Do Diagnoses Matter? Reconsidering Schizophrenia

The diagnosis of schizophrenia is based on observational signs and symptoms, representing and agglutination of clinical observations based on subjective criteria. In the era of the sequenced human genome, personalized medicine, and advances in deep phenotyping, it is time to reconsider the diagnosis of schizophrenia.
This lecture was presented to CURESZ on Campus by Robert Smith, MD, PhD and Sirtaj Singh, MD on September 10, 2024.
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[@richardpeckham1013]

Great talk! Thanks. I was recently struck by the idea that in the neurology lab performing EEGs (electroencephalogram), for example, testing for seizures, shows recognizable patterns of brain waves, correlating with the brain's electrical activity. But theoretically, this regularity in human brain wave patterns suggests a mechanism by which brain regions sync in a pulse-like manner electrically, casting rhythmic brain waves with identifiable peaks, troughs, and spikes correlating with a state of (brain?) mind. In a philosophical domain, the pulses support the illusion of a seamless sense of self in the world, self-awareness, and the projections of consciousness in humans. What could go wrong? Psychiatric diagnoses provide a useful construct for research and treatment of human illness and suffering. What the study of genetics and epigenetics can teach us about impacts on health and illness is amazing. Mining large data sets for useable, relevant, reliable information is an exciting frontier.