Ebola: The Disease of Nightmares
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- Опубликовано: 4 окт 2024
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Source/Further reading:
CDC, Overview: www.cdc.gov/vh...
UK government, detailed fact sheet on Ebola: www.gov.uk/gov...
NYT, history of Ebola in 24 outbreaks: www.nytimes.co...
FT, interview with virologist who helped uncover first Ebola outbreak (paywall): www.ft.com/con...
Concern USA, story of the 2014 outbreak: www.concernusa...
Concern, Ebola myths: www.concernusa...
Stat News, inside story of the Ebola vaccine: www.statnews.c...
NYTimes, Ebola treatments successful: www.nytimes.co...
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Yipee
Looked like you were about to get sick drinking that stuff lmao
£80 a month way to expensive and not worth it
Simon please do one about yourself
🤜🏻🤛🏿
Fact Boy over here shilling Soylent Green. 🤣
Dr Stella Ameyo Adadevoh deserves to be mentioned. She died treating the first ebola patient in Nigeria. She was able to diagnose him right away and forced him into isolation, which likely saved many lives.
She was dedicated to her job and when other people in authority told her to let him out of hospital she fought hard to keep him there to protect other people. Many people in close contact with Patrick Sawyer died of Ebola and we will probably never know if he wanted to infect other people in Nigeria or if he just denied he had Ebola because it was too terrifying to acknowledge after his sister dying from it. Doctor Stella Adedevoh was a hero in her efforts to prevent more deaths and challenging others who threatened the hospital if they did not set Patrick Sawyer free.
So she's a war criminal for saving those cannibals..
@@sauerkrautvonbraun4590 how??
@@elliekingham882 _she's a war criminal_
hOwW?
_for saving those cannibals_
@@sauerkrautvonbraun4590 What cannibals?
I had a patient die of DIC (caused by cancer)
It was the most horrific thing I have ever seen, blood coming out of her eyes, ears, and even her nail beds.
She was gone in minutes, and this was in a world leading hospital.
Poor woman💔😰
Can you explain what DIC is? It comes up on TV shows, but doesn't really explain what it is, or what causes it
@@madjennie3417 I can't say I blame them, it's...it's really convoluted. Basically, a person's clotting factors become over-active, and start clotting in places they shouldn't. The result is blocked blood vessels, and it uses up all the clotting factors in the blood, so anywhere that starts bleeding won't stop.
The proteins that trigger this are excreted by a lot of immune cells, as well as some tumours, hence why cancers and infections can cause it.
This is the very barebones explanation, hope I've managed to explain it well enough🥴
@@madjennie3417 he mentioned it in the video; Disseminated intravascular coagulation. When ur body’s blood clotting function doesn’t work properly, leading to blood having no choice but to leak out of different holes in ur body. Happens from serious illness, injury or infection; anything that stops blood being able to clog basically.
@@madjennie3417 Blood Scientist here. It's when the body starts making small clots in your blood stream randomly, rather than in response to a cut or tearning a blood vessel. This means all of the clotting factors, platelets etc that are required to make clots are used up, so then there is nothing left to deal with the normal small breaks & tears made in vessels by normal wear & tear. Basically, you make loads of inappropriate small clots so then there's nothing left to make appropriate clots. Our DIC patient's receive massive transfusions of Red Blood Cells, Platelets & Clotting Factors to try & stop them bleeding to death. It's clinically extremely urgent & we lost a pregnant woman last year after getting DIC caused by an amniotic fluid embolism, which was so so tragic. If we see any evidence of DIC in lab results we have to tell a consultant immediately.
Out of all the pandemics, ebola is one that worries me. Not because it was relevant in my area, just the brutality of the illness is an awful way to go
Absolutely 👏
Yeah. I was around 8 or nine when I found out Ebola existed because of the epidemic* in 2014. I was ill with the flu at the time and I wasn't able to move. I was sick. My stomach was messed up and I kept vomiting. I remember thinking I was dying of Ebola. If a simple flu made me suffer that bad, then I cannot imagine the terror and pain people go through while dying of it.
the fact that it’s not relevant in your area should make you not worried
Try rabies my man
@@awe331 I worry for others who suffer indiscriminately and unfairly. It's heart breaking hearing stories of these lives lost, but at least scientists and doctors can eventually learn enough to prevent or combat illnesses
Nothing in this video is over dramatically depicted. Haemorrhagic fever that spreads is a nightmare and I’m a medical doctor. Back in 2014, the hospital i was working for, was appointed as a potential destination for any cases that may come up, so we had the leading infectious diseases specialist giving us a full briefing and also drills for management, handling and safety procedures. It was like «don’t get it or you re screwed»
Ebola might have been the plan-demic, but the powers-that-be decided it was far too dangerous. They went with Covid, because it was not as deadly.
It's insidious, because caring for the infected people is what puts you at the greatest risk. If you don't have the proper PPE and proper sanitation procedures, you can't care for the ill. You would essentially just have to gather up the sick and keep anyone from being near them or touching them. You'd have to have family members stand outside, watching their loved ones die. You couldn't even have the body prepared for a traditional funeral.
I mean you might not even be able to treat some of them. You'd have to ration your resources on those you think would be most likely to survive. If a doctor got infected you'd have to try and save them.
@@dr.altoclef9255 Like a leper colony.
So many comments on this video are light hearted, but man is this virus terrifying
Was in 14 even Inmazeb on the marked at that time?
Not even a real Vaccine right?
And the newest studies show that it may survive in the Liquor way after the Infection endet.
Means Antibodys are near to useless.
Simon could literally make a 30 minute video about the process of drying paint and I’d watch every minute
factboi fanboi 🤌
That should be his next April fools video.
Even the sponsorship bit was interesting 😂
@@CactusBravo42 Is it me or did it look like he really hated the taste of that green stuff?
I could see him doing that on Brain Blaze....
I was diagnosed with DIC during my first cancer. Doctor tried for a week to get some sort of hold on it before my surgery. He wasn't sure I wouldn't bleed to death on the table but he was sure the cancer would kill me quickly without the surgery. Not a favorable position to be in but you go with me one that offers hope, no matter how slender the thread. Blessed.
glad u survived
congrats on your survival
I guess that explains why I had to take warfarin (a blood thinner) for years during chemo. They mentioned it was to prevent blood clots but i didnt know about DIC at the time. Glad you're still alive.
God is good!Amen 🙏
I hope your still here im sorry you had to go through that
"Not big enough of a problem to be profitable" that statement haunts me, and always has. It's a blatant statement of how messed up EVERY government and business is today. Or rather I guess, always has been.
Capitalism isn't sustainable because of this
Sadly it is the case, it's also why most medical research is funded by the federal government because otherwise pharma companies wouldn't bother with the small populations of some diseases.
Theyre messed up because we are messed up. If the population cared and there was a demand for it then theyd make it happen.
thank capitalism for that one.
Profit corrupts all it touches. Parasitical multinational companies would gladly kill you and all of your coworkers for a 1% increase in profit.
I'm a medical technologist and I'm absolutely terrified of this virus. It's like one of the final boss of all the viruses.
It's an hemorrhagic fever which causes you to bleed internally and externally.
Ebola synthesizes Glycoprotein which is a form of protein which inhibits integrins (receptors that signals platelet and coagulation factors) and causes liver damage, hence leading to improper blood clotting. At the end-game of Ebola infection, well normally, cytokines helps the body to protect itself from infection but Ebola tricks our own body to push the "suicide button" (which makes Ebola a tad bit tricker than HIV) This is called cytokine storm. Immune system starts to launch its entire arsenal all at once but causes more damage to the body rather than fixing it. It causes catastrophic damage specially the blood vessels. Take note, with the combination of abnormal clotting factors and destroyed blood vessels, basically your blood starts to leak like - *e v e r y w h e r e*
That’s why they say it pretty much liquifies the body!! Too crazy!
Look at a drug called Ampligen, in animal testing it worked against Ebola
Sounds similar to a recently released poke, especially the cytokine storm.
This virus sounds like a bio-warfare scientists' wet dream.
Bring it
16:14 A huge problem is that some countries in Africa actually do have real organ harvesting factories that the local police don't do anything about, highly likely because many of them are in on it. A lot of citizens live in a legitimate fear of being kidnapped and taken to remote old buildings where they're chained up and never seen again. There was a story on this in 2014 where a mob of motorcycle tour guides in Nigeria were tracking down their kidnapped friend and found one of these places, it's horrifying. While I don't believe the 2014 Ebola outbreaks had anything to do with organ harvesting, I'd say it's totally understandable why some of the locals would be fearful of this being a possibility.
I watched a MrBallen video about this topic those motorcycle people were called “Okadas” MrBallen is a storyteller that will shiver your Timbers
Halfway through the video but there are cultural issues that lead to the outbreak as well. Since rural areas of the Congo still heavily belive in vampires. Any aid workers can be at risk of being mob style attacked.
@@jordonj07 every time I see people talking about Ballen he gets praised as if tho he's some kinda of crypto expert using bots
If countries didn’t shovel money to Africa, the citizens there would’ve been proactive in finding solutions to their problems, because they would have to take their lives back from their brutal warlords.
@@manoftruth0935 yeah? And what brought you to that conclusion? History shows the opposite to be the case
I actually didn't know that Ebola had an effective cure yet. As terrifying as a lot of the information in this video was, just hearing that fact alone actually made me very happy.
viruses can’t really be cured. we have anti viral drugs that do work, but usually only shorten the duration and severity of the illness (honestly it’s a little questionable how well they work, they’re ideally taken before you get sick-like if you have cancer and no immune system and thus, are on anti virals). i’m pretty sure the best treatment we have for ebola is still rehydration. it was actually a big debate as to weather IV or oral rehydration was better and i don’t think there’s a medical consensus even now. i’m a pharmacy tech-viruses can’t be cured they’re treated based on your symptoms and your immune system has to fight them. like if you have vomiting and diarrhoea, taking nausea medication, anti diarrhoeals, fever reducer if you have one, NSAIDs for body aches, etc. are the best treatments.
Sad, however, that it required a large outbreak for pharma companies to get the incentive to manufacture a vaccine.
Wait until the antivaxxers decide this one has a microchip in too . . .
yeah as soon as it comes to america there's a cure lmao
@@henryparsons3716 cope
When we had the Ebola scare here in America, I volunteered for our hospital’s Ebola response team (I am a RN). We all knew if it really hit, we’d probably be among the first to die. I was talking about it with the docs, and said if it got real, I was going to get them to sign a DNR order on me. One of the traveling docs (anesthesia) said he’d already formulated what he would put in an injection so no one would suffer needlessly, if it came down to it. It was comforting to know we wouldn’t have to live thru feeling our bodies break down, spleens rupture, etc. It was stone cold real to us.
Major respect! My sister is a nurse, and I have mad respect for you Healthcare workers! You guys are heroes 🙏
Sorry what is a DNR
@@tediumluvsit stands for Do Not Resuscitate. The form basically states that if you're having a heart attack or suddenly die or are close to death, you do not want anymore help.
Hooray for the anesthesiologist.
My high school friend (actually my first crush) got Ebola helping people in Liberia. He was airlifted to USA, one of the only of ten Americans who got it. He pulled through 🙏🏼 I was in a mental breakdown state over it, not many people have been touched by it here in North America.
Currently bed bound with a bad case of stomach flu, watching this to remind myself that it could be significantly worse. Great video as always
I can still remember the 2014 Outbreak, and it still gives me chills down my spine some days when I see a specific photo of the virus. I can also remember when one of them died in Texas and it was reported on the news. It terrified the hell out of me at 11 years old.
I remember that. It scared the daylights out of me, too.
It was in Dallas, where I was living at the time. Yeah, that was pretty stressful...
We read The Hot Zone as highschool freshmen in 2012… so when the 2014 outbreak started we were pretty freaked out
Yeah I remember footage of people suspected of being infected and huge groups of people chasing them out of town, it was really sad
We were in Texas and were like, "great, we are all going to die"...I didn't get on a plane after that for years.
Ebola, my nemesis. It was a nightmare to deal with when the outbreak hit in 2014. I not only had patients that were paranoid, but one of our IDMTs ( air force enlisted flying medics) help care for those affected by Ebola in Africa
I may have configured/launched your C-130! I was a crew chief that same year at RAB and we launched missions and supplies to Africa all the time that year and the following. You guys rocked, thank you for your service!
@@hoodrobin781 bruh crew chiefs are cringe
@@MikeMike-dv7iv 🤣
@@MikeMike-dv7iv Aw thanks young lady
I love that the fact that they have an anime profile picture makes me certain they actually are a scientist.
Read The Hot Zone in the early 90s as a middle school kid and I have been both fascinated by and utterly terrified of ebola since. Always enjoy watching videos on it to feel the same way I did when I was young...well done as usual Simon.
The Hot Zone was a great book.
I read it in middle school as well, I’ve written many high school and even college papers on it. I developed a bit of a fascination with it that I still have
Hell yeah that book is amazing; have you read “the demon in the freezer”?
Check out "Crisis in the Red Zone" which is considered a sequel book by the same author, based on the 2014 outbreak! It was terrifying but extremely interesting.
my mom still talks about this book, as a kid I was convinced I was going to get ebola.
I am a nursing student. Think about the remoteness of these villages and lack of resources. Healthcare team members must be completely covered and can only be in the treatment tents for 20 min at a time or overheat. The cocktail of medications a patient needs, is hard to keep up with. Families want tp pay respects to the deceased, but cannot touch or go near their loved one. Bodies must be disposed of properly, careful not to infect soil or water.
Bless you and your colleagues
I remember when I was a little kid and seeing the cover of Newsweek sometime in the 90s - it was on Ebola and alone had something like a 15-20 page spread in the magazine. I was only 9 or 10 years old but I read the whole thing as best as I could. It was terrifying and fascinating all at once. The cover was an ultra magnified image of the virus itself.
I remember that!
At 10 y.old, I was reading National Geographic magazine, the only place I knew would show boobs...😜
I remember reading that too! I became obsessed with microorganisms after
I remember that. I was terrified and fascinated.
Beautiful explanation. A deadly, but isolated disease breaks through because of poverty, fear, and the speed of travel. So horrible that people who were trying to help died so miserably. Thank you so much, Simon.
I remember reading The Hot Zone in highschool and the way the books described how the victims suffered was metal af and terrifying.
It was written so well. It read like fiction which made it even more terrifying because it was actually real
I don’t think “metal” is a good description of someone dying in agony irl my guy
i remember reading The Hot Zone as a young kid. and then Re-Reading it in high school.... I loved it. it was terrorfing, metal AF, and really sparked a lifelong curiousity of exotic diseases. in another life I'd of loved to of been an epidemiologist.
instead I'm a glorified babysitter for boomers who don't know how to use "The Google"
It happened in 1989 at USSAMARID, THE EVENTS OF HOT ZONE!!
"metal af" is honestly a terrible and insensitive way to describe someone's suffering caused by a disease like ebola.
I absolutely love these videos regarding disease. They're the ones that drew me to this channel in the first place.
More sickness, please?
You got your wish! Monkypox incoming for ya!
I was nine in 2014 and I remember hearing about ebola from the news, I saw a segment on it and there was footage of people sick with it. I got so scared of ebola after watching it that I wouldn't use a public restroom because I thought that doing so would put me in contact with infected bodily fluid. I lived near Seattle at the time so I was not in an at risk area, but I was very convinced that if I used a public restroom I would die and also give ebola to my whole family and they would also die. Watching this video I kind of feel justified in my nine year old self's paranoia.
Poor assumptions invariably lead to poor conclusions. So a person with Ebola is not infectious until they are symptomatic. By that point = they will already be largely incapacitated. Thus they will not be walking around using public restrooms etc.. Further you must come into contact with their infected bodily fluids. In other words they are flat out + oozing from their pores and body orifices = and *THAT* is what you must touch to become infected.
@@varyolla435 I'm aware. I was nine I obviously don't believe that anymore, I was just a freaked out kid 😂I said I feel justified because the disease is terrifying and it normal to be freaked out by it.
I was also nine in 2014. The fear for me really kicked in when I heard about the case in Texas. I was convinced the disease would sweep across the country! What a scary few months that was.
Stop you’re making me feel old.
I’ve never had Ebola, but I have had C-Diff. I’m sure the only similarity is that they’re in the gut, but I feel I can still say this with confidence. Not only do you feel like death, sick to no end, and suffering, but the pain. The insufferable pain even opioids couldn’t take away. The pain of your insides literally melting. As cliche as it is to say “words cannot describe pain”, the pain cannot be described by words.
obviously it’s hard to fight epidemics especially in rural areas where healthcare workers can be seen as frightening, but i feel like we set the routine of not caring about diseases with the way we handled ebola. i remember seeing shock footage of it from MSF / doctors without borders & asking my friends at school if they were worried and they went “nah, it’s in africa, why should i care man?”
i feel that culture of not caring cause it’s happening to someone else /some place else/ lead to the current epidemic getting quite bad. i watched a man bleed from every orifice including his pores, wailing in pain as the drug cocktail seemingly did nothing. i watched a man go into respiratory distress from covid in the street, a healthcare worker hit him in the chest a few times with a plastic paddle to try and break up the mucus, it was like wet thumping. you could hear the impact reverberating through 2 layers of clothes & the distance between the lungs & skin. the camera was 10 feet away.
yep. with covid you just have to look at developing countries' vaccination difficulties to be reminded of it. sure, i take my boosters gratefully, but i really would want them to be sent where they're needed more.
Pretty much
I was in Monrovia, Liberia during the Ebola outbreak. On a humanitarian mission with the marine corps and I can say nothing was more horrific then seeing affect individuals with this horror.
Those medical and aid workers that went in to these areas, either by assignment or voluntary, are some of the bravest people around, especially before any treatment was discovered. Needless to say, their selflessness saved countless lives.
They were incredibly brave. For a virus that has killed more than 70% of people afflicted in outbreaks and they still went to help. I was also terrified by this outbreak and I think it would be naive to assume it couldn't spread further. The man, Patrick Sawyer, was travelling and planned on going to a conference. He ripped off some of the equipment that was helping him and splattered blood onto the healthcare workers; who became infected. All it takes is someone with symptoms spreading the disease to healthcare workers and close family and before you know it, it becomes a catastrophic nightmare.
Around 2012, a few years before really anyone in American knew what ebola was, my mom was misdiagnosed with it! A nurse who wasn’t supposed to give any results told my mom the wrong information. We went home and looked it up and we freaked out because we thought she was going to die within a few hours. It was pretty terrifying tbh. Ebola is a horrific disease and hope that it doesn’t pop up again.
Wait a nurse said "hey you have ebola" and just sent her home???
It doesn't sound like she knew what ebola actually was. Maybe she used the wrong word when trying to tell your mom what she had. Because if she had known what it was, they wouldn't have let you leave the hospital.
@@johnnyvivic8730 so then she shouldn’t be a nurse
😂😂😂yeah sure
3:05 - Chapter 1 - His red right hand
6:40 - Chapter 2 - Blood on the tracks
10:10 - Chapter 3 - Raining blood
13:45 - Chapter 4 - Let it bleed
16:45 - Chapter 5 - Tourniquet
- Chapter 6 -
So, DIC isn't so much that your blood vessels leak, it's actually a strange clotting/bleeding combination where your blood clots so much (usually in small vessels) that your body literally uses up all your clotting factors, resulting in spontaneous hemorrhage throughout the body and microclots all throughout capillary beds (resulting in exceptionally poor circulation to the extremities). DIC is absolutely terrifying, and strangely is often treated with both an anticoagulant and by clotting factor replacement (like cryoprecipitate transfusions and often platelet transfusions as well)
Edit: also, in case you're curious, I believe heparin is typically the first-line agent of choice for the anticoagulant, while FFP (fresh frozen plasma (yeah, it's a bit of an oxymoron)) and platelets are typically used initially to replace lost clotting factors/platelets, while cryoprecipitate often (at least at my hospital) has to be ordered from another blood bank (we actually use a local university for our "send-out" blood bank). We can prepare FFP and platelets, but don't have the licensing (or equipment, frankly) neccessary for cryoprecipitate. Cryoprecipitate, by the way, is (basically) a concentrated form of most of the clotting factors in the body (prepared by basically skimming the liquid top of partially frozen plasma). FFP contains the same clotting factors, but requires a vastly larger volume of liquid to be transfused for the same amount of clotting factors to be transfused as a single unit of cryoprecipitate. And please note, all this is the less simple very simplified version, as it gets WAY more complex if you really want to dive deep, so to speak
Exactly this. There's a reason we also call it Death Is Coming.
Glad someone wrote this. Pretty sure I involuntarily pulled a pretty weird face when Simon "described" DIC *lol
@@NPC-fl3gq yeah, I did as well lol. I get it was an attempt to simplify things, but it wasn't as accurate as it could've been while achieving the same goal, at least in my opinion
Holy Adderall
I didn't realize cryoprecipitate was still being used for anything. But then again, my knowledge of it only extends to it being an earlier form of treatment for hemophilia. Thank you for your explanation! 😊
I clearly remember this one day at school, I was in 3rd grade, I saw blood drops on the ground and thought a person in the school had ebola (I lived in south africa, so i kept hearing that the ebola virus would maybe reach us). I was so scared that just the thought of someone having a normal nose bleed, made me feel sick and dizzy, so for the rest of the school day my teacher said I could rest on the class carpet.
Did it actually reach South Africa at the time? Being in high school in America, we were worried about the potential outbreak here as we had a lot of Red Cross nurses and doctors get pushed out to the outbreaks, worried they may bring it home. However, I could only imagine being so close to the epidemic. I probably would’ve fainted too if I saw a mere nosebleed. Absolutely horrifying virus. Bubonic plague is pretty terrifying too, but nowhere near as close to Ebola.
@@barbarradevlin9111 nope :)
Im also south african and remember the ebola posters near our school library, i was worried about it but clearly not as much as you were
The light in the background looks like the Zelda stamina wheel 0:12
Video starts at 1:48 :)
My ex was from Liberia and I remember his mom breaking down when she got the call that two of her brothers died from Ebola in 2014. This disease terrifies me. Especially the Ebola awareness illustrations in Africa. So scary
Airborne ebola is one of the most terrifying things i can think of
That will be catastrophic for the whole world 😕
Rabies has gone airborne.
It wouldn’t spread though because people would know they have it and have to stay home because they are so sick
@@johndole9810 no?
@@johndole9810 uh… no. Rabies is transmitted through saliva. The virus can survive for a few hours at room temperature, and it’s no longer infectious once the contaminated material is dry. Rabies virus need a moist environment to be infectious and spread.
As a microbiologist Ebola is something I have been fascinated with and studying for a long time. I am neither an expert or novice on the subject, but I still found this video very interesting. Good show sir!
I made the video so thank you!
@@gupadre8255 ???????????????????????????????????????????????????????????????????
@@zelkk7049 itbwa mey7
@@gupadre8255 ??????????????????????????????????????????????????????????????
@@zelkk7049 that is ALL
as a person who recently suffered from the flu and is still sort of recovering from it, imagining something so awful that i'd pray to just have the flu again is a terrifying and dark thought
Ebola is a Haemorrhagic Fever like Dengue - in 1990 I was living in Tahiti and caught what is now known as “Severe Dengue” but which in those days was called DHF (Dengue Haemorrhagic Fever) and the symptoms are very similar to Ebola. If I hadn’t been young and comparatively fit it would’ve killed me. Was living in a fairly remote area with a clinic run by a young Medicine grad doing his national service but later discovered I should have been in intensive care.
During the 2014 Ebola outbreak, I was in middle school. The science class I was in just happened to reach its chapter on diseases in December. By then, people in America were already aware of what was going on. I wasn't, because I was a sheltered kid with no internet lol, but you get the idea.
My science teacher sat the class down on the first day of the lesson. He was like 'okay kids, we're gonna do something different today - I'm going to read you a story!' and hey, that sounded like a nice break from taking notes.
The 'story' was actually the first chapter of The Hot Zone, and while most of the class sat there with their mouths open, eyes wide, just staring in sheer terror, something clicked in my mind and I knew I HAD to read the rest of the book. This was pretty much my first exposure to the concept of people dying en masse from invisible enemies and it both terrified and fascinated me. To this day I've never let go of my interest in diseases. It's become a part of me and I wish I could thank that teacher for showing us the book. (Me being autistic and developing an attachment to virology probably also played a part, but no one asked lol)
Honestly, if I wasn't so bent on programming, I would have become a virologist. Sometimes I wish I did. I could talk about this forever - had to delete a huge paragraph just from this comment because I realize nobody wants to read an essay!
Just saying hi as another autistic person interested in disease and viruses!! 👋 if you ever wrote more I would absolutely read it :)
You may be able to put your programming skills in combination with your interest in virology! I know plenty of scientists who could use someone with a techie background and programming skills to make stuff like infection modeling software or even use an AI to predict the specifics regarding infective processes in the cell. I’m not sure if it interests you but I felt it was best to let you know about that potential career option- I myself wanted to do virology but found myself quite interested in oncology!
Also please write that essay, I’d love to read it and compare notes! I did a bit of virology while doing my undergrad and to this day it still fascinates me. Even the humble herpesvirus is wickedly amazing- it lays dormant in our nerves and actually interacts with our immune cells (B cells if I recall correctly) and replicates without lysing or otherwise exploding the cell. In a study with immunocompromised mice, herpesvirus became lethal- it’s also lethal in oysters, an invertebrate that never evolved to have an adaptive immune system. Another weird thing is that it seemed to have evolved with us- simian B herpesvirus in humans is also potentially lethal, but in its natural host the macaque it just causes regular cold sore type lesions. And that’s just herpes! The glycoprotein structures of Ebola, as well as how they interact with our blood vessels to cause that classic hemorrhagic fever, fascinate me as much as they horrify me. And don’t get me started on the weird theories my peers in virology have been throwing around (and sometimes loudly arguing over) regarding long covid!
You still have lots of time to figure out what you want to do.
Been dreading this disease taking off since I was a kid, good to know they're figuring it out.
I dont think my man here is going to rest until he is the king, dare i say owner of RUclips. So much content. Better then a cable package for TV.
Better *than* 🙄
Pandemics and other disasters really have a way of revealing the cracks in the system that were always there, but were easier to ignore when things were normal.
The worst part is trying to convince families not to do burial rituals.
That giant funeral was just stupid. Why would the authorities allow hundreds to touch a body infected with a deadly disease? Then to make matters worse they could just go right back home afterwards.
@@zozzledwolf4653cause africa
After watching videos like this I'm really glad I'm an introvert.
Simon i couldn't agree more with your conclusion! The west is so very disinterested in investing in the economic and governmental changes in Africa that would protect all of us. Allowing this kind of poverty doesn't just hurt " them" it hurts us too. I don't understand why people can't understand that we are all human and we all have to look after one another. As long as we don't epidemics and pandemics will be our new state of being. Thanks for such a great conclusion to the video. I hope that people will take it to heart and start pushing for change from their politicians
It is sad that soo many of the countries in Africa have such a deep cultural saturation of corruption. Billions in aid have already been contributed but end up in the bank accounts of only a few.
@@jdougn2255 this. There are two options for helping African poverty. 1. Committing enough aid as well as missionaries and hoping it trickles down into the population or 2. Conquest and revolution, we forcible overthrow every government in Africa and occupy it for generations until stability is reached.
The Governments of africa need to stabilise themselves, we will aid however we can but we can do nothing about corruption short of regime changes.
Based on the past experiences of the US meddling in other countries governmental affairs, I say we stay as far away from that as possible. Just provide humanitarian aid when needed, otherwise, do not meddle, it never goes well for any involved
They’re too busy plundering the continent like they’ve done for the past few hundred years. The controllers of the world don’t care about us peasants, that’s a cooky conspiracy theory.
@@jennh2096not true
I remember, was 14 in 2014, absolutely terrified me to think that Ebola could get out of control. It terrified me more than Covid did by many increments. Ebola almost certainly spelt a horrific end.
ebola is 10x more terrifying than covid to me because of the way it deteriorates you, at least with severe end stage covid you're usually fully out and unaware but ebola keeps you up the whole time
Rest In Peace to those that passed away.
1:48 start of video
You aren't the hero we deserve but the one we NEED.......thank you!!
Thank you
I was like 9 when ebola swept the news in 2014. When the first case came to the UK, everyone in my class were collectively terrified
People are often afraid of things they are actually ignorant about. It is simply human nature. So despite the deadly nature of Ebola = it is not terribly infectious. If you avoid being exposed to bodily fluids from someone infected with it - who must also be actively ill - you will not catch it. Of course by the time they become symptomatic so as to also become infectious = they quickly thereafter become incapacitated.
So it spread through Africa because of cultural mores which led people to handling the sick/dead instead of letting medical authorities deal with them. Rather than letting people be cared for at hospitals and not handling infected bodies families would do it themselves = and thereby become infected as well.
Pro tip: don’t kill your host too fast else the party stops
I work in the oil fields of the Permian Basin. I believe the story of Red Adair would be a interesting addition to your lineup of Biographics. Love the channel. Thank you sir.
Red was one tough Texan!! Handled the Kuwait oil fires like a BOSS!
I absolutely adore the prehistoric fauna and flora from the Permian of Texas. Greetings from Poland,hope you're satisfied with your job
A friend of mine jumped on a cruise ship with an ebola nurse from Dallas. He spent five days stuck on the ship out of Galveston Texas unable to go ashore in the countries he had paid to see LOL. While the nurse was isolated inside of a room from anybody else, the entire passengers and crew all freaked out and were held when they returned to Port. Another reason never to go on a cruise ship.
Cruise ships are honestly just Petri dishes of juman disease, even with a healthy hearty immune system I'd balk, despite the experience seeming interesting
Humbly requesting George Carlin. A comedian and satirist who oftentimes hit the nail more than just on the head; and whose bits were infinitely more than just satire. The guy was a comedian, satirist, begrudged philosopher, and even the narrative voice of Thomas the Train.
Look up what he said about the term "conspiracy theories".
Then match that with Simon's mockery, and you'll see something astonishing.
Also look up
'George Carlin tells his own biography'
He would have rejected all the labels you gave him.
He described himself as a
"writer who preforms his own material."
Filmore would approve
I used Carlin's comedy videos to help my teenage son realize the reality of - life in America, religion, people, and a plethora of other topics. He was the best!
That would be an AWESOME Biographic!
I still remember being young and watching random documentaries during downtime on a family holiday. Sky TV was a novelty so I was going through some weird new things, and came across one about ebola that scared the hell out of me. This virus that makes people bleed from every orifice and is almost 100% fatal, it was insane.
Years later, I came across an excellent documentary I highly recommend checking out. It can be hard to find, but IIRC it was named Ebola Syndrome and was released in 1996.
Always love a well informed piece on how humanity could have ended cheers biographics team keep up the vids 👍
One of my friends travelled to West Africa for working on a construction project. He then contracted malaria and was evacuated back to South Africa. A few days later, the Ebola outbreak started, which he fortunately missed.
BTW, South Africa is very far away from West Africa. At the time, many people asked on social media (like Quora) if it was safe to travel to South Africa in light of the Ebola outbreak in West Africa.
Yes, silly (and quite a shame) that so many people are ignorant of basic Geography. Then again, it doesn't seem too unreasonable to theorize it could be more likely to get a foothold in South Africa than, say, Luxembourg, Canada, Argentina or Iceland!
But anyway, what struck me as much more poignant is how silly it is that Ebola would even be on the radar at all for anyone considering whether or not it's safe to go to South Africa.....
No!
ABSOLUTELY NOT!
It's *never* "safe" to go to South Africa! (at least, not for most people, under most circumstances, and by most reasonable definitions of "safe").
Even if there _was_ an Ebola breakout there, comparable in scale to the worst there's ever been, it would still only rank somewhere around #19 on the list of reasons it's not safe to go to there.
Seriously, no one should _ever_ go there if they have any other choice at all; *it's a complete sh1te-h0le!*
But hey, I don't really have a strong opinion about the place one way or another 😁
I remember we made nervous jokes about it here in Cape Town.
Yea duh southafrica is litterally the south of africa. Also the entirety of africa is a shithole unfortunarely so it wouldnt be far from probable that a virus could ravage the entire continent
You should do one about John “Jack” Reed. An American journalist, author, and communist activist who witnessed the Russian Revolution and is one of 3 American communists to be buried at the Kremlin Wall Necropolis. And one interesting fact about his work is that it was so well detailed that it was eventually banned in the Soviet Union after Stalin came to power as it undermined Stalin’s narrative of the event.
I mean, they already did Huey Long, so that’d be another Kaiserreich character
@@PresidentAutumn I’ll admit that that is part of the reason why I would be interested in a video about Reed 😂
Cringe
That would be great, so that youngins can learn what horrors and injustice that communism brings upon the involved people.👍
@@BearBig70 You’d be surprised to know that he seriously opposed the dictatorship seen in what Stalin turned communism into. It’s why his works were banned in the Soviet Union when Stalin took over.
I recommend you read The hot zone by Richard Preston. It's worth it just for the chapter which describes what Ebola does to you from infection until death. It's a terrifying and horrific way to die.
You have no idea how long have I been waiting for your input on Ebola. Thank you sooooo much!
Love falling asleep to a video about a disease that makes you bleed out your eyes
(Forgive me for leaving out some details, my memory is pretty fuzzy) I remember my Geography teacher in school was involved with some charity working in West Africa. We once had the head the charity, an incredibly tall, smiley African man who gave a talk about his organisation. He shook each class members hands afterwards afterward (his hands were massive). After the Ebola crisis I remember hearing my teacher say that the charity was discontinued due to the crisis, saying something like "it was all for nothing".
What an awful, disrespectful, and ungrateful thing to say. It was not for nothing. Not in the moment when it bettered/saved lives. Not to those who survived the outbreak.
Imagine living such an easy life that you consider selfless and serious charity work dedicated towards those in desperate need for nothing cause it’s possible some or many of the recipients died.
Sorry but that just boils my blood
@@oppaloopa3698 the charity hadn't even started
work before ebola hit, and had very ambitious goals that it would tragically never achieve due to going bankrupted.
I don't consider charity work pointless, nothing in my comment indicated that I thought that. stop being irascible.
@@oppaloopa3698 wait what
@@kevinrwhooley9439
What your were trying to get across is that on top of the human life loss, the Ebola outbreak had devastating impact on economic and health care in an area in desperate need of both.
At least, that's what I'm gathering from your posts.
I read the Hot Zone many years ago and the one thing that always stuck out and kept me up at night, was how the one scientist didn't think it'd ever be a serious global threat because it *killed people too fast.*
And thats absolutely true, we 1. World inhabitants are safe
Honestly i feel so sad for those mourning the first dead in the funerals. Their traditions almost destroyed humanity. This is why being educated is so important. Imagine being sad and ignorant and killing your entire family because you didn’t believe it was a big deal.
Yea thats just africa dude
I heard that there are 5-6 variants of the dreaded Ebola virus in various parts of tropical Africa. I forgot the names of each of the variants, but the so-called "mildest" variant is fatal to approximately 60% of the victims who are infected, while the most severe form(s) is fatal to about 90% of the victims who become ill with it.
The ship that healthcare workers from the British military were housed on in the 2014 outbreak ended up being nicknamed the Ebola Gay. That’s about the only fun (and relevant) fact I can think of.
That's a good one
Lol
LMAOOO
I remember the 90s outbreaks… I was freaked out because no one really said if we could get it here in the US or not. All I remember is seeing people on the news being tossed into massive communal graves. It was sad and horrifying at the same time. I’m glad they finally found a way to treat this terrible virus. Maybe now the deaths will end.
One of my favorite books is "The Hot Zone " . Incredibly interesting and scary, because it was true !
I love this book it made paranoid but aware of others tragedies
I think I just need a permanent work from home job til I retire. Love how he calls it “Eboler”
He's well known for intrusive Rs mate 😂 does a bout a dozen per video which is concerning when he's just reading a script lol.
having a 2 minute long ad as soon as the video starts is probably a really bad decision lmao
When I was 12 while it was happening, I convinced myself that the Ebola virus would be the cause of the world ending
Man I remember this. My friend thought the world was about to end zombie apocalypse style and wouldn't hear otherwise for months. Weird times...
I remember back in 2014, my entire HS class was so invested with the Ebola virus and where it was spreading. We were thinking that it was gonna end up being a pandemic like with Covid once we heard someone from the US caught it.
I remember I was in fifth grade in 2014 & I lived in Namibia but I was certain the virus would take over the entire continent. I wrote a will as I sobbed, leaving my Barbie dolls, iPad and piggy bank to my favourite cousins, with strict instructions not to let my brother touch my stuff. I was a dramatic kid.
Very considerate of you to protect your brother and infect your cousins instead.
Nobody, and I mean NOBODY says the word “empire” like my man Simon. Pure class
I love how Simon looks like he's in pain while tasting athletic greens
I was a child in Germany when I came across an article in a paper telling about Ebola's attacking Marburg. The description of victims and symptoms was terrifying. Blood drained out of every orifice on the body.
This video makes me want to play "Plague Inc Evolved" again.
1:53 is when sponsored message ends.
Honestly, waiting for the West Nile Virus and Yellow Fever episodes. If Biographics continue doing diseases, both are very strong candidates.
If it’s someone’s hyper focus and they got nothing to correct, you got did an awesome job. Just like mine. I wanna specialize in Ebola and the imune system
I was in 8th grade in 2014 and had recently been diagnosed with severe anxiety but hadn’t yet been recommended for medication so I was tweaking out over this virus. I 100% believed the hoax about the man coming back to life after dying of Ebola and was convinced this was the beginning of the apocalypse (zombie or other). Considering how little I was scared about COVID (which was a considerably more likely virus for me to catch) and was able to just deal with it-I’d say my medication is working real well lol
I live down the road from Merck and, as a bartender, knew some of the sales reps and lab folks.
In 2014, they were bragging and laughing about finally being able to SELL - not PROVIDE - SELL the vaccine.
I understand it's a company and everyone needs to make money, but that disgusted me to no end.
I felt like Captain Picard in "Insurrection" - "HOW MANY PEOPLE DOES IT TAKE FOR THIS TO BE WRONG?!"
Great work team! So well researched 👍
Sponsor Skip for myself 2:03
legend
The Hot Zone is a fascinating/terrifying read.
ebola reminds me of when you level in plague inc every symptom
Post Viral Fatigue Syndrome was around long before Covid.
This disease scares not because of the way you die but the reaction some cdc workers where doing field work killed by paranoid locals. Convinced they were stealing and selling their blood. Meaning if something scarier deadlier appeared what would the public do in such a terrifying time.
"Should we do something about those huge bats living in our factory?"
"Nah."
"But they're defecating on us while we work, and it's pretty well known that nasty bugs can be found in bat guano."
"Eh, we're good."
Simon has done a few of these videos now and they're always interesting. Biographics is probably the best place for it at the moment, but I wouldn't be surprised if we see the launch of 'Diseasographics' one day!
Simon launches a new channel nearly every other week. You should charge him for naming rights
Future Video suggestion -
Eamon DeValera (1882-1975) - prominent political leader in 20th century Ireland who, after the Irish war of independence from 1919 to 1921, was in the public eye for over forty years from 1922 until his death were he served as head of government (Taoiseach) and head of state (president). He was nearly executed in the Easter Rising in 1916 and was key in putting into place the new constitution on 1937. A very prominent figure in Irish history.
I used to be terrified of this virus when the news hit back in 2014. But now I have faced that reality of how unlikely it is for people in the northern hemisphere (bless everyone) to have an incredibly low chance of catching this virus. Now I am more terrified of the brain eating ameoba and rabies. Both of which have appeared near me.
I've not watched yet, but YES! Nightmares! Ebola and C-diff, Shigatoxin, Cholera... anything that makes you just ooze out all your liquids through any orifice.
C diff does not do that. It just causes horrible foul smelling diarrhea, but it is nothing like ebola
I remember being in 7th grade when the 2014 virus happened and we watched a documentary over it. It terrified me then and it terrifies me now
Media overreaction as is so often the case. Ebola is indeed very dangerous. Fortunately however = it is not easily spread. To catch it you must come into contact with infected fluids from a person who is actively ill. Yet by that point the person is usually incapacitated or quickly will be. So you can not catch it sitting on a bus or moving about your daily life. The only way is via physical contact with actively ill people and/or their infected fluids. 🤔
Live in Botswana, Southern Africa and im glad we’ve never ever had such diseases or viruses
we have aids down here bro
I remember studying articles about the 2015 outbreak in my middle school science class. It was an interesting thing to learn about and honestly gave some perspective to my 6th grade self on just how lucky I was to be in a place where something like it struggled to take root. I can't imagine the sheer amount of suffering those infected had to experience.
The scariest disease in mankind's history for sure. I do still have some memories of the first Ebola outbreak. When the first time that heard around the world, it caused huge panic and concern.
No way. Rabies has been around for millenia and there are cases documented as early as the time of the ancient Greeks. Ebola, on the other hand, has only been documented in humans since 1976. The majority of mankind's history would have a little something to say about your claim.
@@johnnyvivic8730 i would say smallpox is history's scariest disease which makes its eradication so significant. in the 1800s 400 000 deaths a year in Europe alone can you imagine the death rate if a smallpox pandemic like covid 19 was to have happened? estimates show that 300-500 million people died from smallpox in the 20th century alone and it has killed billions of people throughout history and it has dated back to 1350bc. truly a scourge of humanity since the dawn of civilization.
@@Phantom-bh5ru Yes I agree. It is a great feat of mankind that smallpox has been eradicated.
Thank you Simon for all of your videos. I am very interested in virology and medical history and study these topics and you make it incredibly interesting. Thanks again xx
As a kid I was living in Libreville (Gabon) in 1994 when that ebola case started. The news at the time said that some villagers went hunting and brought back some chimps for dinner. Usually when the hunting party brings back some game meat, everyone in the village gets a share. So it was said that the chimp meat was shared among the villagers and they ate it (cooked, from what I understand). I believe many contracted the virus while preping the meat. What I do remember clearly was the disgust city folks in Libreville had for those "monkey eaters". It was a "why you gotta make us look bad??!" sort of situation. I left Gabon with my family before the outbreak was contained to go back to our home country (my dad had been promoted).
Long before the 1994 outbreak there were dozens of false news and fears about some ebola outbreaks in villages near the capital.
okay but eating chimps is objectively not ok.
@@peachoxo4099 honestly I don't know how some folks define meat lol. Out of the animals in that forest they decided on chimp.
I've been a vegetarian for decades and I don't understand - why is it weird to eat monkey meat? Is it because monkeys are clever? I can never understand the random differences between meat eater ethics. Some think it's fine to eat horses, some think it's awful, some think it's fine to eat dogs, some think it's awful, etc. Pigs are wildly intelligent but many people eat those. Its just so weird to me. Meat eaters will eat a lot of animals but then some random animal is 'going too far'. Like damn just stop killing and eating things with a brain altogether it's easy. And we'd have way less diseases lol
@@skunkjo3195 For me I wouldn't eat monkey meat for a couple of reasons, 1: they're too human 2: they carry a ton of diseases so it's better to not risk it
Proud to say I am the primary clinician in the clinical trial evaluating the Oxford vaccine against the sudan and zaire strain of the ebola virus in Tanzanian 😊
The British accent is what makes these videos (aside from the content). The clear diction makes the narration easy to follow and enjoy. And the personal vocal flair here and there also works.