you are such a honorable teacher. you have made a student like me have the opportunity to all this beautiful knowledge. you sound so passionate! i really admire how you digest the information!
This man has truly taught me everything I need to know since high school. Thank you for teaching me and giving me an education better than a lot of my professors.
Sir your teaching is exceptional. I have been struggling to find a good and clear explanation of translation all over youtube but couldn't find one. But guess what. I stumbled upon your beautiful and super simple explanation of the same. Thank you so much.
God bless khan academy T.T I'm a visual learner and this is just beyond awesome!! I'm understanding, learning, AND I'm inspired by the passion of this teacher!
I've always had this problem with these sites in ribosome, like what are they exactly and what are they for?- and now it's clear. Sal you are a blessing ♥
I love that every video he does he is as fascinated with the complexities of these structures and processes. Now I pick up plants, give them to friends, and ask, what do you see? If they aren't as passionate and appreciative as this man, I cut them off. What is your name Sir? You are amazing!!
This Teacher's voice is super cool and he clears all my doubts and bdw the only reason I love Khan academy's biology part is due to this Teacher's voice
Brilliant Khan, I preferred that to the last video! You're brilliant, thank you! That was the one step nobody explains well and for weeks I couldn't understand it as even the most detailed books I have just bypassed like 'ahem', or 'anyways'!!! Gold stars and medals for you! ;)
This is wonderful. Thank you for a simplified version of translation. Sometimes i prefer watching these summarized videos than reading a book..But i got a question in relation to the 'E, P, A' sites how is it possible that we have an Exit on the 5' yet the mRNA is run thru the ribosome from 5' 3' direction ..Can you assist on that maybe i missed it
its not a mistake. the E site is on 5' bc the ribosome is moving towards 3' but the codons are still at the same place. so the tRNA which is initially on p site shifts to the E site not bc it is moving towards 5' end but bc the ribosome is moving towards 3' end and the tRNA is still in its position.
Great video, explains tRNA and mRNA interactions so well. My mind can visualize it smoothly now. Also, super interesting fact about the antibiotics at the end!
i think i missed a detail- does the ribosome float around and kind grab tRNA or are they drawn towards it? or what? how does the ribosome come in contact with tRNA?
Thia year I'm gonna take University Entrance Exam and i promise i will do my best, and after that I'm gonna come back here and thanks u cuz u teacher did so much for me ♡
During and after translation, polypeptides may need to be modified before they are biologically active. Post-translational modifications include: removal of translated signal sequences-short tails of amino acids that aid in directing a protein to a specific cellular compartment proper “folding” of the polypeptide and association of multiple polypeptide subunits, often facilitated by chaperone proteins, into a distinct three-dimensional structure proteolytic processing of an inactive polypeptide to release an active protein component, and various chemical modifications (e.g., phosphorylation, methylation, or glycosylation) of individual amino acids.
at 12:11, I think you meant to say "then the A-site will be open for another tRNA carrying an amino acid" instead of "for another amino acid carrying tRNA"!
Guys, I am still puzzled with one question: So we have Chromosomes -> DNA in a nucleus of the cell. Then, we have Translation phase where we get Proteins, but where do Proteins live? Do they live inside the cell (cytoplasm) ? So each cell creates it's own Proteins or each cell creates different proteins and they leave the cell and work 'outside' the cell? And in this case, what is 'outside' the cell? Any material/video, explaining this are more then welcome!
![Felix "Unfair" | [Stray Kids : SKZ-PLAYER]](http://i.ytimg.com/vi/Oswujxm2Ag0/mqdefault.jpg)
If I ever actually become a doctor, I am giving $10,000 to Khan Academy. Hold me to it.
when, not if
Any updates?
you are such a honorable teacher. you have made a student like me have the opportunity to all this beautiful knowledge. you sound so passionate! i really admire how you digest the information!
john tindell I first saw this as you are such a horrible teacher lmao I was about to get super pissed off
Alex Christensen fr lmao
same, i was about to go off hahahah
and its all for free im so happy
Alex Christensen sameeeee
This is so much clearer than my college professor could ever dream of doing. Thanks for saving my education.
I've had headaches for two weeks while my teacher was trying to explain this, and now in 14 minutes it's all clear.. thanks!
always like that
God bless Khan. I literally felt like i was on heroin during my lecture today when the prof was going on about transcription/translaition
Btw, just got an A+ in this course. Praise the Khan.
@@petroslazanis8466 lmao ik it's late but congratulations
@@petroslazanis8466 Congrats man!
Congratulations man
@@anoosha9768 0ⁿⁿ0ⁿⁿⁿ0
Q
This man has truly taught me everything I need to know since high school. Thank you for teaching me and giving me an education better than a lot of my professors.
Not gonna fail molecular bio thanks to this 🙏
hahahha, same here man, does this go into deep enough detail, tho?
MMA king I personally thought it was a great overview but not nearly as in depth as our class is going, great for generally understanding it though
U r so pretty, are u Malaysian?
seominty U are so pretty, are u Malaysian?
MMA king lol! That's a k pop idol, not me
Good old Sal! Love his voice. These vids got me through my nursing prerequisites. Couldn't have done it without him. This is gold.
Hands down the best possible explanation I have ever heard. You are a blessing to mankind. Thank you.
This is the most clearly explained video on translation I have watched. Simplifies the complex concept. Thank you Khan Academy and the tutor.
Sir your teaching is exceptional. I have been struggling to find a good and clear explanation of translation all over youtube but couldn't find one. But guess what. I stumbled upon your beautiful and super simple explanation of the same. Thank you so much.
God bless khan academy T.T I'm a visual learner and this is just beyond awesome!! I'm understanding, learning, AND I'm inspired by the passion of this teacher!
I've always had this problem with these sites in ribosome, like what are they exactly and what are they for?- and now it's clear. Sal you are a blessing ♥
THANK U! My brain was frying up trying to understand this by myself.
like what did happened 2 me 😭
Me too..
bro you are the only reason that I have not failed hon bio thank you for that
Why does it look soo simple here😳❤️❤️
I love that every video he does he is as fascinated with the complexities of these structures and processes. Now I pick up plants, give them to friends, and ask, what do you see? If they aren't as passionate and appreciative as this man, I cut them off.
What is your name Sir? You are amazing!!
i love you for making these videos. such a life saver
Life saver as always. Thanks Sal khan!!!
10:39 AA,PE,EEEE sites that got me bro 🤣
This Teacher's voice is super cool and he clears all my doubts and bdw the only reason I love Khan academy's biology part is due to this Teacher's voice
It is Sal Khan himself, who started with online math tuttorials for his relative once upon a time.
Great video, I will definitely pass my Cell Bio exam tomorrow!
Grace Gable did u pass? :p
Grace Gable 😀😁😁you have to score
if I passed my premedical year I would dedicate my certificate to you
Zainab Al Radi did u pass? :p
Zainab Al Radi gimme ur certificate!
beautful structures!!! i love bio.. very facinating
This should be the best bio class I've ever had
Brilliant Khan, I preferred that to the last video! You're brilliant, thank you! That was the one step nobody explains well and for weeks I couldn't understand it as even the most detailed books I have just bypassed like 'ahem', or 'anyways'!!! Gold stars and medals for you! ;)
20 fewer pages of my $150 textbook I will have to read tonight. Thank you good sir.
what we would do without teachers like you? forever indebted to the technology advancement and teachers like you.
WOW... My professor took TOO LONG to explain this. I needed the visuals
Many things missing as per NEET syllabus. But still helped me. Thanks.
This is so awesome and so clear!! You made this fascinating process come to life and this video wasn’t even animated!! Thank you sir for all you do!!
Top Tier explanation. Thank you so much. My book messed up this explanation even if it is quite simple.
it's helped a lot thanks you just got a new subscriber
You are so good! Thank you for making this video.
I did not expect that video to go in enough depth for my intro to cell bio exam but it did! Thanks so much!
waaawo hates off sir, thank you so much, you are a true blessing to mankind,
bless him and this channel
Sal Khan you are a magnificent human being.
🍔 Hamburger like..... I am hungry now.....3:53 😂😂😂
crazy how in 15 minutes i learned more than from a 55 minute lecture
God bless you and all your team
Well done khan academy 👍👍👍👍👍
Thanks won't be enough ... I have understand more then the usual when I follow my boring teachers 💜✨
Who is here to revise for his bac?
Best explanation ever👏
Thank you for teaching us how to love and appreciate biology ❤❤❤
make a nobel prize for education, and give it to this man.
Thank u soo much... Ur explanation nd teaching method is awesome.... I loved it... Nd I'm never gonna forget this...😉
You're a life saver thank you.
Saving my life yet again :)
i wish you go to heaven man wherever its is love from iraq ❤ medicine university
Thank you so much! You are way better than my teachers in explaining!
At this point I should be paying khan academy for my education
Thanks sir
I tried to learn Translation but failed…
But your video has cleared all my concepts about translation.😊
May God bless you
This is wonderful. Thank you for a simplified version of translation. Sometimes i prefer watching these summarized videos than reading a book..But i got a question in relation to the 'E, P, A' sites how is it possible that we have an Exit on the 5' yet the mRNA is run thru the ribosome from 5' 3' direction ..Can you assist on that maybe i missed it
I think it is a mistake, the 5-3 direction should be opposite in that video to make sense. Evrything else seems to be okay.
its not a mistake. the E site is on 5' bc the ribosome is moving towards 3' but the codons are still at the same place. so the tRNA which is initially on p site shifts to the E site not bc it is moving towards 5' end but bc the ribosome is moving towards 3' end and the tRNA is still in its position.
I just realized I am rewatching a video my teacher played for us yesterday. Lol. I didn't realize till the T and + confusion.
The best possible explanation u gave
Hands up to this
So, theoretically all proteins start with Methionine?
Pavel Lambracht Yep. Without AUG, no translation occurs and no protein formed.
Wow. I didn't realize that.
*BRAIN FART* :D
Most of the proteins loose the methionine residue in post-translation processing.
In eukaryotic cells and Archea. Prokaryotes use a variant called fMet
That's exactly what I thought about, and I think you are correct.
Great video, explains tRNA and mRNA interactions so well. My mind can visualize it smoothly now. Also, super interesting fact about the antibiotics at the end!
legendary biology teacher
thank you!! got an exam today and it is on this!!
did you pass
Than you SO MUCH for making this video!!! This helps a lot!!!
i find this whole process so fascinating thanks for the video its clear u are very passionate
i think i missed a detail- does the ribosome float around and kind grab tRNA or are they drawn towards it? or what? how does the ribosome come in contact with tRNA?
You teach a lot better than my biochemistry professor! Class is pretty much useless for me
Thia year I'm gonna take University Entrance Exam and i promise i will do my best, and after that I'm gonna come back here and thanks u cuz u teacher did so much for me ♡
how was it
During and after translation, polypeptides may need to be modified before they are biologically active. Post-translational modifications include:
removal of translated signal sequences-short tails of amino acids that aid in directing a protein to a specific cellular compartment
proper “folding” of the polypeptide and association of multiple polypeptide subunits, often facilitated by chaperone proteins, into a distinct three-dimensional structure
proteolytic processing of an inactive polypeptide to release an active protein component, and
various chemical modifications (e.g., phosphorylation, methylation, or glycosylation) of individual amino acids.
Wow cant believe i actually enjoyed science😂 great teaching
That part at the end about how abx work blew my mind
You are the best ❤️
You guys make it all so much more beautiful. Thanks Khan Academy, I'll do well thanks to you.
The explanation is just wow
Thank you for being a life saver~~ 🖤
Nice video. Some people may not know but proteins make up the majority of the biopharmaceutical market for use as a therapeutic
Thanks alot.. that's so helpfull 👌👍👍
Super helpful I now fully understand
Thank You, Sal!
Awesome! Thank you
taught very nicely...really😀😁😁💕
Thank you so much!!!!
Very nice Video...Thank you so much for This
Brilliant sir Salman khan😍
From Bangladesh!
Thank you Sir.
You are always a Life Saver in Exam
we can do this fellow learners!
at 12:11, I think you meant to say "then the A-site will be open for another tRNA carrying an amino acid" instead of "for another amino acid carrying tRNA"!
Thanks! This video is really helpful!
Guys, I am still puzzled with one question: So we have Chromosomes -> DNA in a nucleus of the cell. Then, we have Translation phase where we get Proteins, but where do Proteins live? Do they live inside the cell (cytoplasm) ? So each cell creates it's own Proteins or each cell creates different proteins and they leave the cell and work 'outside' the cell? And in this case, what is 'outside' the cell? Any material/video, explaining this are more then welcome!
Very informative video
awesome. i really got it now perfectly.
So well explained 👌
you are beyond genius 🙏🌹
You are a great teacher😍
you guys are amazing and extremely helpful
this really help a lot thanks
complicated process it's a whole process how does it know to do that its amazing
This means the whole polypeptide chain binds to a new tRNA at A site every time and the older tRNA they were attached to gets disposed through E site
god bless your soul
this was SO helpful thank u
You are Amazing. Thank you so much 😊
this stuff blows my mind
This is cool and helpful ❤