Mechanisms and secrets of Alzheimer's disease: exploring the brain

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  • Опубликовано: 10 окт 2013
  • A scientific film with a 3D modeling made on the inner mechanisms of the brain implicated in the development of Alzheimer's disease. Available in English, German, French and Dutch produced by Internationale Stichting Alzheimer Onderzoek (ISAO) (NL), Alzheimer Forschung Initiative e.V. (AFI) (D) and La Ligue Européenne Contre la Maladie d'Alzheimer (LECMA) (FR). www.alzheimer-research.eu.

Комментарии • 342

  • @TheCornbeefsoup
    @TheCornbeefsoup 9 лет назад +273

    Beautiful animation. I wish more biological videos were made like this.

    • @ghettrsc8764
      @ghettrsc8764 4 года назад +1

      TheCornbeefsoup exactly

    • @iloffys7798
      @iloffys7798 4 года назад

      The voice and the animations are just perfect

    • @nikkiwillis1122
      @nikkiwillis1122 3 года назад

      *Our Mom Alzheimer's and dementia story:* *ruclips.net/video/ABoP57zTFCg/видео.html*

    • @savankate7239
      @savankate7239 3 года назад

      . When I see this post I remember Dr. Osemuahu. He really made me believe in him so much. by healing me months ago with his herbal treatment from Alzheimer disease. I really appreciate you very much and he is able to cure you from any sickness and he also cured my cousin from Ischemic heart disease thanks to him ...if you have any diseases let me know so I can link you up with him ..

    • @3joewj
      @3joewj 3 года назад

      Insulin degrading enzyme is what clears the plaques but if you have too much insulin...that enzyme is sufficient only in degrading insulin and allows the plaques to build. So increasing insulin sensitivity would be the goal...freeing the enzyme to complete its other functions.

  • @1021memo
    @1021memo 8 лет назад +99

    I have never in my life seen a medical video that is good as yours, truly professional.

  • @me55n
    @me55n 8 лет назад +75

    The best medical video I've ever seen ....

  • @lostn65
    @lostn65 5 лет назад +3

    my dad died of the disease. Please cure it so no one else and their families has to go through that suffering.

    • @terriusthomas1146
      @terriusthomas1146 4 года назад

      Over 100 drug trials for alzheimers have failed! So at this point alzheimers is basically untreatable and incurable, it's really sad

    • @davidornelas195
      @davidornelas195 3 года назад

      My father died from this disease as well... So, I know how you feel!

  • @keishahouston1943
    @keishahouston1943 3 года назад +6

    Yess try do our best to make it into a understanable way our ways in Scenice so everyone can enjoy to

  • @najlaa6308
    @najlaa6308 8 лет назад +12

    A beautiful animation to summarise what's happening in Alzheimer..

  • @CMDR_John_Crichton
    @CMDR_John_Crichton 8 лет назад +6

    My granddad is currently in the later stages of this. I've come to accept it as inevitable, but its still hard, partially because I never fully understood it at the neurological level. Thank you for uploading this.

  • @ElijahPlaysTennis
    @ElijahPlaysTennis 8 лет назад +8

    For patients and caregivers, this is the most insightful and well-accessible video I've watched about the pathological bases of dementia. There is now increasing evidence that tau is present at sub-detection thresholds before amyloid though. Hopefully with the development of in vivo tau imaging markers in the next couple of years, we will all get a better grasp of the temporal sequence.

  • @user-by2tw3yg7i
    @user-by2tw3yg7i 5 лет назад +7

    When I wanna introduce Alzheimer's disease to my friends or other people, I recommend them come to this video. It's a wonderful material suitable for all people even they aren't researchers in this field.

  • @SMGAPR8
    @SMGAPR8 Месяц назад

    This is the one time that I embrace technology, a deeper understanding, very educational and a compassion for the mysteries of human mind, body and soul, superb 🙏

  • @kvvful
    @kvvful 9 лет назад +13

    real great animation and explanation even an alzheimer patient could understand

  • @polysom6345
    @polysom6345 4 года назад +1

    I freaking swear they need to make videos like this for A&P, diseases, and medication effects. I would pay good $$$ for these!!!! Videos like this are the only way I can truly understand the process of things!!!

  • @IMN602
    @IMN602 3 года назад +3

    This is the scariest thing i have ever seen...

  • @SuperIndigo2011
    @SuperIndigo2011 9 лет назад +4

    Simple and clear explanation of the disease, thanks!

  • @rebeccatemi9909
    @rebeccatemi9909 9 лет назад +13

    Very good video summarizing the neuropathogenesis of AD, however, I think it's essential to highlight the hyperphosphorylation of tau proteins

    • @ng8giga
      @ng8giga 5 лет назад

      can you explain what you mean in simple terms?

  • @zenzaiL4D
    @zenzaiL4D 9 лет назад +1

    By far the best presentation of AD I have seen. The way you integrated the beautiful music with the animation, together with the narrative made it beautiful to watch. Thank you.

  • @dr.salmanriaz1468
    @dr.salmanriaz1468 9 лет назад +4

    What a clip? Completely flawless... Awesome.. Awesome awesome and thousands of awesome

  • @yodaydyxz1752
    @yodaydyxz1752 9 лет назад

    Also this is the best animation for AD on YT.Don't even waste your time trying to look for more.
    Thanks for sharing LECMA.

  • @kaelynnsu3286
    @kaelynnsu3286 4 года назад +1

    I've read from a few articles that amyloid beta plaques activates an enzyme called kinase and kinase has a phosphate group on itself. The kinase then phosphorylates the Tau protein and that is why Tau protein detaches itself from the microtubule.

  • @255jayjay
    @255jayjay 5 лет назад

    The best medical video I've ever came across.

  • @saahilvij3416
    @saahilvij3416 9 лет назад +6

    Amazing video depicting the pathological process, very insightful

  • @Theseniorlist
    @Theseniorlist 9 лет назад +1

    Thank you for a wonderful synopsis of this most debilitating disease!

  • @coline9179
    @coline9179 8 лет назад

    so far the BEST animation of pathophysiology Ive seen here on youtube!Thumbs up!:)

  • @santoshkhotlande7213
    @santoshkhotlande7213 9 лет назад

    The Best & Simple Explanation Ever.... Thank You

  • @likemoreal
    @likemoreal 9 лет назад

    This film is very beautiful and easy to know key points of Alzheimer's disease. Thank you!

  • @carmenmperezperez1983
    @carmenmperezperez1983 8 лет назад +6

    Excellent!! Easyto follow and to understand.

  • @Isteshhad
    @Isteshhad 7 лет назад

    Such a beautiful video that actually made me emotional. Thank you

  • @medacademy3918
    @medacademy3918 9 лет назад +1

    Thanks a lot, this is the best video I found about this topic.

  • @tcdsvuzjyh123456789
    @tcdsvuzjyh123456789 9 лет назад +4

    Thank you so much for the beautiful animation

  • @jonBrazilian
    @jonBrazilian 10 лет назад +7

    Very good and well explained! gosh, how animations help us understand such a complex phenomenon like that one.. thanks for sharing! :)

  • @heastner
    @heastner 2 года назад

    Scary, yet great presentation.

  • @2000Betelgeuse
    @2000Betelgeuse 9 лет назад +30

    Great video, it makes it easy to understand

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you liked this video, you may also want to know that it's estimated that 45 million out of the 328 million people in the U.S. will have Alzheimers! That's 13.7%!!

  • @mashaelalansary3229
    @mashaelalansary3229 4 года назад +1

    Excellent video. Perfect animation and the music is so soothing. The person narrating is awesome!

  • @Nyny.1000
    @Nyny.1000 10 лет назад

    Brilliant way to tie together other alzheimers videos here on RUclips.

  • @S.Sarajlic
    @S.Sarajlic 8 лет назад +1

    Thank you! This video made me understand better about AD and it is going to help me to write my thesis! Greetings from Northern Italy.

  • @naqiyahmulachelah5668
    @naqiyahmulachelah5668 7 лет назад

    amazing, i would never understand or even interesting to "peek out" about alzheimer if i never watched this. thank you

  • @SimonePutzolu
    @SimonePutzolu 4 года назад +1

    simply amazing video !!

  • @correahanna
    @correahanna 8 лет назад +4

    so good and simple understood, with importants informations, thank you

  • @VasculexAO
    @VasculexAO 8 лет назад +2

    This is an excellent explanation of how the brain changes occur and Alzheimer's disease I would urge you to watch it several times because it has many many features that are important to understand as far as the details of how the disease happens. One addition that I would like to add is that most of these changes are actually initiated by the autoimmune process in the brain.

    • @scottwilly86
      @scottwilly86 8 лет назад

      +Raif Tawakol Inflammatory risk factors seem to promote a number of degenerative conditions. The mutation of the APP gene to those genetically predisposed to Alzheimer's occurs on chromosome 21. The majority of Down's Syndrome occurs because of that extra chromosome on 21. Down's is also up to 5 times more likely to develop Alzheimer's and/or die from other inflammatory responses/autoimmune issues in the body.

  • @mennasmaowaad3348
    @mennasmaowaad3348 4 года назад

    Thanks for the working staff, the most beautiful animation I have ever watched 💓💓

  • @SantoshKumar-tr8gj
    @SantoshKumar-tr8gj 3 года назад

    Excellent demonstration n animation

  • @angeldavidmolina9338
    @angeldavidmolina9338 5 лет назад +2

    Excelente video muy claro y conciso, además súper bien explicado.

  • @BBCeiz1993
    @BBCeiz1993 8 лет назад

    Thanks for this video today I hope to continue for other disease by this way of explanation

  • @borshanodi5077
    @borshanodi5077 6 лет назад

    Thanks

  • @mithunraaguld6999
    @mithunraaguld6999 4 года назад +1

    I am school student and you made my mind just blow you are great with your explanation

  • @drmohsingani6954
    @drmohsingani6954 9 лет назад

    Thank You! for such a great video...

  • @119alias
    @119alias 5 лет назад

    Amazing video with sad facts. Thank you.

  • @missanorajjohnthattil8526
    @missanorajjohnthattil8526 8 лет назад

    awesome work on details on both content and graphical explanation

  • @doctorsstudy
    @doctorsstudy 5 лет назад

    best video... no words to explain how much i like

  • @MattLenaghan
    @MattLenaghan 9 лет назад +1

    What an excellent video - as informative as it is artistically composed. Thank you.

  • @mikaelsilva2346
    @mikaelsilva2346 5 лет назад +5

    Que vídeo espetacular ❤️❤️❤️

  • @pranitarai615
    @pranitarai615 5 лет назад

    Amazing animated videos... This is the best video that I have ever seen..

  • @mohammedsadekon
    @mohammedsadekon 8 лет назад +2

    elegant animation, thanq guyz

  • @xinting_study
    @xinting_study 3 года назад

    Thanks for making this video, it's really informative and good-quality.

  • @TTerminatorr
    @TTerminatorr 9 лет назад +4

    Great video indeed, complexity explained in such simplicity that it gives us a great baseline to build on...
    Thanks heaps.

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you found this informative, you might want to know that Dr. Dale Bredesen at Duke University has done a lot of research in Alzheimer’s Disease and looking at possible root causes!

  • @pallavipandey.
    @pallavipandey. 6 лет назад

    Beautiful animation.and superb explanation

  • @sarat.5496
    @sarat.5496 9 лет назад +2

    Este vídeo es fantástico

  • @masanamuthu3121
    @masanamuthu3121 5 лет назад

    wht a awesome animation which includes emotional background sounds.........Which tends people to attract more towards ''Psychiatry'''

  • @axelblazefrost2213
    @axelblazefrost2213 7 лет назад

    I find it really helpful ! Thanks !

  • @TechnicalGuru-pu2ol
    @TechnicalGuru-pu2ol 4 года назад +2

    This 6 min video lecture slove my all doughts quickly so thank u so much 😊👌👍👌😊👌👌😊😊😊

  • @binbinky78
    @binbinky78 4 года назад +1

    this video is a jewel

  • @Nat.0992
    @Nat.0992 9 лет назад +1

    Oh my god! Thank you for this! I was sitting in patho yesterday and I swear I heard crickets! This helps to clear it up so much! Thank you!

  • @ankitasamaddar3318
    @ankitasamaddar3318 8 лет назад +3

    Very Useful animation and the descriptions are also very helpful..

  • @valarmathisubramaniam8635
    @valarmathisubramaniam8635 9 лет назад

    Excellent visual explanation. Thank to the advancement of Animation

  • @Lifeholder
    @Lifeholder 7 лет назад

    This is fantastic. So glad I watched it.

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you enjoyed this video, you may also be interested in looking for possible root causes behind Alzheimer's! For this, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!

  • @lauradigigli7037
    @lauradigigli7037 5 лет назад

    Thank you. Exellent video. Let's hope in sience and resercers❤

  • @mushtaqnajar8930
    @mushtaqnajar8930 6 лет назад

    Soo beautifully ...love it totally

  • @fayju
    @fayju 10 лет назад +2

    a very helpful and positive video.

  • @kryptoniite_
    @kryptoniite_ 8 лет назад +2

    Amazing.

  • @santhinatarajansanthinatar9380
    @santhinatarajansanthinatar9380 5 лет назад

    How Awesomatic animation is! Superb

  • @Tura750
    @Tura750 7 лет назад

    This video is amazing. Thank you so much!

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you're interested in looking for possible root causes behind Alzheimer's, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!

  • @divimsdd93
    @divimsdd93 5 лет назад

    Wat a video😍.... Chanceless.... Best visual ever👌👌👌

  • @monoromerovl
    @monoromerovl 10 лет назад +1

    Technology is a beautiful thing!!

  • @studentxcmu
    @studentxcmu 6 лет назад

    Thanks for uploading this video. I am a student. It helps me a lot.

  • @cherryice103
    @cherryice103 8 лет назад +2

    Great explanation thank you so much

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you're interested in research that looks at possible root causes for Alzheimer's, check out the work of Dr. Dale Bredesen. He had a 2018 study in the Journal of Alzheimers Disease & Parkinsonism. The study is titled: "Reversal of Cognitive Decline: 100 patients." It's fascinating stuff!

  • @krisanthonysilveira8244
    @krisanthonysilveira8244 8 лет назад +1

    great great great video ..
    The graphics ..

  • @Farzaneh72
    @Farzaneh72 8 лет назад

    you caused I understand clearly... thanks... good job and keep going...

  • @bellahilal
    @bellahilal 6 лет назад +2

    Great animation. It is like that i wish.

  • @Ash-bb1vp
    @Ash-bb1vp 4 года назад

    Beautiful ..

  • @srilakshmidondapati1564
    @srilakshmidondapati1564 3 года назад

    Superb video for medical students 👌👌

  • @nikhilnagpure4679
    @nikhilnagpure4679 6 лет назад +1

    Awesome ...thanx maam

  • @tasneemfahoum5931
    @tasneemfahoum5931 5 лет назад

    magnificent animation! great job on raising awareness of Alzheimer's !!!!! hope that scientists find a cure for this disease!

    • @nikkiwillis1122
      @nikkiwillis1122 3 года назад

      *Our Mom Alzheimer's and dementia story:* *ruclips.net/video/ABoP57zTFCg/видео.html*

  • @malavikapradeep9771
    @malavikapradeep9771 4 года назад +2

    Very informative video. Thank you so much.

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you liked this video, you may also want to know that it's estimated that 45 million out of the 328 million people in the U.S. will have Alzheimers! That's 13.7%!!

  • @aliciaflores5052
    @aliciaflores5052 9 лет назад +1

    This was a great video. It was very educational and the animation was very detailed.

  • @saraar5794
    @saraar5794 6 лет назад +1

    You are creative ,,, very informative 💜

  • @PhuongNguyen-ks6rq
    @PhuongNguyen-ks6rq 8 лет назад

    this is an amazing video !!!!!

  • @idealcomputer2198
    @idealcomputer2198 6 лет назад

    beautiful

  • @frenchmtv
    @frenchmtv 9 лет назад +7

    Very informative, and I enjoyed the music as well. Would like to know the artist.

  • @vipashapmehta
    @vipashapmehta 7 лет назад

    amazingggg graphics....superb explanation...👍

  • @shafayetullah1021
    @shafayetullah1021 3 года назад

    Excellent

  • @chocolatebar1592
    @chocolatebar1592 4 года назад

    My Grandma has Lewy body dementia. This video made me feel really sad,as she were quite bad today

  • @sysneco
    @sysneco 9 лет назад

    It's a great educational material.

  • @kartikasari5603
    @kartikasari5603 5 лет назад

    good explanation and nice video

  • @nooral-rawi4447
    @nooral-rawi4447 8 лет назад

    Very beautiful

  • @mranonymous8224
    @mranonymous8224 5 лет назад

    Best I have ever seen

  • @TheSebasPower
    @TheSebasPower 10 лет назад +1

    Great work! thanks for uploading this :)

    • @OswaldDigestiveClinic
      @OswaldDigestiveClinic 2 года назад

      If you're interested in looking for possible root causes behind Alzheimer's, look at the work of Dr. Dale Bredesen at Duke University! He looks at possible causes like: pathogens/gut infections, intestinal permeability of the gut (leaky gut), microbiome imbalances, insulin resistance, nutrient deficiencies, hormone imbalances, and toxin exposures!

  • @Mah5663
    @Mah5663 6 лет назад

    Very attractive video

  • @professionalnurses9641
    @professionalnurses9641 4 года назад +1

    "Awesome Explanation" :-)

  • @Gerry363c
    @Gerry363c 3 года назад +2

    My father died of this. He was 63. I have witnessed every stages of it to his very last breath. Worst experience ever

    • @gracelady3092
      @gracelady3092 2 года назад

      I have be dealing with Alzheimer's disease for the past years until i got review online about Dr Favour on RUclips Channel people testifies how they got cured with his herbal medicine, I order the treatment and after taking it for few weeks i totally got cured

    • @gracelady3092
      @gracelady3092 2 года назад

      Whatspp him for help

    • @gracelady3092
      @gracelady3092 2 года назад

      ±14157878148⏯️⏯️⏯?????????

  • @Usemefortrending2024
    @Usemefortrending2024 2 месяца назад +1

    amazing and thank you!