It's Exciting! It's Excitation-Contraction Coupling!
HTML-код
- Опубликовано: 21 июл 2024
- How does a motor neuron communicate with a skeletal muscle cell? What is the connection between muscle cell depolarization and subsequent contraction? What the heck is calcium doing? And while we're at it, can we review that sliding filament theory? You bet!
Videos mentioned:
The Action Potential: • The Action Potential
Equilibrium Potentials and Driving Force: • Equilibrium Potentials...
Ligands and Receptors - The Magical World of Signal Transduction: • Basic Signal Transduct...
FREE TEXTBOOKS!!! AMAZING!!! Go get you some!
OpenStax College: openstaxcollege.org/
OpenStax Anatomy & Physiology textbook: openstaxcollege.org/textbooks/...
Want more?
Subscribe: / thepenguinprof
FB Page: / thepenguinprof
Twitter: / penguinprof
Web: www.penguinprof.com/
SPONSORED BY AUDIBLE.COM
PenguinProf LOVES Audible and now the feeling is mutual! Audible.com is the premier provider of digital audiobooks. Audible has over 150,000 titles to choose from in every genre. Audible titles play on iPhone, Kindle, Android and more than 500 devices for listening anytime, anywhere. Click to learn more and download a FREE audiobook of your choice! www.audibletrial.com/PenguinProf
Thank you for sounding so happy and excited, it really makes a difference in the learning experience. It makes learning these difficult details so much more pleasant. Thank you for cheering up science nerds everywhere :)
+Leslie Miller Thank you for appreciating that - it's subtle, but SO important! Science IS fun and wonderful! I love my profession and my students, so I'm so glad to hear it comes across. :)
Amazing!!! Grad student, you explained in 10 mins what takes most profs hours. Thank you so much for posting. I love your format.
Your clarity and optimism is greatly appreciated.
Thank you sooooo much. The animation and dialog were exactly what I needed to get my head around this concept! Your videos are great!
Your voice is so sweet I could be hearing you all day, uh, and very clear explained.
Med school professors could not explain this easy concept and you did it in ten minutes. Great researcher does not mean great teacher. Learned that the hard way.
Wow! I had completely misunderstood the entire thing when my professor explained it, but now I get it. Thanks a lot!
Thank you so much !! I couldn't find a video or textbook explaining the sequence in chronological order - thank you :)
WOOOOOW!!, this is beautiful!!. I have been reading this in my text book, my lecturer`s slides and my tutor`s notes but it made no sense!, I just couldn`t distinguish between excitation-contraction coupling, sliding filament theory and cross bridge cycling but now I get it, all thanks to you Prof!!, your work is much appreciated!.
I am SOOO glad you found this helpful! Thanks for letting me know!
Love your channel. Really helpful and easy to understand. Keep up your great work, I and many others really appreciate it!
Thanks a TON! You explained so perfect and simple. I have never understood it better than now!
Thanks for the heads up on Open Stax.... I was able to get a couple of useful textbooks...thankss :)
I'M SO HAPPY I FOUND YOUR CHANNEL
You don't know How much thankful I am to you
LOVE THIS EXPLANATION - YOU ARE GREAT - PLEASE KEEP CREATING CONTENT MEDICAL STUDENTS NEED YOU!
OK I WILL - THANK YOU FOR WATCHING!!! Good luck in med school!!!
you are an amazing professor, I love your tone of voice but what I love the most is how well you explained this. I wish my professor loved to teach as much as you do!! My respects for you ma'am.
Wow, thank you! Thanks for watching!!!
Really great video, thanks! Made this physiology chapter super easy.
THANKS SO MUCH YOU'VE LITERALLY SAVED MY LIFE!
This video helped me out so much! I'm in a one month physiology course and it's so hard to learn all of the material before an exam in 4 days. One question - does this also happen in cardiac muscle cells?
short sweet and to the point. very helpful keep them coming!
Thank you. this is very clear to me, especially your easy words and sentences make it easy to understand.
Glad to hear that!
This is the best physiology video I've ever seen...
finally someone explain the mechanism of DHP simply and professionally :)
very thankful to your exciting video, it is really informative. It provides more knowledges about DHP receptor and RyR that in my textbook doesn't exist, hope you can release more such interesting video.
So happy to hear that!
That was very interesting. I appreciate understanding whats going on at the molecule level with muscle contractions. It adds to the mind muscle connection when weight training.
Wonderful lecture hope that there are more professors like you,keep up the good work.
Thank you so much! Thanks for watching!
This was amazing! Thank you so much!
I love this channel!! Keep it up!
Great drawing! Thank you!
thank you so much. this was the most helpful explanation.
always coudn't imagine DHPR and RyR .....made it a bit clear...thanks.......please keep making more heplful videos like this....
You make it sound so easy , i marvel your way of explaining thank you
You are welcome! So glad you find my videos helpful!
very nice explanation!!!! thanks a lot
what an amazing explanation!
this is amazing, thank you penguin prof!
Thank you soo much for your helpful explanation!!!
Glad it was helpful!
I think it is important to note that there is a graded/local potential started by the nicotinic-AchR by Na influx. This in turn, propagates to activate V-gated Na channels that make a new AP. The new AP travels down the T-tuble etc.
Thank uuuuu so much you are seriously a life saverrrr!!!
Finally i understand the mechanism. Thanks !!!
I'm so glad to hear it! You are most welcome!!!
Adipoli mole ushaar ayikunnu 👍👍👍
So helpful. Thank you so much.
I love your work!
Thank you, you helped me a lot!!
Excellent explanation ! 👌👌
Thank you 🙂
The best explanation better than my professor
Thank you so much!
This was super helpful
I'm so glad!
Loved it!
This video is very awesome. However, I do have a question about the dihydropyridine receptor. Currently, have researchers been able to better understand the DHP-R (a voltage-gated L-type calcium channel) and know that it opens the ryanodine receptor by releasing calcium into the cytoplasm which binds to the RyR to open it and release calcium within the sarcoplasmic reticulum? I'm trying to piece everything together between RUclips videos and my textbook.
thank you. your video is awesome
I love you thank you sooo much!!!
thank you so much!
Great video 💕
thanks !!! really helpful
Thank you, now I understand how excitation-coupling works.
You're welcome! Thanks for watching!
ThePenguinProf I shared with my class!
I am watching this vedio in 2022 😊 I don't know fluent english but this vedio make me feel good 🤗
I'm so glad to hear it! Best of luck to you!
What a great teacher! Could you possibly tell me what a STAC3 defect affects the Ca+ and the muscle contraction?
I've read recently that STAC3 has been identified as a (possible) fourth essential EC coupling protein and it may couple CaV1.1 with RyR1 for calcium release in skeletal muscle. This would explain observed myopathies in patients with STAC3 defects. Some good info here: www.pnas.org/content/114/2/E228
thank you!!!
Thank you thank you thank you thank you thank you!!!
please do for cardiac muscle...
thank u so much! u saved me!
Hello I was wondering if STAC3 could make its way onto this video. This was great!
What os STAC 3
WhT is STAC 3
A skeletal muscle specific protein that is crucial for DHPR/RyR coupling
wow amazing! thank you so much! much better then my prof aha
Extra Thank for the link
What happens when nicotine binds to those receptors ? It does not cause muscle contraction ?
very helpful thanks thanks thanks
amazing really
thx
Thank you!
You're welcome!
No skipping ad😁 Love the of fairy penguin 😁😁
Fairy penguins ALWAYS.
wow. just wow. i can learn how to build a rocket ship with this professor.
Beautiful ❤️
Thank you! 😊
So how is the excitation-contraction coupling related to the sliding filament theory?
So sweet voice!
Fantastic
Thank you so much 😀
Good. Thank you
You are welcome!!!
woòooooow ...... very helpful. .... hundreds thanks
+Manal Kanouaa You are so welcome! Thanks for watching!
dis shit helpful dawg
You have such a lovely voice
I'll let my vocal couch know you said so! Thanks!
@@Penguinprof I meant voice modulation 😀
it's good🤗
Only worthwhile video on excitation-contraction coupling on RUclips.
how muscles grow???
Thanku mammmmmmm
You are soooooo welcome!!!
Wooooow
SOOOOO glad you like it...
❤
❤️🐧❤️
I love you
Awww... thanks!!!
Da best
Too FAST Too MUCH ....from a pro who has studied this stuff for a long long time
Thank you so much!