If stop codons are formed within CAG repeats, due to methylation followed by spontaneous deamination of cytosines in CAG so that C is transformed into T producing TAG, then perhaps decitabine or other inhibitors of methyltransferase could slow down the onset of diseases related to CAG repeats above the capacity of DNA glycosylase to excise T and fix errors.
If stop codons are formed within CAG repeats, due to methylation followed by spontaneous deamination of cytosines in CAG so that C is transformed into T producing TAG, then perhaps decitabine or other inhibitors of methyltransferase could slow down the onset of diseases related to CAG repeats above the capacity of DNA glycosylase to excise T and fix errors.
Yes the first viewer and the first commenter.