Extrinsic Pathway of Apoptosis | FAS Ligand Mediated
HTML-код
- Опубликовано: 16 окт 2024
- In this video the second pathway for extrinsic apoptosis have been discussed. This pathway is mediated via FAS Ligand and FAS Receptor.
The fas receptor (First apoptosis signal) - (also known as Apo-1 or CD95) is a transmembrane protein of the TNF family which binds the Fas ligand (FasL). The interaction between Fas and FasL results in the formation of the death-inducing signaling complex (DISC), which contains the FADD, caspase-8 and caspase-10. In some types of cells (type I), processed caspase-8 directly activates other members of the caspase family, and triggers the execution of apoptosis of the cell. In other types of cells (type II), the Fas-DISC starts a feedback loop that spirals into increasing release of proapoptotic factors from mitochondria and the amplified activation of caspase-8.
My heart is literally jumping for joy watching how organized, color coded, and structured this video is. I love it. It makes me so happy. Thank you.
Thanks Priya for appreciation.....It really boosts my confidence when i get to hear these kind of words....
Keep supporting 😊😊
i dont know how to thank you for such a nice video
as always "short , informative , high yield"
Thanks buddy for your love and support........I am really glad to know that it helps......
A fantastic, clear and concise introduction to this topic - thank you!!
I am really overwhelmed after seeing your complete video on apoptosis, I am currently doing my masters in pharmacology and toxicology, no one could make the concepts so clear as you explained in this short video. Now I really want this question to be there in my exam. I really thank you for the wonderful video, you made it really really easy. Your efforts could be seen.
thanks Dhatrika for appreciation..Glad it helps...
Correction: CAD stands for Caspase Activated DNAse.
Awesome tutorial by the way.
ANY REFERENCE BOOK ?
Your videos are so awesome with all those colorful diagrams, it makes all those topics more easier and makes us eager to understand those. Thank you so much Sir❤️❤️💖
keep Working hard and smart....May ALLAH bless you for this kind of short informative video.
Thanks Ishfaq for appreciation
U make the things so easy with the flow charts... Thanks alot!
you have ceased my caspase cascade, and I will now survive...
in 4 minut video he teach us the whole concept that greats sir g
I appreciate it. You saved my assignment score.
thanks for appreciation 😊
Thank you for sharing and good explanation.☘️
thanks for appreciation..Glad it helps ✌️
It would really really help if you could include your sources in the description. Thank you for this video though. Amazingly explained.
okay i will consider
You are such a legend.. Thank you soo much!
thanks for appreciation
✌️✌️✌️
you made my day! thank you for this amazing video
thanks for appreciation..Glad it helps ✌️❤️
You’re just doing it perfectly 👍🏻
The LEGEND✅
You are The Greatest 😊
Thanks Jelena for appreciation..... Really Glad to know that it helps..😊😊😊
very nice explaination....
stay blessed 👍👍👍
Just one little thing, I think the ligand and receptors are of 3 units (not 4) according to several sources, because they are involved in a step called trimerization. Other than that, it was a very nice video!! :D
Yeah they are 3 units , the picture depicted here is only to show the interaction otherwise it should have been trimeric structure ....Thanks for taking this into consideration
Still a very good video, thank you!@@hussainbiology
Thanks....Keep sharing and supporting
Thank you! Studying Biomedical science at university is tough!
thanks for appreciation
That was beautiful... Thank you so much!!!😊😊😊
Thanks Sanjith for appreciation....... It really makes me happy....
thank you so much, jazaakallah, your picture is amazin!
thanks for appreciation....Glad to know that it helps
Jazakallah khair! This is very helpful!
Glad to know that it helps ✌️..Keep sharing and supporting..Allah bless u
Thanks a lot !!! So simplified ❤️
thanks for appreciation.. Glad it helps
Finally!!! IVE BEEN SEARCHING THE WHOLE INTERNET AND THEY USES 10-15mins to explain this. I love this. Short n nice!:)
Thanks Alice for appreciation...... Glad to know that it helps.....
And i always try to keep my videos short and precise.
Thank you so much sir!
you are welcome
Thank you for your videos! :)
Thanks......Always here to help.....
thank u so much for this vdo...god bless
Nice explanation 🌷
thanks for appreciation.. Glad it helps ✌️
Great Video !
Very nice video
Kamal kr gaey ho sir je❣
Thank you so much !! Amazing work !
thanks for appreciation..glad to know that it helps
Ek No.
👌
Awesome 👌
Thank you
You're welcome
Thank you so much sir
You are welcome...
i’m doing a master in cancer biology and your videos are life savior!! i literally passed my cell signaling exam with 18/20 thanks to them. 🙏🏻🙏🏻🤍🤍
that is so great... Glad to know that my stuff helps... Thanks
HELP ME WITH THE REFFERENCE BOOK.YOU ARE THE BEST
thanks for appreciation..Glad to know that it helps ✌️
@@hussainbiology NO REFFERENCE BOOK?
@@LaloboJDavid Lodish Molecular Biology ( Chapter 21 ) Eight Edition
@@hussainbiology MAY ALLAH BLESS YOU IMMEASURABLY.
@@LaloboJDavid Allah bless u too my brother.
Well explained ☺️
Thanks Nafis for appreciation..Glad to know that it helps.
Supbbb explanations
thanks for appreciation..
Muito bom! 😍
Thanks for appreciation.....
Muito bom means??
@@hussainbiology It means *Very Good* in Portuguese
@@xrcc202 Glad to know that
Very nice
Thanks for appreciation....
Impressive
Thanks Fatima,,,Really appreciate ur support
THANKS
Most welcome...
Hello, somebody can tell me what is the different between MHC I and FasR?
Ya That's a good question
Tq
Thank you !!!!!!
#Medschooldiscussion
Thanks for appreciation....
this is tough to remember than TNF
But u will remember it...✌️✌️✌️
Can't understand single thing you are saying