Mam if it is in free form ,it gets accumulated in tissues so no use of hemodialysis but at 43.55 u told drugs with high ppb are not effectively removed by haemodialysis😅
@@shantanudixit8330 how is it correct If ppb is low means more free form Means stored in tissue therefore no use of hemodialysis 43:53 mam stated high ppb means less free form and also no use of dialysis To dialysis kab use hoga in both diff scenario mam told no use of dialysis 🤦
Ma'am agar drug blood me rahega to plasma proteins se bind hi rahega after distribution, but hemodialysis to protein bodies ko filter hi nahi karta to fir, hemodialysis se kaise patient treat karenge.🤔
Even when calculating bioavailability we take plasma concentration at different tym periods... Drug in free form might had already entered the organs so even bio availability that we calculate is apparent?
I love all your lectures Ma’am I’m trying to register but I’m finding it so difficult to register I really want to watch all your lectures. Please how can I go about it. I’m a Nigerian med student
Mam when we consider volume distribution we can't use hemodialysis the high volume distribution drugs due to they have high free from which go in tissues but when we take boud protein form we aslo can't hemodialysis because of bound from of drug to plasma.What is right?
We can't do hemodialysis when the drug have more volume of distribution it indicates... It get easily all over the body both blood and tissue.... So more drug is available in the tissue and the bound form in the blood is less, no use of hemodialysis. When the drug have less volume of distribution.... It get constricted to some volume(blood) so bound form is more... Hemodialysis may help.... To remove the drug
I appreciate how hard you tried to simplify things & also repeated same things so many times to make it better understood 🌹
Mam if it is in free form ,it gets accumulated in tissues so no use of hemodialysis but at 43.55 u told drugs with high ppb are not effectively removed by haemodialysis😅
yes,correct answer is what?
Btao na
Sahi to bola mam ne
Tu kya likh rha pahle khud pdh😅
@@shantanudixit8330 how is it correct
If ppb is low means more free form
Means stored in tissue therefore no use of hemodialysis
43:53 mam stated high ppb means less free form and also no use of dialysis
To dialysis kab use hoga in both diff scenario mam told no use of dialysis 🤦
@@adityathroat1959if PPB is high We can go for Heamodylsis (ma'am said by mistakely)
Take all thumbsup mam 👍👍👍👍👍❤️❤️
Thank you, I appreciate your complement
Ma'am agar drug blood me rahega to plasma proteins se bind hi rahega after distribution, but hemodialysis to protein bodies ko filter hi nahi karta to fir, hemodialysis se kaise patient treat karenge.🤔
Bound form disturute hi nai hota ,for distribution it needs to convert into free form 1st
Hnn ye thoda ulta bole hain 1st me then last ko correct kiye hai
Thank you very much mam 🙏🙏🙏
Thank you, I appreciate your complement
Even when calculating bioavailability we take plasma concentration at different tym periods... Drug in free form might had already entered the organs so even bio availability that we calculate is apparent?
I love all your lectures Ma’am I’m trying to register but I’m finding it so difficult to register I really want to watch all your lectures. Please how can I go about it. I’m a Nigerian med student
Good lecture mam
Thank you, I am happy to hear you feel that way
This is very useful mam, thank you mam
Thank you, I appreciate your complement
👍👍👍👍 you deserve it
Bahut badiya mam
Best 👌
Mam when we consider volume distribution we can't use hemodialysis the high volume distribution drugs due to they have high free from which go in tissues but when we take boud protein form we aslo can't hemodialysis because of bound from of drug to plasma.What is right?
We can't do hemodialysis when the drug have more volume of distribution it indicates... It get easily all over the body both blood and tissue.... So more drug is available in the tissue and the bound form in the blood is less, no use of hemodialysis. When the drug have less volume of distribution.... It get constricted to some volume(blood) so bound form is more... Hemodialysis may help.... To remove the drug
@@lavender2910 but mam also says hemodialysis difficult in protein bound from
how much volume of distribution is considered as high and what range is low mam
Will ph of blood doesn't effect the distribution.... As like absortion and ionization
😅
Is there any notes for this lectures, if there... Then where we can get it?
😍😍😍😍😍😍😍😍😍from ethiopia
Any one have lecture notes
❤❤
👌👌👌👌👌
Thank you, I appreciate your complement
How we'll know the drugs is in free form or bound
Bound form is combined with protein
Thank you mam 💝
❤
👍👍👍
Thank you, I am happy to hear you feel that way
😊
👍
Thank you, I appreciate your complement
😍😍😍
Thank you, I appreciate your complement
👍 👍
👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍👍
1+1=2 ok...givr me thumbs up
Thank you sooo Much
👍
Thank you, I appreciate your complement
👍👍
Thank you, I appreciate your complement..
thank you Mam❤
👍
Thank you mam ❤