! Thank you so much!
Thanks so much! First video I ever did :)
Thank you so much for this doc!!! Definitely helped me in studying for my exam
Hope the exams continue to go well!!
Thanks for making this so simple!
Thank you for the feedback! It’s definitely a complicated topic that comes down to just a couple of main players. I’m very happy to hear that it was helpful!
thank so much Doctor for this well elucidated lecture.
Awesome thank you for the feedback!!
Thank you 👍🏼
Thank you so much for this beautiful lecture ❤
Thanks so much for the feedback I’m happy you enjoyed it!
Really amazing helpful ,keep posty❤
Awesome so excited you loved it!
I'm not even a medical student and I learned a ton from this. Thank you!
Awesome, pumped that you enjoyed it!
This should be patented, laminated & sold.... Never seen a summary that cleared so much confusion. Thank you sir!...Absolutely succint!...
Love that! Thank you! I think it’s time for an update!
Thank you so much for this, Dr!
Absolutely! Hope it helped!
Perfect 🙏💯
This lecture really helped filling in the gaps, Thank you! 🙏🏻
Absolutely! Thanks for watching, tell your friends!
Thank you Dr Erick pearson
You helped me understand
Abdiaziz Waasuge thank you for the feedback! Part three coming up this week. If there is anything I can do to make them better let me know!
Subscribed, fantastic lecture and great channel!
Thank you, Doctor.
Thank you for the feedback! And welcome, let me know if there is a topic you want to learn about!
@@citizensurgeon Thank you for the kind words, I'm honored.
So far, everything I needed to for the first semester is already covered here which is great!
For the second semester which will be starting in the next month, I would absolutely love to prepare myself with your fantastic lectures, so if you can do any of the following topics, that'd be great!
-Oncology (principles)
-Surgical Anastomosis
-Vascular Surgery
-Burns
Thank you!
@@muqtadaqutaiba2882 you got it, should be able to hit a couple of those!
thank you very much sir for this wonderful video
rose lin I’m glad you enjoyed it, more to come!
Thanks for all this info!!! 🙌🏼🙌🏼
Fabiana Zaninotti you are welcome!
Thank you for this wonderful lecture
Thank you so much for the feedback!
Thank u
You are welcome I’m so glad you enjoyed it! Sorry for the late reply!
So glad i found your channel 🤗🤗
Paromita Sarker totally awesome thanks for the feedback!
I’m a 2nd year medical student, I just now found out about your channel doc! Thanks! And stay safe
Awesome thanks so much for the feedback, if there is a topic you want to learn about let me know. I have a few talks ready to post!
I think you're a Filipino, just like me. High five dude!
@@citizensurgeon Please talk about neurologic cases (common cases such as traumatic head injuries), Thyroid disorders, Gall bladder disorders, and any common emergency cases as well. It would be a great help if you'll discuss it Sir since these are common in our setting. Thank you!
Thank you
Absolutely! Glad you enjoyed it! If there is another topic you would like let me know. Be safe. Be well!
It is so good , Thank you
So glad you enjoyed it!
Thanks Doc
You are welcome!
Amazing doc gud job
Mona Kanwal Thanks for the feedback Mona, recording Surgical Nutrition today and should have it out by tomorrow!
Thank you so much for this video. Now I can read the topic without having a headache 😂😂
Thank you so much! This is the type of feedback that keeps me pumped up and excited to make more videos! Let me know if you have any topics you would like covered!
Thank you for being more than my college lecturer
That’s awesome thanks for the feedback!
Thank you sir 🙏 ☺
You are welcome, fever series coming this week!
@@citizensurgeon thank you sir... I'm from India 🇮🇳. Can you cross the whole chapters of surgery one by one.. if its lengthy videos .. its ok for us .
Actually I saw ur last video on 2 months ago.. that time I'm so little bit up set. Now I'm happy sir ☺ 😊
Thanks for this great channel
Is evernote pediatric surgery note is public ?
Thank you! It’s not public but I would definitely encourage you to find a few mates and create your own. A huge part of the value is creating what you think is important! Good luck with your studies!!
U are the best
Awesome! Thanks!
Thank you so much for this channel, doctor! This is a huge help in my preparation for my board exams :)
P.S.
I'd just like to respectfully point out the ff (based on berne & levy's physiology textbook):
aortic and carotid BODY = peripheral CHEMOreceptors
aortic and carotid SINUS = BAROreceptors
dr u mentioned that glycolysis is anabolic process and it is inhibited during injury which it is wrong
Thanks for the feedback, do you have the time stamp I mentioned that? My apologies if I made a mistake, glycolysis is certainly catabolic!
Omg thank youuu
Awesome! So glad you enjoyed it. The next video on bleeding disorders will be out tomorrow!
Doing a rotation in surgery in Ghana had to give a presentation on this topic today ... your video saved me😊. Am hooked
This is wonderful, thank you! :).... Allow me to correct an info: Arterial baroreceptors are located within the carotid sinuses not the carotid body
Thank you for the correction Malek!
Please increase the volume in further videos.
Thanks for the technical feedback! Much needed! I can say that the early videos on 20/21 were low on the volume side and too much background music/noise, I think now I have it dialed in :)
6:00
I have one comment to make as feedback, please try to make the videos have higher volume, my phone and laptop both can't seem to be loud enough for me to hear you clearly.
the0master200 that is fantastic, thank you for letting me know, learning how to edit :)
@@citizensurgeon appreciate it Dr.
sadly i can't get acces to the Evernote page, it says 'error' please help
Oh dang, I’ll fix that!
@@citizensurgeon thanx, let me know please when you update it that page would save my life, appreciate it.
👌👌👌👏👏👏🙏🙏🙏
Thanks so much! An oldie but a goodie, gotta make an update!
The music distracts my attention so annoying 😭🥲
Thank you
Absolutely! Glad you enjoyed it!