Diagnosis, Treatment and Safety of Growth Hormone Therapy in Adults

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  • Опубликовано: 27 июл 2024
  • Adult growth hormone (GH) deficiency is a syndrome characterized by abnormal body composition of decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of life, unfavorable alterations in glucose and lipid profiles and markers of cardiovascular risk, decrease in bone mineral density, and increased mortality. Unlike in children where height velocity is a clinical marker, given the lack of specific clinical markers in adults, biochemical confirmation of the diagnosis using appropriate GH stimulation test/s is essential. When dosed appropriately using serum insulin-like growth factor-I (IGF-I) as a serum biomarker, GH replacement therapy is usually well tolerated, with a low incidence of side effects, and improves many of the alterations observed in adult GH deficiency, although beneficial effects on mortality and cardiovascular events, however, remain to be conclusively demonstrated. The potential of GH to act as a mitogen has raised some concerns over the possibility of increased de novo tumors or hypothalamic/pituitary tumor recurrence in adult treated with long-term GH. Though studies of adults who received GH replacement therapy in childhood have produced conflicting reports in this area, there have been several long-term surveillance studies of adults on GH replacement therapy that have provided reassuring data by demonstrating no increase in cancer risk or mortality.

Комментарии • 15

  • @Fedko3037
    @Fedko3037 8 лет назад +2

    Great presentation, especially liked the specific considerations in testing for people with concurrent disease.

  • @libraryfiles4470
    @libraryfiles4470 4 года назад +3

    Why not take IGF-1 instead of HGH?

  • @channghiem5012
    @channghiem5012 3 года назад

    he speak sooo slow it hurts meto listen almost. that you for your contribution

  • @BRAVOOcity-vlog-music
    @BRAVOOcity-vlog-music 4 года назад

    hey guys , i wanted to thank you for the presentations you making on this channel !
    my question : wel i am 37 yo ! i am 5,5 tall .... i want to reach the 6,1 tall .
    when asking orthopeidist about this .... they mentioned it's possible "via the limb lengthening" but they cant do much on the skull and the vertebraes "
    SO , can this growth hormone help here ???? THANK YOU

  • @paulao7022
    @paulao7022 4 года назад +1

    Can taking Amino Acids, help boost the active, growth hormone in our bodies??

    • @libraryfiles4470
      @libraryfiles4470 4 года назад +1

      Arginine possibly

    • @ShellyCline
      @ShellyCline Год назад

      Not if your pituitary gland just isn't making the hormone.

  • @chaltutusee8301
    @chaltutusee8301 7 лет назад

    from where I buy HGH please can you halp me anther I am 32 years old is work for me and I short I wants Taller ok please geff to me answer

    • @roberthunter9805
      @roberthunter9805 7 лет назад

      bho labs

    • @roberthunter9805
      @roberthunter9805 7 лет назад

      you stop growing at 21 years old max as growth plates close at this age max some people are younger I am only 5 foot 7 and a half would have liked to have been over 6 feet nothing that can be done once growth plates close, If we knew what we know now when we were a teenager

    • @libraryfiles4470
      @libraryfiles4470 4 года назад

      You short
      You stay short
      God say so

    • @BRAVOOcity-vlog-music
      @BRAVOOcity-vlog-music 3 года назад

      @@libraryfiles4470 you