Proteolysis-targeting chimera-BOC Sciences

The Proteolysis targeting chimeras (PROTACs) utilize the intracellular ubiquitin-proteasome system for target protein degradation. A PROTAC consists of a ligand for the protein of interest, a ligand for the E3 ligase, and a suitable linker that ensures the correct orientation of and the distance between the two ligands. BOC Sciences provides high quality services and products to support drug discover in the field of targeted protein degradation.