If the alleles that code for the production of A and B antigens are still functional in an individual with Bombay phenotype but can't attach to the red blood cell because the H antigen is missing then what happens to the antigens that the blood cells produce ? Do they just float off into the bloodstream? How can people with Bombay phenotype still be a universal donor if they have free-floating A and B antigens? Wouldn't the blood donation recipient's body detect these free-floating antigens? Especially since their blood still has functioning sites to bind antigens to.
So, you are saying her dad can be a carrier of incomplete H deficiency (H/h) and still present as AB when the A & B alleles that he inherited are both dominate genes IAIB? So, I'm assuming the H he carries can still convert to A & B antigens while also carrying a gene for h?
Im not sure that I follow your final statement. Bombay could be considered a universal donor more than "O" even though bombay would have anti-H in its serum/plasma (?) - which would react with the H antigen(s) on the RBCs of the other blood groups (ABO blood group)..? Maybe Im misunderstanding your point and idea...
In donation, the plasma is separated from the red blood cells when she says Bombay blood is the complete universal donor she means that the red blood cells can be given to anyone, even though the plasma can't be
Finally a good, simple and to the point explanation of the Bombay group! Thank you so much!🥰
This was such an interesting and informative video! thank you
Thank you, EzyBzy!
Now do a video on the rare cis-AB blood type.
I have tested for Bombay blood group. My dad is AB neg,mom O pos. I have always tested out at O neg.
That's so interesting!! How did you realize you were Bombay if you have always tested as O neg? I hope you don't mind me asking haha
Great explanation!
Very helpful! Thank you!
Thank you ❤
Thank you very much ❤️❤️❤️❤️
If the alleles that code for the production of A and B antigens are still functional in an individual with Bombay phenotype but can't attach to the red blood cell because the H antigen is missing then what happens to the antigens that the blood cells produce ? Do they just float off into the bloodstream? How can people with Bombay phenotype still be a universal donor if they have free-floating A and B antigens? Wouldn't the blood donation recipient's body detect these free-floating antigens? Especially since their blood still has functioning sites to bind antigens to.
Thank you😭 youre amazing
Thank youu!
Thank u it's amazing
So, you are saying her dad can be a carrier of incomplete H deficiency (H/h) and still present as AB when the A & B alleles that he inherited are both dominate genes IAIB? So, I'm assuming the H he carries can still convert to A & B antigens while also carrying a gene for h?
The H antigen does not need to convert. It is only needed for the the phenotypic expression of either A or B antigens.
Im not sure that I follow your final statement. Bombay could be considered a universal donor more than "O" even though bombay would have anti-H in its serum/plasma (?) - which would react with the H antigen(s) on the RBCs of the other blood groups (ABO blood group)..? Maybe Im misunderstanding your point and idea...
In donation, the plasma is separated from the red blood cells when she says Bombay blood is the complete universal donor she means that the red blood cells can be given to anyone, even though the plasma can't be
Bombay red cells as universal donor
I have the Bombay B group
Wow!your name? , where are u from?