Can't thank you enough for shedding the light on biologics, i have been suffering from RA and taking Methoteraxate injections weekly. the Nausea it gives me is unbearable, although my doctors have been adjusting the dose and also are recommending to consider the Biologics from a long time, this video will help me to decide the best according to my disease and affordability. God Bless You Sir !
Hi Dr Bose! I appreciate your efforts for spreading awareness among the patients. I am biopharma professional working for last almost 9 years in this domain as a scientist. Pls feel free to approach if you need any info about biologics developments
i have 20 nail Psoritic nail dystrophy and moderate scalp psoriasis without skin involved till now I'm taking vit d3 10k 𝙞𝙪 𝙙𝙖𝙞𝙡𝙮 and cod liver oil and multivitamin. Following right diet which r fruits and vegetables nut and seeds and avoid dairy nightshade and every processed foods After taking vit d I got some relief in my scalp flaking but nothing is working for my nails which leads to me toward depression. What I do Actually in my journey it started from one nails affected after that my scalp. Now I come off my all 20 nails. And now finger joint pain are developing its hurt .. And topically I have Applied everything on my nails whatever doctor Recommended Now I'm getting pain in my knees and right hand thumb pain and become flexible like not able to work What I do mam ? it's becoming serious day by day Should I take strong medicine Chemotherapic and biologics Please give some hope 🙏 I'm 23 years old
@@therheumatologistthejoints8861 Sir i am going to take biologics(Adalimumab 40mg) from next month. But i am confused with the brand that what should i use between Cipla (Plamumab inj) and Torrent Pharma( Adfrar inj)? Please suggest me. Cipla's inj is cheaper than Torrent Pharma. [ 1 year ago i took 6 Adfrar biologics inj(s) in 15 days gap upto 3months, and now (after 1 year gap) i am restarting biologics, but want to change the brand for cost... is it safe to change the brand from Torrent Pharma to Cipla? Is there anything to worry about my health after changing the biologics' brand? ]
Sir, I am Debashis Pan from Krishnagar,Nadia.I am suffering from psoriatic spondolyto arthritis. I had taken 7dosages of Adalipca one and half year ago. Now the same problem is back and I'm going through tremendous pain right now. Can you suggest any medicine to reduce my pain for immediate relief .
I have taken appointment in Balaji Medical , Kalyani in the month of November,2020. But for the time period, please suggest some medicine to relieve my extreme pain.
Thanks sir, My wife is 30 year old and she is suffering from RA which was very painful,our Dr. Suggested intacept 50 mg injection so I have so many doubt but by this video all are clear thanks one again for this informative video
Thanks for explaining those complex topics in a simple and lucid language. I am now 34 and a sports person from Bankura district. I diagnosed HLA 27 positive while feeling severe pain in shoulder, neck and the waist in last 2 months. I been prescribed 6 admira 40 mg injection in 2 weeks interval for 3 months by a rehumatologyist from appollo chennai. Can I come back in the field or live a normal life after taking all those medicines? Thank you sir 🙏
We actually follow international guidelines and none of the guidelines have recommended to stop any form of Biologics or stop from initiating any form of Biologics. However, in case a person who is on Biologics suffers from COVID, then it's indeed prudent to stop the Biologics immediately.
Sir am.from ghaziabad near delhi i am suffering from ankylosing spondilytis since last five year now am 20 year old my spine is paining continuously day by day nd now i am not able to bend down properly .my quality of life is worst now. i want to meet uh sir. Would u give online consultation? Sir how much biologics cost in one year of treatment?
Video consultation detail Fees : ₹1200/- How to pay? 1. Paytm/googlepay to 9830029963 2. UPI 9830029963@upi 3. NEFT detail Name: Tanoy Bose Bank: Oriental Bank of Commerce Branch: Garia Savings AC: 12412191003633 IFSC: ORBC0101241 4. For international patients : please pay Rs. 1500/- by clicking the link below www.paypal.me/paybos Share the screenshot of payment via WhatsApp at 9831336275 and the time and date for VC will be shared accordingly
Sir because of you thousands of people can live a normal life and walk around freely . I pray to God that you are always Happy and healthy . Thank you so much sir .🙏🏻🙏🏻
Thank you very much sir. You are the first person who explain biologics very clearly in hindi. I am a 32 year male from mumbai who suffering from AS since 18 at age. Trying so many medicine like indomathacin but it gives only 8 to 10 hour relief. Now thinking about biologics. But afraid of its cost and side effects. Please help as with your guidance . Thank you.
Hi I have already attempted to summarise the basic information on Biologics. Cost is a factor that hardly can be negotiated, but nowadays Biologics therapy cost has come down around 15K/month if not less.
Thank you Sir, my friend having the psoriasis, planning for Secukinumab injection, she is not able to plan baby due to this disease. My question is there any chance for her to plan baby after this injection period. I heard that in this duration pregnant lady can't take this injection. Sir could you please help Or suggest here?
Great speech, it's really great. I am AS patient, now I am living in Indore. I am touching with the doctor Akshat panday, he is recommended going to biological. AMAR SOB VHOI KATEYA DILEN SIR
Sir yesterday 2022 mere rheumatologist n tofacitinib 5 mg ko allow Kiya h us basis jo mene AIIMS m 2019 m tb , hiv test karaye the and negative the but mere ghar m sister ko bhi spine tb hua tha 2020 to kya mujhe dobara un sabhi test karane chaiye. Kya pta tb mujhe bhi ho bcz unhone 2019 k report dekhar tofacitinib allow ki h
Main 14 years se RA se suffer kar rahi hoon medicine bahut li hain mager koi fayda nahi hua sir kya main biologics le sakti hoon lekin price bahut high hain . Sir bahut achche se samjha rahe ho. bahut achcha lagta hain aapka clinic kaha hain sir ish disease ke wajah se mere dono ghutne khrab ho gaya hain sir kya main tkr karwaoo.
Apki samsya sunkar bura kaga. 80-85% log bina biologics par thik rehte hai. Rheumatoid ke wajah se ghutna barbad hota hai magar, wazan ke wajah se zyada barbad hota hai. Mera clinic sab Kolkata mein hai. Aap chaho to 9831336275 par whatsapp kar sakte ho.
Hello sir mujhe ankylosing spondylitis in advance stage, d10 d11 me bahut pain hai na sahi dang se let sakta, hu or kabhi kabhi to uth bhi nahi sakta na kahi aa sakta na kahi ja sakta life pain full or stress full ho gyi hai idher amritsar me koi rheumotolgist bhi nahi hai Kya main biologics se thik ho sakta hu Mera esr normal ata hai Mujhe punjab me biologics kaha se milega or mujhe kon sa biologics thik rahega kripa reply kare.
sir, lots of changes in 5 days. all the pain gone. next dose after 15 days. are the doses life long or can be stopped after maintaining through exercise? pls reply
Exactly powerful bolna mushkil hai. Agar Adfrar kaam nahi kar raha hai , iska matlab hai Adalimumab kaam nahi kar raha hai. Aap chaho to apke Rheumatologist se baat karke Infliximab nahi to Etanercept try kar saktey hai
Is it possible to have AS without raised inflammatory markers ESR CRP , hlab27 neg ,MRI in Feb 2022 normal , fibromyalgia can cause so pain one can feel difficulty in sitting?
Riruximab use full in ITP degese ,platlats count issue see some time is less than 8k but no empecty in my boday only when we check cbc than I will feel for the same I m ITP present now our dr advice 800mg weekly for 4week what tid the side effects for that
Hello Sir, this is very informative video. You have helped so many sufferers and earned lots of blessing ... without any selfish motive or any hidden information or agenda, you have revealed the facts... so it shows that you consider humanity above profession... Thank you so much... 🙏🙏
Hats off to you Sir for your valuable and easily comprehensible information about biologics....Many chronic patients are helpless but Sir you are their light of hope and inspiration to live.... Sir, to be frank, I have no words to thank you Sir, You are doing a GREAT job......♥️♥️♥️♥️♥️♥️♥️
Adfrar injection kitna din lena parega sir....mera opration huya hay 2 hip joint...and doctor nay bola hay mera ancological spondylosis hay..6 injection lenay kay liye bola hay...6 injection complite honay ki bad ...kiya or injection lena parega....sir...
I took one dose of inj humira last week. After that I have severe sacroiliitis and body and joint pain increased especially in sacroiliac joint pain. Due to sacroiliac joint pain I couldn't sit ,stand and walking also. Tonsillitis also started . Is it normal or not? My Dr said to me 3 month only want to take this injection. But it is life long or not?
🙏Namaskar sir. Mai as (hla b27 positive) patient hu. Mai biologics (MABVINRA- ADALIMUMAB) 15day pe 1 injection 40mg aur saath me saaz ds 1gm 2 time regular 6 month se le raha hu. Par pain abhi bhi bahut rehta hai kya karu. Please bataye.
Agar Mabvinra 40mg kaam nahi কর raha hai to niyam hai ki Biologic injcetion change kiya jata hai. Jaise, aap etanercept, Infliximab ya secukinumab le saktey hai.
Biologics sabse bariya kaam karta hai jab koi damage (Ankylosis) na hua ho. Aap ka 8 years ka bimari ke baad kis status pe hai yeh janna zaruri hai. Agar haddiya jur gai hai, to woh chhutega nahi..lekin nayi damage ruk sakti hai.
Tricky wuestion. Reseacrh and books dont suggest that Tofa works in Ank Spons. However, we have got mixed results when we have used in patients with peripheral Ank Spons. There is no harm in trying for at least 3 months and see the results.
Thanks a ton sir, sir i got a question, i have psoriatic arthritis since 2 years and i have got an injury on my ring finger. Will i cure the damaged finger through biologicals?
Very difficult to say. Interestingly Psoriasis follows a pattern called Koebner phenomenon . It means that any injured part of the skin might get affected by psoriasis in a patient who is already affected with psoriasis. So,. there are chances that the injury might get cured.
Thats a very complicated question. Yeh dawa actually genetic engineering se ek jiwit bastu ke andar banaya jaata hai, which is very complicated and difficult. Isiliye yeh dawa itna costly hota hai.
Good afternoon Dr. Sar meri wife arthritis hai r a factor bhi positive hai anticcp bhi high risk per hai right risht band ho gai hai aur doctor ne Salah di hai ki Tofacitinib 5 mg bd hai and hcqs 200 od ,celcal XT od kab tak leni hai kya rist khul sakti hai
Hello Sir, Suffering from Dermatomyositis age 34 ,planningf to take Rituximab, after taking Rituximab what are the precautions to be taken to avoid infection,Please suggest.
No specific precautions. Avoid live vaccinations and maintain standard health hygeine. Get vaccinated againts Flu, Pneumonia, Hep B, Zoster before the doses.
@@therheumatologistthejoints8861 Sir can the Dermatomyositis go away ,I am scared ,what is the next medicine after Rituximab,I have taken 2 doses of Rituximab
Sir mera coccydynia hai...r spondylitis vi hai.. Meri dr.advice diya injection lene ke liye ...mai 4 adalimumab mabvinra liye he ...sir mera tallbone mai pain kom nohi huya...mera sitting mai jada taklib hai... Kaise thik hoga sir...mai bohut poresan mai hu
Hi Coccygiodynia is not related to Ank Spons mostly. Even I had suffered from Coccygiodynia twice. It works by use of annular pillow for sitting all the time and sometimes alternate hot and cold compress. Avoid sitting on hard surfaces and abnormal psotures.
Rituximab for polymyositis is completely a rheumatologist’s decision. RTX is practically free from any serious side effects. However, episodes of throat infection, sunisitis, chest infection, herpes have been experienced which are not dangerous and can be managed on an outdoor basis.
Of course. Biologics like, Etanerceptg (~Rs.3500 for 50mg), Adlaimumab (~Rs.6000-7000 for 40mg), Infliximab (~Rs.12800 for 100mg) and Secukinumab (~Rs.15600 for 150mg) works well.
sir i m hla b27 positive and detected as ankolysing spondylitis and my treatment is going on by rheumatologist doctor and medicine given to me is etoricoxib 120 with r cenix 600 as i m detect montux test for tb is positive.sir one question here my back is pain and stiffs very severerly than other joints .i cant understand is this pain and stffness is from my back rib bone joints or from the back muscles.is this pain is fibromyalgia or due to ankolysing spondylitis.the stiffness is relief when i use a hot waterbag.but during streching exercises i feel this pain and stiffness very worse.so sir pls suggest me why this happened and second question why sir tv test is done ???? is my doctor is thinking for a biologic injection's for next.pls sir suggest me.
Answering the second question is easier: Yes, you rheumatologist is thinking of Biological injections for your Ankylosing Spondylitis. Regarding your first Question: Ankylosing spondylitis is basically an inflammatory disease rather than an autoimmune disease. We dont have a blood marker for Ank Spons (note: HLA B27 is a genetic marker and not a diagnostic marker as it might be positive in other diseases too). So for all practical purpose the generalised back pain, muscle pain, buttock pain and bodyache you are sufffering is due to Ank Spons. If you check your ESR and CRP, you might find it high. However, if the ESr and CRP are remarkably normal and the pains are disproportionate, then we might need to think of diseases like FM. However, FM has other symptoms as its accomplice eg Fatigue, Lethargy, Low mood, Poor concentration, headache, low abdominal pain, non descript scattered pain and tender points on body and most importantly Unrefreshed or nonrestorative sleep. Interestingly there is NO pathological similarity between AS and FM and they are two absolutely different entity.
Difficult Question. Agar posture mein change recent onset hai, jaisey maan lijiye last 3 mahiney se posture change ho raha hai, tab Biologics can correct that. Lekin agar maan lijiye 2-3 saal se tera ho chuka/chukey hai, to sidha hona mushkil hai
I am suffering with spondiloarthopathy from last 12 years . It's very painful, I can't buy this injection ,I have Swasthya sathi card .can I get this injection ? Please reply
Namaste Sir ji. Am taking biological therapy Adlumab 40 mg. Sir I want to know can I do Yoga PRANAYAM KAPALBHATI , ANULOM BILOM AND CAN I TAKE AYURVEDIC MEDICINE ALSO WITH THIS BIOLOGIC INJECTION
Abhay Singh Of course you can do all forms of yoga. Since Ayurvedic medicines are approved in India under ministry of. AYUSH, I certainly cannot ask you to avoid them and further I have no idea what Ayurvedic medications you have been prescribed, what are the benefits and side effects. You should consult your local physician in this regard. Broadly we ask patients not to stop modern allopathy medications even if u take any alternative medications.
Hello sir, i m suffering from AS (ankylosing Spondolyties) , i was took infliximab very early stage but it's not work then my dr suggest Adalimumab it's work and I have been taken till date but my body resistance for adalimumab... Can you pl suggest any other next biological? or is nothing more than this?
Sir amar ankylosing spondylitis hoyese, amar hip joint fixt hoye gese, ama k Dr. Injection simponi golimumab dete bolese, ai injection er kono side effects ase ki na sir
I am suffering from RA for the last one year and on Eternacept for the last 10 months. I am feeling better and having pain in my right hand finger joints. Morning stiffness is in both hands. Please advise how I can reduce the dose or can add DMARDs with injection. Please advise.
Methotrexate ( maximum dose 25mg/week) should be one of the medicines you must be taking along with either of HCQ, Sulfasalzine and Leflunomide. If these are there and you still need biologics, then you can consider adding Tofacitinib and switching off Biologics.
Sachin Karape sorry for responding in English. My keyboard prompts lots of typing error. No,etanercept is essentially a safe drug without any adverse effects. It might cause some local pain in injection site and sometimes a low flu like illness, but vomitting and dizziness is unheard of
Sir, sovo sandya, Mein Bangladesh se hon. Mein SPA, uveitis HLA-B-27 positive patient. Mera ek sawal- Bangladesh ka ek rheumatologist moje adalimumb Lene kelie kahahein. Lekin mein chosme padgiehain k Mein kia biologics leneka pahle COVID-19 vaccine leisaktahon? Our ek bat Hein Mein Bangladesh se kounsa company ka adalimumb injection loun
Bose podobir lokera jotoi Hindi te kotha boluk na keno, adopey banagliee hoy :P COVID vaccine nitei paren. Ideally duto vaccine niye Biologics shuru korle bhalo. Bangladesh er Adalimumab shombondhye ek binduo idea nei amar.
@@therheumatologistthejoints8861 নমস্কার মহাশয়। যদি বাংলাদেশের adalimumb বিষয়ে আপনার আইডিয়া না থাকে তা হলে আমি সাধারণ একজন রোগীর সে ক্ষেত্রে করণীয় কি হতে পারে? তাছাড়া এই ইনজেকশনটির পার্শ্বপ্রতিক্রিয়া বিষয় জানতে চাইছি যেহেতু নিয়মিত বা অনিয়মিতভাবে নিতেই যখন হবে। অসংখ্য ধন্যবাদ।
sir , my father suffering crohns disease and hla b27+ , left pair k punjo me kafi dard ho rha h...rhemmatogy dr give suggest for bilogics ..but i ask its safe for patient yes or no..
Prashant Kusumbe Hi, you can reach to WhatsApp no9831336275 for online consultation. You will be provided all the detail for how to do video consultation.
Dr Sir, Greetings! I am suffering from recurring anterior Uveitis. Pelvic region MRI and X-Rays of whole spine did not indicate ankylosing spondylitis. I am taking Folitrax 15 mg weekly for last two months but it has not reduced eye inflammation. Eye specialist suggested treatment with immuno suppressants or biologics. Pl advise which biologics will be more appropriate for me. Thanks and regards.
Excellent question. There are patient with pure recurrent anetrior uveitis with B27 Positive with no other rheumatological disease. Please consult a rheumatologist and I think you might respond very well to Adalimumab injections. Quite a lot of my patients are doing well with a success rate of around 80-85% (to be honest).
dear sir salam.Sir ye jo infiximabe dosage jo ha agr ye female patient ko lagady to prignance step pr koe asar pare ge matlab dosae lagane ke bad bache paida kar sakty ha
Sir mai hla b 27 positive hu +jai arthritis he +avn ho gaya he left hip joint ko partially fused he mujhe adalimumab suggest kiye he one in 15days kya me le Sakta hu it will stop hip arthritis? ? Pls reply sir
I am afraid, I am sorry. Even if u take the costliest of drugs', Ank Spons wont be eradicated, But with drugs like Adalimumab, you can stay free from the disease as long as you wish
I am suffering from ankolysing spondylitis from 7 years.My body is fully fused. No flexibility. I am just a straight bamboo . Will this injection help me???? If yes then please tell me the name
Frankly speaking, he injections wont make a huge difference in a fused spine. However, it will prevent further fusion and retard or reverse any freshly formed fusion and might deliver some flexibility and significant pain reduction.
Sir I am suffering from Hidradenitis suppurativa from last 4 yeras...I have taken all the antibiotics but now condition is that I am not able to do my normal work.. Doctor is asking to take Adalumab (Humira) or surgery...which one is preferred sir... Please help..
Sir, i am frm bangladesh. I am a RA patient, taking adalimumab injection every month fr last 05 years & salfasalazine 2+0+2 every day fr 01 year along with adalimumab. I scared abt infection & experienceing mild breathing prob. Can i switch to jak inhibitor frm adalimumab or any other option. It would be helpful, if u reply.
Can't thank you enough for shedding the light on biologics, i have been suffering from RA and taking Methoteraxate injections weekly. the Nausea it gives me is unbearable, although my doctors have been adjusting the dose and also are recommending to consider the Biologics from a long time, this video will help me to decide the best according to my disease and affordability. God Bless You Sir !
Thanks for the kind words of appreciation
Did you take biologics?
Since I am a RA patiant for last 7 years and your information is useful inough, thanks
Glad it was helpful!
Very well explained... In detail and simple language for layman.
Many thanks.. Kindly share and subscribe
Mai As se safar kr rhi hu aapki video dekhakar sari confusion dur ho gai Sare ke sare point ko aane bahut achhe se explain kiya🙏
Thanks a lot
Hi Dr Bose! I appreciate your efforts for spreading awareness among the patients. I am biopharma professional working for last almost 9 years in this domain as a scientist. Pls feel free to approach if you need any info about biologics developments
i have 20 nail Psoritic nail dystrophy and moderate scalp psoriasis without skin involved till now
I'm taking vit d3 10k 𝙞𝙪 𝙙𝙖𝙞𝙡𝙮 and cod liver oil and multivitamin. Following right diet which r fruits and vegetables nut and seeds and avoid dairy nightshade and every processed foods
After taking vit d I got some relief in my scalp flaking but nothing is working for my nails which leads to me toward depression. What I do
Actually in my journey it started from one nails affected after that my scalp. Now I come off my all 20 nails. And now finger joint pain are developing its hurt ..
And topically I have Applied everything on my nails whatever doctor Recommended
Now I'm getting pain in my knees and right hand thumb pain and become flexible like not able to work
What I do mam ?
it's becoming serious day by day
Should I take strong medicine
Chemotherapic and biologics
Please give some hope 🙏
I'm 23 years old
Definitely. Thanks for the proposal
Thanks for the complete information about the biologics treatment.
Thank you; i am your big fan...
Tanmay Saha Its really an honour to hear that.
@@therheumatologistthejoints8861
Sir i am going to take biologics(Adalimumab 40mg) from next month.
But i am confused with the brand that what should i use between Cipla (Plamumab inj) and Torrent Pharma( Adfrar inj)?
Please suggest me.
Cipla's inj is cheaper than Torrent Pharma.
[ 1 year ago i took 6 Adfrar biologics inj(s) in 15 days gap upto 3months, and now (after 1 year gap) i am restarting biologics, but want to change the brand for cost...
is it safe to change the brand from Torrent Pharma to Cipla?
Is there anything to worry about my health after changing the biologics' brand? ]
Very informative video
Thank you so much sir
Sir, I am Debashis Pan from Krishnagar,Nadia.I am suffering from psoriatic spondolyto arthritis. I had taken 7dosages of Adalipca one and half year ago. Now the same problem is back and I'm going through tremendous pain right now. Can you suggest any medicine to reduce my pain for immediate relief .
I have taken appointment in Balaji Medical , Kalyani in the month of November,2020. But for the time period, please suggest some medicine to relieve my extreme pain.
@@debashispan8477how are you now
Thanks sir, My wife is 30 year old and she is suffering from RA which was very painful,our Dr. Suggested intacept 50 mg injection so I have so many doubt but by this video all are clear thanks one again for this informative video
Happy to help
Thanks for explaining those complex topics in a simple and lucid language. I am now 34 and a sports person from Bankura district. I diagnosed HLA 27 positive while feeling severe pain in shoulder, neck and the waist in last 2 months. I been prescribed 6 admira 40 mg injection in 2 weeks interval for 3 months by a rehumatologyist from appollo chennai. Can I come back in the field or live a normal life after taking all those medicines? Thank you sir 🙏
Hi bappajit, how are you now?
Same my condition
Bhai how are you now?
@@kukurocks1 several restrictions imposed. But avi thik hu. Give up physical activity only walking 2 km daily.taking medicines timely. Thank you
@@bappajitchatterjee5112 still taking biologics
Very informative. Suffering from AS for last 40 yrs.
Respected sir. Does these biological agents are safe In the setting of corona virus? Pls narrate ur recomendation. Regards drmubashir 🇵🇰
We actually follow international guidelines and none of the guidelines have recommended to stop any form of Biologics or stop from initiating any form of Biologics. However, in case a person who is on Biologics suffers from COVID, then it's indeed prudent to stop the Biologics immediately.
How long want to take this injection? In between can stop the medication?
Sir am.from ghaziabad near delhi i am suffering from ankylosing spondilytis since last five year now am 20 year old my spine is paining continuously day by day nd now i am not able to bend down properly .my quality of life is worst now. i want to meet uh sir. Would u give online consultation? Sir how much biologics cost in one year of treatment?
Video consultation detail
Fees : ₹1200/-
How to pay?
1. Paytm/googlepay to 9830029963
2. UPI 9830029963@upi
3. NEFT detail
Name: Tanoy Bose
Bank: Oriental Bank of Commerce
Branch: Garia
Savings AC: 12412191003633
IFSC: ORBC0101241
4. For international patients : please pay Rs. 1500/- by clicking the link below
www.paypal.me/paybos
Share the screenshot of payment via WhatsApp at 9831336275 and the time and date for VC will be shared accordingly
So beautiful you teach us thanku so much sir
So nice of you
Sir because of you thousands of people can live a normal life and walk around freely . I pray to God that you are always Happy and healthy . Thank you so much sir .🙏🏻🙏🏻
thanks and please like, share and subscribe
Dr Sb well come sir
I'm HLA B27 positive
I was under treatment of biologics from jan 2018 to Dec 2019
Are you still talking any medicine?
Dr sahab U given mind blowing Information about biosimilar and Auto immune disease like RA plz provide Ur Mob no
Thanks & Regards
Rajendra
Jaipur
Itna acha expln kiya ap ny thnkx
Very nice lecture sir , thanks
Most welcome
Govt hospital mai bilogical milte hai
Thanks sir ,for information
Thank you very much sir.
You are the first person who explain biologics very clearly in hindi.
I am a 32 year male from mumbai who suffering from AS since 18 at age.
Trying so many medicine like indomathacin but it gives only 8 to 10 hour relief.
Now thinking about biologics. But afraid of its cost and side effects.
Please help as with your guidance .
Thank you.
Hi
I have already attempted to summarise the basic information on Biologics. Cost is a factor that hardly can be negotiated, but nowadays Biologics therapy cost has come down around 15K/month if not less.
Just find details of wholeseller, it is available on wholesale price.
Thank you Sir, my friend having the psoriasis, planning for Secukinumab injection, she is not able to plan baby due to this disease. My question is there any chance for her to plan baby after this injection period. I heard that in this duration pregnant lady can't take this injection.
Sir could you please help Or suggest here?
Yes during pregnancy these medications should be avoided
Inj intacept 50mg slip disc or sitica mein liya jata hai kya
sir please "tofacitinib for ankylosing spondylitis" pr video banayiye.
Sure… TOFACITINIB is not approved for Ank Spons.
Thanks a lot sir, for detailed information..
So nice of you. Kindly subscribe and share
Aryuvedic treatment for ank sopndy pleas bataiye
Ayurvidec treatment ke barey mein mujhe koi idea nahgi hai.
Great speech, it's really great. I am AS patient, now I am living in Indore. I am touching with the doctor Akshat panday, he is recommended going to biological.
AMAR SOB VHOI KATEYA DILEN SIR
Thank you
Rituximab cost kitne ha
He is good doctor or you can show to Dr Sourabh Malviya ji too. He is best there.
Biologics is good and helpful.
@@ashishchowdhary1334Depends on city
🙏 बहुत ही अच्छी जानकारी आसान भाषा में मुझे भी हर छह माह मेंrituximab इंजेक्शन लगते हैं
Swasth rahiye
Hi please given your contact number
Sir yesterday 2022 mere rheumatologist n tofacitinib 5 mg ko allow Kiya h us basis jo mene AIIMS m 2019 m tb , hiv test karaye the and negative the but mere ghar m sister ko bhi spine tb hua tha 2020 to kya mujhe dobara un sabhi test karane chaiye. Kya pta tb mujhe bhi ho bcz unhone 2019 k report dekhar tofacitinib allow ki h
Main 14 years se RA se suffer kar rahi hoon medicine bahut li hain mager koi fayda nahi hua sir kya main biologics le sakti hoon lekin price bahut high hain . Sir bahut achche se samjha rahe ho. bahut achcha lagta hain aapka clinic kaha hain sir ish disease ke wajah se mere dono ghutne khrab ho gaya hain sir kya main tkr karwaoo.
Apki samsya sunkar bura kaga. 80-85% log bina biologics par thik rehte hai. Rheumatoid ke wajah se ghutna barbad hota hai magar, wazan ke wajah se zyada barbad hota hai. Mera clinic sab Kolkata mein hai. Aap chaho to 9831336275 par whatsapp kar sakte ho.
Thank u sir ❤
Tofacitinib..kya life long le sakte hai...iska koi side effects hai...??
Thanks for such a nice explanation sir is there any update in 2024
Sir reactive arthritis ke liye kon sa biologic treatment m injection better h
You can choose between Adalimumab, Etanercept, Infliximab,
Hello sir mujhe ankylosing spondylitis in advance stage, d10 d11 me bahut pain hai na sahi dang se let sakta, hu or kabhi kabhi to uth bhi nahi sakta na kahi aa sakta na kahi ja sakta life pain full or stress full ho gyi hai idher amritsar me koi rheumotolgist bhi nahi hai
Kya main biologics se thik ho sakta hu
Mera esr normal ata hai
Mujhe punjab me biologics kaha se milega or mujhe kon sa biologics thik rahega kripa reply kare.
Hello sir I am Adil Hussain from UAE sir my problem Hidradenitis suppurative which injection need and which blood test need
That’s a dermatological disease. I appreciate your question but HS is not exactly my domain. I need to read and then get back to u
i m going to start from tomorrow in kathmandu. As patient. very informative
Great. Safe journey
sir, lots of changes in 5 days. all the pain gone. next dose after 15 days. are the doses life long or can be stopped after maintaining through exercise? pls reply
Sir ADFRAR 40 mg se better powerful koi injection hai ,ADFRAR 40 mg utni achhi kaam nehi deraha hai please tell me
Exactly powerful bolna mushkil hai. Agar Adfrar kaam nahi kar raha hai , iska matlab hai Adalimumab kaam nahi kar raha hai. Aap chaho to apke Rheumatologist se baat karke Infliximab nahi to Etanercept try kar saktey hai
Is it possible to have AS without raised inflammatory markers ESR CRP , hlab27 neg ,MRI in Feb 2022 normal , fibromyalgia can cause so pain one can feel difficulty in sitting?
Ank Spons can be possible without any positive findings but the MRI. The MRI has to show Sacroiliitis to prove tat its AS.
Riruximab use full in ITP degese ,platlats count issue see some time is less than 8k but no empecty in my boday only when we check cbc than I will feel for the same
I m ITP present now our dr advice 800mg weekly for 4week what tid the side effects for that
I hardly could understand your question. You can write in Hindi too if u wish
Hello Sir, this is very informative video. You have helped so many sufferers and earned lots of blessing ... without any selfish motive or any hidden information or agenda, you have revealed the facts... so it shows that you consider humanity above profession...
Thank you so much... 🙏🙏
Thank you so very much. Kindly spread the video.
I am hlb a27 positive.i have to operate disk de generative at l4 l5.now I am suffering neck stiffness since 02 years. Shall I recover?
Hats off to you Sir for your valuable and easily comprehensible information about biologics....Many chronic patients are helpless but Sir you are their light of hope and inspiration to live....
Sir, to be frank, I have no words to thank you Sir, You are doing a GREAT job......♥️♥️♥️♥️♥️♥️♥️
So many thanks. Kindly share and subscribe
Sir alopecia universalis me bhi use kar sakte hai
Yes. Lekin yeh dermatologist bata sakte hain behtar.
Adfrar injection kitna din lena parega sir....mera opration huya hay 2 hip joint...and doctor nay bola hay mera ancological spondylosis hay..6 injection lenay kay liye bola hay...6 injection complite honay ki bad ...kiya or injection lena parega....sir...
Ideally sara zindagi lena parta hai… but aap apney doctor se baat karke dose ko customise kar saktey hai
I took one dose of inj humira last week. After that I have severe sacroiliitis and body and joint pain increased especially in sacroiliac joint pain. Due to sacroiliac joint pain I couldn't sit ,stand and walking also. Tonsillitis also started . Is it normal or not? My Dr said to me 3 month only want to take this injection. But it is life long or not?
Sir kya tofe tablet lene se weight gain hota hai
Hello sir
Is Inj.remicade safe to take during 6 month of pregnancy
Excellent 👍👍
🙏Namaskar sir.
Mai as (hla b27 positive) patient hu.
Mai biologics (MABVINRA- ADALIMUMAB) 15day pe 1 injection 40mg aur saath me saaz ds 1gm 2 time regular 6 month se le raha hu.
Par pain abhi bhi bahut rehta hai kya karu.
Please bataye.
Agar Mabvinra 40mg kaam nahi কর raha hai to niyam hai ki Biologic injcetion change kiya jata hai. Jaise, aap etanercept, Infliximab ya secukinumab le saktey hai.
Sir RA arthirtih se skin allergy hota he sir long time skin allergy he darmographisam howa he 5/6 sal se so join pain bi hota he
Dermatographism is calssical skin allergy. It may not be related to rheumatoid arthritis and may be present in the person as a seperate disease.
Sir muze AS hai HLAB27+ 8 years se kya boilogics inj lekar meri jo jakhadan hai jaise ki neck ki o thik ho payegi or kitbe din tak asar rahega
Biologics sabse bariya kaam karta hai jab koi damage (Ankylosis) na hua ho. Aap ka 8 years ka bimari ke baad kis status pe hai yeh janna zaruri hai. Agar haddiya jur gai hai, to woh chhutega nahi..lekin nayi damage ruk sakti hai.
Do you have to be on biological injections through out life for chrohns disease
Ideally Biologics are for lifetime for all diseases.
abhi kaise ho app jaivaswani
Is Tofacitinib working for AS
Tricky wuestion. Reseacrh and books dont suggest that Tofa works in Ank Spons. However, we have got mixed results when we have used in patients with peripheral Ank Spons. There is no harm in trying for at least 3 months and see the results.
@@therheumatologistthejoints8861 Thank you Sir for your kind reply
Sir, You are so kind and so simple.... I will pray for your good health .....
Thank you so very much. Sorry for delayed acknowledgement
Doctor,How its work on sarcoidosis ?
Thanks a ton sir, sir i got a question, i have psoriatic arthritis since 2 years and i have got an injury on my ring finger. Will i cure the damaged finger through biologicals?
Very difficult to say. Interestingly Psoriasis follows a pattern called Koebner phenomenon . It means that any injured part of the skin might get affected by psoriasis in a patient who is already affected with psoriasis. So,. there are chances that the injury might get cured.
Biological kis products sa Banta ha or kaisa ready karta ha plz
Thats a very complicated question. Yeh dawa actually genetic engineering se ek jiwit bastu ke andar banaya jaata hai, which is very complicated and difficult. Isiliye yeh dawa itna costly hota hai.
What’s is your opinion for ozone injection therapy treatment for ankylosis spondylitis
Simply have no idea.
Good afternoon Dr.
Sar meri wife arthritis hai r a factor bhi positive hai anticcp bhi high risk per hai right risht band ho gai hai aur doctor ne Salah di hai ki Tofacitinib 5 mg bd hai and hcqs 200 od ,celcal XT od kab tak leni hai kya rist khul sakti hai
Rumotide arthritis
Yeh wrist agar last 3 month mein atak gaya hai to khul sakti hai with medicine and exercise. Magar bohut purana hai to nahi khulega
Thank you sir...if one have mild runny nose after the first shot of adalimumab should they take paracetamol like NAMCOLD etc..
Thats not worrysoem and not always can be attributed to Adalimumab.
Hello Sir, Suffering from Dermatomyositis age 34 ,planningf to take Rituximab, after taking Rituximab what are the precautions to be taken to avoid infection,Please suggest.
No specific precautions. Avoid live vaccinations and maintain standard health hygeine. Get vaccinated againts Flu, Pneumonia, Hep B, Zoster before the doses.
@@therheumatologistthejoints8861 Sir can the Dermatomyositis go away ,I am scared ,what is the next medicine after Rituximab,I have taken 2 doses of Rituximab
Dr.
Mera HLA b27 positive,
ANA positive,
MRI report Sacroiliitis,
ESR CRP normal,
Bich bich me aram but fr se pain shuru ho jata hai...
Kindly consult a rheumatologist for full explanation of your disease.
Sir mera coccydynia hai...r spondylitis vi hai..
Meri dr.advice diya injection lene ke liye ...mai 4 adalimumab mabvinra liye he ...sir mera tallbone mai pain kom nohi huya...mera sitting mai jada taklib hai...
Kaise thik hoga sir...mai bohut poresan mai hu
Hi
Coccygiodynia is not related to Ank Spons mostly. Even I had suffered from Coccygiodynia twice. It works by use of annular pillow for sitting all the time and sometimes alternate hot and cold compress. Avoid sitting on hard surfaces and abnormal psotures.
Sir me adalimumab injection 40 weekly le ha ho uska LABLE TEST. hota he kya please reply
Perhaps NO. Mainey abhi tak suna nahi aur kisiko kartey huye dekha bhi nahi regarding Adalimumab levels testing.
Can I take RITUXIMUB INJECTION for POLYMYOSITIS. What are the long and short term side affect.?
Rituximab for polymyositis is completely a rheumatologist’s decision. RTX is practically free from any serious side effects. However, episodes of throat infection, sunisitis, chest infection, herpes have been experienced which are not dangerous and can be managed on an outdoor basis.
Sir psoriasis me biologics life long chalta hai kya or ek injection ka cost kum sum kitna hota hai.
Of course. Biologics like, Etanerceptg (~Rs.3500 for 50mg), Adlaimumab (~Rs.6000-7000 for 40mg), Infliximab (~Rs.12800 for 100mg) and Secukinumab (~Rs.15600 for 150mg) works well.
@@therheumatologistthejoints8861 sir ye life long chalta hai kya or eske side effects kidney liver par Hota Hai kya sir.
Thank you sir bahut acha ap samjhaye h ... mujhe v bilogis doctor ne bola h
Thanks for the information sir
These biological are very costly
Govt must do something. Govt. Must provide it on affordable rate.
Life is valuable
You are right. Some biologics are available at Government Hospital, but you need to get in touch with a Govt Hospital Doctor for that.
Sir what about etanarel injection by reliance?? Is it trust worthy for RA?
Why not? Till date I do not have any evidence stating that one brand is better than the other.
sir i m hla b27 positive and detected as ankolysing spondylitis and my treatment is going on by rheumatologist doctor and medicine given to me is etoricoxib 120 with r cenix 600 as i m detect montux test for tb is positive.sir one question here my back is pain and stiffs very severerly than other joints .i cant understand is this pain and stffness is from my back rib bone joints or from the back muscles.is this pain is fibromyalgia or due to ankolysing spondylitis.the stiffness is relief when i use a hot waterbag.but during streching exercises i feel this pain and stiffness very worse.so sir pls suggest me why this happened and second question why sir tv test is done ???? is my doctor is thinking for a biologic injection's for next.pls sir suggest me.
Answering the second question is easier:
Yes, you rheumatologist is thinking of Biological injections for your Ankylosing Spondylitis.
Regarding your first Question:
Ankylosing spondylitis is basically an inflammatory disease rather than an autoimmune disease. We dont have a blood marker for Ank Spons (note: HLA B27 is a genetic marker and not a diagnostic marker as it might be positive in other diseases too). So for all practical purpose the generalised back pain, muscle pain, buttock pain and bodyache you are sufffering is due to Ank Spons. If you check your ESR and CRP, you might find it high. However, if the ESr and CRP are remarkably normal and the pains are disproportionate, then we might need to think of diseases like FM. However, FM has other symptoms as its accomplice eg Fatigue, Lethargy, Low mood, Poor concentration, headache, low abdominal pain, non descript scattered pain and tender points on body and most importantly Unrefreshed or nonrestorative sleep. Interestingly there is NO pathological similarity between AS and FM and they are two absolutely different entity.
Sir, you gave the information which will cost me like thousands of rupees and you just gave me those informations for free god bless you sir. ❤️❤️❤️
It's my pleasure
Kya Infliximab lene se body posture
Normal ho sakta hai. Please reply 🖕
Difficult Question. Agar posture mein change recent onset hai, jaisey maan lijiye last 3 mahiney se posture change ho raha hai, tab Biologics can correct that. Lekin agar maan lijiye 2-3 saal se tera ho chuka/chukey hai, to sidha hona mushkil hai
Thanks for reply sir 🙏
I am suffering with spondiloarthopathy from last 12 years . It's very painful, I can't buy this injection ,I have Swasthya sathi card .can I get this injection ? Please reply
Perhaps u can. But only after the COVID pandemic is over. U can visit any government hospital for this benefit
I am the patient of pemphigus vulgaris and also have ibs issue along with palpitations. Can I.take this INJECTION
IBS has got nothing to do with Biologics. If your dermatologist prescribes RTX , definitely u can go ahead.
hla as ke patient ke children my ye bemary hosakty hy mean patcient ko marriage karny chaheya ya nahi
Namaste Sir ji.
Am taking biological therapy Adlumab 40 mg. Sir I want to know can I do Yoga PRANAYAM KAPALBHATI , ANULOM BILOM AND CAN I TAKE AYURVEDIC MEDICINE ALSO WITH THIS BIOLOGIC INJECTION
Abhay Singh Of course you can do all forms of yoga. Since Ayurvedic medicines are approved in India under ministry of. AYUSH, I certainly cannot ask you to avoid them and further I have no idea what Ayurvedic medications you have been prescribed, what are the benefits and side effects. You should consult your local physician in this regard. Broadly we ask patients not to stop modern allopathy medications even if u take any alternative medications.
Hello sir, i m suffering from AS (ankylosing Spondolyties) , i was took infliximab very early stage but it's not work then my dr suggest Adalimumab it's work and I have been taken till date but my body resistance for adalimumab...
Can you pl suggest any other next biological? or is nothing more than this?
Of course , there is much more. You can try, Etanercept, Golimumab and Finally Secukinumab.
Sir amar ankylosing spondylitis hoyese, amar hip joint fixt hoye gese, ama k Dr. Injection simponi golimumab dete bolese, ai injection er kono side effects ase ki na sir
Biologics er side effect jerokom hoy, sherokom is sideeffect.. discuss kora achhe
I am suffering from RA for the last one year and on Eternacept for the last 10 months. I am feeling better and having pain in my right hand finger joints. Morning stiffness is in both hands. Please advise how I can reduce the dose or can add DMARDs with injection. Please advise.
Methotrexate ( maximum dose 25mg/week) should be one of the medicines you must be taking along with either of HCQ, Sulfasalzine and Leflunomide. If these are there and you still need biologics, then you can consider adding Tofacitinib and switching off Biologics.
Inanarcept se omtining Jaise ya chakaar ATA hai kya please bata dijiye
Sachin Karape sorry for responding in English. My keyboard prompts lots of typing error. No,etanercept is essentially a safe drug without any adverse effects. It might cause some local pain in injection site and sometimes a low flu like illness, but vomitting and dizziness is unheard of
@@therheumatologistthejoints8861 thanks
Sir, sovo sandya, Mein Bangladesh se hon. Mein SPA, uveitis HLA-B-27 positive patient. Mera ek sawal- Bangladesh ka ek rheumatologist moje adalimumb Lene kelie kahahein. Lekin mein chosme padgiehain k Mein kia biologics leneka pahle COVID-19 vaccine leisaktahon? Our ek bat Hein Mein Bangladesh se kounsa company ka adalimumb injection loun
Bose podobir lokera jotoi Hindi te kotha boluk na keno, adopey banagliee hoy :P
COVID vaccine nitei paren. Ideally duto vaccine niye Biologics shuru korle bhalo. Bangladesh er Adalimumab shombondhye ek binduo idea nei amar.
@@therheumatologistthejoints8861 নমস্কার মহাশয়। যদি বাংলাদেশের adalimumb বিষয়ে আপনার আইডিয়া না থাকে তা হলে আমি সাধারণ একজন রোগীর সে ক্ষেত্রে করণীয় কি হতে পারে?
তাছাড়া এই ইনজেকশনটির পার্শ্বপ্রতিক্রিয়া বিষয় জানতে চাইছি যেহেতু নিয়মিত বা অনিয়মিতভাবে নিতেই যখন হবে। অসংখ্য ধন্যবাদ।
জ্বি মহাশয়, যদি ঐ বিষয়ে জানাতেন।
sir , my father suffering crohns disease and hla b27+ , left pair k punjo me kafi dard ho rha h...rhemmatogy dr give suggest for bilogics ..but i ask its safe for patient yes or no..
Of course safe…. Less than 1% patients have any side effects of concern
Sir muze ulcerative colitis or AS hai... muze konta injection suru karna chahiye.. plz bataye sir... aapka whats no bataye sir plz
Prashant Kusumbe Hi, you can reach to WhatsApp no9831336275 for online consultation. You will be provided all the detail for how to do video consultation.
Dr Sir,
Greetings!
I am suffering from recurring anterior Uveitis. Pelvic region MRI and X-Rays of whole spine did not indicate ankylosing spondylitis.
I am taking Folitrax 15 mg weekly for last two months but it has not reduced eye inflammation. Eye specialist suggested treatment with immuno suppressants or biologics.
Pl advise which biologics will be more appropriate for me.
Thanks and regards.
Excellent question. There are patient with pure recurrent anetrior uveitis with B27 Positive with no other rheumatological disease. Please consult a rheumatologist and I think you might respond very well to Adalimumab injections. Quite a lot of my patients are doing well with a success rate of around 80-85% (to be honest).
@@therheumatologistthejoints8861 Thanks Doctor...!!
Sir, how can fusion of spine can be cured if it is fused by 90 % , is operation is the only solution ?
Sir scapho aur tofacitinib m mere liye kya sahi rahega.i m suffering with AS.and my monto is positive
Mantoux positive hai to apko 2mahine tak TB ka dawa khana parega + either Scapho or Tofa use kar sakte hai. Scapho is better than tofa
dear sir salam.Sir ye jo infiximabe dosage jo ha agr ye female patient ko lagady to prignance step pr koe asar pare ge matlab dosae lagane ke bad bache paida kar sakty ha
Thank you sir for your detailing.
I have psoriasis. Is biologics are effective for me?
Of course. Biologics like, Etanerceptg, Adlaimumab, Infliximab and Secukinumab works well.
Sir mai hla b 27 positive hu +jai arthritis he +avn ho gaya he left hip joint ko partially fused he mujhe adalimumab suggest kiye he one in 15days kya me le Sakta hu it will stop hip arthritis? ? Pls reply sir
Surely. Lekin apna AVN adalimumab se thik anhi hoga. Uske liye you have go for Hip replacement
Thank you sir
Sir can you tell me that i have taken adalimumab injection, AS completely cure from my body.
Pls reply
I am afraid, I am sorry. Even if u take the costliest of drugs', Ank Spons wont be eradicated, But with drugs like Adalimumab, you can stay free from the disease as long as you wish
apna experience short me share kre please. kitna sudhar hua h biologics lene se ? mai bhut paresan hu is bimari se.
Hello sir I'm suffering from Crohn's desease. Dr. told me for biological theraphy. What I have to do pleases suggest me sir?
I think you should follow his advice. Usually Adalimumab or Infliximab is used
I am suffering from ankolysing spondylitis from 7 years.My body is fully fused. No flexibility. I am just a straight bamboo . Will this injection help me???? If yes then please tell me the name
Frankly speaking, he injections wont make a huge difference in a fused spine. However, it will prevent further fusion and retard or reverse any freshly formed fusion and might deliver some flexibility and significant pain reduction.
can't we stop etanercept Injection if psoriasis is under control ? Please tell sir
Why not? Yes u can. But had I been your doctor, I would have ensured that u are on at least 20-25mg of weekly methotrexate
sir l have periferal spa.amar knee and ankle pain ache.apnake kothay dekhabo.ami howrah belgachia te thaki.l am 52 years old
Kindly whatsapp at 9831336275.. You can get all the detail there. Or you can visit www.rheumatizm.com for more info
Sir I am suffering from Hidradenitis suppurativa from last 4 yeras...I have taken all the antibiotics but now condition is that I am not able to do my normal work.. Doctor is asking to take Adalumab (Humira) or surgery...which one is preferred sir...
Please help..
You should go for a trail of Adalimumab before surgery
Sir i have diagnosed AS only hip joint pain crp 3 and esr 5 can we take biologics. DMRD not control my pain. Saaz ds 3 time a day but no effective
ESR and CRP are decent. Why do you need Biologics. Before taking Biologcis, please check that the pain is not due to any other cause.
@@therheumatologistthejoints8861 thanks sir last 4 month I trying inversion table exercise and now pain are almost controlled.
Sir mere bete ko ankylosing spondylitis hai Dr ne use biologic bole h vo 17 sal ka h kya uske liye ye safe h adali mumab likha h ji
Ekdam safe hai. Jaise video mein kaha gaya hai, TB , Hep B HepC and HIV ka test negative rehna chahiye Adalimumab treatment se pehle
Sir, i am frm bangladesh. I am a RA patient, taking adalimumab injection every month fr last 05 years & salfasalazine 2+0+2 every day fr 01 year along with adalimumab. I scared abt infection & experienceing mild breathing prob. Can i switch to jak inhibitor frm adalimumab or any other option.
It would be helpful, if u reply.
Of course u can switch to JAK Inhibitors. It will be cheap and effective.
@@therheumatologistthejoints8861 thanks sir fr ur response.