What is Kinesin? Ron Vale Explains
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- Опубликовано: 22 июл 2024
- Ron Vale explains the inner workings of the motor protein called kinesin (“kin-EE-sin”) that transports vital components within cells and also separates chromosomes during cell division. He discovered kinesin when he was at Woods Hole, MA and continued his kinesin research at UCSF.
I learnt about motor proteins a few years ago. Until then, I thought biology is quite boring. I think it is absolutely fascinating and also cute that something so small exists in everyone’s body. It looks incredibly cute how they walk around on their legs.
It's like they're showing off some dance moves.
theyre actually walking on their head
I'm busting balls of the Scientific Naturalists who endeavor to support Darwinian non-sense. So I insinuated that the Kinesin machines were initially only bound by 1 " foot " for millennia while awaiting the 2nd extension to miraculously incarnate.
Sorry for the confusion .... trolling's a bad habit of mine.
Your Question and your dedication for an answer is inspiring and admirable.
Keep up the great work you do! I'm very fascinated with the inner workings of the cells...
What a fantastic explanation. I took Bio-231 and we learned everything about proteins, kinesin, ATP, ADP, etc. It's fascinating to realize what goes on within our bodies.
Astonishing and actually awesome.
Still mechanistic @ the molecular level! Signature in the cell? Great book!
Thank you! I never knew this was going on.
Omg thanks ... Alot of years i wanted to know about motor protein and Kinesin protein walk animation. But not able to get correct explanation and details. Finally scientist who actually discovered this explains ❤️❤️❤️.
I wanted to be a biotechnology engineer from my school and childhood days 🥺🥺🥺🥺🥺... But now I am a software developer. But still biology fascinates me
Sizi büyüleyen şey ne ise onu yapın🎉
I hope this research rewards Dr Vale with a great life. Disciplined curiosity is what got science going in the first place. Now disciplined malevolence abuses scientific techniques to find ways to destroy or dominate others.
How do they Synchronize?
what keeps the two 'feet' of the kinesin from releasing at the same time and losing grip?
Having the one who discovered it tell about it :0
Just remarkable
Those cells be like :‘I’m walking like a model’
Ok. These are specified as base 4 digital information, as are the 6 different cargo linking proteins.
Wish Dr Vale would tell us his thoughts on how...
Was the Dynien found the same time the Kinesin was found ?
I wonder if they are run off opposing magnetic poles/fields
There are some really smart people in this world
We need stronger and smaller cameras so we may see the action closer up
incredible
Me taking getting first hand information on another level 😂🎉🎉🎉
It's so cute! 😄
what made the kinesin and the microtubules to being with ? looks way too magically complex to be random in anyway
1:35 What do you mean kinesin carrying plastic bead? 😳
This was an experiment to see if Kinesin would carry something outside it's normal routine. Lol I had the same thought though, like "uhhhh, why is plastic in someone's body??" Lol
@@Wizardmaster55 Oic.. thanks for the clarification.
Literally I paused the video to read the comments to find out if I read that right 😂 glad I'm not the only person who said "Woah, wait... What?!" about the plastic bead lmao
Pure Divine Engineering.
I have to call the ucsf billing department next week to see if I owe anything.
Awesome turning chemical energy into motion
This raises more questions than it answers.
Great job, however we still know nothing.
What do you even mean by that?
What make the kinesin move towards plus end ??
The creator our god
Energy from ATP and attraction between protein molecules
Soooooo cool
is Kinsesin the only motor protein in nerurons?
Nope. Dyenins also
Three major families
Kinesins, myosins, and dyneins can be found in neurons and in other types of cells
Could that be adapted to remove microplastic from water?
I feel like there should be a Hataraku Saibou spinoff that happens with proteins inside a human cell instead of cells inside a human body.
so instead of Cells at Work! we get the spin off Proteins at Work!
Here from, "Still Lost I Guess, Here's a Tunnel""
😀😀😀😀👍👍👍👍👍👍
here from flemming
From Twitter
I am use subtitle hindi
He hitting that Crip walk
M.I.L.M.M
Man I Love Molecular Motors
do you like monkeys?
@@stuffedcinema7374 I am addicted to monkeys. I would sacrifice my life for monkeys. I love literally everything about monkeys.
Remember all Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work. They all hopped about on 1 foot for a million years until a mutation gave them a second leg.
Do you have a source for that claim?
Ummm -- Anti Naturalistic Darwinian Biological Evolutionary Sarcasm ??!!!!!@@Cameroonian
@@WNYXeb777 Anti-Evolution? Yes. It's like saying if I jumble a few tools around long enough, I can get a Boeing Jet with instruction manual.
I prefer the tornado tearing through the Texas sized junkyard and depositing a functional ( Car, jet, hell how about a working toaster ).
Natural Science philosophy is a crock of **** . From geologic time scale and depositional sedimentation to Biology n Chemistry with Abiogenesis and Natural Selection all the through Cosmogony and cosmology everything they state is an epic failure of interpretation or a backwards manifestation of logic.@@Cameroonian ? How many Darwinists does it take to change a light bulb???? Answer --- None just wait long enough and it will change it self.
Well, that's a ridiculously frivolous claim. This guy and his team discovered the thing in 1984, but here you come along and know the history of this protein, based on what evidence? Surely not archeological evidence. Why didn't anyone describe the origin story for kinesin before they knew of its existence. We just barely understand the mechanisms of this thing, as Mr Vale said, there are lots of unanswered questions and if you don't fully know the mekanisms of a process you can't give reliable explanations for its origins. But you can always show the opposite is true and describe some other structures and mechanisms that no one knows about and along with thier origin stories.
As above so below
سبحان الله
Subhan Allah the Creator ❤ Thank you for spreading knowledge.
All of this, no matter how complex, comes down to the very same BEGINNING QUESTION.
If in deed we are too complex to be created by random chance happenings, and we were purposely created by design.
HOW was the first being or whatever in this chain of life and creators created? BUT BY THE SAME CHANCE OF RANDOM HAPPENINGS, THAT ARE SAID IT'S IMPOSSIBLE TO DO.
Or in short.
Who and How was the first "????" that was created, CREATED?
Or is that us?
Or where and who or what "was it" ?
This is and may always be the ultimate "BEGINNING QUESTION".
ENJOY
How great is our God creator
There is truly an intelligent Creator at work. God is unfathomable.
God is good.
And thay say there's no god سبحان الله
prove there is one , your ignorance of the origin does not prove anything.
There could be a god operating behind every single atom of every single kinesin, in every single cell of every single organism. But it would be stupid for us to even create a name for a designer capable of that. We should work more intensely over the minor details, and who knows... Perhaps one day we'll be able to put all the pieces together and build a god from them. The only thing that I'm sure about, is that science is the best tool we have in order to discover a god ruling the universe.
@@TIR4NO It's the same mystery of dark matter or to even comprehend that there was simply nothing before the big bang.
It's just funny avant-garde athiests and thiests battle eachother to death over such topics cyclically.
@@azertyuiop432 u repeat ur comment ?...u sound like a religious fanatic
*Jehovah : The Supreme Universal Geneticist* ♾️ 🔭🔬 glad the tiny humans are finally figuring it out, took them until 1984 to discover Kinesin. It was in operation long before that, so much more to discover!!! 😁
Evolution built these. :)
@@Communist-Doge nonsense
@@Communist-Doge yeah, doesn't prevent Him from knowing kinesin was in operation, even assuming He hadn't built it himself
قال - تعالى -: بسم الله الرحمن الرحيم ﴿ وَمِنْ آيَاتِهِ أَنْ خَلَقَكُمْ مِنْ تُرَابٍ ثُمَّ إِذَا أَنْتُمْ بَشَرٌ تَنْتَشِرُونَ ﴾ [الروم: 20].
سبحان الله !
And people actually believe that none of this is by design! That it just happened by chance and mutation. Not possible for this complexity at such a microscopic level, one single error and the entire cell is non existent and every cell after it. How does this cell mutate into a far more complicated one? Got to be a designer, a builder an architect one must conclude.
Maybe a f*kwit would conclude it. 🤣
How complex must the designer be to create such complexity, then who created the designer. It's just ends in a loop without a real answer.
Edit1: you wouldn't even know about this to comment "God did it" unless vastly more intelligent people worked on the problem and found out what's really going on.
It ends in a loop because you falsely assume infinite dimensions. Surely, there is a 4th dimension, but theres no logical reason God has to have a designer in a dimension higher than him. Or else, he isn't God. He would be just like us. It's more correct to assume God has reached the wall of all the dimensions, and there is simply nothing beyond. You might say, "well how can that be, God must have a God higher that created Him". The fact is, you assume your logic is sound, which means your mind has been formed in the ONLY correct way that accurately describes reality, which means, it must have been created from a sound mind. If not, then you can't even claim your own beliefs as accurate. You cant simultaneously be an accidental consciousness that formed from random accidents, and also, have a brain that is programmed in the only precise way that accurately perceives your reality. Your brain is either created with the ability to discern reality, or it's an accident, which hallucinates "reality" which could entirely be false, in which case you shouldnt be making any claims of intelligence whatsoever.
God's perfect design, this is evidence of a divine workmanship that is absolutely impossible by means of evolution. Psalm 139
Thank you 🙏🏽
Who created God
@@phython124 No one, if we humble ourselves and empty ourselves of human pride, we can acknowledge that there is One greater than us, whose signature is all over creation, from the intricacy of the human body to the glory of nature to the vastness of the universe.
@@maxd5298 I have no pride - don't worry about that. Yes he is above us but who or what created him?
I have no clue, therefore I believe.
Quran "We will show them Our signs in the horizons and within themselves until it becomes clear to them that it is the truth. But is it not sufficient concerning your Lord that He is, over all things, a Witness?"
Quran "Travel through the land and observe how He began creation. Then Allah will produce the final creation. Indeed Allah, over all things, is competent."
Quran "Recite in the name of your Lord who created - Created man from a clinging substance. Recite, and your Lord is the most Generous - Who taught by the pen - Taught man that which he knew not.
Bullshit
"All of these questions that one wants to know the answer to..." Seriously? The evidence of God's miraculous creation are screaming at you, but you won't listen. You have rejected the very God that created YOU, and the mind-boggling complexity found in every living being, even at the nano particle level and beyond. If you truly want to understand, repent of your rejection of Him. Admit that you were "fearfully and wonderfully made" by God; you owe your very existence to Him; you've violated His laws and commandments. Accept that He came here willingly as a human in Jesus Christ, died to pay the punishment for your sin, and rose again, overcoming death itself. He, alone, offers you eternal life. If you deny Him, He will deny you and your "after life" will be spent in perpetual torment in a very real place called Hell. Yes, you are free to choose. That means you are also free to choose life, to choose to love, follow and submit to the very one that gave you life to begin with. Ask God to forgive you, and accept Christ as your savior-this is my prayer for you today. In love and peace.
Allah Hou Akbar
Evidence for Intelligent Design.
The Lord Jesus Christ.
❤✝️🙏✝️⚓✝️
No
@@boxdemension A nano biological machine must've been intelligently designed.
Can you at least agree on that?
@@hwd71 No.
Just because we perceive similarities between biological systems and actual human-made machines is no proof that the biological systems were deliberate. It's very unscientific to assert X because it "makes sense to me"
@@boxdemension Can I convince you that the Pyramids only have the appearance of design?
That they are actually three hills that just happened by the product of random chance action of wind and erosion over millions of years to look intelligently designed but are not?
Is that a reasonable assumption?
Did anyone actually see them being built?
And after all they are made up of the same material as the surrounding rock.
@@hwd71 no. These aren't appropriate comparisons.
Again, this is very unscientific. You can't go around looking analogies and similarities between things and say "this looks complicated. It must be designed."
There are whole fields of study dedicated to finding out the origins of these complicated biomolecular systems. There are research articles proposing tentative evolutionary pathways for things like ATP synthase undergoing scrutiny and peer review.
If the creationist "proof by analogy" method is so foolproof, where are your Nobel prizes? You'd essentially be proving the existence of a God.
The number of "this is OBVIOUSLY designed" comments I see under a video showcasing a biomolecular systems seems to correlate with how analogous that system is with actual human made things.
ALLAH O AKBAR (Glory be to ALLAH)