FREE RADICAL MEDIATED CELL INJURY

A series of video tutorials discussing the pathology of cell injury and adaptations.
In this tutorial , i have discussed PATHOGENESIS of free radical mediated Cell injury
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FREE RADICAL MEDIATED
CELL INJURY
• These are the chemical species/ atoms or group of atoms that have single or more unpaired electrons in their outer orbit.
• Highly reactive, unstable chemicals
Conditions where free radicals are implicated in cell injury and death
• Injury due to chemicals/drugs
• Ischemia reperfusion injury
• Irradiation
• Phagocytosis leading to killing of microbes
• Cellular aging
• Carcinogenesis
Free radicals
• Superoxide oxygen
• Peroxide (Hydrogen peroxide)
• Hydroxyl radical
• Nitric oxide
• Peroxynitrite
• Hypochlorous acid
Antioxidant mechanisms
Enzymatic Antioxidants
• Catalase
• Superoxide dismutase
• Glutathione peroxidase
Non-enzymatic Antioxidants
• Endogenous or exogenous substances which inactivate free radicals
• Vitamins A, C , E
• Sulphydryl containing compounds
• Cysteine and glutathione
• Serum proteins
• Ceruloplasmin and transferrin
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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
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[@giannaking2224]

My textbook was awful at explaining this. Thank you so much for taking the time to make this video!

[@shridharmahishiQoW59Zo]

Your coaching is very lucid; lots of subject matters ! Thanking you

[@felistuskafwala2703]

I will continue watching your videos because it's encourage me on how to understand pathology bit by bit

[@sanjaybharati154]

sir,u are doing a great job..kindly upload videos on remaining chapters ..

[@drp2761]

Sir plz make lecture on special path
I really like the way u teach its simple easy to understand plz help in special pathology plz

[@sukhneetkaur2132]

Thank you so much sir❤

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Pathology is More about anatomy and biochemistry

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