Pediatric Hematology Board Review

This video explain the blood disorders in the Pediatric Board Study Guide; A Last Minute Review
*RBCs disorders
Anemia
Erythrocytosis
*White cell disorders
Neutropenia
*Platelet disorders
Thrombocytopenia
Abnormal platelets
*Coagulation disorders

[@taral1000]

One of the best pediatric presentations, all videos are must listen. Really appreciate your efforts sir

[@pediatricboardalastminuter1892]

Thanks a ton

[@goldenfish1059]

44:30 clinical approach to a patient presents with microcytic Anemia
47:14 Macrocytic Anemia
54:47 approach to a patient with Macrocytic anemia
58:46 Normocytic Anemia
1:51:33 platelet disorders
2:03:27 Coagulation disorders

[@pediatricboardalastminuter1892]

Thank you for comment. What is the question?.

[@goldenfish1059]

@@pediatricboardalastminuter1892
I don't have a question. I just wanted to reach these parts easily. Thanks a lot

[@olufunmilayoelizabeth9487]

🎉🎉 u the😅

[@drabuhanafi6039]

بارك الله فيك و نفع بك و بعلمك و متعك بالصحة و العافية

[@MrSaadnice]

يعطيك العافيه يادكتور محاظرة قيمة ومفيدة

[@dr_mohamed_salah]

شكرا جزيلا استاذنا الكبير
محاضرة ماتعة ملخصه و افيه
اسأل الله العظيم ان يبارك في دينك و علمك و عملك و اهلك و مالك

[@pediatricboardalastminuter1892]

Glad you liked it! Thank you!

[@ahmedhamad5534]

استفدت كثيييييرا ،جزاكم الله خير الجزاء علي الشرح الممتع

[@mohsinfareed1797]

Great as usual.Thanks very much for the wonderful lecture. Thanks for the great great effort to help others. God bless you. بارك الله فيك

[@pediatricboardalastminuter1892]

You are very welcome. Thanks.

[@BabarKhan-qp6nq]

So concise and at the same time not even a single detail is missing . beautiful ly explained .thanku sir .

[@pediatricboardalastminuter1892]

Most welcome 😊

[@MrCookieberry]

THANK YOU FOR YOUR LECTURES! CLEAR, STRUCTURED AND GREAT TO LISTEN...EXCELLENT FOR PEOPLE WHO STRUGGLE TO READ TEXTBOOKS

[@pediatricboardalastminuter1892]

You are very welcome! Thank you very much.

[@sherifbatawy]

good job جزاك الله خيرا

[@albouq0081]

الله يجزاك بالجنة وينفع بك الامة يدكتر
تحياتي لك من المدينة المنورة

[@pediatricboardalastminuter1892]

Thank you very much, That's very nice of you to say.

[@salwahelmyelshafei6403]

Thank you doctor Osama for your very excellent and structured videos. It is a very big effort really, God bless you
really you are great.

[@pediatricboardalastminuter1892]

You're very welcome! Thank you.

[@goldenfish1059]

thanks a lot Dr. Osama. may Allah grant you Paradise.

[@pediatricboardalastminuter1892]

You are most welcome

[@irfanashraf3697]

It is best comprehensive lecture thank you 😊

[@drshjan]

بارك الله فيك و نفع بجهدك الرائع د اسامه , متابعينك و ربي يجعلها صدقة جارية لك باذن الله , استمر و ربي ييسر لك امورك كلها , ياليت تتوفر نسخ من كتابك بالسعودية

[@pediatricboardalastminuter1892]

+Shjan Hassan Thank you very much for the nice comment, Jazakom Allah Khiran. Here is the link on Springer website for Saudi Arabia. www.springer.com/gp/book/9783319101149?countryChanged=true

[@pediatricboardalastminuter1892]

+PEDIATRIC BOARD A LAST MINUTE REVIEW Also Amazon is another option. www.amazon.com/Pediatric-Board-Study-Guide-Minute/dp/3319101145/ref=tmm_pap_title_0?_encoding=UTF8&qid=&sr=

[@user-ko4gq6jp2y]

بارك الله بكم اخي الحكيم اسلوب رائع

[@pediatricboardalastminuter1892]

Thank you!

[@dhaiheart6917]

oh wow ,you made it simple .... thank you
جزاك الله خيرا :)

[@pediatricboardalastminuter1892]

Thanks

[@farisalshboul998]

Thanks very much , I felt chills at the end of this wonderful lecture , you are a great role model to follow and respect , much love for your soul
Again thank you for your time in education
الله يحفظك حكيم

[@pediatricboardalastminuter1892]

Thank you very much.

[@HafizahHoshni]

Simply excellent. Very grateful for clear, concise and well presented video. Thank you for the great channel. 13/8/2018 😊

[@pediatricboardalastminuter1892]

Thank you!

[@aidash6111]

Thank you very much. May Allah reward you abundantly

[@pediatricboardalastminuter1892]

You are very welcome. Thanks.

[@ajmalnazir2120]

Well elaborated lectures in detail of all types anaemia
Thanks sir jee

[@pediatricboardalastminuter1892]

Most welcome

[@mahaahmad7267]

I’m speechless,thank yo so much❤️❤️❤️❤️❤️❤️

[@pediatricboardalastminuter1892]

You're most welcome! Glad you like it. Thanks

[@rababerriany9208]

U r great doctor , thanks a lot ,, please we need lecture for rheumatological diseases doc

[@pediatricboardalastminuter1892]

Thanks. I will do as soon as I can.

[@yasirmohammedali]

Thank you very much for this great achievement.
HbH is it detectable by electrophoresis ? Why then it has a specific name ?

[@TanveerAhmad-wg3xx]

JazakAllah

[@dharmaraogera3333]

Very useful and helpful information. If possible can you please share more information in dealing the sickle cell anemia.

[@pediatricboardalastminuter1892]

+Dharma Rao emedicine.medscape.com/article/205926-overviewThank you very much, click on the above link for more information about SCA.

[@ASh-zl8yv]

Thanks in advance for your huge effort

[@pediatricboardalastminuter1892]

Thank you!

[@ackatharzan9386]

you made whole pedia Simple for me :) Thankz sir

[@pediatricboardalastminuter1892]

Thanks

[@ackatharzan9386]

:) :)

[@basheeroudahus3747]

thanks alot. Really great way of teaching. Please make more videos ;-)

[@pediatricboardalastminuter1892]

Thanks

[@user-ne9zp4yt2u]

عفوا دكتور
ليش ب الفا ثلاسيميا
Neonate electrophoresis find hemoglobin bart
But after that normal

[@roshanakthar8480]

Assalamualaikam.... great videos sir ... upload more sir .. will remember you in my duas...

[@pediatricboardalastminuter1892]

Thanks

[@zekrabulbul7916]

شكرا دكتور الله يجزيك الخير

[@jaafarmohammedjawadal-jaza208]

Thanks a lot for these wonderful videos.
Just in sickle cell disease, you mentioned that glutamine becomes valine, but many references mention (glutamate or glutamic acid) becomes valine ?

[@pediatricboardalastminuter1892]

Yes!! you're correct, its glutamic acid, will correct it in the updated videos. Thanks.

[@jaafarmohammedjawadal-jaza208]

PEDIATRIC BOARD A LAST MINUTE REVIEW with my pleasure

[@user-xq7dm2fp5n]

You are great sir , still amazing

[@mngames514]

Ww thank u amazing concept and simply exp

[@pediatricboardalastminuter1892]

Thank you!

[@noraalghoul7955]

شكرا كثيرا جدا على هذة المحاضرات الرائعه. ..شرح رائع وشامل..بس لى رجاء مافيش محاضرات فى neonatology .....
لو فى امكانيه ياريت .....ونكون شاكرين لفضل حضرتك.....

[@pediatricboardalastminuter1892]

+nora alghoul Will do my best to cover all the chapters in the Pediatric Board Study Guide including the Neonatology section. Thank you for your nice comment

[@ghaith2431]

Jazakallah DR,

[@pediatricboardalastminuter1892]

Thanks.

[@medomokh2877]

thank you...

[@samighosson771]

At 29:46 It is better to write (Hgb Barts) instead of (HgB BARTS)..... At 1:29:50 Is it right to say (vascular) necrosis instead of (Avascular) necrosis ? At 1:37:54 (Heinz bodies seen in unstained red blood cells) but in your explanation you said (will require a special stain...)

[@akhtersmrcpchhelpline980]

MasAllah.JajkAllahu khair

[@pediatricboardalastminuter1892]

Thank you!

[@Roqya22]

Kindly make more videos....love your explanation

[@pediatricboardalastminuter1892]

Thank you, I will

[@mariyameskienyar2115]

Thank you!!

[@pediatricboardalastminuter1892]

You are very welcome!

[@ghazwan58]

Thanks Dr Osama for excellent videos. Is TIBC stands for Transferrin or Total Iron Binding Capacity?

[@pediatricboardalastminuter1892]

Total iron-binding capacity (TIBC) or sometimes transferrin iron-binding capacity is a medical laboratory test that measures the blood's capacity to bind iron with transferrin. Does not stand for TIBC.. its an indirect measurement of transferrin protein which an iron carrier protein....If the iron is low and the liver is healthy, the liver will be signaled to produce more transferrin to look for any circulating iron to carry it, in the case the carrying capacity of transferrin is high and saturation is low...saturation is low means more transferrin protein is available but less available iron to carry.. Thank you

[@umteebakereem7543]

lots of thanks

[@pediatricboardalastminuter1892]

You are very welcome

[@parthasarathidas7279]

Awesome .. thanks a lot sir :)

[@pediatricboardalastminuter1892]

Thanks

[@darbazsoran493]

Well Done Doctor

[@pediatricboardalastminuter1892]

Thank you

[@samahpedia514]

Good after noon Dr Osama, would please explain how to differentiate between mild and intermedia Thalassemia using the numbers of electrophoresis ? A2 F and A1
Thank you

[@pediatricboardalastminuter1892]

Electrophoresis result showed: Hb A > 98% with a small amount of Hb A2 visible --->Normal electrophoresis
Electrophoresis of a 3-year-old child, the result showed: Hb A is decreased to 94%, Hb A2 is increased at 5%, and Hb F is 1%--->Beta thalassemia minor
After birth, hemoglobin electrophoresis result showed: No Hb A, Hb A2 of 4%, Hb F of 96%. No other abnormal hemoglobins seen
--> Beta thalassemia major
Intermedia is tricky. In-between both Minor and Major require a specialist to make this diagnosis.

[@samahpedia514]

Thank you very much

[@babariqbal413]

​@@pediatricboardalastminuter1892❤

[@samsam-tf5ph]

Thank you so mush

[@pediatricboardalastminuter1892]

+sam sam You are very welcome!

[@yasirmohammedali]

Hello dr. Osama... Thank you

[@pediatricboardalastminuter1892]

You are welcome

[@ayda.mohammed]

The best 👌

[@hamdahiftikhar1716]

How can you give oral iron to infants I am confused..am I interpreting it wrong

[@sanjayakupadhyaya6001]

THANK YOU

[@pediatricboardalastminuter1892]

+sanjaya upadhyaya You are very welcome!

[@mustafamajidh7940]

Thank you, doctor,
I'm am a 6th-year med student from Iraq.
Could I use the same diagnostic plan for internal medicine anemia diagnosis?
I hope you could answer,
Best regards.

[@pediatricboardalastminuter1892]

Not sure about adult medicine.

[@mustafamajidh7940]

@@pediatricboardalastminuter1892 OK.
Thank you doctor.

[@ibrahimelhabbak6411]

Marvelous

[@pediatricboardalastminuter1892]

Thanks.

[@natalyghanem5662]

Thank you

[@pediatricboardalastminuter1892]

+nataly Ghanem You are very welcome!

[@bahaaashwirf1968]

Alot of thanks

[@pediatricboardalastminuter1892]

Thank you!

[@redanofal4501]

السلام عليكم ورحمة الله وبركاته. بارك الله في علمك يادكتور
why alpha thalassemia show normal electrophoretic pattern???? thanks.

[@pediatricboardalastminuter1892]

Alpha Thalassemia: Newborn screen shows
hemoglobin Barts (g-tetramers
produced only in infancy)
Electrophoresis outside of infancy is
normal
Beta Thalassemia:
Newborn screen normal
Electrophoresis shows ↑ hemoglobin
A2, ↑ hemoglobin F
(electrophoresis should be
interpreted in the setting of
normal iron stores)

[@muhammadharis2967]

Asalamualaikum
Sir hope you are in the best of your health,i have 1 question,in your book you mentioned about blood transfusion which is 5ml/kg but here in pakistan we transfuse about 10 to 20 ml per kg,
1 other question please sir can you describe the whole milk,you states that dont give whole milk below 12months,thank you sir

[@pediatricboardalastminuter1892]

It is not easy to digest whole milk in infants younger than 12 months, plus may cause constipation, and iron deficiency.

[@medomokh2877]

I would like to know how can I differentiate between extra and intra vascular hemolysis in Lab???

[@medomokh2877]

Example you mentioned is already intravascular hemolysis....
So how you say ( G6PD can be associated with intravascular hemolysis) ?

[@pediatricboardalastminuter1892]

You are absolutely right, my comment was wrong about G6PD, G6PD is a predominant intravascular hemolysis type: I made the corrections here.
Decreased haptoglobin levels, hematuria, and presence of urinary hemosiderin indicate severe intravascular hemolysis.
Suggestive initial labs for any hemolytic anemia: Complete blood cell count (CBC) and reticulocyte count, Lactate dehydrogenase (LDH) level Indirect and direct bilirubin level, Serum haptoglobin level, Urinalysis for hematuria, Urinary hemosiderin, Peripheral blood smear, Then order further labs to confirm your diagnosis afterward depending on the most likely cause. Very important to know presence of intravascular hemolysis does not rule out presence of concurrent extravascular hemolysis. We can not use theses labs to confirm diagnosis, they are just suggestive, e.g. G6PD can be associated with Extravascular hemolysis, this means you have to depend on history ( e.g. family history), physical exam (e.g. splenomegaly), peripheral smear e.g. Heinz bodies, or spherocytes, e.g. to confirm the diagnosis of G6PD with quantitative assay of GPD activity. etc. to make it also more clear; Haptolobin is considered acute phase reactant like CRP, means if you have severe intravascular hemolysis because of infection, in this case you may see Haptoglobin elevated NOT decreased or absent

[@ahmedmohamed-rl3jq]

THANKS SIR

[@pediatricboardalastminuter1892]

Thanks

[@user-nw5xm9ik1n]

excellant

[@pediatricboardalastminuter1892]

Thanks

[@hilwacadey7532]

Thank you sir

[@pediatricboardalastminuter1892]

Thank you.

[@dryousafmujahid969]

Sir why there are so many lectures on hematology, i confused, some lectures are one hour and some 2 hours ,

[@medomokh2877]

G6pd can be associated with intravascular hemolysis???
it is already intravascular hemolysis...

[@pediatricboardalastminuter1892]

Thanks, I made the correction below.

[@artaeskandari8233]

Very good

[@artaeskandari8233]

Excuse me ,I want to red HUS but I don't know which one of lecturers to search ,do you help me?

[@ramyhamdy9563]

it is only 360
pleez upload with HD

[@medomokh2877]

what is sickle thalasemia??
I hear about it but don't understand it.

[@pediatricboardalastminuter1892]

rarediseases.info.nih.gov/diseases/10333/hemoglobin-sicklebeta-thalassemia

[@medomokh2877]

you mention that haptoglobin decrease in intravascular hemolysis in order to differ between intra and extra hemolysis.
but in spherocytosis you say in lab there decreased haptoglobin ??how that??
thanks.

[@pediatricboardalastminuter1892]

You are right, I did not discuss this point in details, actually there is no absolute intravascular hemolysis and extravascular hemolysis, like in cases of spherocytosis; abnormal shape RBCs, or G6PD abnormal inclusion bodies (Heinz bodies) these are classic examples of extravascular hemolysis but can be associated with mild intravascular hemolysis as well, in this case the spleen is very large, this is classic because is mainly extravscular, but can be associated mild decrease in haptoglobin, but in cases of anemia with predominant intravascular hemolysis such as paroxysmal nocturnal hemoglobinuria,.the haptoglobin will be decreased or even absent, both; elevation of LDH, plus the jaundice of course. The best way to describe these types; Causes of normochromic normocytic anemia with predominant intravascular or predominant extravascular hemolysis. In future I will try to make it more clear. Thank you very much for pointing out this difference.

[@medomokh2877]

Thank you ...

[@user-ko4gq6jp2y]

الله يرضى عليك ويوفقك ياحلى حكيم بالدنيا. ممكن فيس بوك صفحتك الشخصية عسى نستفيد من منشوراتك القيمة اخي الكريم

[@hithamabaki9625]

god bless you

[@pediatricboardalastminuter1892]

Thanks.

[@medomokh2877]

Why in alpha thalassemia Hb electrophoresis positive only in neonatal period and normal later on ??and the problem still present?

[@pediatricboardalastminuter1892]

In the newborn period, if the electrophoresis shows Hb Bart's or HbH, the infant has alpha thalassemia. The hemoglobin electrophoresis is usually normal in adults with alpha thalassemia trait

[@medomokh2877]

PEDIATRIC BOARD A LAST MINUTE REVIEW
Why normal in adult ?although alpha chain still abnormal?

[@medomokh2877]

thanks

[@pediatricboardalastminuter1892]

You are very welcome !

[@mahinurrahman1334]

love u man

[@pediatricboardalastminuter1892]

Thank you!

[@pentayyakopi4044]

👍👍👍👍👍👍👍👍

[@dalmar199]

i need your slides bro

[@emanelbadrawy9780]

بارك اللة فيك دكتورى العزيز...ارغب في الحصول علي لينك مشاهدة جميع محاضراتك استاذى...

[@pediatricboardalastminuter1892]

ruclips.net/channel/UCFO_CjLDvWxmAexhDDXC53Qvideos

[@pediatricboardalastminuter1892]

Thanks.

[@azbood]

👍

[@a.d5550]

Anemia of chronic disease 15:15

[@1mwithnovideos289]

Where's aplastic anemiaaa ????

[@guuldon8091]

allah yubarik fiik

[@pediatricboardalastminuter1892]

Thank you!

[@nour_said9860]

WBC 1:47

[@nour_said9860]

Plt disorders 1:51

[@DrMansouR123]

أود لو تكرمتم رقم حضرتك للتواصل على برنامج واتس آب