PyMOL ligand-protein interactions | PyMOL tutorial | Protein Data Bank | Basic Science Series

Поделиться
HTML-код
  • Опубликовано: 3 дек 2024

Комментарии • 72

  • @Shadow-bx8ri
    @Shadow-bx8ri 2 года назад +4

    Your content and way of explaining is out of the world sir. Thanks a lot for clearing out long term doubt.

  • @DocScoop7
    @DocScoop7 8 месяцев назад +1

    it was so helpful that i immediately subscribed the channel!! sending love from Shanghai

  • @Amir-jn5mo
    @Amir-jn5mo Год назад +3

    Amazing video. I had no clue what to even do in pyMOL as it looked intimidating. Now I can easily clean up a protein and focus on presenting the binding pocket im interested in

  • @egowong317
    @egowong317 11 месяцев назад +2

    This is very helpful - thank you very much Professor!

  • @gl0wsticks659
    @gl0wsticks659 8 дней назад

    amazing video, thank you so much!

  • @adampruska1738
    @adampruska1738 Год назад +1

    Thank you very much. It was really helpful and speeded up my work efficiency with PyMol

  • @nonlawat
    @nonlawat Месяц назад +1

    thanks so much!!!
    so easy to follow

  • @bangnikabang6501
    @bangnikabang6501 Год назад

    oh my God. sir, I love you. everywhere else the instruction is so sparse and general. thank you !!!

  • @robertmuller1881
    @robertmuller1881 Год назад +1

    Very clear - thank you

  • @marufislam3777
    @marufislam3777 Год назад +2

    Thank you so much, sir. Can we get more tutorials as you said in this video? Like: "Finding the residues in the ligand binding pocket."

  • @manishmishra9177
    @manishmishra9177 2 года назад +7

    show sticks, byres all within 5 of ligand
    For those who coudn't see the screen like me. copy paste this cmd

    • @BasicScienceSeries
      @BasicScienceSeries  2 года назад +2

      Use laptop if you want to watch the video it won't be helpful with mobile phones. Thanks for your comment 🙏🏼

    • @manishmishra9177
      @manishmishra9177 2 года назад

      @@BasicScienceSeries Can you make a video on how to calculate the volume of substrate binding site? Thanks in advance... :)

    • @ikaoktavianawati4736
      @ikaoktavianawati4736 10 месяцев назад

      Thanks, it helps alot. English is not my first language, so it sounds unclear to me.

  • @matthewadihonneyamos8723
    @matthewadihonneyamos8723 2 года назад +1

    thank you, sir!!

  • @imenfathallah5788
    @imenfathallah5788 2 года назад +1

    thank you for this video

  • @vigneshpandi5722
    @vigneshpandi5722 4 месяца назад +1

    Thanks 😊

  • @vamsivardhan5403
    @vamsivardhan5403 6 месяцев назад +1

    The tutorial was absolutely fantastic and made to involve more but I could not find the link for the continuation of this video regarding labelling for each residue,, can anyone share the continuation of this video link plzz

    • @BasicScienceSeries
      @BasicScienceSeries  6 месяцев назад +1

      Will try to make more useful more, stay tuned for more 🙏🏻🙏🏻Thank you

  • @manognak7406
    @manognak7406 2 месяца назад +1

    HELLO Sir, thanks for this amazing tutorial. How will we know what chains to delete in the protein molecule? ( If the chains are non identical). Is there any criteria for that? Also, can a ligand be in its 2D form for docking?

    • @BasicScienceSeries
      @BasicScienceSeries  2 месяца назад +1

      Well by manually selecting the chains and then go to remove object

  • @Yellownealy
    @Yellownealy Год назад +1

    Can you do protein-protein binding affinity? Like binding sites of an antibody to a particular cell-surface protein?

  • @sarinasarina3973
    @sarinasarina3973 2 года назад +1

    thank you sir. everything is going well except when tap the bottom"S" at the underside bar no sequence information occured.

    • @BasicScienceSeries
      @BasicScienceSeries  2 года назад +1

      So nice of you : ) Thank you so much for your kind support and for your comment as well.. It should work if you are not able to get the sequence, try reinstalling the software again.

  • @dhruvipatel4144
    @dhruvipatel4144 Год назад +1

    Hello sir, how do we get XYZ coordinates of a particular ligand and it's interaction with other molecules on the PDB?

  • @luluingram3735
    @luluingram3735 2 года назад +1

    life saver

  • @uos.chemist1437
    @uos.chemist1437 Месяц назад +1

    Dear I have performed docking using pyrx and visualized using discovery studio. but I want to visualized through pymol+lingplot. What I do.
    Share any video or details
    Thanks

    • @BasicScienceSeries
      @BasicScienceSeries  Месяц назад +1

      That's a great question, let me search on it and hopefully I ll bring a video on it soon 🙏🏻🙏🏻

  • @karenluiselang3423
    @karenluiselang3423 3 года назад +3

    Dear, what's the comand for select the residues close to the ligant? Thank you very much.

    • @BasicScienceSeries
      @BasicScienceSeries  3 года назад +2

      Check this on out, number of commands with examples: pymolwiki.org/index.php/Selection_Algebra

    • @ikaoktavianawati4736
      @ikaoktavianawati4736 10 месяцев назад

      yes, since the picture is not clear enough to see 😢

  • @israthumayunslifeinchina4996
    @israthumayunslifeinchina4996 6 месяцев назад +1

    show sticks, by res all within 5 ligand
    i was write according to your information but residues not coming, in your video it is also not clear, can you please give me detail

    • @BasicScienceSeries
      @BasicScienceSeries  5 месяцев назад +1

      Can you provide more details on the issue what command you are following ??

  • @fatimagenetics
    @fatimagenetics Год назад +1

    i need to watch next part,,,
    kindly provide me i haven't found

  • @amalelfoly5944
    @amalelfoly5944 Год назад +1

    could you please write the command of show sticks you used

  • @Fordance100
    @Fordance100 5 месяцев назад +1

    Good video. Fonts are too small.

  • @alchemista947
    @alchemista947 2 года назад +1

    when i select chain the ligand also selected i dont know why

    • @BasicScienceSeries
      @BasicScienceSeries  2 года назад +2

      Thank you so much for your kind support and for your comment as well.. You need to select the residue option not the chain option at the bottom of the right corner. Play around I am sure you will figure it out. Which molecular you are exploring...

  • @waqi409
    @waqi409 Год назад +1

    The command is not clearly visible mention in the comments, please

    • @BasicScienceSeries
      @BasicScienceSeries  Год назад

      Please check the comment section, if it is not posted already, let me know thanks 🙏🏼

  • @aneeshaanilkumar3935
    @aneeshaanilkumar3935 8 месяцев назад

    Sir How to design anti drug conjugation

  • @JohnathonDubourg-g6k
    @JohnathonDubourg-g6k 2 месяца назад +1

    Erica Extensions

  • @JenniferHernandez-r9p
    @JenniferHernandez-r9p Месяц назад +1

    Kevon Corners

  • @fatimagenetics
    @fatimagenetics Год назад +1

    provide me link of next video

  • @AmyAnderson-f6g
    @AmyAnderson-f6g 2 месяца назад +1

    Boehm Spring

  • @TrudyMarquez-c3p
    @TrudyMarquez-c3p 2 месяца назад

    Crist Forges

  • @SharlaClonch-k1f
    @SharlaClonch-k1f 2 месяца назад +1

    Moshe Trail