QUESTION............Could you have put some kind of protecting group on the carboxy group on the salicylic acid???????????????????????? The only protecting group i know for a carboxy group is to turn it into an ester. But then you could not hydrolyze your protecting group ester with out hydrolyzing the ester you wanted to make
QUESTION.........I take it using the acid anhydride gives a better yield because no water is made?????? What if you just had salicylic acid in the pot with some sulfuric acid catalyst..........would the salicylic acid react with another salicylic acid to form an ester?????????? WOE.......Why did you use folic acid as the catalyst?????????? Never saw that before. Is it because you used anhydride (acetic) and the sulfuric acid will destroy the acetic anhydride?????????? Did you use acetic ANHYDRIDE because salicylic acid has a carboxy group and so you want the acetic acid more reactive than the carboxy group on the salicylic acid so you used acetic ANHYDRIDE???????????????? Why such a low yield????????? Was it just cause you had to film everything or something else???????????? I know having to film can make a yield go down.
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GREAT VIDEO
Thank you for this video! So very helpful
could you use a bunsen intead of an oven? I don't think my college has an oven...
Great video!
LOVIN IT
QUESTION............Could you have put some kind of protecting group on the carboxy group on the salicylic acid???????????????????????? The only protecting group i know for a carboxy group is to turn it into an ester. But then you could not hydrolyze your protecting group ester with out hydrolyzing the ester you wanted to make
QUESTION.........I take it using the acid anhydride gives a better yield because no water is made?????? What if you just had salicylic acid in the pot with some sulfuric acid catalyst..........would the salicylic acid react with another salicylic acid to form an ester?????????? WOE.......Why did you use folic acid as the catalyst?????????? Never saw that before. Is it because you used anhydride (acetic) and the sulfuric acid will destroy the acetic anhydride?????????? Did you use acetic ANHYDRIDE because salicylic acid has a carboxy group and so you want the acetic acid more reactive than the carboxy group on the salicylic acid so you used acetic ANHYDRIDE???????????????? Why such a low yield????????? Was it just cause you had to film everything or something else???????????? I know having to film can make a yield go down.