How Gene Editing is Changing our Lives | Michael Böttcher | TEDxUniHalle
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- Опубликовано: 16 июн 2024
- Cancer is a group of diseases that is driven by genetic alterations, so called DNA mutations, which accumulate in our cells throughout our entire life. Over the past two decades, researchers have compiled a comprehensive catalogue of all the mutations that can be found in human cancers. This tremendous effort revealed, that out of the more than twenty-thousand total human genes, only a few hundred are mutated in cancer. The major challenge that lies ahead of us now, is to make functional sense of the identified mutations. This is where the recently discovered CRISPR system comes in. This game-changing biotechnology allows us to reversely engineer any cancer mutation into the genes of cultured human cells, in order to study the mutation’s functional impact in-vitro. In my talk, I will explain how we use precision genome engineering to translate genetic information into novel therapeutic strategies that will ultimately benefit patients that suffer from cancer. Michael Böttcher was born in Riesa and studied biology in Freiburg im Breisgau. He wrote his diploma thesis in Adelaide, Australia during a stay at the university there.
Since April 1, 2019, he has been a newly appointed Junior Professor for Molecular Medicine of Signal Transduction at the Medical Faculty of the Martin Luther University Halle-Wittenberg. He is researching genes that are involved in the development of cancer in close collaboration with scientists from the institutes and clinics of the University Medical Center in Halle and at the Charles Tanford Protein Center at the University of Halle. So far, he has worked as a scientist at the Max Planck Institute for Infection Biology in Berlin, where he worked in the laboratory of Prof. Dr. Emmanuelle Charpentier, one of the discoverers of the CRISPR / Cas method.
Among other things, the CRISPR / Cas method, known as gene scissor, with which genes can be removed, inserted, switched on or off, is used in his work. “I started doing this in 2014, when the method was still quite new, at the University of California, San Francisco, where I worked for three years, and developed novel CRISPR screen approaches that allow us to create complex genetic networks to examine functionally today, ” he says.Before that, he did research at the DKFZ in Heidelberg for several years, first as a doctoral candidate and then as a postdoctoral fellow. This talk was given at a TEDx event using the TED conference format but independently organized by a local community. Learn more at www.ted.com/tedx
Please help the patients who are suffering from rare disorders like chorea accantho Cytosis.can gene editing is possible in this case if no then please make it happen soon Sir.
I am suffering from marfan syndrome.
@@crumpfyllc5571what a coincidence I too have marfan!
I am suffering from scleroderma last 13 years can gene editing is possible in my case...
Thanks for info,u r on humanity,is this techno used in this present plandemic?
When will gene therapy for DMD will be approved by FDA Probably?
Depends on what trial it's, the regulation of the laws of introducing new genetic treatment is what's takes the longest on the process.
I wish you perseverance and patience, we are almost there!
Teremos uma Possível cura de Hsv ?
1,2 e outras .♥️😍🙏😍♥️🙏
Deus Abençoe ter uma Cura para Herpes ♥️
Can we give elephants wings? Serious question.
I doubt big mammals can fly even with wings
@LittleDrowskie I'm not well in aerodynamics but I don't think aeroplanes flying could be thought of an example to justify the potential of having elephants flying on support of wings like birds. Even if they get wings on elephants with genetic editing which I think is possible, would have to be trained to fly
Elephants can't fly.
Birds have hollow bones.
Elephants don't have hollow bones.
Designer babies
The scientists and their families aren't the lab rats in these projects. Did they ask for consent or are they lying to patients or stealing DNA.
They can't have our consent because they will do genetic engineering before the child is even born.
On clinics' websites there's messages cheering a future with "no Autism, no ADHD, no Down Syndrome, no Bipolar, no neurodiversity, CRISPR-Cas9 is such a great hope for the future."
How do you think those of us neurodivergent feel knowing we're surrounded by people who wish we didn't exist? Communicating this message out to disabled people, that they wish we didn't exist, is no doubt going to cause severe depression and possibly suicide as we now know with evidence we are not wanted.