Phage Therapy Targeting Antibiotic-resistant Bacteria | Paul Turner | TEDxBinghamtonUniversity

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  • Опубликовано: 26 ноя 2024

Комментарии • 63

  • @mjphilip5824
    @mjphilip5824 2 года назад +35

    I'm a biomedical student student in Uganda doing some research with phages. This is very helpful

    • @mikhailrulev4886
      @mikhailrulev4886 Год назад +3

      In some cases, the use of blue iodine to combat superinfections can help. In the USSR there was a research scientist Vladimir Makhnach, who for many years studied the antibacterial properties of blue iodine. There are his scientific works! In particular , in the period from 1942 to 1955 , he helped to cure more than 1000 patients from dysentery with an iodine starch complex !

  • @ip3931
    @ip3931 2 года назад +19

    I rarely find topics I'm interested in but this Phage is definitely something I'd like find out more about.

    • @Ana-bw7gm
      @Ana-bw7gm 2 года назад

      There is lots of information on internet.

  • @innocentagaba7076
    @innocentagaba7076 2 года назад +8

    There is beauty in using biodiversity to solve huge problems. Normal things solving abnormal problems

  • @aviatornic2839
    @aviatornic2839 2 года назад +12

    This was incredibly informative, and reassuring at the same time.

  • @austinroberson8
    @austinroberson8 Год назад +16

    Superbugs aren’t coming people, they are here. It’s beautiful how Mother Nature has given us a way to combat everything that’s thrown at us, yet tragic how we try to find ways to monetize it. Especially something as important as this. The pure greed of drug companies will trump what’s right.

    • @malachiwhite2195
      @malachiwhite2195 5 месяцев назад

      What herb would kill a superbug?

    • @keenanrice2612
      @keenanrice2612 3 месяца назад

      I currently have a bacterial infection that has no oral antibiotic cure. I currently have a PIC line and have to dose 3times per day.

  • @michaelperez965
    @michaelperez965 Год назад +4

    I been obsessed with phages because of all they can do for us

  • @tcf70tyrannosapiensbonsai
    @tcf70tyrannosapiensbonsai Год назад +6

    I'm surprised, that Dr. Turner is telling us about the limitations of phage therapy, as if the whole world would have used bacteriophages generally since their recovery. He may be right about their limitations, but the research he's talking about sounds fishy like making patents for the pharma industry, while finding phages isn't profitable.

    • @johndock9164
      @johndock9164 Год назад +3

      Agreed. I think he's doing it on purpose. Phage development would reshape drug industry. Phage therapy works in Europen countries, what Americans are different humans?

  • @taylorlaster714
    @taylorlaster714 Год назад +9

    Soo... My husband was recently diagnosed with CLL leukemia... We are currently homeless, uninsured... He is terrified of dying ultimately from painful infections... I'm spending all day and night researching anything that might give him more time. These phages give me hope even though we'd have to move mountains to travel out of the USA to get treatment. If anyone has information that would be helpful to my situation, please, I need all the help I can get...

    • @anjaliv95
      @anjaliv95 Год назад

      Hey how are you

    • @jarrettthomas4865
      @jarrettthomas4865 Год назад

      Hey just checking in..have you found anything? I just heard about this stuff so sorry I can’t be more helpful 😢

    • @rayperez4825
      @rayperez4825 Год назад

      Hows it going

    • @IFrozenFireI
      @IFrozenFireI Год назад +1

      Eliava Phage Therapy or Poland

    • @fuzzyhair321
      @fuzzyhair321 Месяц назад

      It does exist in the USA. But it's still experimental treatment

  • @yogastfan
    @yogastfan 2 года назад +13

    Im glad phage therapy is still going on with reasearch

    • @Ana-bw7gm
      @Ana-bw7gm 2 года назад +3

      Doing research for the past 100 + years. Other countries are using phages to treat people.

  • @poornimam5597
    @poornimam5597 2 месяца назад

    Excellent information...But I have got a doubt....the resistance is not only developed by using proton pumps...it's also by enzyme modifications, target gene modifications, and also by gene transfer right...what about those? Like will phage therapy help solve resistance developed by those methods too?? Like are there other methods to combat that? Really curious ...if anyone knows the answer please do reply..

  • @dulynoted2427
    @dulynoted2427 2 года назад +9

    Is this the same idea as letting your children play in the dirt, being exposed to the environment, having pets and being handled by different people as a baby to diversify and strengthen their gut biome?

    • @lv1543
      @lv1543 Год назад +6

      No

    • @xana3961
      @xana3961 Год назад

      The idea is this:
      We inject the patient with a phage that attempts to kill the anti-biotic resistant bacteria. If it kills it, fantastic! If it doesn't, the bacteria had to give up one of its defenses to our anti-biotic drugs to fight off the phage, making our drugs able to kill it again. The bacteria can't have both anti-biotic defenses *and* phage defenses. It has to choose one or the other.
      The cocktail of anti-biotics and phages, then, means that we can destroy the defenses of the bacteria to our super weapons and use those super weapons (that previously didn't work) to kill the bacteria killing us.
      Think of it as if we're sending spies to sabotage the enemy defenses before we send in the missiles to *destroy* the enemy

    • @KateSmith-h2f
      @KateSmith-h2f Месяц назад

      This is why you need to listen to the talk.

  • @Sehara
    @Sehara 5 месяцев назад

    Where can I sign up for the trial?

  • @AestheticLinesUrdu
    @AestheticLinesUrdu 2 года назад

    I have done pharmD from Abbottabad University. I am interested in working on phage therapy.

  • @OriginLinear
    @OriginLinear 2 года назад +7

    What is the likelyhood that a wondering phage could lead to the evolution of a phage that kills good bacteria causing unintended consequences?

    • @Ana-bw7gm
      @Ana-bw7gm 2 года назад +9

      It didn't happen for the past few billions of years, unlikely to happen now.

    • @fallen4055
      @fallen4055 2 года назад +3

      @@Ana-bw7gm just because something didn't happen but that doesn't mean it will not...

    • @Ana-bw7gm
      @Ana-bw7gm 2 года назад +1

      @@fallen4055 Don't hold your breath.

    • @Ana-bw7gm
      @Ana-bw7gm 2 года назад +9

      @@fallen4055 Phages that kill bad bacteria will not start killing good bacteria because each of them is specific to one bacteria. When bacteria evolves and becomes resistant to phage the phage evolves as well a bit faster. I am reading a lot about bacteriophages (because I have a superbug) and didn't come across them killing good bacteria. Thinking logically there would be phages that kill good bacteria but doctors would not be giving them to patients when treating bad bacteria (and this last sentence is just my opinion).

    • @jacksheep80
      @jacksheep80 Год назад

      Well from what i know, phages are huper focused on the bacteria it consumes, some can can eat bactria from then same family of the bacteria it consumes it i heard that rare

  • @Wfb_DVM
    @Wfb_DVM 8 месяцев назад +3

    If bacteria mutates against phases, wouldn't that inevitably cause phages to mutate to bypass those factors? 🧐🤔

    • @KateSmith-h2f
      @KateSmith-h2f Месяц назад

      Yes, it would. All research points to this. Additionally, bioengineering in phages is common.

  • @Thestudents9020
    @Thestudents9020 2 года назад +8

    I am from Pakistan and working on e. coli phages i have isolated two bacteriophages

    • @Nobody-dp8br
      @Nobody-dp8br Год назад +1

      Sure….

    • @Thestudents9020
      @Thestudents9020 Год назад +3

      @@Nobody-dp8br yes

    • @mkaz3997
      @mkaz3997 Год назад +1

      And presumably you can evidence this ? If not, its just talk.

    • @Thestudents9020
      @Thestudents9020 Год назад +1

      @@mkaz3997 Not just a talk, I have evidence

    • @mkaz3997
      @mkaz3997 Год назад +1

      @@Thestudents9020 and what is your evidence?

  • @piecesofme8531
    @piecesofme8531 Год назад

    Where are the clinical trials?

    • @austinroberson8
      @austinroberson8 Год назад

      Georgia has been using Bacteriophages for over 100 years.

  • @duaneelliott5194
    @duaneelliott5194 8 месяцев назад +2

    Sounds like this guy just learned about it, and didnt realize that its been used effectively for almost a 100 years.

  • @vikkiprevette2934
    @vikkiprevette2934 11 месяцев назад

    How about focusing on minerals/ vitamins… etc…
    The food we consume blocks SO much if this… like copper kills viruses.. /bacteria..
    It’s in supplements..

    • @DerelictSong
      @DerelictSong 6 месяцев назад

      copper is also toxic to living things that is why it kills bacteria if you accumulate to much of it you will developed a heavy metal poisoning, for copper you start to produce more reactive species of oxygen that are not very good for your dna. bacteriophages only affect a small group of bacteria's at most that are very closely related so the risks for their use are pretty much non existing.