APOPTOSIS PART 1: Definition, Causes & Mechanism/Pathways

A series of video tutorials discussing the topics for undergraduates in Pathology
In this 1st part of Apoptosis tutorial , i have discussed Definition, Causes & Mechanism/Pathways
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• Definition of apoptosis
• Causes /conditions where apoptosis is seen
• Understand the mechanism of apoptosis
• Extrinsic pathway
• Intrinsic pathway
A pathway of cell death
Induced
By a tightly regulated suicide program
Found in 1972 John Kerr, Andrew H. Wyllie & Alastair Currie
Greek - mean "falling off" (like leaves falling from a tree)
Also referred to as programmed cell death
PHYSIOLOGICAL CONDITIONS
Embryogenesis
Involution of hormone dependent tissues
Menstruation, menopause, weaning
Loss of cells in proliferating cell populations
Bone marrow, thymus
Removal of self reactive lymphocytes
Death of inflammatory cells after their functions are over
PATHOLOGICAL CONDITIONS
Injured cells which cant be repaired
• DNA damage
• Misfolded protein accumulation
• Viral infections
• Duct obstructions
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Please watch: "WARBURG EFFECT: Hallmark of CANCER. What, Why & How?"
• NEOPLASIA 6: WARBURG E...
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[@xT..]

I'm currently preparing for my Professional exams(400 lvl MB) for pathology and pharmacology, i'm going through your videos again as a part of my study material. You are the best, Thank you so much Sir..

[@hritvikjain__3594]

I generally don’t comment of the educational videos on YT. But if I’m commenting, the shit is really awesome. I was so scared of Apoptosis, that i even decided to skip it for my exams. But after watching this video, the mechanism of apoptosis is very clear to me now.
Thank you sir 🙏🏻.

[@ilovepathologyVijayPatho]

Hritvik Jain thanks 😊 glad you liked it 😊

[@Kyle0714]

I wish you taught pathology at my school. I had no idea that Caspase was a mashup of 3 different things, crazy!

[@TheSK1199]

Thank you sir. Reading robbins is so easy after watching your video

[@92soofiyanoushad8]

Sir, this vedio is really an exam capsule 😍.thank you

[@saidattarachamani1373]

Ur Lectures are tooooo good sir .thank u so much sir.

[@selvambigaig6541]

Awesome. Keep up the great work. A real boon for students.

[@17anandp86]

Such a wonderful class
So easy to grasp the topic after hearing your class sir

[@pakapapita3104]

Thank you so much sir, I read Robbins only after watching your videos.

[@Artsylove4]

Me too

[@doc599]

Ahhh.....such a detailed yet precised explanation

[@kapilnath4059]

Precise Explanation sir . Thank you very much ..

[@josetrujillo738]

I enjoy your lectures. I appreciate your very great ability to teach

[@criticaltruth5184]

awesome videos. love the details of the caspaces and the IAP family

[@samyu7925]

please make more videos like these sir🙏🙏🙏

[@ananyagupta9730]

Thank you so much. I have much better understanding

[@Artsylove4]

Thank you so so much sir for this tutorial ..❣️

[@50divyaramesh77]

Excellent video which explains each and every point clearly😊please do more videos in all topics as possible.

[@rianacaeiro8711]

Very well explained, thankyou so much.

[@benazirnowshath9002]

Could anyone give explanation more than this for apoptosis?! Really awesome sir🙌

[@DrDmitrii]

Thank you brother!

[@narendrachaudhary609]

Wow..love it❣️
Such a good explanation in short time

[@lpangmeiphom1324]

Cleared my basic concept 🤘tq sir

[@anushabachchu1273]

Simple and super sir!

[@Baharaakbari]

Amazing thank u so much ☺️

[@shameenabanu1143]

Thank u so much sir .....it is so. Much clear explanation
....

[@harshaharidas4786]

Thankuu very muchh sir
Very helpful👍👍

[@vaisshnavi1257]

Smooth like butter 🧈🤌🫶💥💕💜💜💜💜💜💜💜💜

[@ilovepathologyVijayPatho]

Thank you 😊

[@arvaoz6799]

Was very helpful! Thank you so much! :)

[@pubsmedworld101]

Best teacher for pathology

[@ilovepathologyVijayPatho]

Thank you 😊

[@venkateshwarlugangishetty8853]

Wowww,simply super 👏👏

[@HassanAli-zq3ml]

simple and clear

[@tahiransari3917]

Very helpful sir

[@TheSandeepkumar1991]

Thanks you sir..

[@ikramshehzad6936]

Thanks 😊 sir which one book you following?? For better understanding of pathology

[@doc599]

Robbins pathology

[@koolshakthi1985]

This is excellent. Thank you!

[@anaskp4667]

Love your classes

[@janakignanan7793]

Thanks a lot :) This helped me alot for my degree :)

[@piyumidissanayake6244]

great sir,thank you

[@sindynurafia4063]

im coming from country who dont use english as daily basis, so its difficult for me to listen and understanding something in english . you should turn on the subtitle, it would make me easier to understand. at least i can read it.

[@destiny6955]

Skill issue

[@nandinimoorthy3163]

super great job

[@abhijityeole8462]

Awesome. Thank you soo much sir!

[@zainabalradi2306]

you are a god

[@phoolphool396]

Really helpful video

[@puneetsharma1134]

thankew sir.

[@abhi-wi2mj]

Explanation was very nice.

[@ilovepathologyVijayPatho]

Glad you liked it

[@JoohiTalks]

Thank u sir for this lecture

[@suman-by7gt]

thanks so much

[@chagalamukamorris4744]

Chagalamuka used this ❤

[@jaydeepchauhan7712]

sir this is the fantastic explanation, sir...can you please make a telegram channel for multiple choice questions practice,so that we can apply the knowledge of pathology

[@ilovepathologyVijayPatho]

Thanks so much :-) I think there is already a telegram channel for MCQs practice.. you can join that

[@jaydeepchauhan7712]

@@ilovepathologyVijayPatho can you mention the name ....plzz sir

[@ilovepathologyVijayPatho]

jaydeep chauhan "pathology UG Quiz😊"

[@shashishah7887]

could you please elaborate how the molecules on inner side of cell membrane got to be on the outside?because that's what caused phagocytosis...

[@SMM-qp9ig]

Gorgeous way

[@nagamanigv8225]

Thank you sir nyc teach

[@13.tarunchandwani51]

Thank you sir

[@21aparnamadhusoodanan94]

Thankyou sir❤️

[@JackT13]

I like the video but I thought apoptosomes were heptamers (7 sub-units)?

[@rutujamohite4890]

A Great Thank you

[@Daawonuurka]

Thank you From Somalia 🤒🥲

[@fatahabdinur5383]

saved my life

[@polokocollen7072]

Thank you.

[@rikkigupta9546]

Thanks alot sir

[@ilovepathologyVijayPatho]

Most welcome

[@rosejasmine4214]

Very useful👍👍👍 thank you

[@内田寛-d7x]

H7

[@sainiksefteri7832]

how apoptotic factors are occurred and where? Due to WHAT?

[@fatahabdinur5383]

ty bro

[@sabreenmodak7746]

Can i please know the name of the book that you've referred here?

[@sebastianm.6875]

amazing

[@Rohit-fy4kl]

Sir which book you are following

[@saloniparekh8419]

This is so simple and easy to understand.R u from india?

[@ilovepathologyVijayPatho]

sanjana parekh thanks 😊 and Yes!

[@hibakaleed387]

Please can I get this file I need to study it ?

[@laurachueire4625]

perfect

[@غصنالزيتون-ط4ب]

❤❤❤

[@pavanjadhav5116]

Thank you sir....still I hate patho😭

[@ilovepathologyVijayPatho]

Wish I could make it interesting for you 😊

[@anaskp4667]

Could you please share the ppt

[@tejasgadekar6153]

👍

[@anaskp4667]

Sir

[@ursgp7]

❤

[@imanehdjb402]

S'il vous plaît, quelqu'un me traduit les causes de l'apoptose en français

[@nativetexan6628]

I'm sure your video is very good, but I couldn't understand the words you were saying. I got a few words but your accent is so heavy that I just couldn't get it. I am so sorry.

[@pheonixheart5534]

💜💜💜🏌️‍♀️

[@kidzstories2412]

Thank you sir easiest slide & explanations to follow 🙏🙏🙏

[@padmamahindravada]

Excellent video. very clear. Thank you sir

[@ilovepathologyVijayPatho]

Glad it was helpful!

[@MohamedHashimMohamed-w8h]

thank U 👍

[@shahnasshajahan529]

Thank you 💟😊

[@shitalsurushe7496]

Thank you

[@ourvinesshahzad3931]

Thank you sir

[@abhi-wi2mj]

Thank you.

[@ilovepathologyVijayPatho]

You're welcome!