Lec 22 Amine Synthesis

Поделиться
HTML-код
  • Опубликовано: 3 ноя 2024

Комментарии • 94

  • @bradwolfe3124
    @bradwolfe3124 3 года назад +35

    You get a sense of how much he genuinely enjoys talking about chemistry. Definitely keeps my attention. The fact that this is free to watch on RUclips is great, definitely deserves more views.

    • @Skunkhunt_42
      @Skunkhunt_42 3 года назад +2

      Id pay for it

    • @waltersobchak7275
      @waltersobchak7275 2 года назад +3

      Definitely. Fair to say I like this guy

    • @noname-80lbs
      @noname-80lbs 2 года назад

      @@Skunkhunt_42 well in fact if you wanna go deep in this info you got to pay I I'm not talking about that phenethylamines Dr his wife and their vast work in the field both chemistry and detailed biochemistry I am referring to modern research you will find PDF files on sale Dr surgin provides 2 approaches to MDMA one piperonal and isosafrol piperonal from piperine and isosafrol eugenol

    • @Skunkhunt_42
      @Skunkhunt_42 2 года назад

      @@noname-80lbs not sure what your saying. But for academic publications behind paywalls - there's scihub and libgen for that

    • @noname-80lbs
      @noname-80lbs 2 года назад +1

      @@Skunkhunt_42 RHODIUM.....THE HIVE....are good for research
      I´ll check out your info, thanks
      anyway I have more than enough papers
      I´d be making experiments for a while till needing more data

  • @DIGITALVHS
    @DIGITALVHS 4 года назад +64

    I'd love to have an orgo chem lecture where we go to erowid and talk about Alexander Shulgin's work

    • @gratefuldoge8598
      @gratefuldoge8598 Год назад +4

      I need that Rhodium / Trout sideclass

    • @DIGITALVHS
      @DIGITALVHS Год назад +7

      @@gratefuldoge8598 guest lectures from Strike

    • @triple_gem_shining
      @triple_gem_shining Год назад

      🤦‍♂️😅

    • @uraninite8151
      @uraninite8151 Год назад

      My dreams😂. Also interested in modern alternatives to the ones presented on those websites/archives. Apparently they are quite outdated?

  • @toreschanke4086
    @toreschanke4086 2 года назад +5

    Although I already know that kind of chemistry, It's greatly entertaining to see a charismatic teacher that has this kind of enthusiasm combined with knowledge and experience in this field!

  • @clovenbeast5183
    @clovenbeast5183 3 года назад +13

    I just bought PiHKAL and TiHKAL because of the references I've been seeing to so many years and they are great books

  • @togoth1
    @togoth1 2 года назад +20

    little note - methamphetamine is not present in adderal. Just standard amphetamine (L and D mix)

    • @bigboss9817
      @bigboss9817 2 года назад +3

      and thats why adderal sucks. you dont want the L type.

    • @monke3552
      @monke3552 Год назад +2

      @@bigboss9817 Its a 3-1 ratio of d and l isomers, so it's still mostly Dextroamphetamine. Besides, L is not useless, it still has activity.

    • @Kirt44
      @Kirt44 Год назад

      I know that if you want meth you make pervitin that is essentially the original meth amphetamine

    • @syzygy4365
      @syzygy4365 Год назад +2

      Thank you for this. I get so sad when people compare these two. I know amphetamine never made me want to steal from others, hallucinate, or chase someone down with a meat clever. I just like to study, work, and take care of my family. 😥

    • @Kirt44
      @Kirt44 Год назад +1

      ​@@syzygy4365 and methamphetamine will also not make u behave in this way /
      If you ever do or did these things you mention it is you and your true self that makes you do it becouse there is something wrong whit you! Stimulants can only stimulate any and every feeling or state of mind that you already are in /has in you from the start

  • @kagamer21
    @kagamer21 Год назад +2

    Your love for chemistry is so engaging! I really appreciate the energy you brought to this lecture :)

  • @triple_gem_shining
    @triple_gem_shining Год назад

    Love the enthusiasm. I hope i have teachers like you in the future. And thanks for freely uploading such great knowledge

  • @clovenbeast5183
    @clovenbeast5183 3 года назад +6

    I'll be 40 this month and I've been going to that site since I was like 18 17 maybe

  • @shepardsinsequence
    @shepardsinsequence Год назад +2

    24:32 beautifully explains how cyanide messes with the electron transporters in the mitochondria

  • @aryanprivilege9651
    @aryanprivilege9651 3 года назад +14

    Looking up organometallic rxns, I stumbled here. Like a fortunate student who finds gold like this. these are the teachers you need, those with passion about the subject.
    Can feel the interest & he $hows irl relevane! Learning & teaching can be the symbiotic reaction if both are the CATALYSTS! No matter how you got here, let the love of curiosity & chemistry take hold. Coof Please?!? Thank you sir, great teachers are the True Heroes!

  • @WuDDuP-eh7ie
    @WuDDuP-eh7ie 3 года назад +3

    Ive been looking for real in debt discussions on chemicals. Thank you so much 🕉💚✨

  • @pakman422
    @pakman422 2 года назад +2

    Forget about regular money this is GOLD🏆💰

    • @Kirt44
      @Kirt44 Год назад

      TRUE !
      This info, this knowlegde , and understanding of this is gold! you can even make it into kilos of gold if you do this reaction, then you sell the product you get from it for gold 🎉

  • @charleschidsey6192
    @charleschidsey6192 2 года назад +3

    Dr. Van Vranken,
    Thank you for “showing us the money”.

  • @chemicalaffair.
    @chemicalaffair. Год назад

    that's the kind of chemistry teacher i would have liked to have back in school!

  • @flaplaya
    @flaplaya Год назад

    You know your stuff on sub. PEA's sounds like experience no doubt. Awesome lecture I will relisten a few dozen times. Alex Shulgin is looking down from psychedelic heaven happily 😊

  • @dimascuwk1362
    @dimascuwk1362 3 года назад +2

    You are the best, thanks dad ❤️

  • @triple_gem_shining
    @triple_gem_shining Год назад

    Even though im only at the stage to take ochem 1 I understood a lot ! And i learned a lot too! Thank you!!!

  • @triple_gem_shining
    @triple_gem_shining Год назад +3

    Hamilton's gotta be lurking in these comments somewhere

  • @heroacross
    @heroacross 2 года назад +2

    I hope that I get into this university, so that I can take your courses.

    • @noname-80lbs
      @noname-80lbs 2 года назад +1

      I am afraid going to school will never be so good on the other hand you can spend two years of Laboratory practice and you won't even finish with pikcal

  • @samarmstrong6341
    @samarmstrong6341 Год назад

    Your videos are really awesome and professional

  • @everythingexplained3226
    @everythingexplained3226 7 месяцев назад

    I remember Nichols saying most phenethylamines can be reduced with Sodium borohydride and ethanol, instead of LiAlHydride an ether. Much more safe and cheap

  • @metri0n
    @metri0n Год назад +1

    Adderall is not methamphetamine... It's an amphetamine salt combo. Usually Dextroamphetamine and racemic amphetamine.

  • @yusefsadik8730
    @yusefsadik8730 2 месяца назад

    MONEY!!! hahaha, absolute awesome video sir

  • @markdunstan8277
    @markdunstan8277 Год назад

    Brilliant this is love them

  • @_macrophage
    @_macrophage Год назад +1

    I think you have "Serenity" wrong.. That looks like 3,6-dimethoxy-4methylamphetamine. DOM is 2,5 dimethoxy. Adderall is a mix of dl-amphetamine salts or pure d-amp in Dexerdrine.

  • @ppmaks668
    @ppmaks668 Год назад +3

    methylphenidate is not an ampheramine neither an amine its a completly different drug group

    • @Kirt44
      @Kirt44 Год назад

      And so what methylphenidate is relevant to the synthesis and its a farmakologic and neuro toxic similar compound , the molecule structure probably Even is close to each other,
      Analogs

  • @mrx2062
    @mrx2062 3 года назад +1

    DCC is practically not useful, because of tedious work-up. There should be more practical ways to make that amide. Better a reaction, which does not produce quantitative amounts of waste from the DCC reagent to make such a simple amine. If really DCC is needed, better use EDCI instead for easier work-up. A direct amidation may be achieved by reductive amination.

  • @bikeyogi16
    @bikeyogi16 2 года назад

    hey david! would you please provide a link for the amazing background-music

  • @SuperYTPmaster
    @SuperYTPmaster Год назад +2

    Nope. Adderall is dextro and levoamphetamine, not methamphetamine.

  • @chadwik4000
    @chadwik4000 3 года назад +1

    Does anyone remember JLF Poisonous Non-Consummables?
    I totally had forgot about EROWID!

    • @Skunkhunt_42
      @Skunkhunt_42 3 года назад +1

      I got a copy 🙂 i cherish it greatly

    • @larryjarvis8294
      @larryjarvis8294 2 года назад +1

      Sure do! What fun that was

  • @hampoop35andywhitlock49
    @hampoop35andywhitlock49 2 года назад +2

    So have you heard of kava or kratom? I’m trying to make a patch. A patch that slowly absorbs over days, instead of taking grams capped up or in powder

    • @toreschanke4086
      @toreschanke4086 2 года назад +1

      The biosynthesis of the active compounds would probably be interesting to you then.. But, I remember the challenge and fun of growing Salvia divinorum back in the 1990'.And, exploring a psychedelic plant, before it was common knowledge. Of course the way the plants made salvinorin A, and isolating the compound was very intriguing. It wasn't even like now, that everything can be looked up on the web - and even have a Wikipedia article that covers much of it. But I still wish I could grow those plants that you mention. I remember when I tried to grow as many plants with special properties as possible. I think it's a thing that I'll have to try again! (Even though I live in a challenging climate for many species).

  • @rudymelo880
    @rudymelo880 2 года назад +1

    Adderall is not methamphetamine. Its just amphetamine

  • @CmdrJameson007
    @CmdrJameson007 11 месяцев назад

    Chem 51C : Discover Mash Josh Soni Jordan Jag

  • @koenjanssen5838
    @koenjanssen5838 3 года назад

    David i tought LiAlH4 did not reduce alkenes, whatsup with that?

    • @strife3084
      @strife3084 3 года назад +1

      It doesn't reduce whats called "simple Alkenes". i.e. ethene, methane, propene etc. these are all phenyl substituted Alkenes. huge difference in reactivity.

    • @jorgejimenez4325
      @jorgejimenez4325 Год назад

      Really electrophilic alkenes (like nitroalkenes) can be reduced

  • @rendhy_8864
    @rendhy_8864 2 года назад +1

    Can you tell me the ingredients and how to make it, I really want to know. Isn't it legal for science, because I don't circulate it. please tell me, for anyone of you in the comments column who knows the ingredients and how to mix it,🙏🙏 meth and MDMA🙏🙏

    • @noname-80lbs
      @noname-80lbs 2 года назад +1

      I´m affraid it´s a little bit more complicated man.

    • @rendhy_8864
      @rendhy_8864 2 года назад

      @@bigboss9817 I'm from Indonesia, can you tell me about that?

    • @rendhy_8864
      @rendhy_8864 2 года назад

      @@noname-80lbs I'm from Indonesia, can you tell me about that?

    • @noname-80lbs
      @noname-80lbs 2 года назад

      @@rendhy_8864 I dont know much about the subject but the book the teacher mentioned. let me check out one thing

    • @rendhy_8864
      @rendhy_8864 2 года назад

      @@noname-80lbs can you help me so I can get the material guide book and how to make it, I'm from Indonesia,

  • @nilnik2673
    @nilnik2673 2 года назад

    What's the instrument in the background?

  • @chadwik4000
    @chadwik4000 3 года назад

    DOC was a real whopper it looked like, in Pihkal

  • @mubsz
    @mubsz 2 года назад

    turn up the music i can hear u

  • @polinaknoroz5523
    @polinaknoroz5523 Год назад

    Anyone noticed the Indian background music 🎵

  • @stephenjacks8196
    @stephenjacks8196 4 года назад

    She put an axe in his head but they're still in love.

    • @BushyHairedStranger
      @BushyHairedStranger 3 года назад +2

      “She put an axe in his head but they’re still in love”-Stephen Jacks
      Please explain.

    • @stephenjacks8196
      @stephenjacks8196 2 года назад

      The Shulgins had a fight. But they buried the hatchet.

    • @ericami5642
      @ericami5642 Год назад

      I think your confusing people

  • @salimsopari
    @salimsopari 2 года назад

    does anyone know how to make 2cb?

  • @jhoughjr1
    @jhoughjr1 9 месяцев назад

    Id expect a teacher to know meth and addetal are not the same thing