Blood Test For Early Alzheimer's Detection!
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- Опубликовано: 26 окт 2024
- Discover the groundbreaking advancements in Alzheimer's disease detection with our deep dive into the potential of blood tests for early diagnosis. With Alzheimer's affecting millions worldwide, the quest for early detection methods has never been more critical. This video explores how recent developments in blood-based biomarkers could revolutionize our approach to diagnosing Alzheimer's, making it quicker, less invasive, and more accessible than ever before. We'll cover the science behind these tests, the benefits of early detection, and what this means for the future of Alzheimer's care.
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In case you haven’t met me, my name is Natali Edmonds and I am a board certified geropsychologist. That means that I am a clinical psychologist who specializes in working with older adults. One day, while hiking a trail, I came up with the idea for Careblazers and I decided to see if posting videos online could provide help to the many other Careblazers in the world who don’t get to have help come directly to them in their homes. I hope that this work helps you in some way on your caregiving journey.
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I originally thought my answer would be yes but after caring for my mom for the past six years, 24/7 with advanced stage Alzheimer’s I don’t think I would want to know. I’ve told my adult kids to never feel badly for having to make a decision for me and that I would want them to live their lives and wouldn’t want to be a burden on them. It’s such a heartbreaking disease, love my mom with all my heart but it is exhausting physically, mentally and emotionally
I feel the same way. I took care of my mom as well. It was exhausting. I never want my kids to have to go through what I did.
@@gennyolson2257 I have never been so physically, mentally and emotionally exhausted in my life and she’s getting lots worse. I’m 65 and disabled so makes it so hard. My adult kids have seen the toll it’s taken on me, both working full time jobs, raising their families and have told them if this happens to me, please don’t ever feel guilty about doing what they need to.. I
Absolutely, I would. My father died of Alzheimer's about a year ago, and my mother is currently in the mid-late stages of dementia. We knew something was not right years ago, but they stubbornly refused to see a doctor, or talk about their options and choices and how we could help. By the time we got the diagnoses, they were in the process of losing their home(we had no idea they stopped making payments on a second mortgage they took out). They had blown through retirement and savings accounts and were all but destitute. Everything was a struggle...getting power of medical attorney, gaining access to financial accounts to help them, making decisions with end of life care and burial. To say it was brutal is putting it mildly. If there was a test that could tell me that was coming down the pike, I would have ability to make choices while I was still cognitively able. I would be able to choose my own care and end of life arrangements, get my kids on my financial accounts so they could monitor and take over when it became necessary. I could have those important talks with my daughters to hopefully eliminate SOME of the incredible stress we experienced with my parents. It's enough stress just to watch a beloved parent decline...the other stuff just makes it harder.
Yes, I would like to get tested. I am a planner. My grandmother died from Alzheimer’s and now I’m taking care of my Mom and she is on the road of dementia. Still waiting on a diagnosis for her. I don’t want to be a burden on anyone. I’m already exhausted trying to take care of my mom. I’m 49 she’s 75. My grandmother died at 81 and had the disease for 10 years. The thought of ten more years of taking care of my mom is frightening.
I am with you Im 53 moms 77 Id want blood test , genes genetics play big part indeed ❤
I understand completely.
I've been taking both of my care of my parents for 2 years
My husband the sixty eight and the things that he cannot remember or starting to concern me..
I know this sounds selfish. But I don't want to spend the last 10 years of my life. Taking care of another alzheimer's/dementia patient.
Yes, me too for testing. My person is my mother in law. She’s 83 and I’m 75. It’s difficult and sad. I want to know before I won’t understand.
@@peggyriley9118 I’m so sorry. 😢 Nobody should have to endure this multiple times.
Yes I think I would do the blood testing rather than the other neurological testing. My mom had Alzheimers.
My grandmother had early onset, and my mother began showing signs over a decade ago. She still hasn’t been diagnosed, but the whole family knows. She can’t be left alone and is progressing quickly. When seeing a doctor is mentioned, she gets very angry and denies having issues.
Unlike her, I spoke to my PCP today about getting in to be evaluated. I’m only 40, but if possible, I’d like some baselines they can have for later down the road. If it’s possible to have a blood test, I will gladly get it done.
Thanks for the info.
Yes, I would welcome the blood testing. My husband currently has some form of dementia (brain atrophy via MRI). Insurance will not approve further definitive testing, (PET) scan. I am an RN with many years of ICU experience. The usual family caregiver does not have this experience.
It is no less difficult for the family of the sufferer, whatever their experience. The care required is very personal & can take some dignity away from the patient, to say the least.
The point I am trying to make may seem a stretch - but I believe it might be helpful to some to know what may be coming in the future. Planning is everything. There must be a plan B in place before chaos ensues. Working on that now. Good luck.❤
Yes I would get the test. Caring for my dad and realising I actually lost Him years before he passed. I definitely would be tested.
Absolutely! My darling mother developed Alzheimer's and Parkinson's. My sister and I are already participating with All of Us Research Program to look into our DNA and find out which diseases we're at risk of developing. This program is free which we appreciate as genome testing can be pricey. A test like this it's going to be great for those of us who want to know.
Dr. Natali, This was a really informative video. Someone else mentioned getting Long-Term Care Insurance before getting tested. I am in agreement with that. You do not want to be turned down for pre-existing conditions. I am also concerned that if some of the health care reforms that were gained are rolled-back, we will once again be denied coverage or care for certain pre-existing conditions. If I could take care of these concerns, I think I would get tested to get any early treatments that might be out there and to plan for the future.
Yes, such blood testing is essential to help family members prepare for the eventuality of dementia. However, a big effect will be on our personal healthcare insurances and the like. Thank you, Dr. Natalie, for helping all caregivers, even here in Singapore!
I believe my neuropsychological testing was a horrible experience. I suffered a widow maker heart attack in 2021. They lost me for 15 minutes. At the hospital they didn’t do any imaging of my brain. They treated me for an anoxia brain injury. Fast forward 2 years later my wife noticed and so have I some deficiencies in my memory so my Dr. set me for a MRI and neuropsychological testing. I scored low in most areas but he put he thought that the test underestimated my abilities. In his notes he stated I didn’t have any evidence of my heart attack or neurological issues and I didn’t score for having anxiety or depression during the testing. But speech therapy would be good. I also had an appointment set up for the KU medical Alzheimer’s and dementia clinic. Again I scored low on the test they gave me. They talked with me and my wife separately and together. They diagnosed me with dementia mild. I start the memory clinic care next month. So yes I would take a blood test. Instead of the 2 1/2 years of going through what I’ve been through. The neuropsychological testing was 8000 dollars so was the MRI with contrast and without. Horrible experience.
Yes. I am getting the blood test---regardless of result I'm hitting the ground with lifestyle changes!. Thank you for this video; it has made me excited about the blood test coming up.
Since it's not decisive either way, what's makes you eager to do it? I'm honestly curious.
Yes , I would be very much interested in blood testing. And I am interested in such informatin as ones in video. Thanks for your efforts and support🥰
Yes I would want to be tested to find out if it's normal aging dementia or Alzheimer's
Yes I'm interested in learning more about new promising treatments.
Read the book...The End of Alzheimers...my husband has it, im giving this book to my kids so they can hopefully prevent it for themselves...lots of great info
thank you so very much for your work
Yes I would!
I was advised that a neuropsych test at age 60 provides a good 'baseline'. Yes, I would get a blood test.
Advised by whom🤔
@@LAppleDumpling
Geriatric neurologist in South Florida. That region is 10-20 years ahead of my little Southern city.
Yes, I would consider it. My family on my dad's side has had it. And it would be good to use as a tool to make future plans . However, would insurance companies rate or penalize you if your markers were present, creating coverage worries.
Yes, my husband was diagnosed with MCI 6 years ago and in the past 6 months is showing decline. Our children all live in other states and we dont want to intrude in there lives to take care of us. So planing for the future is very important. Should we both have the markers for Alzheimer’s we would move into a independent living community that has graduated care. My husband is 79 and I’m 74. Thank you for this informative information.
Our family was told by a funeral director that the chance of having an autopsy for our loved one with dementia was most unlikely. It seems that it is hard to find someone who is interested in doing the autopsy because they don't see it necessary to help a family find out what type of memory disorder their loved one had ( Alzherimers, Lewy Body etc.) , and if they do agree to do it, they find it more worth their time if they charge an overinflated cost for the procedure. I find this very sad. Our loved one's doctor never even thought it necessary to do a PET SCAN or send them for neuro testing. I think this leaves families frustrated and wanting to know what took their loved one from them in the end. The BBB test would certainly give a person a chance ahead of time to prepare for the future and to then know what should be done going forward with their health and planning. I have asked my own GP if as a family member of a person with dementia if I should be doing any baseline testing and she told me that unless I am having noticeable issues that they usually don't refer on for evaluation. AS you say, by the time I would show signs it may be too late to do anything that could really help me.
I feel your pain! My mom died of dementia 2 days ago & when I mentioned autopsy, hospice made it sound like it would be a hassle for them. They said it was going to take a medical examiner & the University of Iowa to get involved. They said it would be ‘out of pocket’. When asked how much (I would have paid a lot) they said thousands.
That’s upsetting as we want to know!
Yes. I would definitely take her test.
Our Neurologist says the blood test is available, but the makers of the test want doctors to perform it in house. Most neurologists don’t have blood labs on site.
Yes very interested in testing and more promising treatments
Yes, I did. I signed up for the AHEAD study. I was rejected due to too low of an amyloid count in my blood. I made lifestyle changes 5 years ago and will continue to enroll in future studies as they become available.
Absolutely, i would get tested. My mom had early on set Alzheimer's, and she also had 3 siblings pass from this same disease.
I am 58 years old and have 2 copies of the APOE e4 variant. I would definitely take the blood test.
Yes, I would rather know. For me it’s always best to know and be able to plan for hard things.
Yes after caring for my husband hope blood test comes real soon!
Absolutely !!
I feel so blessed to be in a part of the country where this testing is available; my LOAFTD had the blood test and it definitely helped to solidify what we saw on her MRI/CY scans and, her test session with our geriatric neuropsychologist.
We had the blood test done at the USF Byrd Alzheimer’s Institute. We were told everything you mentioned regard the test. For us, knowing the A&T levels helped show part of the story; congruent with my LO symptoms, behaviors, imaging and neuropsychological testing. I feel more confident that she has been properly diagnosed.
Absolutely yes.
My hubby does have some dementia behaviour, but gps will not test him. If he did I would apply for attendance allowance, here in UK. It would really help.
Yes, I am interested in knowing more. And yes, I would like to have this test. My grandfather had it.
Yes I am interested in new ideas and yes I would definitely take a blood test!
Wow, that was so much info. I might need to watch a couple times. Yes I would do blood tests.
I am not wanting to spread false information, so please research this further. I am new to researching dementia and, in particular, Alzheimer's, however, when speaking with the Alzheimer's Association, I was warned to avoid blood tests for Alzheimer's. As I understood it, there is a loophole (not sure if that's the correct word), even with HIPAA, that can cause positive results through blood testing to alert health care providers of your high risk. With my mom's recent health issues and having a family history (grandfather and 2 aunts lost their lives as a result of Alzheimer's), I am deeply concerned for my future and am looking into saliva testing that would show indicators such as which APOE genes I have as well as an overall genoscore. Prevention for me currently is exercise and the Mind Mediterranean diet. I would appreciate any further insight as to a blood test.
Interesting. Yes, I would get the test.
Yes I would love to get tested, My Grand Mother had Dementia and my Mother were struggled took care of her, Now Im a care giver for my Mother in Law, since I dont have any kids, Im worry for who in the future will taking care of me,probably my nieces or my youngest Brother. Hope with the test I could prevent and slower in case I positive with Dementia.❤
Yes I would want to know,
Absolutely, I have gone through neuropsych testing and 2 LP's both of which the samples were mishandled. It has been very expensive. I am 53 and in the process of applying for SSDI. Early onset ALZ is a compassionate allowance. If I do have it I want to be able to enjoy what time I have and allow me to plan accordingly.
Definitely. It would help me to plan ahead. I care for my mother who has dementia. It is horrible seeing her like this. I totally don’t want my family to have to go thru this with me. I want to know in advance so that I can prepare. I hate this disease.
My mom and grandmother and two sisters have/had dementia. So I am worried about genetic risk for myself. So I absolutely say yes to the blood test if available.
I would definitely want to know! It takes a lot of time & care to take care of someone like this, so I would want to plan for my future so I will be ok when it gets bad.
Such an exciting video. I would certainly do the blood test. I like to know what is going on in my brain regardless of the results. Its good to know and be able to do something before time. I love your videos they are always full of interesting things. So for me a big yes I would do the BBB test.
Yes I would definitely get the blood test since my family has a history of dementia.
❤Yes I would take the blood test. Thank you for the information.
Yes, i would want to know!
Yes I would.
I'd only get it done after I signed on for LTC insurance.
Yes I would get tested
There’s nothing they can do about it. And what’s if it’s a false positive? Not for me.
Take Benfotiamine supplements and cut out sugar and carbohydrates as much as possible. Some researchers call dementia Type 3 diabetes. Taking these steps can't hurt, might help, and cost very little.
No. They want to take your drivers license away even if you are still a good driver. You need your drivers license to get groceries, go to appointments and social activities. It isn't always convenient to get someone to do these things for you. I know someone who had to take a drivers test just to show proof. Just because someone has beginning dementia does not mean you should go after his/her drivers licence.
I would definitely like to be tested.
I would like to have the blood test AND a Neuropsyche exam. I've been working the lifestyle risk mitigations all along, so I don't know what getting test results would change. I think it would help with planning for our future, though.
Thank you for the Food for Thought, Dr. Natali. ❤
My mom passed last year with Alzheimer’s. After that my primary had me do a blood test. It revealed I have apoe 4 but I don’t know if I inherited one such gene or two. I then went to a neurologist who said that was the wrong test. He sent me for an mri which came back normal and then for a test called Brain Check-done on a computer. I was extremely anxious to do that test (I have always suffered from test anxiety even in school). I only scored an 83. I have been watching my diet lately and added supplements like magnesium L-threonate, doing brain games and trying to improve foreign language skills to stimulate my brain. I really want to improve my chances not to have Alzheimer’s-especially after caring for my mother for several years with this disease and seeing what it did to her. 😢
Read the book The End of Alzheimers. I'm giving this to my kids...my husband has dementia
Yes, I’d get tested. My mom has Alzheimer’s and I don’t want to end up that way. I would want to know early so any treatment would be more effective
My wife has memory loss & the last we seen her neurologist, he mentioned a blood test, but didn't know if Medicare would cover it .We see him in 3 wks, so will see if we can get it done.
I would get the test for myself and recommend to my parents, no question. Early aggressive preventative measures and intervention, advance planning, and significant family history on one parent's chart are all reasons. This parent will not go to neuropsych for eval so the labs would be a lifesaver.
Yes.
Yes I would go get it.
Yes I would get tested.
Straight away.
Yes I would take the blood test...my husband has ALZ FOR 10 YEARS OR MORE.
Yes…..most definitely
Yes
Even though it might not be an accurate test, it may encourage people with the plaque to live a more healthier lifestyle. And as you said, let people know years before the real damage is done...
I think however it might also cause some people to give up on life, it is sooooooo depressing...
It's hard to decide, but myself I would have the blood test, and take any negative outcome as a challenge.
Thanks for the video, and detailed information.
Just been diagnosed via lumber puncture results
yes, I would take a blood test
Always interested. I don't think I would.
Yes I’d take the test
I’m also going to find a neuro psychologist
Yes Id go get it right now if blood test available, nan had Alzheimers & Mom now has Mixed Alz & Vascular Dem Im her care giver so yes Early stage studys intervention prevention Id start as soon as I could , Id get husband tested too as lost his mom August 2023 to vascular Dem her mom had Alzh so we believe genes genetics , we are none smokers so was / our parents,don't eat fast food ,little drink try walk when possible in cold wet british weather not easy, thanks Dr Natali ❤
My husband has had dementia symptoms for about 8 years. He has had psych tests and they showed severe cognitive impairment. I would like to know for sure if it is Alzheimer’s to make sure present treatment is correct. Also, for future generations.
Even though no one in my family has had Alzheimer’s, except my spouse Donnie, I would get the test if it was easy and convenient. However, due to data leaks and theft the tests should probably be some sort anonymous.
Very informative :)
I would
How can blood detect impaired thinking/behavior? How will it change diagnoses & what svcs someone can receive? My LO has uncomplicated ALZ which I equate to dementia... but what does that really mean? Testing brains is just too difficult to find out...
YES INDEED I would since I've been Told that I have Dementia Back in 2019 But I'm Just not sure about it!
Can they detect it in infancy?
I would get tested.
YES, very much so. I try to do as many "brain teaser" games as possible, and eat as much fish as I can.
So how do you get tested. My mom has moderate dementia. I think I may have started it. I loose my car all the time, and a few other things I should know but do not
If someone wants to loose their driving license then yes . Even if you can pass the DMV test and able to take care of yourself at any age .
I’d take it. Grandmothers, two aunts and mother. 2 on each side. I want to know.
Last we were told there isnt really any treatments. So what are you saying? I know lifestyle choices and such can help, but none of the drugs have shown any real efficacy
My Mom and my Grandmother both died from Alzheimers - I am so afraid I will get it also - I don't think I would take the test.
Can you develope
alzheimer if the proteins are found to be borderline by the lab results.??
There are other types of dementia though. It’s not all Alzheimers
Yes I want to know more about mixed Vascular Dementia & Alzheimers , Wonder if 1blood test fits ALL Alzheimers & Dementias ?
I would not. I know how powerful the mind is in influencing the health of the body, and believing I had it would only make me anxious and could contribute to the actual decline (even subconscious beliefs can influence the body). I am doing everything I can now anyway for my brain health, so I'm not sure what would change if I "knew." Unless the test were 100% accurate, AND there was some hope for getting early intervention that would actually help, I'd say no.
To me it sounds like searching for the holy grail currently. To have both false negatives and positives means it will still need the neuropsych testing as it is not at all definitive. To me it sounds very much like testing for ME used to be. Perhaps 7 conditions present the same symptoms, so you have to do the clinical tests that work for 6 of the conditions to rule them out, followed by a more subjective analysis of primary and secondary symptoms to arrive at a diagnosis. Perhaps that has changed by now, but that was the process when I was diagnosed with ME in 2001. I sincerely hope that a fairly definitive blood test for alzheimers becomes possible one day, but if we knew enough about the condition, it's causes etc already then it should be easy. It's not easy imo because we don't yet have the knowledge of how the process initiates and progresses. Why use 2 words when 20 wķill do 😊
You can take a 23 and Me or Ancestry DNA test and download the raw data and look for this genetic variant
this test isn't looking for genes as those DNA tests do. This is looking for evidence of plaques and tau,
@@DementiaCareblazers Oh, sorry, thanks
No, I would not get tested. I want health issues handled first. People treat you different when diagnosed with Dementia. I would wait first to see how well the blood tests works.
Too many variables, to many inaccurate tests NO !