SIFT | Mutation Prediction & Verification Tool | Lecture 9 Part 7 By Dr. Muhammad Naveed

[@mahnoor4499]

Best lecture series of bioinformatics on RUclips.. Thanku sir💐

[@Prof.Dr.MuhammadNaveed]

Pleasures and welcome dear

[@tahiraaslam4365]

Best professor ever🥰Keep it up my bestest teacher..my inspiration❣️

[@Prof.Dr.MuhammadNaveed]

pleasures

[@nidajahangir8700]

@@Prof.Dr.MuhammadNaveed sir kindly guide me . from where we select mutation ?

[@Prof.Dr.MuhammadNaveed]

@@nidajahangir8700 from your sequences and then by ds SNP

[@hirasaleem8135]

Asalam o alaikum sir, which algorithm is used by sift tool ? Please reply me

[@Prof.Dr.MuhammadNaveed]

It is based on decision tree algorithm

[@shugalmela4808]

Sir nsSNPs py MS thesis mai ks type ki questioning hoskti h?

[@zohazeeshan5903]

How we can use sift n polyphen 2 on SNPNEXUS ?

[@Prof.Dr.MuhammadNaveed]

sift, polyphen 2 and snpnexus are different. each tool has its own uniqueness

[@mishalhassnain5865]

Sir plz make video on protein PTM

[@Prof.Dr.MuhammadNaveed]

sure

[@learnbiologyy]

Respected sir how can we check the effect of mutations found in 3'UTR region

[@Prof.Dr.MuhammadNaveed]

do docking or Gene ontology

[@nadyaanggraini8489]

hello, thanks for your explanation.
I want to ask you, I have a vcf file (415 mb) and sift 4g annotator running > 1,5 hours, is it normal?

[@Prof.Dr.MuhammadNaveed]

Not possible

[@Cryptology4U]

How missense mutation causes disease?

[@Prof.Dr.MuhammadNaveed]

It render the resulting protein nonfunctional, and such mutations are responsible for human diseases such as Epidermolysis bullosa and sickle-cell disease

[@Cryptology4U]

@@Prof.Dr.MuhammadNaveed Thank you so much

[@saya2587]

There's a lot of stuff in this software I'll take what final fake information it take to put it in my work table according to this software

[@Prof.Dr.MuhammadNaveed]

you just put mutation properties in result and left rest