Damn, he does his own research, pushes boundaries, sticks his neck out for what he believes AND supports people torrenting his own show. And people say there's no more real journalists
When I first started watching Hamilton's Pharmacopeia, I didn't know who he was and I thought that him reciting chemical compounds and processes during the montages was just a gimmick. I swiftly realized the man is a brilliant chemist. He literally synthesized a compound because he wanted to preserve a population of desert toads so people could get high sustainably without harming them. Wild. Edit: To everyone telling me how easy this synthesis is, I bet your Big Dick chemistry degree from Shitballs University was a breeze, it's incredible how many "chemists" come out of the woodwork when you compliment one on RUclips
As someone who has taken organic chemistry on the college level I can't discern whether he's a brilliant chemist. He could 100% have a good understanding of college level organic chemistry and give this kind of presentation. It doesn't make him a brilliant chemist. I'm not saying he's not, however. He could be. It's just that it's not obvious to me as someone with a college level understanding of orgo could present this way.
@@HexFent Ay bro, ScienceGuy actually has a really good point. I myself am doing a bachelors in Chem. and Hamilton sure does sound like he has some knowledge about chemistry but not to the level of a genius. You could probably give anybody an Alexander Shulgin book or even an intro chem textbook and if you regurgitate that information to a regular person with little chem knowledge, they'll think you're a genius too but when you have a background in chemistry, the stuff he speaks about is actually pretty basic. I think most people can understand the topics he brings up by spending a few hours reading up articles online or a textbook, nothing ground breaking enough to be considered a genius, but I will admit that he has more knowledge about it than the general populace.
@@NolieRavioli My guy, I was referring to how OP was saying he's a brilliant chemist. Neither me or scienceguy was saying that Hamilton is not a smart guy, just maybe not a brilliant CHEMIST, as we can't tell simply from the chemistry he uses in his videos and documentaries. So in this case, we really ARE talking about his knowledge in the "classical sense" since OP literally calls him a brilliant chemist. He is definitely a smart guy and I have been watching his stuff for years. Pay attention more, not everybody is out there to talk shit or to criticize, we aren't calling him out. I love his stuff and his knowledge/ability in transformative content far out stretches mine, I doubt I can make a documentary half as good as his, but calling him a genius chemist when he shows a reaction scheme (as an example) that he didn't write out himself even is a bit far fetched.
@@laurean5998 you don't need large amounts of methanol unless you want to make 10s or 100s of grams of the stuff. Considering the dose is around 5mg you wouldn't need much. But why do all that when you can just extract n,n-dmt, it's much simpler and a way better drug
@@coldwater5814 I once spent every other weekend for year smoking dmt I used to call it going to Narnia but stopped taking it because it felt like a lifetime before I returned back to this reality.
thats just so stupid, its literally the same chemical created without any frogs, believe in biology not spirits. After all that hard work these dumb minded spirit dimension believers... bruh
@@superlambmilkshake4904 to them it's a religion. It's basically the same as Catholics thinking that some bread that a dude in a wizard outfit cast a magic spell over is literally the flesh of Jesus Christ.
Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.
Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
Yes, dr.sporesss. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
I wish they were readily available in my place. Microdosing was my next plan of care for my husband. He is 59 & has so many mental health issues plus probable CTE & a TBI that left him in a coma 8 days. It's too late now I had to get a TPO as he's 6'6 300+ pound homicidal maniac. He's constantly talking about killing someone. He's violent. Anyone reading this Familiar w/ BPD know if it is common for an obsession with violence.
I loved the theory, but screwed up the practical. I could follow recipes to cooking classes, but not the steps in a lab. Going to have to do A LOT of research and relearning things before making DMT & changa this year.
@@bbloomfield6497 It's good to do research. Hamilton talks about it in his podcast with Eric Andre should check it out if u haven't. What he says is that he doesn't want to/can't put a step by step guide out there so people can't just follow how to do it like a recipe in a cook book. Good luck with your endeavour tho.
@Eternal悲嘆 I don't find Rogan to be a know it all. He'll even say he doesn't know what he's talking about. But it doesn't stop him from saying some dumb stuff. He's been really annoying lately though repeating stuff like you said. I'm so tired of hearing him talk about COVID
This chemical synthesis is the so-called reductive amination by the Eschweiler-Clarke reaction using 37% formaldehyde and conc. formic acid. 86%, the reaction has been modified by replacing formic acid as a hydride source with sodium cyanoborohydride (NaCNBH3). A solution of 5-methoxytryptophan in anhydrous or dry methanol (100% free of water) is added to the reaction balloon with an ice bath, then the 37% formaldehyde solution is placed in an addition funnel and in another addition funnel a solution of sodium cyanoborohydride dissolved in methanol or dry ether or tetrahydruphorane (THF), both solutions are added drop by drop with constant stirring determining that the temperature does not increase, it can be helped with a reflux condenser. Once the reaction is finished, the crude oil is separated from the 5-methoxytryptamine and a fractional distillation is carried out, the distilled psychotropic is re-purified by a simple distillation, it is crystallized by dissolving the psychotropic in methanol or toluene, the crystals are cooled and filtered. It can be obtained from melatonin by deacetylation carrying out a reaction under reflux with hydrochloric acid and neutralizing with sodium hydroxide until alkaline pH (7-9), the precipitate is filtered and the reductive amination is applied. I answer any question for academic purposes, good luck.
Old thread but 2 questions. 1. What is the formaldehyde in solution with? (The other 63%) 2. Here he is using Sodium borohydride not sodium cyanoborohydride, does it make a difference?
@@samuelsbald3038 both are good reducing agents, what happens is that sodium borohydride is much more reactive than sodium cyanoborohydride and is used more in reductive amination like the other, the difference is that sodium borohydride being stronger is capable of directly reducing formaldehyde to alcohol, while the other is not because it is less reactive, so that this does not happen, it is better to react the amino group with formaldehyde for 1 hour to form the imine, and then reduce it, but both are very good, you just have to keep that in mind.
Only a small mistake, but "5-methoxyTRYPTOPHAN" (5-meo-TP) is not the compound you would use for this synthesis, instead you would start with "5-methoxyTRYPTAMINE". 5-methoxytryptophan in this reaction would yield '5-methoxy n,n-dimethyltryptophan'. It is very very likely that this compound produces psychedelic effects, but has not been studied enough to be sure of that. If starting from 5-meo-TP a decarboxylation would have to be carried out first in order to yield 5-meo-T. You could use Lithium Aluminum Hydride (LiAlH3) as a reducing agent for this reaction. Then from here, you would have to purify the 5-meo-T via recrystalisation. With your 5-meo-T you could do a reductive amination by the Eschweiler Clarke reaction to yield 5-meo-dmt.
Hi Hamilton, I just finished my last year of high school, your documentaries and vice articles (especially the sea sponge one) have been a huge influence on my interest in chemistry. Although Covid cancelled many of my in class practical experiments, I have had a lot of fun creating various esters and interesting smelling compounds at home. Thanks for the inspiration and help introducing hobby chemistry to the masses.
Haha funny, that reminds me of myself, 10 years ago, when I was binge-watching UC235's and Nurdrage's videos on youtube. Im currently doing a PhD in organic chemistry. These videos have impacts on alot of lives!
@@asensniper oh man, Nurdrage is really what got me into chemistry and the like. I'm currently an undergrad doing chemical engineering and I credit almost all of my fascination to that guy and his videos. Plus NileRed as well. Good luck on your PhD!
louis would be observing Hamilton high on hallucinogenics asking the most rediculous questions, while Hamilton is observing Louis trying to figure out if Louis just produces his own acid on demand
Your show has played a big role in me wanting to research psychoactive compounds with my chemistry degree. I enjoy your work and especially love when you talk about chemistry on your show.
Same here! Hamilton's Pharmacopeia and Vice's series called the war on drugs has helped me become hugely interested in mental illnesses and drugs. Ive recently got an offer to study Pharmaceutical science for a degree and I can't wait
Macro vs Micro had success in doing a few Macro first . Allowing the mushrooms to blast you into self awareness , showing you the shadows and trauma that have been hiding under the rug . Micro dosing has helped me stay on the pulse of my shadow work , helping me remember my best self .
0:05 Microdosing makes me feel more human . I personally feel like microdosing increases my ADD for the day , but I may have to dial the dose down a little . The benefits outweigh the downsides .
This man is the reason i quitted my Art career and pursued Pharmaco chemistry instead. I can never thank you enough for inspiring me. Greetings from Peru.
Thats good. Artist thinks their art is good because they fully understand what they created, other people don't think the same. They will shit all over it because they don't understand but that doesn't mean its bad art. Im glad you choose this career
@the truth That's pretty petty of you. The commenter is intelligible and wrote with a level of grammar only slightly below the level that you used in your comment. In other news, congrats on your weight loss transformation. I cried at the last photo
Psychedelics definitely has potential to deal with health issues like anxiety and depression , I would like to try them but it's hard to source them here,
proven very effective in the treatment of various mental health issues aside from other health benefits. Helped me get out of years of depression and excessive alcohol use.
@@kathleenmcclenahan5701 I really get happy anytime I see people talking about Dr jackshroom, he is the best All pure psychedelic and shrooms I get from him
@@czlenson888 1) The plant you're referring to is called mimosa hostilis (not misosa), it mostly contains N,N-dimethyltryptamine (DMT), which can be extracted using an acid base extraction, (which is essentially what you're describing). 2) But what Hamilton is synthesizing here is 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), which is not the same substance as DMT, and not present in Mimosa hostilis in any useful quantities.
He uses a lot of fancy chemistry terms. But all you would really need is the starting chemicals, about $100 worth of glassware, and maybe a hot plate and the patience to start all over if you don't get it right. Google some of the chemistry terms then it's basically like baking a cake.
He talked about that on a podcast recently. He intentionally leaves out small bits of information so that your average layman can not figure out how to do this from only watching the video
@@111lillkiller really just a summary video here, but the info is out there, you just have develop the skills and acquire the necessary equipment. You don't need everything that he used, but it helps. Both in time and stress.
You can find a synthesis for virtually any drug online. It's just that most people don't have a masters in chemistry nor do they have the lab products needed.
I can't find a source anywhere for any good psylocybin in my area , I suffer some pretty bad depression and i got a chance to try K and man it was a miracle substance , I felt free , the only high or euphoria was from the relief of my vices being released , that's exactly what it did
Hi, I'll subscribe to you only if you can promise me that you'll replicate this exact recipe and record the whole process. Sincerely, someon who knows what he wants.
Hamilton is my great inspiration. He said it and done it. After his Bufo experience in mexico, he said "The availability of the toad is less and the need is more, so it has to be created synthetically". And he did it 🎉🎉🎉
Must feel pretty good to be pinned my Hamilton! It is so true, Hamilton is a great roll model. It's minds like his that will take us into a happier and healthier future for both us and nature.
@@vivindurkash definitely so i love how he's not scared to take risks and push the envelope of science further. If there were not minds like his we would still be in the stone age of chemistry and how it interacts with our brains and bodys. To me there's no question if we have receptors for various chemical structures that's built in us and those chemicals structures are around us naturally how can that not be meant for us to interact with in some way, shape or form!
people been synthinsizing for a long time. this is basically the only way to get it. dark/grey markets,, etc. no i havent tried it yet. this one scares me lol
I became OBSESSED with this video. Everything is great: the subject, the science, the music with that editing, the tone with which it's realized. Great job!! ❤
Thought this may interest anyone it's a story of my dmt cartridge experience :). So about 6 hits into the cartridge eyes closed I feel as if my mind now has became almost a painting that's been turned on but not fully activated. Space itself was flashing in my mind like if I was blinking inside my mind but every time a new brief image of galaxies stars etc appeared. And I could feel it with 100% of my senses those I didint quite even understand lol. As the body high increased with my hits I began to notice a feeling as if a thin "Soul" was being flashed out of my body and it was telling me this for certain when I came into a realm of beautiful darkness highlighted by a dark "wall" of deep deep tunnels with rims resembling black holes with rainbow chromish edges. I then felt the intensity of a specific tunnel and could feel its depth before I even went inside but when I did I was transported to a world where I looked at a bigger version of myself cut in half with living mechanical gears perfectly in place like a puzzle in my brain and other organs. And then as I became one with this creation in another flash I was flying through a rainbow tornado on an earth type planet but the clouds blocked my vision of most of that planet pretty sure 😭.
@Alpha Centauri it was from a good vendor off White House market and since it was a cartridge I've heard they usually take more hits then normal dmt itself to breakthrough. For example I used my gpen connect with 55mg and it hit me like instantly
Use White House market and use changelly to convert btc too xmr 👍😋. Use vendors only from your country for any products tho dmt is generally a lot safer to ship especially in smaller amounts if the vendor is good
The extraction methods that previous commenters mention is for N,N-DMT, which is slightly different than the 5-MeO-DMT we see Hamilton synthesizing here. Both are some of (if not the) strongest psychedelic substances we know of at this time, but from what I've read, 5-MeO is generally regarded as more intense than N,N (I've only done N,N, so I can't attest to this, personally). The extraction process for N,N-DMT is fairly straightforward, but as with all things dealing with chemicals, should be treated with respect and precaution.
That guy actually got hold of a mic and rambled for several minutes about nothing in particular and ended his spiel by saying he believes we create 5-MEO-DMT from melatonin inside our brains.
Hamilton! My crown chakra is tingling. A little over a week ago RUclips took me on a binge of your previous adventures of experiencing this eyeblink of us seeing light bending in different ways and now I see your channel pop out of nowhere. The algorithm has been pleased and so am I. ❤️
God damn this dude as smart as hell I would love to have a friend that is good at chemistry like this dude.. but I honestly think he's on a whole another level.
Hi Hamilton I hope you get to read this as I have been watching your videos across the internet since you began on Vice, and you've inspired me to do chemistry at college, currently studying Pharmaceutical and Medicinal Science in Ireland in my final 4th year! and without the passion and interest you have shown for chemistry I would have never done it. Lots of people make it out to be difficult yet I find it extremely interesting with that helping me learn much more, just wanted to say I'm so grateful even though you don't realize how much you've inspired me and other people. I would love study psychoactive compounds in the future thanks to all your work as well. Hope your good and maybe some day we will meet eachother! Thanks, Conal
I've watched this video like 29 times or more idk it's so many I just love the music and I get some kinda ASMR effect or something from hearing Hamilton talk about chemistry lol.
I just finished my second semester of organic chemistry at GVSU. I happened upon your show a few months in to my 1st semester last year and watched every episode, it's rewarding to be able to understand (for the most part) the many mechanisms discussed in the reactions in your show. Additionally, it's amazing how ultimately all the complex and enigmatic psychoactive effects from these compounds boil down to the infinitesimal transfer of electrons. I think this show is giving many young people the spark, the inspiration they need to fuel their passion for learning science, and it is bringing light to the wondrous field of chemistry.
this is probably the most intense and overwhelming psychedelic i have ever tried. i have a massive amount of respect for this substance and it should be used with a shaman or someone who knows what they are doing.
I only know nn dmt and I strongly suggest some serious preparation before embarking. 5meo is said to be even stronger so even more precaution should be taken.
I agree - after several 5-MEO experiences over the years, there are no words can remotely describe the experience . Only respect and awe for this amazing tryptamine.
The real deal don’t hurt the toads they sing songs to them and the toad give the dmt to them naturally. No need to hurt the little fellas. Some people don’t understand this method they think it’s crazy lol they ain’t done it
@@alanspencer6417 just leave them toads alone... habitat destruction, animal slavery, etc... not a good look for getting a drug. and not to be pedantic, but for safety's sake, it is important to note the distinction between 5-meo-dmt and dmt. they are different drugs with different potencies, different fx, and different safety profiles.
hamilton, I want to thank you for inspiring me to return to chemistry as I’ve failed (numerous times) previously and had lost all motivation to study it. thank you. your explanations are second to none and you are one of our generation’s greats.
If chemistry isn't your thing, there's lots of other areas to drugs that aren't covered in depth. There's neuroscience, metabolism, history, side effects, etc that are all still need documentation. :)
Please don't tell your kids a false narrative. He is nothing like the Heisenberg in Breaking Bad, which I assume you're reffering to, due to the position of "the real Heisenberg" being already occupied by an actual historic person that is know to have been a brilliant theoretical physicist. If you compare Hamilton approach towards sharing knowledge to a rather ruthless druglord that acts mostly out of selfinterest, your perception of reality seems upside down to me..
@@mrsinger5539 Ye, I get that this was his/her intention.. it's just that I had to think about it for less than the glance it took to me to read in order to shake my head in disappointment due to the lack of attachment to reality, which I tried to point out in my comment.. I don't wanna start a useless argument on Hamiltons Channel thou, so peace out an laugh about w/e you like, just don't cry because someone states your humor is off/trash.. :P
Reductive Amination: the clandestine chemist's favorite reaction. It would be pretty neat to see the synthesis of 5-MeO-tryptamine from melatonin by hydrolysis, since said precursor is extremely expensive from chemical suppliers and requires the typical business license.
you can deacetylate it with naoh solution , heat to 105c in isobutanol for a few hours reduce the solvent down 50% , add 10% acetone and freeze it, youll get a bunch of good crystals , you can repeat it to scavenge the rest of the mexamine from solution on a second crystallization.
I was involved with a vivacious group of people in the early 2000s that ran a true clandestine LSD lab I was dating a woman who's brother was a organic chemist at the University of Washington at the time we all lived in the "U" district and it was the most compelling time of my life. Long story short I agreed to be the fall guy when the feds were tipped off they ransacked the house found only a few legal precursor chems a 40 bag of weed. What they didn't even realize is that on the wall there was a 48x30 self portrait of van gogh made of pure blotter it was mostly inert due to light, oxygen exposure but goddamn what a wild ride I wish there were time machines! Happiness to everyone and peace!
Same DMT/related compounds are life savers. I hope this can become more available to those who need it soon. Was not easy to obtain here in Canada (I don't trust street sources.)
@@ME-ol9gk Id wager you could quite easily obtain it over the darknet, but this is obviously very illegal. However, it's usually such a small amount of substance it would be virtually almost impossible to detect amongst the thousands of other packages. Mine came packed in between a deck of playing cards. Maybe you could consider trying mushrooms. I've no clue what the UK is like but they must be easier to obtain than DMT there.
@@ME-ol9gk I believe there are comprehensive resources on Reddit available to guide you. It's relatively safe to use the darknet when you follow directions carefully. I personally had spent thousands in the past with out issue.
@@chigbungus5257 Psychedelics like psilocybin, DMT, LSD etc. tend to affect your sense of self; your ego, the 'voice in your head.' Altering or obliterating that voice, even temporarily, can be risky. Depending on your starting point (and few really are so self-aware that they know themselves that deeply), you cannot be sure if the change will be one you want or can live with easily. Those that find it positive and magical sing it's praises, but less often heard are those that do not come back, and instead trigger a latent psychosis or other negative effect.
@@commentatron less heard about?? The fuck you on about? Prior to 2020 80% of what you heard about this substances was about the risk of triggering schizophrenia or pther mental disorders.. If you dont know that this shit comes with a risk its tour fault the information is out there.
Nice video but the mecanism he gives is kinda wrong, he's suggesting a cationic protonated alcohol leaving group during his reductive amination. You're never gonna form that in the presense of sodium borohydride (H-). Sorry, annoying O-chem PhD here :D
I watched this a few years ago and it made no sense to me but I went to university to study chemistry and now it kinda makes sense! Except for the borohydride part, I haven't seen that before.
You're amazing. Keep doing your thing. For some reason when I saw the cuts to you eating a banana after talking about the synthesis, I thought about how much perspective matters. You're doing amazing things with chemistry, and then you cut to eating a simple banana. When I personally thought about it, I thought that both scenes are incredible in their own right. Obviously you synthesizing 5-meo-dmt, but also just how amazing it is that we're here and have bananas to eat. Depending on your perspective at the moment, both could seem uninteresting and dull. But another perspective could be that both are equally amazing. Im rambling, if you read this far have a good night. P.s. if you've got a dog, give them some love now!
Hey Hamilton, I have been watching your experiments for a while now and I can say I am very impressed! I was wondering if you are willing to continue your research on the synthesis of tryptamine derivatives. The 5-MeO-tryptamine as a starting material is not accessible to a lot of chemists and industries around the world. How about the complete synthesis of DMT or other useful tryptamines from an indole or tryptophan as a starting material? The literature is very old and with a lot of mistakes. Kind regards, I Love your work!
Bro, save the frogs. I didn't know you had a youtube channel, watched all your pharmacopeia episodes. Instantly liked, favourited subscribed and bell notified all. Hell yeah Hamilton.
For those who want to do further research on this reaction, this is the Eschweiler-Clarke reaction, which is used for the selective n-methylation of primary and secondary amines. But the reaction traditionally uses highly concentrated formic acid instead of sodium borohydride.
Damn, he does his own research, pushes boundaries, sticks his neck out for what he believes AND supports people torrenting his own show. And people say there's no more real journalists
And he doesn't even consider himself a journalist. They're just labels to quickly neatly fit people in boxes
yes I
@Dirk Diggler oh no :( i loved the series and Hamilton!
@Dirk Diggler source?
@Dirk Diggler If only they made the show available worldwide legally.. there's literally no way for me to pay to watch it.
“It’s a controlled substance in the United States.....but I’m in Mexico” lmao
You Boys Ever Been To Meheekho!?
Lol I didn’t think he was serious at first too
@Who Cares im freaking out, man
@@P3GProductions the schnozberries taste like schnozberries?
I'm pretty sure I got it, though if I'm correct it's over forty years since I read the book.
as a chemist i have to say - that was such an incredibly beautiful lab hamilton was working in!! so jealous!!
Do you know what that thing was called that he had the 3 addition funnels connected to?
@@williambeasley6448 a 3 neck round bottom flask?
@@danr5496 nice man thank you I just googled it and I found a 1000ml one for $23 ✌😎👍
@@williambeasley6448 Did you ever try and make this DMT?
@@nataliep6385 thats a question only a dumbass would say yes to a random stranger so double no
When I first started watching Hamilton's Pharmacopeia, I didn't know who he was and I thought that him reciting chemical compounds and processes during the montages was just a gimmick. I swiftly realized the man is a brilliant chemist. He literally synthesized a compound because he wanted to preserve a population of desert toads so people could get high sustainably without harming them. Wild.
Edit: To everyone telling me how easy this synthesis is, I bet your Big Dick chemistry degree from Shitballs University was a breeze, it's incredible how many "chemists" come out of the woodwork when you compliment one on RUclips
Yup, judging people for using big words is absolutely absurd.
As someone who has taken organic chemistry on the college level I can't discern whether he's a brilliant chemist. He could 100% have a good understanding of college level organic chemistry and give this kind of presentation. It doesn't make him a brilliant chemist. I'm not saying he's not, however. He could be. It's just that it's not obvious to me as someone with a college level understanding of orgo could present this way.
@@HexFent Ay bro, ScienceGuy actually has a really good point. I myself am doing a bachelors in Chem. and Hamilton sure does sound like he has some knowledge about chemistry but not to the level of a genius. You could probably give anybody an Alexander Shulgin book or even an intro chem textbook and if you regurgitate that information to a regular person with little chem knowledge, they'll think you're a genius too but when you have a background in chemistry, the stuff he speaks about is actually pretty basic.
I think most people can understand the topics he brings up by spending a few hours reading up articles online or a textbook, nothing ground breaking enough to be considered a genius, but I will admit that he has more knowledge about it than the general populace.
^watch more of his material
@@NolieRavioli My guy, I was referring to how OP was saying he's a brilliant chemist. Neither me or scienceguy was saying that Hamilton is not a smart guy, just maybe not a brilliant CHEMIST, as we can't tell simply from the chemistry he uses in his videos and documentaries. So in this case, we really ARE talking about his knowledge in the "classical sense" since OP literally calls him a brilliant chemist.
He is definitely a smart guy and I have been watching his stuff for years. Pay attention more, not everybody is out there to talk shit or to criticize, we aren't calling him out. I love his stuff and his knowledge/ability in transformative content far out stretches mine, I doubt I can make a documentary half as good as his, but calling him a genius chemist when he shows a reaction scheme (as an example) that he didn't write out himself even is a bit far fetched.
Hamilton: "Any questions?"
The hippie in the audience: "Dude can I get some?"
I'm not sure there's anyone there who isn't a hippie... lol
Yeah 'chemistry really interests me😉
3:36
@@ripme6616 haha same
In the actual episode the hippie stands up, and disagrees with the synthetization of dmt.
Joe Rogan: Jamie, write that down, write that down!
Picturing Spongebob and Patrick meme
😂
The Wizard was on stage my g.
@@ScholarOfBabylon Excuse me? 😂
@@ellis3320 You are excused my son.
Anyone can easily make this at home!
*Pulls out a lab*
Pulls out a high grade pharmaceutical precision lab and a vast amount of compounds.
@Anon proof
@Anon I wouldn't want large amounts of methanol evaporating in my kitchen...
@@laurean5998 you don't need large amounts of methanol unless you want to make 10s or 100s of grams of the stuff. Considering the dose is around 5mg you wouldn't need much.
But why do all that when you can just extract n,n-dmt, it's much simpler and a way better drug
@@Fractoide your right. Now that I think about it the amount of dmt he synthesized there is pretty ridiculous.
Friend: How was your trip to Mexico?
Him: How are you still alive bro, I've been gone for 6000 years.
Haha, I know what you mean..
But it's more like 6000 eternities..
👍👍
Does dmt do that? Heard it can make you live a whole life
@@coldwater5814 no
@@coldwater5814 I once spent every other weekend for year smoking dmt I used to call it going to Narnia but stopped taking it because it felt like a lifetime before I returned back to this reality.
@Derek Dunaway You literally look like a federal agent and your comment comes off as one too.
And then he opens up for questions and the audience immediately rips him apart because "synthesized DMT can't recreate the spirit of the toad, maaaan"
Yeah, that was incredibly depressing to watch
thats just so stupid, its literally the same chemical created without any frogs, believe in biology not spirits. After all that hard work these dumb minded spirit dimension believers... bruh
@@superlambmilkshake4904 to them it's a religion. It's basically the same as Catholics thinking that some bread that a dude in a wizard outfit cast a magic spell over is literally the flesh of Jesus Christ.
@@Beanpapac15 lmaoo
Still a better psycho-to-normal ratio than CSPAN Q&A
There seems to be a wizard in your audience
Hey dudes
I'm here too.
and there seems to be a nonce in his comments
I would love some DMT but don’t have a clue where to find it
high
I overcame my addiction with the help of mushrooms.
Psychedelics are just an exceptional mental health breakthrough. It's quite fascinating how effective they are against depression and anxiety. Saved my life.
Can you help with the reliable source I would really appreciate it. Many people talk about mushrooms and psychedelics but nobody talks about where to get them. Very hard to get a reliable source here in Australia. Really need!
Yes, dr.sporesss. I have the same experience with anxiety, depression, PTSD and addiction and Mushrooms definitely made a huge huge difference to why am clean today.
I wish they were readily available in my place.
Microdosing was my next plan of care for my husband. He is 59 & has so many mental health issues plus probable CTE & a TBI that left him in a coma 8 days. It's too late now I had to get a TPO as he's 6'6 300+ pound homicidal maniac.
He's constantly talking about killing someone.
He's violent. Anyone reading this Familiar w/ BPD know if it is common for an obsession with violence.
Is he on instagram?
Yes he is. dr.sporesss
If your show existed when I was in high school I would have had way more interest in chemistry, I hope a lot of young people get inspired by this
I loved the theory, but screwed up the practical. I could follow recipes to cooking classes, but not the steps in a lab. Going to have to do A LOT of research and relearning things before making DMT & changa this year.
@@bbloomfield6497 It's good to do research. Hamilton talks about it in his podcast with Eric Andre should check it out if u haven't. What he says is that he doesn't want to/can't put a step by step guide out there so people can't just follow how to do it like a recipe in a cook book. Good luck with your endeavour tho.
@Sean MRS Depends on your capabilities and drive. Nice to see there are still such assholes on youtube comments, though.
It's very easy to extract real Dmt. As long As you can get the roots you need....
Friend, I’m thirty-five and inspired by this. Enrolling back in school for chemistry in the fall.
I’m really hoping Hamilton goes on Rogan again soon to promote the new season! I need another 3-4 hour Hamilton podcast!! 🤞🏻🤞🏻🤞🏻🤞🏻
Hell yes.
yeah boi
yeahhh pls
@Eternal悲嘆 nocap
@Eternal悲嘆 I don't find Rogan to be a know it all. He'll even say he doesn't know what he's talking about. But it doesn't stop him from saying some dumb stuff. He's been really annoying lately though repeating stuff like you said. I'm so tired of hearing him talk about COVID
This chemical synthesis is the so-called reductive amination by the Eschweiler-Clarke reaction using 37% formaldehyde and conc. formic acid. 86%, the reaction has been modified by replacing formic acid as a hydride source with sodium cyanoborohydride (NaCNBH3). A solution of 5-methoxytryptophan in anhydrous or dry methanol (100% free of water) is added to the reaction balloon with an ice bath, then the 37% formaldehyde solution is placed in an addition funnel and in another addition funnel a solution of sodium cyanoborohydride dissolved in methanol or dry ether or tetrahydruphorane (THF), both solutions are added drop by drop with constant stirring determining that the temperature does not increase, it can be helped with a reflux condenser. Once the reaction is finished, the crude oil is separated from the 5-methoxytryptamine and a fractional distillation is carried out, the distilled psychotropic is re-purified by a simple distillation, it is crystallized by dissolving the psychotropic in methanol or toluene, the crystals are cooled and filtered. It can be obtained from melatonin by deacetylation carrying out a reaction under reflux with hydrochloric acid and neutralizing with sodium hydroxide until alkaline pH (7-9), the precipitate is filtered and the reductive amination is applied.
I answer any question for academic purposes, good luck.
How can one reach you?
Old thread but 2 questions.
1. What is the formaldehyde in solution with? (The other 63%)
2. Here he is using Sodium borohydride not sodium cyanoborohydride, does it make a difference?
@@samuelsbald3038 both are good reducing agents, what happens is that sodium borohydride is much more reactive than sodium cyanoborohydride and is used more in reductive amination like the other, the difference is that sodium borohydride being stronger is capable of directly reducing formaldehyde to alcohol, while the other is not because it is less reactive, so that this does not happen, it is better to react the amino group with formaldehyde for 1 hour to form the imine, and then reduce it, but both are very good, you just have to keep that in mind.
THF is the superior solvent for this reaction.
Only a small mistake, but "5-methoxyTRYPTOPHAN" (5-meo-TP) is not the compound you would use for this synthesis, instead you would start with "5-methoxyTRYPTAMINE". 5-methoxytryptophan in this reaction would yield '5-methoxy n,n-dimethyltryptophan'. It is very very likely that this compound produces psychedelic effects, but has not been studied enough to be sure of that.
If starting from 5-meo-TP a decarboxylation would have to be carried out first in order to yield 5-meo-T. You could use Lithium Aluminum Hydride (LiAlH3) as a reducing agent for this reaction. Then from here, you would have to purify the 5-meo-T via recrystalisation. With your 5-meo-T you could do a reductive amination by the Eschweiler Clarke reaction to yield 5-meo-dmt.
Hi Hamilton, I just finished my last year of high school, your documentaries and vice articles (especially the sea sponge one) have been a huge influence on my interest in chemistry. Although Covid cancelled many of my in class practical experiments, I have had a lot of fun creating various esters and interesting smelling compounds at home. Thanks for the inspiration and help introducing hobby chemistry to the masses.
I definitely wish I had Hamilton's videos 10 years ago!!!!
Haha funny, that reminds me of myself, 10 years ago, when I was binge-watching UC235's and Nurdrage's videos on youtube. Im currently doing a PhD in organic chemistry. These videos have impacts on alot of lives!
@@asensniper oh man, Nurdrage is really what got me into chemistry and the like. I'm currently an undergrad doing chemical engineering and I credit almost all of my fascination to that guy and his videos. Plus NileRed as well. Good luck on your PhD!
@@acurry8569 whats the biggest difference between the job field chemsitry and chemical engineering have??
@@Nicefail87 he was a bum and then he got inspiration to get a higher education you prick
Louis Theroux’s had a productive lockdown then
There's a crossover I'd love to see xD
louis would be observing Hamilton high on hallucinogenics asking the most rediculous questions, while Hamilton is observing Louis trying to figure out if Louis just produces his own acid on demand
😅
these jews tho
🤣🤣 welll now
I knew Organic Chemistry wasn’t completely useless.
Orgo 1-2-3 & Biomolecular Engineering 1-2 def some valuable systems
XD
why would anyone ever think its useless? you literally survive because of it
@@user-tr2dh4xx6u how does he survive by knowing organic chemistry?
@@user-tr2dh4xx6u do not feed the NPC
Save the Toads
indeed
Toad lives matter
+
skskskkskksk
Factoids
Your show has played a big role in me wanting to research psychoactive compounds with my chemistry degree. I enjoy your work and especially love when you talk about chemistry on your show.
Same here! Hamilton's Pharmacopeia and Vice's series called the war on drugs has helped me become hugely interested in mental illnesses and drugs. Ive recently got an offer to study Pharmaceutical science for a degree and I can't wait
@@voraciousfred Not yet but I will get to it eventually
Methoxetamine
enjoy rehab addict
@@sparklesparklesparkle6318 ?
Macro vs Micro had success in doing a few Macro first . Allowing the mushrooms to blast you into self awareness , showing you the shadows and trauma that have been hiding under the rug . Micro dosing has helped me stay on the pulse of my shadow work , helping me remember my best self .
0:05 Microdosing makes me feel more human . I personally feel like microdosing increases my ADD for the day , but I may have to dial the dose down a little . The benefits outweigh the downsides .
@Peterparker-wl7lnWhat's the difference macro and micro sounds exciting and I'll love to try where can I get them ? 0:25
@@marshalpetersdr.johnsonshroom is your guy. Best shrooms and psychedelics guy I know. 0:06
0:04 @@HudsonJayIs he on inst? I've been looking to get some dmt & acid. 0:04
@@JeniferChristian-xw3bn
Sure, dr.johnsonshroom 0:04
This man is the reason i quitted my Art career and pursued Pharmaco chemistry instead. I can never thank you enough for inspiring me. Greetings from Peru.
Thats good. Artist thinks their art is good because they fully understand what they created, other people don't think the same. They will shit all over it because they don't understand but that doesn't mean its bad art. Im glad you choose this career
@the truth That's pretty petty of you. The commenter is intelligible and wrote with a level of grammar only slightly below the level that you used in your comment.
In other news, congrats on your weight loss transformation. I cried at the last photo
@the truth Says the person who cant type himself
@@bredonheh4473 thanks for the unwanted bashing of art lol
Art is one of the most important things in human history
@the truth English is supposed to be capitalized. They taught that somewhere around second grade.
Psychedelics definitely has potential to deal with health issues like anxiety and depression , I would like to try them but it's hard to source them here,
proven very effective in the treatment of various mental health issues aside from other health benefits. Helped me get out of years of depression and excessive alcohol use.
@@kathleenmcclenahan5701How can I locate him? If he's on IG?
@@juttaclemons5002 Yes he's dr.jeffshroom
@@kathleenmcclenahan5701 I really get happy anytime I see people talking about Dr jackshroom, he is the best All pure psychedelic and shrooms I get from him
@@cathywalton1062DMT was the best trip I had though my first time was crazy but the second experience was amazing .
"vigorous magnetic stirring"
Me: oh yeah stir that shit
hehe you laugh but that's proper scientific language, a lot of reactions need to be stirred vigorously
@@origamigek proper words would be , controlled stirring ,, not to fast - not to slow,, The word "vigorous" just tells you the narrator's level 😉
Me seeing this video; YES I CAN MAKE SOME
Me watching the video: yeaaaah maybe not.
Just study the process one step at a time. Anything is possible if you put your mind to it ;)
There is a simple way to extract it using just misosa hostilis dryblend, parrafin oil and sodium hydroxide. Bucket science.
@@czlenson888 1) The plant you're referring to is called mimosa hostilis (not misosa), it mostly contains N,N-dimethyltryptamine (DMT), which can be extracted using an acid base extraction, (which is essentially what you're describing).
2) But what Hamilton is synthesizing here is 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), which is not the same substance as DMT, and not present in Mimosa hostilis in any useful quantities.
He uses a lot of fancy chemistry terms. But all you would really need is the starting chemicals, about $100 worth of glassware, and maybe a hot plate and the patience to start all over if you don't get it right. Google some of the chemistry terms then it's basically like baking a cake.
There are simple ways.
I love how precise this is, like "here is your recipe"
Recipe
REcipe
He talked about that on a podcast recently. He intentionally leaves out small bits of information so that your average layman can not figure out how to do this from only watching the video
@@111lillkiller really just a summary video here, but the info is out there, you just have develop the skills and acquire the necessary equipment. You don't need everything that he used, but it helps. Both in time and stress.
You can find a synthesis for virtually any drug online. It's just that most people don't have a masters in chemistry nor do they have the lab products needed.
Psilocybin, LSD, shrooms and ketamine are absolutely life changing substances that have so much potential to help people with mental health issues.
I can't find a source anywhere for any good psylocybin in my area , I suffer some pretty bad depression and i got a chance to try K and man it was a miracle substance , I felt free , the only high or euphoria was from the relief of my vices being released , that's exactly what it did
@@AnthonyLarsyes he's dr.jeffshroom 😍
@@ThomasBurlson-m5ryeah , he's got magic mushrooms , DMT , LSD and other psychs
@@AmadaBlackTripping is not a bad idea but it shouldn't be abused
@@AmadaBlackwhere can I locate him? If he's on IG??
Wow, Thank you 🙏 I will promote your method.
Great work as always 🙌 greetings from México
Te van a multar
A huevo tripi! Y Hamilton, gracias por todo!!!!
Alex Trip in the house 😂
Tripi vamos a trabajar juntos a un proyecto
Hi, I'll subscribe to you only if you can promise me that you'll replicate this exact recipe and record the whole process.
Sincerely, someon who knows what he wants.
Is it just me or does anyone else love watching saturated aqueous solutions percipitate?
timelapses on crystalisation are amazing too
Hell, I’ll take a drop-wise addition in a pinch.
Our brains as designed to recognise patterns. This is the beauty of life. /r/oddlysatisfying
Hey you ever seen a Belousov-Zhabotinsky reaction? m.ruclips.net/video/LL3kVtc-4vY/видео.html
An oscillating reaction of red and blue. 🙌
I’m just here for the food😉🥳🥞✌️
Have been following you for nearly a decade . . . You Sir are just an angel
Hamilton is my great inspiration. He said it and done it. After his Bufo experience in mexico, he said "The availability of the toad is less and the need is more, so it has to be created synthetically". And he did it 🎉🎉🎉
Must feel pretty good to be pinned my Hamilton! It is so true, Hamilton is a great roll model. It's minds like his that will take us into a happier and healthier future for both us and nature.
@@murderWhornets Agreed. I feel honoured, to get my comment pinned by Hamilton. I love his appealing mindset.
@@vivindurkash definitely so i love how he's not scared to take risks and push the envelope of science further. If there were not minds like his we would still be in the stone age of chemistry and how it interacts with our brains and bodys. To me there's no question if we have receptors for various chemical structures that's built in us and those chemicals structures are around us naturally how can that not be meant for us to interact with in some way, shape or form!
people been synthinsizing for a long time. this is basically the only way to get it. dark/grey markets,, etc.
no i havent tried it yet. this one scares me lol
@@vivindurkash not pinned anymore rip
Wow, this is like, bachelor's level chemistry techniques. This seems really approachable and doable on a large scale for workers, amazing.
Yes, it's actually pretty simple, a one-step synthesis.
One step one pot, I like it a lot!@@HamiltonMorris
If Hamilton goes missing, he’s probably locked in an underground lab owned by Joe Rogan
I became OBSESSED with this video. Everything is great: the subject, the science, the music with that editing, the tone with which it's realized. Great job!! ❤
the tiny bits of humor
Thought this may interest anyone it's a story of my dmt cartridge experience :). So about 6 hits into the cartridge eyes closed I feel as if my mind now has became almost a painting that's been turned on but not fully activated. Space itself was flashing in my mind like if I was blinking inside my mind but every time a new brief image of galaxies stars etc appeared. And I could feel it with 100% of my senses those I didint quite even understand lol. As the body high increased with my hits I began to notice a feeling as if a thin "Soul" was being flashed out of my body and it was telling me this for certain when I came into a realm of beautiful darkness highlighted by a dark "wall" of deep deep tunnels with rims resembling black holes with rainbow chromish edges. I then felt the intensity of a specific tunnel and could feel its depth before I even went inside but when I did I was transported to a world where I looked at a bigger version of myself cut in half with living mechanical gears perfectly in place like a puzzle in my brain and other organs. And then as I became one with this creation in another flash I was flying through a rainbow tornado on an earth type planet but the clouds blocked my vision of most of that planet pretty sure 😭.
Trip reports don't belong here, make a video thanks 😉
@Alpha Centauri it was from a good vendor off White House market and since it was a cartridge I've heard they usually take more hits then normal dmt itself to breakthrough. For example I used my gpen connect with 55mg and it hit me like instantly
this video isn't even about that drug.
@@yamilbermudez73 Uh...this is the comments section, anything belongs here.
@@yamilbermudez73 you can’t say that on a video about DMT lol of course these stories are welcomed
Fucking Hamilton, what a Goat. Only he could illegally make something "legal" all just for our entertainment and his own experimenting. 💯💯💯
Starts watching: I can make DMT by myself at home??? Awesome.
Keeps watching: Oh, I need an industrial laboratory...
No you don't
Use White House market and use changelly to convert btc too xmr 👍😋. Use vendors only from your country for any products tho dmt is generally a lot safer to ship especially in smaller amounts if the vendor is good
dmt is very easy to extract at home by urself
The extraction methods that previous commenters mention is for N,N-DMT, which is slightly different than the 5-MeO-DMT we see Hamilton synthesizing here. Both are some of (if not the) strongest psychedelic substances we know of at this time, but from what I've read, 5-MeO is generally regarded as more intense than N,N (I've only done N,N, so I can't attest to this, personally). The extraction process for N,N-DMT is fairly straightforward, but as with all things dealing with chemicals, should be treated with respect and precaution.
@Russell Dent There is a difference between extracted n.n-DMT and 5-MeO-DMT, which is the subject here.
He needs to re do this video in a shed using plastic bottles and duct tape
Be the hero of your own story cowboy
The final product: Jenkem
The hippie at the end "Not right now but I'm gonna find you after the conference. lol
That guy actually got hold of a mic and rambled for several minutes about nothing in particular and ended his spiel by saying he believes we create 5-MEO-DMT from melatonin inside our brains.
I think he had a lot invested in them toads
3:35 that's enough evidence for me.
Professor snape would be impressed by Hamilton's potions skills.
Professor Snape isn't real
Walter White as well
The dude literally start with basic 100 Alchemy skill when making a new character in Skyrim.
+
@@todayschef1734 people like you, crush hopes and dreams. Who cares if a fictional character isn't "real". Is anything actually "real"
The score of the first episode, and the series as a whole is fantastic.
Hamilton: "Any questions?"
The hippie in the audience: "How much per gram bro?"
Think a gram is like 100 doses..
@@nedaltrebor8553 My family doctor recommended ripping a gram out of a 30 inch bong as an appetizer
@@blindi6326 dare ya
Hippie and cash... ok🙄
@@BaelaLuv almost as if I was joking
Hamilton! My crown chakra is tingling. A little over a week ago RUclips took me on a binge of your previous adventures of experiencing this eyeblink of us seeing light bending in different ways and now I see your channel pop out of nowhere. The algorithm has been pleased and so am I. ❤️
God damn this dude as smart as hell I would love to have a friend that is good at chemistry like this dude.. but I honestly think he's on a whole another level.
joe rogan and hamilton morris podcast #3 were all waiting for it
They need to take it live on air lol
Hi Hamilton I hope you get to read this as I have been watching your videos across the internet since you began on Vice, and you've inspired me to do chemistry at college, currently studying Pharmaceutical and Medicinal Science in Ireland in my final 4th year! and without the passion and interest you have shown for chemistry I would have never done it. Lots of people make it out to be difficult yet I find it extremely interesting with that helping me learn much more, just wanted to say I'm so grateful even though you don't realize how much you've inspired me and other people. I would love study psychoactive compounds in the future thanks to all your work as well. Hope your good and maybe some day we will meet eachother! Thanks, Conal
I've watched this video like 29 times or more idk it's so many I just love the music and I get some kinda ASMR effect or something from hearing Hamilton talk about chemistry lol.
Some people are worried about these chemicals, yet still eat McDonald’s French fries 🍟
WTF?
Homie really compared DMT and McDonalds fries
say that
My man you ever trip ass on McDonald’s fries? LMAO
@@jjjj-x9g Yeah the fries will kill you and the DMT won't.
My brain while watching this: “Thank goodness I’m here.”
I have almost no scientific knowledge but I still find this fascinating.
Yet another reason to pay a visit to our friends on the other side of the Southern boarder.
🇲🇽👍
Mexico has always been our friends
We are all experiencing a time that I see being truly revolutionary in the space of human consciousness and the capability of the mind.
Lol?
Can you elaborate?
@@AAAAAAAAAAAAAAAAAAAAHH basically trying to fool yourself by running away from the truth instead of praising him.
You’re a living legend, Hamilton 🤜🤛
I just finished my second semester of organic chemistry at GVSU. I happened upon your show a few months in to my 1st semester last year and watched every episode, it's rewarding to be able to understand (for the most part) the many mechanisms discussed in the reactions in your show. Additionally, it's amazing how ultimately all the complex and enigmatic psychoactive effects from these compounds boil down to the infinitesimal transfer of electrons.
I think this show is giving many young people the spark, the inspiration they need to fuel their passion for learning science, and it is bringing light to the wondrous field of chemistry.
this is probably the most intense and overwhelming psychedelic i have ever tried. i have a massive amount of respect for this substance and it should be used with a shaman or someone who knows what they are doing.
I only know nn dmt and I strongly suggest some serious preparation before embarking. 5meo is said to be even stronger so even more precaution should be taken.
@@joeyg29jgjg There is no preparation you can do to prepare for a breakthrough DMT trip.
Lol Shaman... What horse shit...
I agree - after several 5-MEO experiences over the years, there are no words can remotely describe the experience . Only respect and awe for this amazing tryptamine.
@@foreignwarren7361 shamans are powerful
I'm just stoked because I actually understood his reaction analysis. O.chem 2 next semester here I come.
Thank you for helping to stop Toad abuse.
The real deal don’t hurt the toads they sing songs to them and the toad give the dmt to them naturally. No need to hurt the little fellas. Some people don’t understand this method they think it’s crazy lol they ain’t done it
@@alanspencer6417 yes this is nice, my sentence can have a better explanation applied concerning my word symantecs and your understanding.
@@alanspencer6417 just leave them toads alone... habitat destruction, animal slavery, etc... not a good look for getting a drug. and not to be pedantic, but for safety's sake, it is important to note the distinction between 5-meo-dmt and dmt. they are different drugs with different potencies, different fx, and different safety profiles.
hamilton, I want to thank you for inspiring me to return to chemistry as I’ve failed (numerous times) previously and had lost all motivation to study it.
thank you. your explanations are second to none and you are one of our generation’s greats.
If chemistry isn't your thing, there's lots of other areas to drugs that aren't covered in depth. There's neuroscience, metabolism, history, side effects, etc that are all still need documentation. :)
This is a chemist using his knowledge for an utterly worthwhile endeavor , the king of all medicines !!!
That shot of Hamilton as a cowboy and the miniature horse on S03E1 is amazing
I'm gonna tell my kids Hamilton is the real Heisenberg
😂😂😂
Please don't tell your kids a false narrative. He is nothing like the Heisenberg in Breaking Bad, which I assume you're reffering to, due to the position of "the real Heisenberg" being already occupied by an actual historic person that is know to have been a brilliant theoretical physicist.
If you compare Hamilton approach towards sharing knowledge to a rather ruthless druglord that acts mostly out of selfinterest, your perception of reality seems upside down to me..
@@uhmno587 it was a joke 🤦♂️
@@mrsinger5539 Ye, I get that this was his/her intention.. it's just that I had to think about it for less than the glance it took to me to read in order to shake my head in disappointment due to the lack of attachment to reality, which I tried to point out in my comment..
I don't wanna start a useless argument on Hamiltons Channel thou, so peace out an laugh about w/e you like, just don't cry because someone states your humor is off/trash.. :P
@@uhmno587 It's totally cool dude, have a good day
Reductive Amination: the clandestine chemist's favorite reaction.
It would be pretty neat to see the synthesis of 5-MeO-tryptamine from melatonin by hydrolysis, since said precursor is extremely expensive from chemical suppliers and requires the typical business license.
you can deacetylate it with naoh solution , heat to 105c in isobutanol for a few hours reduce the solvent down 50% , add 10% acetone and freeze it, youll get a bunch of good crystals , you can repeat it to scavenge the rest of the mexamine from solution on a second crystallization.
I’m for sure on a list somewhere rn
Banning chemicals its like banning dirt.
It's a ban on science based on fear.
It cures tobacco, alcohol and pill addiction just imagine how much money they would lose not destroying people’s lives with horrific addiction.
What does that have to do with dirt
@@Jake-vc1ry DMT cures addiction?
Yeah, bullshit buddy. Lmao.
@@DarthObscurity legalisation is proven to cure addiction. It's much easier to get help as an addict when you don't have to worry about being arrested
what about mustard gas?
Hey for educational purposes can you show us how to do it with soda bottles now?
"Ok, time for questions"
"Yes Joe Rogan, sitting in the front row, you have a question?"
Ah yes “Mexico”. The favorite among those who trip balls and street race ;)
I was involved with a vivacious group of people in the early 2000s that ran a true clandestine LSD lab I was dating a woman who's brother was a organic chemist at the University of Washington at the time we all lived in the "U" district and it was the most compelling time of my life. Long story short I agreed to be the fall guy when the feds were tipped off they ransacked the house found only a few legal precursor chems a 40 bag of weed. What they didn't even realize is that on the wall there was a 48x30 self portrait of van gogh made of pure blotter it was mostly inert due to light, oxygen exposure but goddamn what a wild ride I wish there were time machines! Happiness to everyone and peace!
Please reach out to me via email or instagram DM, I'd love to hear more about this and speak with the chemist if possible.
Time for questions-
Hippy in the back “where can I score some of these crystals you speak of”
He just told you how to get them step by step. I'd hate to be in his shoes since that's probably 90% of the questions he gets.
I've done this drug once, I literally stopped doing all drugs because of this shit...
Same DMT/related compounds are life savers. I hope this can become more available to those who need it soon. Was not easy to obtain here in Canada (I don't trust street sources.)
@@ME-ol9gk Id wager you could quite easily obtain it over the darknet, but this is obviously very illegal. However, it's usually such a small amount of substance it would be virtually almost impossible to detect amongst the thousands of other packages. Mine came packed in between a deck of playing cards.
Maybe you could consider trying mushrooms. I've no clue what the UK is like but they must be easier to obtain than DMT there.
@@ME-ol9gk I believe there are comprehensive resources on Reddit available to guide you. It's relatively safe to use the darknet when you follow directions carefully. I personally had spent thousands in the past with out issue.
same...over 20 years ago. Infinity
That's what I need. A real ego death of sorts. Time to strip down my shitty persona into core values to better myself.
The vibe u put out in your videos has gotten me outta so many bad trips. Keep being u
how do you prevent from going into a bad trip and why so many?
The best trip is the one where you dont have to hurt nature to get it and you still get the benefits
...and the one where you don't gamble losing everything in your life that you consider 'you' - good and bad.
@@commentatron what do you mean by that
@@chigbungus5257 Psychedelics like psilocybin, DMT, LSD etc. tend to affect your sense of self; your ego, the 'voice in your head.' Altering or obliterating that voice, even temporarily, can be risky. Depending on your starting point (and few really are so self-aware that they know themselves that deeply), you cannot be sure if the change will be one you want or can live with easily. Those that find it positive and magical sing it's praises, but less often heard are those that do not come back, and instead trigger a latent psychosis or other negative effect.
@@commentatron less heard about?? The fuck you on about? Prior to 2020 80% of what you heard about this substances was about the risk of triggering schizophrenia or pther mental disorders.. If you dont know that this shit comes with a risk its tour fault the information is out there.
@@Drogado68 Easy, my friend. No one's putting a psychedelic gun to your head.
I believe Every human being over 19 should try DMT at least once in their life time.
I used to feel strongly that most people under 19 should try LSD once, but then I turned 19 and that whole belief got turned on it's head.
Love you, Hamilton. Something about your personality is magnetic, and I just cant stop consuming your content!
"You're a damn artist!" -Jesse Pinkman
No no... it’s just basic chemistry.
@@godofdogs6198 yeah science!!
@@godofdogs6198 yeah science!!
Nice video but the mecanism he gives is kinda wrong, he's suggesting a cationic protonated alcohol leaving group during his reductive amination. You're never gonna form that in the presense of sodium borohydride (H-). Sorry, annoying O-chem PhD here :D
Hamilton's the Carl Sagan of inner space
Hamilton, the work that you are doing is changing the way people are viewing these gifts in our universe. Thank you for your gift 🎁. Much love
this man is an artist
I synthesized Hamilton Morris.
That guys seems hella chill.
You must have put a lot of love into this :)
1:59 it’s comforting to see Hamilton eat fresh fruit lol
I watched this a few years ago and it made no sense to me but I went to university to study chemistry and now it kinda makes sense! Except for the borohydride part, I haven't seen that before.
would love to volunteer as a lab assistant the whole procedure looks like so much fun
You're amazing. Keep doing your thing. For some reason when I saw the cuts to you eating a banana after talking about the synthesis, I thought about how much perspective matters. You're doing amazing things with chemistry, and then you cut to eating a simple banana. When I personally thought about it, I thought that both scenes are incredible in their own right. Obviously you synthesizing 5-meo-dmt, but also just how amazing it is that we're here and have bananas to eat. Depending on your perspective at the moment, both could seem uninteresting and dull. But another perspective could be that both are equally amazing. Im rambling, if you read this far have a good night. P.s. if you've got a dog, give them some love now!
Tf
I had this set on 0.5 speed because I was watching balisong tricks before, but now I think it is appropriate for this content.
I see what you did with that “high 5”.
High with 5-MeO-DMT
Hey Hamilton, I have been watching your experiments for a while now and I can say I am very impressed! I was wondering if you are willing to continue your research on the synthesis of tryptamine derivatives. The 5-MeO-tryptamine as a starting material is not accessible to a lot of chemists and industries around the world. How about the complete synthesis of DMT or other useful tryptamines from an indole or tryptophan as a starting material? The literature is very old and with a lot of mistakes.
Kind regards,
I Love your work!
5-meo-tryptamine can be made from melatonin. Easily accessible supplement
Bro, save the frogs. I didn't know you had a youtube channel, watched all your pharmacopeia episodes.
Instantly liked, favourited subscribed and bell notified all.
Hell yeah Hamilton.
I just love chemistry, that's why I'm here 😂
save the toads notice me hamilton pls it would make my year
Subscribe to his Patreon! He's usually pretty good at replying if you have a good question :)
"notice me hamilton"
Is he just a bad ass or what?! Bear would be proud of this man.
Ahhh yessss my organic chemistry is finally paying off!’n
XD
Hamilton is so humble he doesnt care if your torrent his show, he just wants the info to be out there and for people to be safe
All you have to do is focus on the ringing in your ears and nothing else until stops and... Awakening!
Breaking God. New series with the incredible Hamilton Morris, nominated for Nobel's Peace Price for mass spreading 5-MeO-DMT, bringing world peace
this man just saved the frogs
coming from a vegan he is helping save the exploitation of an animal with a low population and i thank him so much for it
They are actually losing population because they are often roadkill, not because they are milked.
Yeah but they are totally all turning gay
@@amirrhodesve791 how do you know somebody drives a tesla ?
Don't worry they'll tell you.
How do you know if somebody is vegan?
:)
@@francescocipriano407 i like to tell people im a vegan because animal activism is veganism :)
For those who want to do further research on this reaction, this is the Eschweiler-Clarke reaction, which is used for the selective n-methylation of primary and secondary amines. But the reaction traditionally uses highly concentrated formic acid instead of sodium borohydride.
I've wanted to try DMT for 30 years and have never had the chance.