Citric Acid Cycle

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  • Опубликовано: 13 авг 2014
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    Website link: www.aklectures.com

Комментарии • 107

  • @TMHTNN
    @TMHTNN 9 лет назад +120

    Your style of lecture and presentation of the information in the background whiteboard is by far the most effective out of all the lectures I've seen. You got something great here.

    • @AKLECTURES
      @AKLECTURES  9 лет назад +49

      TMHTNN Thank you, I appreciate the positive feedback! It takes a while to get the notes together and transcribe them onto the board, so its wonderful to hear that you're enjoying this form of lecturing :)

  • @aliciachen9750
    @aliciachen9750 8 лет назад +34

    out of all the lectures on tca i've seen on youtube this was by far the most helpful- not only did you cover the information needed to understand the tca but you're also prob the only person who explained why the steps are happening so well!

    • @AKLECTURES
      @AKLECTURES  8 лет назад +3

      +Alicia Chen Thanks Alicia, appreciate that :)

    • @ILikeToRawrr
      @ILikeToRawrr 7 лет назад

      You are amazing! This has helped a lott! I have a question if you can please answer.. our professor didn't really explain this but it is often in the exam: when you mark a carbon in oxaloacetate 14C, at the end of the CAC, which carbon will be marked? thank youu

  • @vanessasem6344
    @vanessasem6344 4 года назад +3

    I DON'T KNOW HOW I LIVE WITHOUT YOU!!!! YOU SAVE MY LIFE

  • @Ssquatch_28
    @Ssquatch_28 7 лет назад +8

    This guy makes reviewing biochem a breeze. I love it! 👏👏👏

  • @christopherrichard9455
    @christopherrichard9455 4 года назад +1

    ok can i just say how comprehensive he is and how WELL he knows his biology? I listened to it in full, then I listened to it at .75 speed to take notes. I really am liking this guy

  • @victorneves6321
    @victorneves6321 5 лет назад +2

    I love your methodology! Just adding a little errata! Your form 3 NADH + H+ so the net balance of H+ are equal to 6 instead of 4

  • @MuhammadRashid-gq6rb
    @MuhammadRashid-gq6rb 8 лет назад +7

    Hi,
    Thank you so much for your presentation. It's absolutely fantastic and mind blowing. God bless you.

  • @sarahnicolas3301
    @sarahnicolas3301 7 лет назад +38

    Wouldn't you have 6 H+ ions since you get it from steps 3, 4 and 8?

  • @asinx6665
    @asinx6665 8 лет назад +1

    dude your lectures are so so underrated, your notes are very helpful and easy to understand...exposure is whats missing here i think your notes can help a lot of people..

  • @yamilealvarez8817
    @yamilealvarez8817 7 лет назад

    Congrats! Absolutely great, sublime, the best thing I have seen regarding this topic.

  • @vanhooligan7532
    @vanhooligan7532 7 лет назад +2

    I'm such a nerd, because I could listen to this all day! Thank you! Explained very well :)

  • @shasha3able
    @shasha3able 6 лет назад

    I really appreciate the work that you have put into this. If it wasn't for you I wouldn't be able to grasp a full understanding of these. I learn from your presentations and feel a real sense of accomplishment. Because of this I feel more confident in class. Cheers so much!

  • @catalinstoicescu
    @catalinstoicescu 7 лет назад

    All your videos explain better than every other sources I found. Thanks alot for it

  • @erinking4593
    @erinking4593 9 лет назад

    Thank you so much for doing this video and the others! They have been so helpful for the online classes I am taking for my nutrition masters. I appreciate your teaching style, and how you go step by step and everything fits on one board! : ) Thank you!

  • @junczhang
    @junczhang 8 лет назад +9

    your lectures should have more views!!

  • @bzbernier1
    @bzbernier1 7 лет назад +1

    love your lectures. really helping me in med school! thank you!

  • @folak8014
    @folak8014 8 лет назад

    I LOVE YOU!

  • @bangsfpvsessions7972
    @bangsfpvsessions7972 8 лет назад

    I enjoyed your concise lecture as well as the others you've made. Direct to the point and easy to retain and understand. Keep up the great work

  • @silee526
    @silee526 6 лет назад

    You're the Goljan of biochem. Thank you for breaking it down to such friendly terms AK Lectures.

  • @Meanlolvirgo
    @Meanlolvirgo 6 лет назад

    it's insane how much better this helped me understand vs. how my professor teachers THANK YOU!

  • @evannybaddy9303
    @evannybaddy9303 7 лет назад +2

    woow..great video thank you and God bless you

  • @eduardomariscal3927
    @eduardomariscal3927 7 лет назад

    Very helpful lectures. Certainly has helped me make sense of this stuff.

  • @thusomekgwe
    @thusomekgwe Год назад

    Phenomenal. Very phenomenal . God bless you brother .

  • @radio146
    @radio146 7 лет назад

    I can't hank you enough.. This just shows that there is no hard material, but there is only bad professors......... Thank you for making this so clear!!

  • @liberty7405
    @liberty7405 4 года назад

    Your black Board style and the way you speak is excellent sir...

  • @karmenalasaad97
    @karmenalasaad97 7 лет назад

    All your videos are Amazing with great explanation!! You make everything so understandable,,,thank you so much

  • @Eli_1412
    @Eli_1412 3 года назад

    Truly grateful for all of your lectures:)

  • @paulngunja1949
    @paulngunja1949 2 года назад

    You're the best at what you do

  • @cleophussilverman6477
    @cleophussilverman6477 7 лет назад

    Consider your subscription number to be +1 sir! This explanation is so SIMPLE yet so detailed. One of the best explanations I've seen and heard.

  • @woofox333
    @woofox333 8 лет назад

    thank you so much!! your teaching style is amazing!!!

  • @jalapenopoppers9607
    @jalapenopoppers9607 4 года назад

    Great lecture! Really helped with my hs bio class :)

  • @anitasinha9674
    @anitasinha9674 5 лет назад

    you are the best teacher in the world. Thank you so much!

  • @liv.m5730
    @liv.m5730 3 месяца назад

    i just learned more in 13 minutes than I have all semester . THANK YOU 🩷

  • @yikes947
    @yikes947 2 года назад

    Thank you so much for the informative lectures! I really truly do appreciate your efforts and hope to support you in the future with anything i can!!

  • @azanda02
    @azanda02 5 лет назад +2

    Awesome video. I think the total number of H+ is 6 per 1 glucose molecule.

  • @madiiha90
    @madiiha90 8 лет назад +4

    AK i love your lectures! SO many have helped me while preparing for my USMLE step 1! but in regards to the TCA cycle, I have a question, why are there are total of 4H+ per glucose molecule rather than 6? Isnt one H+ produced with each NADH?

  • @najmaalisharif5898
    @najmaalisharif5898 7 лет назад

    thank you so much
    your lectures are very easy to understand and helpful too
    keep doing what you do

  • @vijayalakshmivijayalakshmi1715
    @vijayalakshmivijayalakshmi1715 5 лет назад

    I'm preparing for csir net exam..the way u teach via the handwritten notes makes easy to understand..the concept are cut clear.. obviously lehninger

  • @kishanKumar-uw3bz
    @kishanKumar-uw3bz 7 лет назад

    Awesome lecture mr ak

  • @TheToxicMegacolon
    @TheToxicMegacolon 6 лет назад

    Great video

  • @yenyseldiaz237
    @yenyseldiaz237 7 лет назад

    excellent video!!!

  • @zuhayphayaanyuusuf3369
    @zuhayphayaanyuusuf3369 2 года назад

    You explained Very well

  • @obizzy9909
    @obizzy9909 8 лет назад

    Thank a lot your lectures help me a lot in my exams

  • @besttattooartistjhansi812
    @besttattooartistjhansi812 5 лет назад

    Thank you so much for this .. Krebs cycle explaination ..

  • @shafwanmohammed528
    @shafwanmohammed528 8 лет назад +1

    the best...👍👍👌👌

  • @steveo6728
    @steveo6728 4 года назад

    What do those arrows indicate, specifically those that curve down or up or to the right or to the left side?

  • @mimozaqueen5216
    @mimozaqueen5216 7 лет назад +1

    your way of learning is great but just a small remarque if your vedios was shorter may be better to not feel boring .... perfect job thank you

  • @edrussell8650
    @edrussell8650 5 лет назад +1

    Great lecture! Very clearly explained. My only Q concerns the H+ IN STEP 8. That H+ does not get tallied in the final product count. The final product has 4H+ (2 *2H+) from steps 3 and 4, but there is an additional H+ formed in step 8. Q: Why don't we include this H+ as a product, making the total H+ formed 6H+?

  • @michaelallen5988
    @michaelallen5988 9 лет назад

    Thanks bro, my friend and I are reading physics with sports science at university in England and have found your lectures to be a great help!

    • @AKLECTURES
      @AKLECTURES  9 лет назад +1

      Michael Allen thats a great concentration! glad to hear it, happy that I could be of help :)

  • @N20177
    @N20177 8 лет назад

    OMG YESSSS THANK YOU!!

  • @namimiyagi857
    @namimiyagi857 6 лет назад

    Thank you so much ypu're the best

  • @105soccerlover
    @105soccerlover 8 лет назад +10

    Why don't you count for the other H+ ion that is produced in the last step? You said we have 6 NADH, so shouldn't we also have 6 H+? From steps 3, 4 & 8?

    • @yasminabenrahal7370
      @yasminabenrahal7370 8 лет назад

      +Sigrid Kite i have the same question even in my book i found the same thing

    • @Cali_Beast_Sesh
      @Cali_Beast_Sesh 7 лет назад +1

      +Sigrid Kite You are right, but I think he knows that for sure and probably forgot to mention it or just missed it. It happens sometimes :). However I think this man (AK Lectures) did his job perfectly!

  • @rebeccabartke6896
    @rebeccabartke6896 9 лет назад

    This is a great source for reviewing, as well as learning for the first time! Thanks for the time you invest in making these videos (: Do you have a video where you also go in depth about the mechanisms behind each of the enzymes in the TCA cycle, by any chance?

    • @AKLECTURES
      @AKLECTURES  9 лет назад +2

      Rebecca Bartke Thanks Rebecca. This lecture was a biology lecture and so it was not meant to be in-depth. But I am currently working on biochemistry and am planning on making a lecture on that, so definitely stay tuned.

    • @AKLECTURES
      @AKLECTURES  9 лет назад

      Rebecca Bartke Also Rebecca, I think you asked about playlists a while back so I managed to organize some. I will continue organizing the biochemistry ones into specific chapters and such.

  • @kitonyphilemon3577
    @kitonyphilemon3577 8 лет назад +1

    guys a medical student at university of egerton kenya.presentation fantastic.how many co2 molecules in two turns

  • @nutritionalbiochemistry9766
    @nutritionalbiochemistry9766 4 года назад

    I am really really really thankful to you sir allah bless you a lot in the world as well as in the next world of always be remaining

  • @meihuiliu262
    @meihuiliu262 7 лет назад +1

    I have a qn: succinyl CoA doesn't have a phosphate so where does the phosphate comes from?

  • @tutalta4523
    @tutalta4523 2 года назад

    THE BEST EVER

  • @nirpeshdhakal8085
    @nirpeshdhakal8085 7 лет назад

    Is it same CoA that migrates from PDH complex to @-ketoDH complex after getting kicked out from Acetyl CoA or each of these complexes have their own CoA?

  • @ImtooFuturistic
    @ImtooFuturistic 8 лет назад

    Can you do a short lecture on glyoxylate cycle?

  • @promisendlovu8550
    @promisendlovu8550 8 лет назад

    l cant believe dat lm now one of de brilliant students in class because of these videos..............thank you very much sir !!!!

  • @narasimhrao2358
    @narasimhrao2358 9 лет назад

    Thxx u so much

  • @mohmedhamdan2539
    @mohmedhamdan2539 6 лет назад

    Thanks sir i don't know how to say thank you you you are awesome

  • @entertainmentworld3397
    @entertainmentworld3397 Год назад

    Very Nice

  • @sajjadalimi2106
    @sajjadalimi2106 8 лет назад

    In the process of glycolysis link reaction and citric acid an (overall) 8 NADH+ H+ and 2 FADH2 is produced, this happens in a reaction where NAD+ 2H+ +2e and FAD --> FADH2, This meaning, when prodcuing 8 and 2 of these electron carriers we need 24 hydrogen, but glucose only has 12 hydrogens so where do these 12 other hydrogens come from if it does come from glucose cause it simply doest have that many hydrogens, does it come from water that is used in krebs cycle or i dont know ..please help me

  • @sciencenerd7639
    @sciencenerd7639 3 года назад

    thank you

  • @taniamukherjee8590
    @taniamukherjee8590 5 лет назад +1

    Can you explain why there are only 2 coA produced? Shouldn't there by 2 more from the first step where OAA reacts with water to decarboxylate acetyl coA? There is a coA produced in that step. Also is there a net input of 4 molecules of H2O?

  • @FANguyen
    @FANguyen 6 лет назад

    I think there would be 6 hydride molecules H+ produced in the CA cycle since there are 3 of them produced in step 3,4, and 8 in each of two cylces. Any explanation here ?

  • @sosabra7597
    @sosabra7597 7 лет назад

    you have agreat method to explain lectures

  • @muskaanmemon8475
    @muskaanmemon8475 6 лет назад

    Can you explain the significance of Krebs cycle? And how does it play a catabolic and anabolic role?

  • @zakayo100
    @zakayo100 8 лет назад

    please help: Explain where in the CAC a hypothetical defect of an enzyme could occur that would decrease the overall ATP production of the mitochondria, including each of the following:
    ● whether the entire cycle will continue to function
    ● what will happen to the cycle products
    ● why ATP production decreases

  • @addictivearsenal6338
    @addictivearsenal6338 4 года назад

    that's why I skip classes tnxs man GOD BLESS U Thanks a lot

  • @hassousaya2683
    @hassousaya2683 5 лет назад

    I’m in luv with u u save my hall life 💛💛😍😍😍

  • @nhanguyenlt7225
    @nhanguyenlt7225 6 лет назад

    my friend said the one who study and teach Biochemistry is an artist, we all have to draw a big picture of the process:)))

  • @ayeshajunaid7075
    @ayeshajunaid7075 7 лет назад

    hey aka can u explain about the very first step of TCA cycle i.e formation acetyl co-a from pyruvate because there is a enzyme complex that is carrying out this reaction which is very difficult to understand

  • @stephengbekor7496
    @stephengbekor7496 8 лет назад

    how many Hydrogen ions are produced finally, 4 or 6?

  • @abhyarthanabehera4802
    @abhyarthanabehera4802 Год назад

    So you have said that we make 6C citrate because we need decarboxylation. But why do we need to release two CO2 molecules?

  • @kishanKumar-uw3bz
    @kishanKumar-uw3bz 7 лет назад

    Hey AK will you please give me notes on zoogeography please

  • @sara43
    @sara43 8 лет назад +1

    you so good and rare

  • @humashahper1759
    @humashahper1759 3 года назад

    Please upload lecture on biochemistry of nitrogen fixation.

  • @ElohoFuture
    @ElohoFuture Месяц назад

    Sir, I can't see clearly what you wrote on the board😢😢
    But the explanation was superb 😊

  • @jakedo2462
    @jakedo2462 5 лет назад

    how is that circle so perfect...

  • @kishanKumar-uw3bz
    @kishanKumar-uw3bz 7 лет назад

    Hey AK I want to talk with you

  • @adaurooj7362
    @adaurooj7362 8 лет назад

    My book says there are 4 NADH produced per acyl-CoA.. which means 4×3=12 ATPs are produced during TCA...

    • @JOAT22
      @JOAT22 6 лет назад

      its always been 3NADHs giving 9 ATP

  • @luvnsmile4ever
    @luvnsmile4ever 8 лет назад

    hey! there should be 6H+ released by the CAC, not 4H+

  • @Docfahjr
    @Docfahjr 7 лет назад

    I thought it was pyruvate dehydrogenase that converts pyruvate into acetylCoA

  • @goolkeepergolar8913
    @goolkeepergolar8913 6 лет назад

    why two colour lectures for the same thing

  • @silee526
    @silee526 6 лет назад

    I'll watch it over until all that fine print is part of my subconscious

  • @Shadow12aven
    @Shadow12aven 2 месяца назад

    I think you have 6 H+, there are three protons, not two.

  • @marianorgr
    @marianorgr 6 лет назад

    I'll pass biochem with the best score posible, promise.

  • @broccoli3978
    @broccoli3978 5 лет назад +1

    Marry me, please!

    • @nguiphilip1996
      @nguiphilip1996 4 года назад

      gorgeous give something as gift please he deserves more than that

  • @clivepearsall6616
    @clivepearsall6616 3 года назад

    What a truly very annoying voice this man has. I was immediately 'turned-off', as it were.

  • @mimozaqueen5216
    @mimozaqueen5216 7 лет назад +1

    your way of learning is great but just a small remarque if your vedios was shorter may be better to not feel boring .... perfect job thank you

  • @ElohoFuture
    @ElohoFuture Месяц назад

    Sir, I can't see clearly what you wrote on the board😢😢
    But the explanation was superb 😊