Small mistake: Usually hydrogen is just a proton (no neutrons), but deuterium (1 proton and 1 neutron) and tritium (1 proton and 2 neutrons) also exist. I believe there was a mix up between mass number and number of neutrons
Thanks for pointing that out. You're totally right and I don't know how that simple mistake made it past my editing. The conclusion of the Klinman experiment still stands: heavier isotopes react much more slowly than expected, so they must take advantage of tunneling. Thanks again for the correction!
Thanks a bunch friend!! I think i'm finally setting into a style I like and can replicate. I'm happy to get back to the more macro anatomy and phys though, this quantum stuff is well past my comfort zone
Medlife Crisis well I’m stoked to know that aspectish is officially a verb haha. But yeah it’s awesome to see Pat’s style (and skills!) developing and I loved this look and feel for this episode!
What little I know about enzymes reminds me of my childhood. My mom once told me meat was so difficult to chew because my saliva lacked the enzymes to break it down into a swallowable form. I later found out it was because everything was cooked well done and tough as nails.
I mean she’s not wrong. I’m pretty sure only your stomach and intestines are able to produce enzymes that break down proteins (they’re called peptidases) Saliva contains mostly amylase (sugar breaking enzymes) and lipases (fat breaking enzymes)
I am also here from Up and Atom. Very happy that you took up the topic of quantum biology. I am a biologist, also interested in physics. I read the quantum biology book by al-Khalili & McFadden last year and became completely fascinated. Hope the discussion will continue. I like Up and Atom and have seen many episodes there, so now I found this channel and have subscribed.
Correction: The isotope numbers of hydrogen (or any element for that matter) are the total number of protons+neutrons, not number of neutrons. So the most common isotope of hydrogen is just the proton, but sometimes you see Deuterium (with 1 neutron, mass 2) or Tritium (2 neutrons, mass 3)
Thanks for pointing that out. I've added a pinned comment to this video to correct that point for viewers. I appreciate that you and other commenters pointed it out. Seriously thank you!
Yoo im a big physics and computer science nerd, never really looked into biology and medicine. Thank you i really enjoyed this and i will def get out and learn more
4:36 actually that thing, what chemists call secondary bonding only possible because electron can be in superposition with itself. The whole Chemistry thing is a large scale result of Quantum mechanics. But I know this is RUclips. Only weird things get the "Quantum" label here.
Yup, nailed it. Me and my audience come mainly from an anatomy / physiology background, so that _quantum_ at 4:36 was a communication choice to try not to confuse the audience. Thanks for chiming in 🙌
I being a novice and have flunked in biology or only have passed barely to graduate and done poorly in Physics too high school so much so had to switch to Major in Maths and Computer Sciences for undergrad and grad school , Can say definitely Enjoyed your clip!
My work is selling enzymes to manufacturing industry or the "classic physic model" application you may say. Never thought enzyme could be rediscovered through quantum mechanics. Quantum biology is surely an interesting research...
Hydrogen usually has no neutron, but one proton, so that makes two nucleons, if that is what you mean. The next isotope of hydrogen has a neutron, and still of course only one proton, giving it two nucleons. This isotope is often called deuterium, D. The next one has two neutrons and is called Tritium because of the three nucleons
Carbon dioxide doesn't bind to Hemoglobin. Carbon monoxide does, with 200x higher affinity than oxygen. CO2 dissolves in the aqueous phase both inside and outside cells, converts to carbonate, etc.
Hey there, thanks for chiming in. I wouldn't want to mislead anyone, so here's my source that confirms that some CO2 does bind to hemoglobin. "Second, carbon dioxide can bind to plasma proteins or can enter red blood cells and bind to hemoglobin. This form transports about 10 percent of the carbon dioxide." opentextbc.ca/biology/chapter/20-4-transport-of-gases-in-human-bodily-fluids/
Sorta kinda. Little tip and trick, the ending -ose usually indicated a sugar, where -ase is usually an enzyme. Maltose would give sweetness to a food, although I don't know off the top of my head if bread is high in maltose. I thiiiiink it does?
I didn't follow you at 6:12 when you meant to say may be the enzymes were borrowing through the reaction? Didn't able to sum it up ! Plz explain further ?
I can't seem to find the link to part 3. I've found myself in a loop that sends me from part 1 to part 2, then back to part 1, etc. It's early in the morning, so part 3 is probably staring me in the face :D
I recall a quantum mechs question waaaay back in the early sixties - we had to calculate the probability of a one ton Buick tunneling thru a 1m high sinusoidal hill and appearing on the other side..😂😂
Depends on the protein. Usually you can search for the normative value for with and without enzymes. That's how I found the carbonic anhydrase values in this video!
Can I ask something? So we get to the conclusion that we have quantum tunneling at low temperatures but its not the driving force at higher temperature? I don't get the point of dinosaur tissue example. Why its tissue didn't disintegrate ? It still could disintegrate at higher temperature just as other stuff does! Why in that special case it didn't happen!
One more thing, the Klinmann experiment was done at very low temperature right ? Because at the high temperature the other effect will highly supersede over quantum effects?
Correct. It was a blunder on my part that really showed my incompetence with basic chemistry. I've pinned correction comments and added a card in the video to hopefully clarify the mistake. Thanks for chiming in
Well, this model sounds much more feasibly for extremophiles organism, specially those ones who survive at freezing temperatures. I wonder if they followed that line of research 🤔
Ok I was following you just fine up until 10:03 "Protium was catalyzed so much faster than the heavier isotopes that... it was acting more like a wave than a particle" Why do heavier isotopes catalyzing a lot slower than the lighter one mean that it's a wave? As an average layman, this came out of nowhere... sendhelp pls
I'm not a physics expert, but my understanding is that acting like a wave doesn't mean being one. If I remember correctly, light acts like both a particle and a wave in a way that is unconventional. So if the faster isotope is acting like a wave, it must be very fast. Please someone correct any misunderstanding, I'm not sure I am correct.
As a physics student I answer this, the tunneling probability is inversely proportional to mass. A heavy particle is much less likely to cross a barrier than a small particle. You can check the tunneling expression to ascertain that. Its a purely quantum effect.
8:45 hydrogen atoms usually DON'T have a neutron. One proton with one neutron is a nucleus of deuterium, a hydrogen isotope. Edit: oh sorry, someone else already corrected that, and in more detail.
Thanks for chiming in regardless. I'd rather viewers get correct information than anything, so I'm glad people are correcting me. Out of curiosity, I added correction cards in the upper right hand corner at that part -- did it show up for you?
I prefer Pilot Wave theory. I think the solid wall analogy doesn't work that well considering atoms and everything is mostly vacuum aside from the particles so it's never actually 0% chance of passing "through" another atom.
It feels a bit weird to hear people surprised by the tunnel effect at room tempertur. Since tunnel diodes are known in electrical engineering since the 1960s showing effects that can only be explaning by the tunneling effect taking place at room temperature.
Time-timing sync-duration that we look, listen, hear and see how it operates, is superposition Totality, and talking about quantization affects is half-truth superficiality inside-outside holographic positioning presence effects, nodal-vibrational Nomenclature is everything in Actuality, in the quantization Principle that defines bio-logical existence in Absolute zero-infinity axial-tangential orthogonality, Actuality. To clean up the curriculum is not particularly difficult, but it is very time consuming because Nomenclatures are Mathemagical Thought Experimentalist's practical Intuition confirmation of conformity to Form following Function.
Haha, I watch the other person he collaborated with a lot, that's Up and Atom's animation, and I just saw her say that the saladfinger is one of her big inspirations for her animation style. She explains quantum physics with that animation... It's great!
@@aaroncurtis8545 I came here through her Channel ;) subbed to her channel maybe a year ago?!? But i can't remember being reminded of David Firth's Stuff while watching her videos :D
@@DIYdiacsnFarmstead ohh... Very cool. I only know of salad fingers because she said in her live stream it was the biggest influence on her animation style. Anyways, you have good taste in RUclipsrs... ✌
@@aaroncurtis8545 haha, thanks! I remember saladfinger and all the other weired but cool stuff from david firth from about 10 years ago. Not quite sure what his new stuff is like or if he even does sth... You should check it out if you haven't already! Cheers :)
I am pretty excited about this channel. There are a zillion well-done physics channels out there that I consume every video veraciously. I've recently become seriously interested in biology but most of the videos covering biology tend to be more in the vein of a high school biology course, more worried about vocabulary than concepts. In Jade's video you discussed the excitons, and pardon the pun, but that really excite-onned- me. That is the sort of stuff I am just dying to learn about, the details that make the stuff we learned in school work. For example, I am dying for an understanding of exactly what is happening in the electron transport chain in the generation of ATP. Every explanation says the same thing "a high energy electron moves through the chain." What...does...that...mean! Anywho, this comment is long enough. I "mashed that subscribe button," looking forward to seeing what else you have.
That pun is appreciated. You'll see more anatomy and physiology content on this channel. Less strict biology or physics and more of the story behind the science. Glad to have you here!
Check you facts about the isotopes of hydrogen. There are three naturally occurring hydrogen isotopes. Normal hydrogen has no neutrons, deuterium has one neutron, and tritium has two neutrons.
Maybe you don't always need quantum mechanics to explain biology - after all, they are like 3 emergence levels removed - but that doesn't mean there's no connection, or even potential for new explanations
I see others have pointed out this major goof: Ordinary hydrogen (protium) has one proton and NO neutrons. Deuterium has one proton and ONE neutron. Tritium has one proton and TWO neutrons. Tsk tsk!
You glossed too quickly over why Quantum effects may not have played a role in the dinosaur collagen case. "Life On the Edge" makes the case for it, which you dismiss in the last few seconds. I think I heard you notice that the evidence for tunneling crossed over with classical explanations at 30C, but then you hand-waved away the evidence of ~65 million years of no collagen breakdown. What are the arguments pro/con for quantum effects in collagenase? Kind of a tease to post a video on Quantum Biology in enzymes, then present it, and quickly conclude that this was possibly not an example of it. Maybe you need a follow-up video. It would be great to get Khalil or other authors of Quantum Biology: Life on the Edge to participate.
"...spot enzymes because they end in _ase_ ..." yep just like RuBisCO! Okay I guess technically the full name does end in ase but nobody uses the full name when talking about rubisco so my point remains.
A few pieces of well-meant and hopefully constructive criticism: Try to make your images fit your script a bit more. E.g 1: At 4:04 you say that the enzyme and the substrate both have to change their shape a bit to fit into each other. But what you are showing is the opposite: the outdated puzzle piece / lock&key model. E.g 2: I found the images at 10:15 and 10:22 distracting. My brain wanted to find out what this is and stopped listening to what you said. I had to watch that part multiple times before I could concentrate on what you are saying. They are beautiful and fascinating pictures, but that's exactly the problem. The sound effect at 6:07 is way too loud compared to the volume of your speech. 9:24 is much better! Finally, I just wanted to mention that I really appreciate the SI units! :-) Thank you for making this video!
I came to your channel from Jade's and I was bored to death. You have good info, but somehow the presentation started to drone on after a while and I found my mind wandering. I don't mean this as a criticism but just feedback. I'm sure you are much more engaging in front of students.
Not scared, just at a loss trying to explain this math in a concise way. Here's the 1989 Klinman article if you want to check it out www.researchgate.net/profile/Christopher_Murray3/publication/224954062_Hydrogen_Tunneling_in_Enzyme_Reactions/links/0fcfd4fb2ca8d12265000000/Hydrogen-Tunneling-in-Enzyme-Reactions.pdf
For vital chemical processes to occur in the body, like dna replication, enzymes were needed to overcome the activation energy of those reactions and also bring molecules into the correct 3D configuration. These enzymes are highly complex protein quaternary entities, which are encoded in DNA. How can DNA evolve without the simultaneous evolution of enzymes it needs to function? It can’t, it’s called a causal loop. It can only be designed by an Intelligent Designer.
Small mistake:
Usually hydrogen is just a proton (no neutrons), but deuterium (1 proton and 1 neutron) and tritium (1 proton and 2 neutrons) also exist. I believe there was a mix up between mass number and number of neutrons
@@VijayshankerSingh Nah a pinned comment / correction at the top of description is fine. Lose any momentum by re-uploading.
Yeah, I was about to comment the same thing
Thanks for pointing that out. You're totally right and I don't know how that simple mistake made it past my editing. The conclusion of the Klinman experiment still stands: heavier isotopes react much more slowly than expected, so they must take advantage of tunneling. Thanks again for the correction!
@@Corporis But then you said it can be explained by classical mechanics.
Came to mention about the same fact
Woohoo!
Woo! Pat Kelly x Up and Atom = dream team 🙌🏻
@@VijayshankerSingh you're probably new to youtube
@vijayshanker singh Thanks for pointing it out. I've pinned a comment about the isotope point to avoid misleading anyone. Thanks for the feedback
Your videos are looking more and more incredible. This is insane. And this collab is the stuff of which dreams are made! QUANTUUUUUUUUUM
Watching video with left hand while eating right handed Apple ?
Medlife Crisis agreed!
@@TommoCarroll aha hello Tom. There's a definite Aspectish aspect to these little animations.
Thanks a bunch friend!! I think i'm finally setting into a style I like and can replicate. I'm happy to get back to the more macro anatomy and phys though, this quantum stuff is well past my comfort zone
Medlife Crisis well I’m stoked to know that aspectish is officially a verb haha. But yeah it’s awesome to see Pat’s style (and skills!) developing and I loved this look and feel for this episode!
What little I know about enzymes reminds me of my childhood. My mom once told me meat was so difficult to chew because my saliva lacked the enzymes to break it down into a swallowable form. I later found out it was because everything was cooked well done and tough as nails.
hahah! I've never heard that one before
I mean she’s not wrong. I’m pretty sure only your stomach and intestines are able to produce enzymes that break down proteins (they’re called peptidases) Saliva contains mostly amylase (sugar breaking enzymes) and lipases (fat breaking enzymes)
Here from Up and Atom. Always cool to find new channels like this. You got yourself another subscriber!
Same
Thank you so much, I appreciate it 🙌
Same to you. Welcome to the channel
I am also here from Up and Atom. Very happy that you took up the topic of quantum biology. I am a biologist, also interested in physics. I read the quantum biology book by al-Khalili & McFadden last year and became completely fascinated. Hope the discussion will continue. I like Up and Atom and have seen many episodes there, so now I found this channel and have subscribed.
Correction: The isotope numbers of hydrogen (or any element for that matter) are the total number of protons+neutrons, not number of neutrons.
So the most common isotope of hydrogen is just the proton, but sometimes you see Deuterium (with 1 neutron, mass 2) or Tritium (2 neutrons, mass 3)
Thanks for pointing that out. I've added a pinned comment to this video to correct that point for viewers. I appreciate that you and other commenters pointed it out. Seriously thank you!
I'm a high school student, and the way you explained at 3:10, you got yourself a new sub🙂
Much appreciated, welcome to the channel!
Side note, physiology is predictable when you get some etymology into your study!
Just remember that there are some exceptions to the ase naming scheme due to abbreviations (ie rubisco).
Yoo im a big physics and computer science nerd, never really looked into biology and medicine. Thank you i really enjoyed this and i will def get out and learn more
4:36 actually that thing, what chemists call secondary bonding only possible because electron can be in superposition with itself. The whole Chemistry thing is a large scale result of Quantum mechanics.
But I know this is RUclips. Only weird things get the "Quantum" label here.
Yup, nailed it. Me and my audience come mainly from an anatomy / physiology background, so that _quantum_ at 4:36 was a communication choice to try not to confuse the audience. Thanks for chiming in 🙌
This was dooooope dude
😊🙌😊
You’re going to get so far, we needed sb like you!
Great video! I love your stuff!
Much appreciated, thanks for the kind words
Keep up the collaborations - new sub from watching the up & atom vid! I love learning new things like this.
Thank you! I've got a collab with a world history channel coming soon!
Nice elaboration.
Thank you
if the wave has total internal reflection from the wall it will constructively interfere and double the height thus able to scale the wall.
I being a novice and have flunked in biology or only have passed barely to graduate and done poorly in Physics too high school so much so had to switch to Major in Maths and Computer Sciences for undergrad and grad school , Can say definitely Enjoyed your clip!
My work is selling enzymes to manufacturing industry or the "classic physic model" application you may say. Never thought enzyme could be rediscovered through quantum mechanics. Quantum biology is surely an interesting research...
Hydrogen usually has no neutron, but one proton, so that makes two nucleons, if that is what you mean. The next isotope of hydrogen has a neutron, and still of course only one proton, giving it two nucleons. This isotope is often called deuterium, D. The next one has two neutrons and is called Tritium because of the three nucleons
New to your channel. great stuff so far. You definitely present the material in an interesting manner... The being "hot" part sort of helps too...
Up and Atom made me come here and I'm grateful for it!
Welcome over! Thanks for saying hi
Amazing content!
Carbon dioxide doesn't bind to Hemoglobin. Carbon monoxide does, with 200x higher affinity than oxygen. CO2 dissolves in the aqueous phase both inside and outside cells, converts to carbonate, etc.
Hey there, thanks for chiming in. I wouldn't want to mislead anyone, so here's my source that confirms that some CO2 does bind to hemoglobin.
"Second, carbon dioxide can bind to plasma proteins or can enter red blood cells and bind to hemoglobin. This form transports about 10 percent of the carbon dioxide."
opentextbc.ca/biology/chapter/20-4-transport-of-gases-in-human-bodily-fluids/
That cartoon with the wall was actually one of the best visual representations of wave particle duality I could understand.
Wonderful video, glad to be a new subscriber!
Thank you so much, I appreciate it 🙌
The animations are great though,makes my understanding much better.
Thank you! I get a lot of inspiration from a channel called Aspect Science. His animations are very, very good
Hey, let's hope this crossover brings more subs like me across! You deserve it man!
Much appreciated, thank you 😊
Just discovered your channel (via Jade) 👍🏻 thanks for making such complex stuff more understandable 👍🏻
Much appreciated, thank you 😊And thanks for all the social media follows, hasn't gone unnoticed
Thank you for the informative video! At minute 10:28, shouldn’t the publication year of the paper be 2013 instead of 2004?
Isn't maltase which makes bread taste sweet after chewing a little while? Especially for white bread.
Sorta kinda. Little tip and trick, the ending -ose usually indicated a sugar, where -ase is usually an enzyme. Maltose would give sweetness to a food, although I don't know off the top of my head if bread is high in maltose. I thiiiiink it does?
I didn't follow you at 6:12 when you meant to say may be the enzymes were borrowing through the reaction? Didn't able to sum it up ! Plz explain further ?
I can't seem to find the link to part 3. I've found myself in a loop that sends me from part 1 to part 2, then back to part 1, etc. It's early in the morning, so part 3 is probably staring me in the face :D
I dont think it has been uploaded yet.
Same error here, just realized that this video was released today. :facepalm: this is how partial season releases for series feel like
Confirmed, it's coming next week
@@Corporis Thanks for the info.
Wave/particle best expressed by field.
I recall a quantum mechs question waaaay back in the early sixties - we had to calculate the probability of a one ton Buick tunneling thru a 1m high sinusoidal hill and appearing on the other side..😂😂
Sounds like that probability is not very high!
What would the rate of protein synthesis be without enzymes?
Depends on the protein. Usually you can search for the normative value for with and without enzymes. That's how I found the carbonic anhydrase values in this video!
I subscribed to your channel😁
Much appreciated, thank you 😊
It's interesting to me that features of quantum mechanics seem similar to temporal aliasing bugs in software.
Can I ask something? So we get to the conclusion that we have quantum tunneling at low temperatures but its not the driving force at higher temperature?
I don't get the point of dinosaur tissue example. Why its tissue didn't disintegrate ? It still could disintegrate at higher temperature just as other stuff does! Why in that special case it didn't happen!
One more thing, the Klinmann experiment was done at very low temperature right ? Because at the high temperature the other effect will highly supersede over quantum effects?
8:40 What? Hydrogen atoms usually have zero neutrons. Zero neutrons is the most common isotope of hydrogen.
Correct. It was a blunder on my part that really showed my incompetence with basic chemistry. I've pinned correction comments and added a card in the video to hopefully clarify the mistake. Thanks for chiming in
Do you know how the cytoplasm didn't freeze at temperatures below 0C?
Good question. I don't know how exactly, but I was also surprised that the medium used in the 1966 experiment had such a low freezing point.
I think metamorphosis of frog would have been best example to illustrate quantum tunnelling.
But this is amazing too love it.
How so? Just curious:)
So QT has no relevance to enzymes and subsequent reactions happening in the human body?
8:43 Ah yes, hydrogen with three neutrons, Quadritium!
It was a silly mistake that I wish I caught before publishing. Alas, here we are
Well, this model sounds much more feasibly for extremophiles organism, specially those ones who survive at freezing temperatures. I wonder if they followed that line of research 🤔
Life finds a way!!
Ok I was following you just fine up until 10:03
"Protium was catalyzed so much faster than the heavier isotopes that... it was acting more like a wave than a particle"
Why do heavier isotopes catalyzing a lot slower than the lighter one mean that it's a wave?
As an average layman, this came out of nowhere... sendhelp pls
I'm not a physics expert, but my understanding is that acting like a wave doesn't mean being one. If I remember correctly, light acts like both a particle and a wave in a way that is unconventional. So if the faster isotope is acting like a wave, it must be very fast. Please someone correct any misunderstanding, I'm not sure I am correct.
As a physics student I answer this, the tunneling probability is inversely proportional to mass. A heavy particle is much less likely to cross a barrier than a small particle. You can check the tunneling expression to ascertain that. Its a purely quantum effect.
I am confused with the conclusion of the video, if the quantum effects are negligible at room temperature then why are we even considering it
I call that there’s a real life equivalent of Minecraft’s ‘South-East’ rule and it’s playing part in those enzyme structures.
I think carbonic anhydrase hydrates 1.000.000 CO2 molecules per second
I found a few different sources, ranging from 10^6 to 10^4 so I split the difference for safety. Thanks for pointing it out!
8:45 hydrogen atoms usually DON'T have a neutron.
One proton with one neutron is a nucleus of deuterium, a hydrogen isotope.
Edit: oh sorry, someone else already corrected that, and in more detail.
Thanks for chiming in regardless. I'd rather viewers get correct information than anything, so I'm glad people are correcting me. Out of curiosity, I added correction cards in the upper right hand corner at that part -- did it show up for you?
Nice video. Put a pinned comment regarding hydrogen.
Done. I really appreciate all yall calling me out on it. It was a rookie mistake on my part but I'm glad you caught it
I prefer Pilot Wave theory. I think the solid wall analogy doesn't work that well considering atoms and everything is mostly vacuum aside from the particles so it's never actually 0% chance of passing "through" another atom.
Yep, that's above my understanding for sure.
6:59 Oh! You are sweating so drench. Still keeping up a good show in smiley face. Kudos! (But seriously do something with the air conditioning!)
It feels a bit weird to hear people surprised by the tunnel effect at room tempertur. Since tunnel diodes are known in electrical engineering since the 1960s showing effects that can only be explaning by the tunneling effect taking place at room temperature.
It's all fascinating to my biology brain!
Time-timing sync-duration that we look, listen, hear and see how it operates, is superposition Totality, and talking about quantization affects is half-truth superficiality inside-outside holographic positioning presence effects, nodal-vibrational Nomenclature is everything in Actuality, in the quantization Principle that defines bio-logical existence in Absolute zero-infinity axial-tangential orthogonality, Actuality.
To clean up the curriculum is not particularly difficult, but it is very time consuming because Nomenclatures are Mathemagical Thought Experimentalist's practical Intuition confirmation of conformity to Form following Function.
6:55 Saladfinger, is that you?
Haha, I watch the other person he collaborated with a lot, that's Up and Atom's animation, and I just saw her say that the saladfinger is one of her big inspirations for her animation style. She explains quantum physics with that animation... It's great!
@@aaroncurtis8545 I came here through her Channel ;) subbed to her channel maybe a year ago?!? But i can't remember being reminded of David Firth's Stuff while watching her videos :D
@@DIYdiacsnFarmstead ohh... Very cool. I only know of salad fingers because she said in her live stream it was the biggest influence on her animation style. Anyways, you have good taste in RUclipsrs... ✌
@@aaroncurtis8545 haha, thanks! I remember saladfinger and all the other weired but cool stuff from david firth from about 10 years ago. Not quite sure what his new stuff is like or if he even does sth...
You should check it out if you haven't already! Cheers :)
Well I just subscribed to your channel after coming here from Jade's.
Much appreciated, welcome!
Plot Twist...It actually goes around the wall. No Tunnels Needed
I am pretty excited about this channel. There are a zillion well-done physics channels out there that I consume every video veraciously. I've recently become seriously interested in biology but most of the videos covering biology tend to be more in the vein of a high school biology course, more worried about vocabulary than concepts.
In Jade's video you discussed the excitons, and pardon the pun, but that really excite-onned- me. That is the sort of stuff I am just dying to learn about, the details that make the stuff we learned in school work. For example, I am dying for an understanding of exactly what is happening in the electron transport chain in the generation of ATP. Every explanation says the same thing "a high energy electron moves through the chain." What...does...that...mean!
Anywho, this comment is long enough. I "mashed that subscribe button," looking forward to seeing what else you have.
That pun is appreciated. You'll see more anatomy and physiology content on this channel. Less strict biology or physics and more of the story behind the science. Glad to have you here!
the editing is so good djsvzjabxos
Thanks Izz. Took a long time on it. Hyped for our video!
Life is to quantum mechanics what your crush is to you: so hot that you lose coherence.
That's an A+ physics pickup line. 10 points
Time travelling dinosaurs! I knew it!
Linus Pauling looks like a mad scientist.
I feel like you have to be kind of a mad scientist to be on Pauling's level ;)
@@Corporis nice one👌
Back when this channel was filmed in the science lab
Sent by Jade. ;)
Replied by me. Welcome to the channel Michael 🙌
Perhaps the dinosaur is not as old as we think it is.
Check you facts about the isotopes of hydrogen. There are three naturally occurring hydrogen isotopes. Normal hydrogen has no neutrons, deuterium has one neutron, and tritium has two neutrons.
Thanks for pointing it out. A few people have, so I added the two cards on the video and pinned a few comments about it. I appreciate the feedback !
hey Mr. Kelly, its me Luis =)
Hey Luis, it's Mr Kelly. Hope you're doing well :)
I still cannot see how the tunneling helped the soft tissue of T rex to survive. Somebody please drop a comment.
“Dang, this is dope.” Ok, I’m way to old to know what that means - interpret for me someone!
It means it's cool or interesting.
Confirmed. Means cool or interesting in this context.
is it just me, but i always picture a proton being red.your whole isotope animation kind of threw me)
Maybe you don't always need quantum mechanics to explain biology - after all, they are like 3 emergence levels removed - but that doesn't mean there's no connection, or even potential for new explanations
Nicolai Veliki sounds like we came to the same conclusion
@@Corporis I did come to this conclusion after watching your video, so you get a lot of credit for that.
Also a new subscriber
@@nicolaiveliki1409 Awesome dude, welcome
6:06 PSHHHPSHHHH
[CYXXYC] definitely not a subtle sound effect, but you sure noticed the paper title!
I see others have pointed out this major goof: Ordinary hydrogen (protium) has one proton and NO neutrons. Deuterium has one proton and ONE neutron. Tritium has one proton and TWO neutrons. Tsk tsk!
That mistake really was the blunder that keeps on giving! Thanks for making it through regardless!
You glossed too quickly over why Quantum effects may not have played a role in the dinosaur collagen case. "Life On the Edge" makes the case for it, which you dismiss in the last few seconds. I think I heard you notice that the evidence for tunneling crossed over with classical explanations at 30C, but then you hand-waved away the evidence of ~65 million years of no collagen breakdown. What are the arguments pro/con for quantum effects in collagenase? Kind of a tease to post a video on Quantum Biology in enzymes, then present it, and quickly conclude that this was possibly not an example of it. Maybe you need a follow-up video. It would be great to get Khalil or other authors of Quantum Biology: Life on the Edge to participate.
Excuse me. I want to be confused with the math.
Link is in the description for the 1989 Klinman paper. Good luck and godspeed.
And this is set all the young earth creationists off 😂😂
Bring emm on
7
Am I the only one who is more confused by this.... His the wall but somehow, like a ghost, goes thru❓
"...spot enzymes because they end in _ase_ ..." yep just like RuBisCO!
Okay I guess technically the full name does end in ase but nobody uses the full name when talking about rubisco so my point remains.
10 17
10 21
Watching this video felt like watching something from vox
That's exactly the vibe I"m going for. Thanks for the compliment!
*waves* Herroooo
4:35 how dare you put quantum before a joke
🤘🤘🤘
✊🙌
A few pieces of well-meant and hopefully constructive criticism:
Try to make your images fit your script a bit more.
E.g 1:
At 4:04 you say that the enzyme and the substrate both have to change their shape a bit to fit into each other. But what you are showing is the opposite: the outdated puzzle piece / lock&key model.
E.g 2:
I found the images at 10:15 and 10:22 distracting. My brain wanted to find out what this is and stopped listening to what you said. I had to watch that part multiple times before I could concentrate on what you are saying. They are beautiful and fascinating pictures, but that's exactly the problem.
The sound effect at 6:07 is way too loud compared to the volume of your speech. 9:24 is much better!
Finally, I just wanted to mention that I really appreciate the SI units! :-)
Thank you for making this video!
Thanks for the feedback, it's much appreciated.
WHAT.
The host is 10/10 DILF material.
Yea
*HYDROGEN NATURALLY HAVE ONE NEUTRON*
Abomination of chemistry
Please see the pinned comment for my correction. I hope the video was still useful
I came to your channel from Jade's and I was bored to death. You have good info, but somehow the presentation started to drone on after a while and I found my mind wandering. I don't mean this as a criticism but just feedback. I'm sure you are much more engaging in front of students.
Different strokes for different folks. Thanks for watching regardless
What a smoke show.
We’ll see. Like I said in the video, there’s some evidence to support the quantum biology model but we’ll see where the research goes
"I'm not trying to confuse you by showing calculations"
Sounds like you're too scared to present an in-depth view into the actual science.
Not scared, just at a loss trying to explain this math in a concise way. Here's the 1989 Klinman article if you want to check it out www.researchgate.net/profile/Christopher_Murray3/publication/224954062_Hydrogen_Tunneling_in_Enzyme_Reactions/links/0fcfd4fb2ca8d12265000000/Hydrogen-Tunneling-in-Enzyme-Reactions.pdf
For vital chemical processes to occur in the body, like dna replication, enzymes were needed to overcome the activation energy of those reactions and also bring molecules into the correct 3D configuration. These enzymes are highly complex protein quaternary entities, which are encoded in DNA. How can DNA evolve without the simultaneous evolution of enzymes it needs to function? It can’t, it’s called a causal loop. It can only be designed by an Intelligent Designer.
The presence of soft tissue in dinosaur bones means they’re not millions of years old.
the more we know, the more we realise that we don't know shit
That's the mark of a good scholar right there 🙌