Arrhythmogenic right ventricular cardiomyopathy (ARVC) - pathophysiology, investigations, treatment

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"Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable, under-recognised heart muscle disorder that predominately affect the right ventricle increasing the risk of arrhythmias.
Progressive loss of right ventricular myocardium and its replacement by fibrofatty tissue is the pathological hallmark of the disease.
Mutations in genes encoding desmosomal proteins (which are important in cell to cell adhesion) play a key role the pathogenesis. Issues with cell to cell adhesion as the pathological basis of ARVC was first described in patient with Naxos disease who had ARVC, palmoplantar keratosis and wooly hair."
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[@Casualgamer.2196]

Big help very informative. It cleared a question during working hours.

[@arbabkhan1700]

That was VERY informative. Thank you!

[@EGD00]

You could have explained more... For eg, what epsilon wave means, or why the t wave is inverted.

[@al-hassanhaider9327]

Thank you so much

[@ebgmth]

Nice subject 💙 I am studying cardiology now😍

[@yigido1862]

is disease damage all gap junctions or some gap junctions?
in desmoglein 1 damage to cause bullous disease. i will remember this disease with fats. fats cardiac disease caused desmoglein 2 damaged.

[@TheVipereagle]

What minerals and amino acid antioxidants are needed to Fix and manage this?

[@nateshsudarshan3743]

Awesome video

[@komprestaSiba]

Thank you for information😊

[@DevRaj-vk6fm]

one of my friend is suffering from it ...........

[@hstudy8406]

Awesome

[@amrsaeed1231]

Miss the old drawings. These new (digitized?) ones are not that catchy. Good job overall.

[@Easycheesypeasy]

i am in middle school this was helpful

[@thedudeabides97]

4:32 you mean the 3rd to 5th decade of life? That would be 20-40

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❤

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[@PhysioMantra]

Good content..👍
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