Flocculated: 1. Have loosely packed aggregation called floccules/floccs 2. Faster sedimentation 3. Doesn't form cake after sedimentation 4. Redespersible 5. Clear supernant Deflocculated: 1. Separate entities 2. Slow sedimentation 3. Forms hard cake after sedimentation 4. non - redespersible 5. Cloudy supernant 👍👇
In flocculated suspension, drug particles are entrapped in a network of floccules and their effective surface area exposed to gastrointestinal fluids is reduced. This decreases the dissolution rate of drug particles as per Noyes and Whitney's equation. This is reason why flocculated suspensions have low bio-availability.
The Ideal suspension is, easily redispersible and slowly sediment. But both of class is not met the Ideal suspension. But in overall I thought Flocculated suspension is better.
Flocculated:
1. Have loosely packed aggregation called floccules/floccs
2. Faster sedimentation
3. Doesn't form cake after sedimentation
4. Redespersible
5. Clear supernant
Deflocculated:
1. Separate entities
2. Slow sedimentation
3. Forms hard cake after sedimentation
4. non - redespersible
5. Cloudy supernant
👍👇
Now i have understand about floc & defloc. Thanks for drawing the diagram which makes it easier to understand.
Hello..what kind of software you are using in your presentation ..looks good..
Thank you for your efforts
why bioavailability of deflccutated grter than flocculate suspension
thank you sir. the video really helped.
why does flocculated suspension have low BA, hoping for further explanation :)
In flocculated suspension, drug particles are entrapped in a network of floccules and
their effective surface area exposed to gastrointestinal fluids is reduced. This decreases the dissolution rate of drug particles as per Noyes and Whitney's equation. This is reason why flocculated suspensions have low bio-availability.
The Ideal suspension is, easily redispersible and slowly sediment. But both of class is not met the Ideal suspension. But in overall I thought Flocculated suspension is better.
Thank you very much 😊
Which one is better suspension???
rajib halder flocculated suspension
Deflocculated suspension is more useful than the flocculated suspension
flocculated
thank you
It's very useful
Thank you😇
Thanks sir🙏🏻🙏🏻🙏🏻🙏🏻
Deflocullated types
R u Gujarati ? Ur voice is like that
thank you sir
Thanks
Thnx sir
Explanation is good but u r nothing writting only drawing lines
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