Inventing Base Editing with Doctors Nicole Gaudelli and Alexis Komor
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- Опубликовано: 18 окт 2022
- Please note: as of 6/30/22, ARK’s clients own greater than 1% of the shares outstanding of Beam Therapeutics Inc.
On today’s episode, ARK analyst Ali Urman hosts the inventors of the adenine base editor (ABE) and the cytosine base editor (CBE) Nicole Gaudelli and Alexis Komor, respectively. Nicole is the Senior Director and Head of Gene Editing Platform Technologies at Beam Therapeutics, and Alexis is an Assistant Professor of Chemistry and Biochemistry DNA damage and repair and Genome editing at the University of California, San Diego. Alexis and Nicole worked together to develop a pair of CRISPR base editors, capable of engineering precise single-base substitutions. In today’s conversation, Alexis and Nicole discuss their discovery of base editing, what base editing is, how they grew interested in the space and what the future applications of this discovery might be!
Key Points From This Episode
- Alexis and Nicole on the discovery of base editing
- What exactly base editing is
- How Alexis and Nicole grew interested in base editing
- Alexis’ interest in directed evolution
- How CRISPR and antibiotics integrate
- What itwas like working with Dr. David Liu
- The potential disease curing applications of base editing
- Why Alexis decided to go into academia rather than corporate
- Why Nicole decided to go into industry instead of academia
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YES guyz i belive in you
Ark Invest is just different!This level of transparency and down-to-earthness allows retail investors to simply trust. Keep your essense and the good work!
These two women invented the most important protein structure in human history. I'm seriously such a fan.
This was informative. And those scientist ladies are mad cute.
I really appreciate the work you guys do but please, Segment it into chapters for videos that long. Also I’m on minute 30 right now and I really hope that at the end you’ve actually talked about investing and not just about how it is to work with David 😉
Waaaa waaaa I can’t pause a video and watch it later
@@artissimulated Haha WTF, you’re missing the Point. Idk if you’re unemployed or just don’t have anything else to do in your life but I can’t waste an hour at all. Not now neither later 🤷♂️