It's interesting to see this from this perspective. But what I think he's encountered with that troublesome group is that they have become "sugar burners" exclusively. It's probably a mitochondrial issue, as in damage to the mitochondria, that is not reversed simply by losing body fat or body weight. That's what it looks like from here. This is where serious exercise comes in: HIIT and weights. The resulting mitogenesis will reenable fat burning metabolism at rest. The problem is, however, the older the mitochondria, or more damage there is to mitchondrial DNA (due to refined carbohydrates and vegetable oils, for example) the less easy it is to reverse, if at all. Conclusion: the troublesome phenotype B group have possibly irreversibly damaged mitochondria. Diabetic metabolism (sugar burning) is essentially accelerated aging.
Since I'm not a real scientist, I've got a pet hypothesis that I like and want to promote. It's the relationship between body weight/size and composition and carb tolerance. I posit those of shorter stature and lighter overall body weight (examples: women, Asian populations. East African populations) can be more carb tolerant. People of larger stature (examples: men, Northern European and West African populations) tend to be less carb tolerant. I suggest a mid-point of around 70 kg (150 lbs). Once the body gets above that weight, it becomes increasingly difficult to maintain health on a high carb diet.
Have you seen the research on the Sherpa having different capacity to process carbohydrates and therefore tolerate the extreme air conditions in the Himalaya's... oxygen metaboliosm...
I've been reading books and watching presentations by Dr. Ken Berry and Dr. Jason Fung and have started increasing my dietary fat to lose weight. My wife, worried about the rate I consume butter, urged me to investigate the disadvantages of low carb - high fat diets. The first on-line criticism of the keto diet I read was by a journalist who was awarded a prize by an organization funded by Coca Cola. The next article was a pro vegan attack on animal fat which interspersed photos of abused livestock with a very specific attack on Dr. Ronald Krauss. It was such a Fox News - shout down the opposition tactic, that I correctly concluded that Dr. Krauss was worth looking into. I'm grateful this work on clarifying the complex Low Density Lipoprotein.
Great talk. However for his last hypothesis regarding reduced tissue fatty acid oxidation there's a simple answer. Most phenotype b people are also insulin resistant at best and are likely hyperinsulinemic. High chronic insulin restricts fat burning, end of story. Thus they cannot lose fat while their phenotype a compatriots do so just fine.
The day I came across Dr IGUDIA RUclips channel was the day I started living a more comfortable life again after using his herbs medication in curing my Diabetes disease
Finally, a cardiologist that knows my problem! My cardiologist wants me to do away with my lower carb, higher fat diet. I showed him Trig ranges from ~650 to 2200+ and he put me on a stain with 295 cholesterol. Finally, he gave me a fibrate later as well. When I went on Keto, my Trigs went from ~650 to over 2200 but gradually came down over 16 months to ~850. Still have weight to lose, but my body is not processing the fats as well as it should. My fasting insulin is a 2 now where it use to be in the 20's before low carb diet.. My dad and uncles also have Athrogenic Dyslipidemia.
It's interesting to see this from this perspective. But what I think he's encountered with that troublesome group is that they have become "sugar burners" exclusively. It's probably a mitochondrial issue, as in damage to the mitochondria, that is not reversed simply by losing body fat or body weight. That's what it looks like from here. This is where serious exercise comes in: HIIT and weights. The resulting mitogenesis will reenable fat burning metabolism at rest.
The problem is, however, the older the mitochondria, or more damage there is to mitchondrial DNA (due to refined carbohydrates and vegetable oils, for example) the less easy it is to reverse, if at all.
Conclusion: the troublesome phenotype B group have possibly irreversibly damaged mitochondria. Diabetic metabolism (sugar burning) is essentially accelerated aging.
Can you please produce a transcript of this talk? I would
Ike to share with my MDs. Inexpensive to do with AI-driven transcription
Since I'm not a real scientist, I've got a pet hypothesis that I like and want to promote.
It's the relationship between body weight/size and composition and carb tolerance.
I posit those of shorter stature and lighter overall body weight (examples: women, Asian populations. East African populations) can be more carb tolerant. People of larger stature (examples: men, Northern European and West African populations) tend to be less carb tolerant.
I suggest a mid-point of around 70 kg (150 lbs). Once the body gets above that weight, it becomes increasingly difficult to maintain health on a high carb diet.
Have you seen the research on the Sherpa having different capacity to process carbohydrates and therefore tolerate the extreme air conditions in the Himalaya's... oxygen metaboliosm...
Excellent Information🙂
I've been reading books and watching presentations by Dr. Ken Berry and Dr. Jason Fung and have started increasing my dietary fat to lose weight. My wife, worried about the rate I consume butter, urged me to investigate the disadvantages of low carb - high fat diets. The first on-line criticism of the keto diet I read was by a journalist who was awarded a prize by an organization funded by Coca Cola. The next article was a pro vegan attack on animal fat which interspersed photos of abused livestock with a very specific attack on Dr. Ronald Krauss. It was such a Fox News - shout down the opposition tactic, that I correctly concluded that Dr. Krauss was worth looking into. I'm grateful this work on clarifying the complex Low Density Lipoprotein.
Great talk. However for his last hypothesis regarding reduced tissue fatty acid oxidation there's a simple answer. Most phenotype b people are also insulin resistant at best and are likely hyperinsulinemic. High chronic insulin restricts fat burning, end of story. Thus they cannot lose fat while their phenotype a compatriots do so just fine.
I was thinking about the last hypothesis and it didn't seem right to me. You might be on the right track.
The day I came across Dr IGUDIA RUclips channel was the day I started living a more comfortable life again after using his herbs medication in curing my Diabetes disease
Finally, a cardiologist that knows my problem! My cardiologist wants me to do away with my lower carb, higher fat diet. I showed him Trig ranges from ~650 to 2200+ and he put me on a stain with 295 cholesterol. Finally, he gave me a fibrate later as well. When I went on Keto, my Trigs went from ~650 to over 2200 but gradually came down over 16 months to ~850. Still have weight to lose, but my body is not processing the fats as well as it should. My fasting insulin is a 2 now where it use to be in the 20's before low carb diet.. My dad and uncles also have Athrogenic Dyslipidemia.
Did you try pantethine (a form of Vitamin B5)?
Please define what carbohydrates you are referring to. Otherwise this lecture is meaningless.
🙂
🙏