That's amazing Professor, indeed!!! With few details a great information!!! You have already inspired me to design better presentations!!! Thank you very much!!!
I'm studying for my modular exam on Pain right now for my undergrad degree in Psych, and these videos have been super helpful in solidifying my knowledge!
Thank you, Dr. Campbell. You have a gift of breaking down complex material to a very understandable process for the listener. In fact, I found this podcast quite enjoyable. Your speed of delivery is just right, coupled with your clear hand graphics. I will be watching your entire series on pain and pain pathways.
I had a meningioma in the C4 - C6 of my neck vertebrae removed in 2002. It was the size of a gulf ball but the neurosurgeon did not remove it all because it would cause severe damage to my nervous system. The benign tumour grew again, 2013 I had surgery. The area became infected, needed surgery again and had 6 weeks of radiation which caused the most damage. In 4 days time, 11 February 2020, I will be having surgery again for lesions. These video's have been more helpful than any of my GP's, neurologists', pain specialists and registered nurses. Thank you Dr. Campbell. ❤
I have become aware of a shared set of symptoms among people suffering from Spinal and Spinal cord injury, Multiple Sclerosis, Fibromyalgia, Lupus, and other disorders. The pain "matrix" is fascinating and such a worthwhile field of study for those who have a vocation for research.
Thank you for this video. I live with arachnoiditis, so it's really awesome to see this video, well put together and easy for me as a pain patient to understand. I have severe pain. :(
Interesting. I guess that's why snorting cayenne pepper wakes me up so well. The C-fiber to reticular pathway. I started snorting cayenne pepper to desensitize my nasal tissue to airborne irritants, but I also have hypersomnia so the wakefulness effect is a nice added bonus. :) I may try a capsaicin nasal spray soon to see if it's dosage is high enough to be as effective.
Yeah I'm also concerned about it having negative effects from frequent use. It seems to help if I don't use it often, but if I use it frequently, especially multiple times per day, it seems to make me worse. I will discontinue it and research it further.
+Chuck W Yes, the achy sort of pain is transmitted by the slow, unmyelinated C fibres. This is why the pain is often not so well localized, and can only be attributed to a region of the body, rather than a specific location.
Came here when I was at Uni and you made everything make sense. Five years on I am back revising what I learnt. You are just an awesome teacher. Can I buy your series on DVD?
+Riversleigh1 You can now get all of the current videos and podcasts on a 64 Gig flash drive. About 420 video files and 100 podcasts. You can order one from campbellteaching.co.uk This saves ordering individual disks, its all on the one flashdrive. Best wishes, John
Are transducted impulses able to have any structural change in the brain region that is responsible for a specific type of pain? For example the motor cortex,does the motor cortex occur to have any structural change in the case of a chronic pain?
Does the transduction rate changes from various types of external or enviromental stimulus that are intenting to damage a particular tissue or the transduction rate is similar even if the external stimulus is huge?
Thank you, your explanations are incredibly helpful! I have a question about local anaesthetics...if they block sodium channels and hence prevent signals to the brain, why do we still have control over the movement of that part of the body? Motor signals still reach the tissue so are the sodium channels in nociceptors different to the ones in motor axons?
Dear Dr. Campbell I have a question. Isn't it the A-beta fibers that are highly myelinated and fast conduction compared to A-delta and C fibers that conduct slow pain? C-fibers are non-myelinated and A-delta fibers are lightly or poorly myelinated compared to A-beta fibers. Please let me know if I am missing something here.
Greetings! Sir I m from Pakistan! And my pain is very old about 3 years! Initially it starts from lower back pain then slightly whole back and now from 2 months I m suffering from severely high pain of spinal cord and brain ,neck .even I can't sit or do work .I can't bend or move easily.i have also checked up from Neuro surgeon Dr! But it is not improving 🥺.
Since the synapse between the Noiceceptor neuron and the spinal neuron uses glutamate as the neurotransmitter does this mean the severe pain that is constant can lead to death of the post synaptic neuron through excitotoxicity leaving a decrease ability to feel pain in the future from that area?
No, ongoing pain is more likely to lead to chronic pain, this is why it is important to prevent this chronic pain developing with use of analgesia in the acute situation.
What is the medium of the nerve fibre, the chemical makeup of the dendrite. Is this electron conduction? In both the slow fibers and the fast system. Saltatory?
+Chuck W Only the myelinated fast fibres use the saltatory form of 'bouncing' transmission. The electrical potential differences are generated by differential distribution of ions on the inside and outside of the neuronal cell membranes.
+Dr. John Campbell Knowing now that 'we' know so much detail of the nervous system and it's function is very hopeful. I need to search through all of your videos. Thank you so very much. Just knowing more of what is happening helps me to detach somewhat and consider the pain as more of a circuit than just a personal suffering. Any detachment results in reduced anxiety and reduced anxiety is a decrease in discomfort.
Oh dear God thanks for saying that about emotional reaction they are saying that my CANCER is because I have PTSD. They even say that we all were abused as a child. I think they need help in that department not me.. seriously how does cancer equate into a childhood diddled. to Cancer. I just want to give up right now.. they don't even comphrend that my head is attached to my body. As my Implant cancer has concintrated the tumor in my jaw.. area.. massive errosion.. my teeth dentene has turned soft..
1.thank you sir for your hard work. 2.why local anesthetics can't block the receptor potential at the nociceptive region but can block the action potential further along the nerve fiber ?
+LI H The local anesthetics block the sodium channels in the dendrites of the sensory neuron, therefore preventing propagation of the nociceptic neuronal impulse.
Just great. The presence and clarity of the teacher makes the information "come in and stay", more than a 3D image. Thank you for your work.
you repeat things the perfect amount of times. very helpful to absorb the info in my opinion
That's amazing Professor, indeed!!! With few details a great information!!! You have already inspired me to design better presentations!!! Thank you very much!!!
I'm studying for my modular exam on Pain right now for my undergrad degree in Psych, and these videos have been super helpful in solidifying my knowledge!
It was an absolute pleasure learning from you, thank you Doctor.
Thank you, Dr. Campbell. You have a gift of breaking down complex material to a very understandable process for the listener. In fact, I found this podcast quite enjoyable. Your speed of delivery is just right, coupled with your clear hand graphics. I will be watching your entire series on pain and pain pathways.
This is superb. Really clear. Layering on the anatomy, physiology, pharmacology, biomedical > psychosocial aspects. Thank you. Thank you. Thank you.
you are the best dr that can explain everything, you are a lifesaver, thank u
Hello professor! Here I am in Brazil learning from you. Thank you so much.
I had a meningioma in the C4 - C6 of my neck vertebrae removed in 2002. It was the size of a gulf ball but the neurosurgeon did not remove it all because it would cause severe damage to my nervous system.
The benign tumour grew again, 2013 I had surgery.
The area became infected, needed surgery again and had 6 weeks of radiation which caused the most damage.
In 4 days time, 11 February 2020, I will be having surgery again for lesions.
These video's have been more helpful than any of my GP's, neurologists', pain specialists and registered nurses.
Thank you Dr. Campbell.
❤
Wonderful - this has really helped me grasp the basics before moving on. thank you
I have become aware of a shared set of symptoms among people suffering from Spinal and Spinal cord injury, Multiple Sclerosis, Fibromyalgia, Lupus, and other disorders. The pain "matrix" is fascinating and such a worthwhile field of study for those who have a vocation for research.
You're a very clear and professional lecturer, thank you so much for these lessons.
Thank you for making this as simple and as easy to understand as possible. You are fantastic!!!
Thank you so much for the great teaching !!!
you are the idel teacher i really like the command in your voice really amazing
Thank you for this video. I live with arachnoiditis, so it's really awesome to see this video, well put together and easy for me as a pain patient to understand.
I have severe pain. :(
Excellent - these videos are really easy to understand and have helped with my degree no end. Thanks!
thank you for sharing your knowledge.All make so much sens.
Best doctor ever💕
You're a life saver
Wow. Thank you so much for helping me understand my pain.
Amazing!
you are amazing!!!
Interesting. I guess that's why snorting cayenne pepper wakes me up so well. The C-fiber to reticular pathway. I started snorting cayenne pepper to desensitize my nasal tissue to airborne irritants, but I also have hypersomnia so the wakefulness effect is a nice added bonus. :) I may try a capsaicin nasal spray soon to see if it's dosage is high enough to be as effective.
Sounds like this is working for you in the short term, but Im just wondering if there might be any longer term complications on the nasal passages?
Yeah I'm also concerned about it having negative effects from frequent use. It seems to help if I don't use it often, but if I use it frequently, especially multiple times per day, it seems to make me worse. I will discontinue it and research it further.
I guess anything that causes chronic inflammation, as frequent use would, is not good.
what an explanation.thank you sir !
Really great explanation for pain pathway
i love you doc.
Great video! Helped me a lot! A little bit too basic in the beginning, but I guess that's helpful for a lot of people :)
This is really helpful. Thankyou so much!
Woooaahhh. I just stopped this video at about 11:15. A different circuit for dull achy pain? This is a revelation. Okay, going back to watch the rest.
+Chuck W Yes, the achy sort of pain is transmitted by the slow, unmyelinated C fibres. This is why the pain is often not so well localized, and can only be attributed to a region of the body, rather than a specific location.
Excellent and easy to understand, great lecture.
There is nothing pleadureble than joy of learning. Im an engineer but learning this.
great video sir !!!!👍👌
You are amazing thank you so much why have you been all my life
great explanation。 thank you
Amazing...
Very helpful, thank you
thank you sir , finally i got a clear picture of it haha
Came here when I was at Uni and you made everything make sense. Five years on I am back revising what I learnt. You are just an awesome teacher. Can I buy your series on DVD?
+Riversleigh1 You can now get all of the current videos and podcasts on a 64 Gig flash drive. About 420 video files and 100 podcasts. You can order one from
campbellteaching.co.uk
This saves ordering individual disks, its all on the one flashdrive.
Best wishes, John
+Tim Campbell Over 400 video files? Do we earn our pHd afterrward?
Ive put all of the materials on a 64 gig USB drive now, available from campbellteaching.co.uk Thanks for watching, John
link don't work anymore
Are transducted impulses able to have any structural change in the brain region that is responsible for a specific type of pain?
For example the motor cortex,does the motor cortex occur to have any structural change in the case of a chronic pain?
thanks doc
Does the transduction rate changes from various types of external or enviromental stimulus that are intenting to damage a particular tissue or the transduction rate is similar even if the external stimulus is huge?
Thank you, your explanations are incredibly helpful! I have a question about local anaesthetics...if they block sodium channels and hence prevent signals to the brain, why do we still have control over the movement of that part of the body? Motor signals still reach the tissue so are the sodium channels in nociceptors different to the ones in motor axons?
This is a very interesting question. Did you find out why?
Excellent. Thanks
Do A-delta fibers also branch of the the reticular system as well as the limbic area ?
Good explain Prof.
You have saved my university degree!
exellent
Excellent
Thanks for sharing
I was thought that the whole long part is the axon, not just the part behind the cell body. The sensory ending are the treelike part only.
Dear Dr. Campbell I have a question. Isn't it the A-beta fibers that are highly myelinated and fast conduction compared to A-delta and C fibers that conduct slow pain? C-fibers are non-myelinated and A-delta fibers are lightly or poorly myelinated compared to A-beta fibers. Please let me know if I am missing something here.
Greetings! Sir I m from Pakistan! And my pain is very old about 3 years! Initially it starts from lower back pain then slightly whole back and now from 2 months I m suffering from severely high pain of spinal cord and brain ,neck .even I can't sit or do work .I can't bend or move easily.i have also checked up from Neuro surgeon Dr! But it is not improving 🥺.
Pleas Dr can you make vedios about Neclex
Since the synapse between the Noiceceptor neuron and the spinal neuron uses glutamate as the neurotransmitter does this mean the severe pain that is constant can lead to death of the post synaptic neuron through excitotoxicity leaving a decrease ability to feel pain in the future from that area?
No, ongoing pain is more likely to lead to chronic pain, this is why it is important to prevent this chronic pain developing with use of analgesia in the acute situation.
What is the medium of the nerve fibre, the chemical makeup of the dendrite. Is this electron conduction? In both the slow fibers and the fast system. Saltatory?
+Chuck W Only the myelinated fast fibres use the saltatory form of 'bouncing' transmission. The electrical potential differences are generated by differential distribution of ions on the inside and outside of the neuronal cell membranes.
+Dr. John Campbell Knowing now that 'we' know so much detail of the nervous system and it's function is very hopeful. I need to search through all of your videos. Thank you so very much. Just knowing more of what is happening helps me to detach somewhat and consider the pain as more of a circuit than just a personal suffering. Any detachment results in reduced anxiety and reduced anxiety is a decrease in discomfort.
Oh dear God thanks for saying that about emotional reaction they are saying that my CANCER is because I have PTSD. They even say that we all were abused as a child. I think they need help in that department not me.. seriously how does cancer equate into a childhood diddled. to Cancer. I just want to give up right now.. they don't even comphrend that my head is attached to my body. As my Implant cancer has concintrated the tumor in my jaw.. area.. massive errosion.. my teeth dentene has turned soft..
Oh Lord, calm my reticular system.
1.thank you sir for your hard work. 2.why local anesthetics can't block the receptor potential at the nociceptive region but can block the action potential further along the nerve fiber ?
+LI H The local anesthetics block the sodium channels in the dendrites of the sensory neuron, therefore preventing propagation of the nociceptic neuronal impulse.
Nice
I'd like to support you, but I really don't understand what to do with that amazon access link thing that you mention.
Go to recent videos and send payment via paypal to Dr John's Account mentioned.
SOP Class of 2018
A pHd in physiotronics?
+Chuck W O no, my research is in international medical and nursing education e.g. sgo.sagepub.com/content/5/4/2158244015612517
+Dr. John Campbell Exceptional sir.
Sir can u send the video files to us so we can show it to students. Am a doctor.
The sound of the pen marker makes me feel uneasy.why
Anthony robbins
Sometimes there is a man--I don't want to say hero, because what's a hero? But sometimes there is a man...
One typo: it should be "thalamocortical".