Pre-docking Tutorial: Active sites using CASTp, PyMOL and use of Open Babel

[@HEMALATHACHATLA-y2s]

really more helpful, please do like this simple and smart, thq.

[@parthrahatekar1764]

important content. good work 👍

[@thestudentguide951]

Thank you Parth.

[@BioVoyage_Ventures]

thanks you saved lots of time

[@Shivraj_101]

Very Educational Video 👍

[@thestudentguide951]

Thank you sir.

[@hamzaali-ni8qg]

If there is no ligand in protein then how we find the activesite

[@thestudentguide951]

Thank you for the question.
Yes you can still find the the active sites through different web servers or software available. You may use AutoDock Tools for that, and place the entire protein in the grid box. This automatically detects the favorable active/binding sites. You can even try using CastP.

[@aichakerassa8857]

thank you for your video.
my qestion , what is the difference between the active site & binding site ?

[@thestudentguide951]

Thank you for the question.
Active site contains the binding site that binds specifically to the substrate. In other words, binding site is a part of the active site. You can say that the active site helps in the binding of the ligand.

[@Shivraj_101]

Good content 🙏

[@Shivraj_101]

Thank u sir

[@umii27]

I have a question , i downloaded the structure using Uniprot and i m not getting pdb I'd for the same protein , how can I find pdb I'd ?
thank you

[@sumitjadhav1077]

👍👌👌

[@johavlog4915]

Hi
I’m olso live in Finland and can you help me