I was a bit uncertain about the description of how norepinephrine gets into the blood as a hormone...extra norepinephrine leaked from sympathetic nervous system? Is this because the adrenal medulla is neuroendocrine? Overall I’m really enjoying the videos as a lazy way to review these topics. Thanks very much for putting these together- you’ve put in a lot of work.
I'm glad to hear you are enjoying these videos. They were a tremendous undertaking as I had to make all of the images myself. Some of the blood norepinephrine does indeed come from the adrenal medulla as you mentioned. However most of it comes from sympathetic neuron spillover. See the link below or look up norepinephrine spillove to learn more. www.cvphysiology.com/Blood%20Pressure/BP018#:~:text=Norepinephrine%20is%20also%20released%20by,sympathetic%20nerves%20innervating%20blood%20vessels.
Vivo Phys - Evan Matthews The images are great and I appreciate your way of describing topics. Thanks for the info about norepinephrine spillover...it was interesting to delve into a bit. I had no idea that most of the norepinephrine in our blood arises this way...and mostly from the lungs, if I understood what I read correctly. So much to learn :)
Hello, great layout of basics of hormones to lead into the mechanics of hormonal regulation during exercise. In 19:24, I wasn't clear on whether the 30-45 minutes post exercise means that after you stopped exercising or is it the time of exercise at 30-45 minutes. If I'm following what you are saying, that means that fat burning takes place after 30 minutes of exercise? Also, when you say Glut4 transporter, does that mean it acts like a carrier for glucose during exercise, so that insulin doesn't need to be used as much, because the sugar is being carried into the cell to be metabolized? Does that also mean that the receptors for glucose are being more "open" w/o no to little presence of insulin? Thank you in advance!
Hi Kala Health & Wellness. The general timelines presented in this lecture are referring to what the hormone levels would be if you exercised then stopped and measured those hormones 30-45 minutes after you stop. You would then have to compare the values to your pre-exercise levels. So what this means is that lipolysis is still elevated for awhile after you stop exercising. Yes, exercise can activate the GLUT4 glucose transporter to bring glucose into the muscle cell even when minimal insulin is around.
@@VivoPhys Thank you for explaining the time frame. That word Glut4 transporter makes me think it binds to glucose. But I found this video, and it looks like that Glut 4 inside the cell, pushes the cell membrane so that it's more permeable for glucose to enter. What are your thoughts? ruclips.net/video/9UVl4HQ2V1Q/видео.html
Hi The Symphony of Science. Are you referring to GLUT4 activation by muscle contraction? If you are referring to something else please add a more detailed comment to help everyone better understand the material. Thanks!
Great video, some really in-depth content here that's genuinely new to me, thank you for the upload (appreciate this is not a new upload!)
You're very welcome!
This was incredibly helpful! Very straight forward, clear and informative. Thank you!
You are very welcome.
Thank you very much for this awesome video 🙏
Happy to help.
Good information and presentation Dr. Mat. I learned a lot.
Thank you
Thank you for your wonderfull work.
Thank you for the feedback!
Amazing .the coherence in your lec .
Wonderful
I'm glad it helped!
@@VivoPhys ben seni r çok zor
Thank you so much..very nicely explained
I'm glad it helped.
very helpful
I'm glad you think so.
I was a bit uncertain about the description of how norepinephrine gets into the blood as a hormone...extra norepinephrine leaked from sympathetic nervous system? Is this because the adrenal medulla is neuroendocrine? Overall I’m really enjoying the videos as a lazy way to review these topics. Thanks very much for putting these together- you’ve put in a lot of work.
I'm glad to hear you are enjoying these videos. They were a tremendous undertaking as I had to make all of the images myself. Some of the blood norepinephrine does indeed come from the adrenal medulla as you mentioned. However most of it comes from sympathetic neuron spillover. See the link below or look up norepinephrine spillove to learn more. www.cvphysiology.com/Blood%20Pressure/BP018#:~:text=Norepinephrine%20is%20also%20released%20by,sympathetic%20nerves%20innervating%20blood%20vessels.
Vivo Phys - Evan Matthews The images are great and I appreciate your way of describing topics. Thanks for the info about norepinephrine spillover...it was interesting to delve into a bit. I had no idea that most of the norepinephrine in our blood arises this way...and mostly from the lungs, if I understood what I read correctly. So much to learn :)
thank you so much it helped
Hello, great layout of basics of hormones to lead into the mechanics of hormonal regulation during exercise.
In 19:24, I wasn't clear on whether the 30-45 minutes post exercise means that after you stopped exercising or is it the time of exercise at 30-45 minutes. If I'm following what you are saying, that means that fat burning takes place after 30 minutes of exercise?
Also, when you say Glut4 transporter, does that mean it acts like a carrier for glucose during exercise, so that insulin doesn't need to be used as much, because the sugar is being carried into the cell to be metabolized?
Does that also mean that the receptors for glucose are being more "open" w/o no to little presence of insulin?
Thank you in advance!
Hi Kala Health & Wellness. The general timelines presented in this lecture are referring to what the hormone levels would be if you exercised then stopped and measured those hormones 30-45 minutes after you stop. You would then have to compare the values to your pre-exercise levels. So what this means is that lipolysis is still elevated for awhile after you stop exercising.
Yes, exercise can activate the GLUT4 glucose transporter to bring glucose into the muscle cell even when minimal insulin is around.
@@VivoPhys Thank you for explaining the time frame.
That word Glut4 transporter makes me think it binds to glucose. But I found this video, and it looks like that Glut 4 inside the cell, pushes the cell membrane so that it's more permeable for glucose to enter.
What are your thoughts?
ruclips.net/video/9UVl4HQ2V1Q/видео.html
Muscle have glucose transporters that work WITHOUT insulin bro. That's why diabetics' muscles are fine.
Hi The Symphony of Science. Are you referring to GLUT4 activation by muscle contraction? If you are referring to something else please add a more detailed comment to help everyone better understand the material. Thanks!