Making Stretchable Hydrogel | Synthesis poly(Acrylamide)/Alginate wound dressing Hydrogel
HTML-код
- Опубликовано: 24 янв 2021
- stretchable hydrogel electronics and devices, stretchable hydrogel sheet, stretchable and transparent hydrogel, highly stretchable hydrogel ..!!! Most hydrogels have relatively low tensile strength and low elasticity, which limits their application capacity in the biomedical field. In order to improve the mechanical properties of hydrogels, highly stretchable and tough hydrogels have been invented recently. If a sensor is to be wearable, it should generally be highly stretchable to ensure comfort for the wearer. The biocompatible hydrogel has the ability to strecht up to a strain of 5000%. Highly stretchable and tough hydrogels can be implemented in multiple diferent fields, such as mechanical sensors. Properties important to making a good mechanical sensor, such as gauge factor, self-healing, and having strong mechanical properties, can be seen within these hydrogels. Highly stretchable and tough hydrogels, with great adhesion strength and healing times, can be utilized for wound healing. The mechanical properties of tough, highly stretchable hydrogels can be used for drug delivery.
Наука
well done , your video help me a lot
Thank you! The video is great!
Thank u.
That was an informative video. I have a question if u dont mind. Its possible to surface functionalized this hydrogel after syntheses with Anti-oxidant? I already saw the other video of ferrogel as well that you magnetite the hydrogel with Fe3O4. Thank you in advance for your reply.
Can you make video on how to dissolve Sodium polyacrylate or other natural or chemically C L hydrogel to reform its shape for making pad of it ?
I'm working on hydrogel for wound healing can we use pcc catalyst for oxidation?
Except freeze/thawing process how can I make hydrogel dry
Nice video, it will be very helpful for me and if it is possible can you please share me the chemical list of companies you purchased
Can we convert a medicated oil to a hydrogel and use for wound healing
Can I make hydocolloid gel sheet only from cmc and polyisobutylene
I'mThai ,so I can not understand in English clearly .But I interest in this jel .Can you list the ingradians all again please.😊
May I know the ingredients in detail?
I want to use it to make gel pads for the family. Realy thanks.
Can this hi
old weight? If not what could you add to it so it does
How to store this? And what is the shelf life of this hydrogel
Any side effects like blood clots ?
I just have a question about making leather from the cactus plant and what are the raw materials to make leather, and I know one of the materials used is polymer, and I hope someone can help about making vegan leathers.
Have you explored the rheological properties of this hydrogel yet? Does it exhibit shear thinning properties with shear stress?
Their rheological properties can be adjustable using Ca ions.
Love your videos. Red colourText is hard to read…
Link for its paper?
Hello, it was interesting to see this video so first thank you. I was wondering, could we use this type of hydrogel as a protection for screen like an hydrogel screen film, and is this hydrogel a chemical hydrogel ? Thank you in advance for your answers.
Thank you for your nice wishes. These can not bu use for protection the scree, these can be use for biomedical applications such as wound healing materials.
this is innovation
can you please let me know why you have used those particular chemicals? what was the need and what properties do they impart in hydrogel? it will be of great help.
Sodium alginate improve the mechanic properties.
it's very helpful for my disertation eksperimen
i would like to make lignin based hydrogel for heavy metal adsorben. How about lignin, can the hydrogel formula in your video combine with lignin?
Yes of course
Informative video,, I am also working on Chitosan based temperature and pH sensitive hydrogel,, i am using CS, NIPAAM, Amps, gultaraldehyde as a crosslinker, and APS as initiator, but my gel is becoming hard he brittle, it hasn't show any elasticity, can You please make a video on Chitosan based hydrogel ASAP,, thank you
Thank you. I hope. You can use glycerin.
Thank you for a great video. Have you published your that you could share?
Thank you. Not yet.
Hi, thanks for the video. I thought you would add also calcium chloride or calcium sulfate in order to crosslink the alginate as well and make a double network. Am I wrong? how does the presence or absence of an alginate crosslinker affect the properties of the gel? Thanks a lot in advance for your answer.
Yes u can use Ca ions for physically crosslinking the alginate segment. Not only calcium but also other polyvalent cations can be used for physical crosslinking. In this video, bentonite clay containing polyvalent cations is used in its structure. This clay made the hydrogel harder.
the physical crosslink as a sacrifice neetwork which can dissipate energy to improve the gel's toughness.
Hi... This was a really good and informative video... I wanted to ask if we could use this hydrogel to make skin patches ?
Of course you can use it. There are many articles in the literature related to this.
Wow this was nice and informative vdo! Can u plz tell me which polymer should we use for preparing gel like hydrogel ..which one gelatin or collagen or chitosan so that it should have some solud like consistency
Thank u, u can prepare their copolymer composite
Please send the link to the research article so I can download and understand more
In press process.
May I know how do you remove the remnant acrylamide monomer in the hydrogel? it is a neurotoxin, could it be put on the skin directly?
YeS, U are right.
Cihangir Bey iyi çalışmalar. Yara bakım ürünlerinde kullanılan hidrojellerle aynı mı sentezlediğiniz jel.?
Benzer, ama iyi saflaştırma yapmanız gerekir.
Hi! I'm unable to differentiate between hybrid hydrogels and synthetic hydrogels? I know that hybrid are a combination of natural and synthetic hydrogels, but how do I know which one is which by reading its name.
Yes u can.
Hi there,
Have you ever worked with chitosan to make hydrogels? In combination or alone
yes u can use chitosan. But it is not combine with alginate because their electronic properties. Chitosan is the cationic while alginate anionic.
Hi...Tnx for sharing your experience. How can we increase the adhesion of hydrogels?
U can increased using natural or sentetic polymer or additive. There is a many studies in the literature.
Hi, i hope you notice my comment. I am willing to do somtihng similer to your work, but I will be useing natural-polymer instade of poly(Acrylamide). Could you help me to find sutable polymer or how to find.
Thank you.
U can use alginate, chitosan, gelatin etc. U can crosslink by gluderaldehyde. Or u can use PVA. Its synthetic but biocompitable. U can crosslink it by gluderaldehyte or Freeze Thaw method.
hello super late but I wanna ask if this self heals? like if we cut it up into pieces would we still be able to merge them all together into 1 piece?
This is not but u can develope self healing worms using PVA
Hello, super nice video and very interesting. I am looking for something to bind electrical devices to hydrogel. Is there already a publication on this or can please tell me more about the method or where I can find literature? Thanks a lot for this!!!
Thanks. U can easily find many method in the literature. Basically, 2 gram Na-Alj, 14 gram Acrylamide and 0.05 gram of MBAAm radical polymerization.
@@polymerscope6881 thanks..
Hello, would it be possible to get a list of the things you've used in creating the hydrogel? It would be very helpful for our research experimentation, thank you!
There is a detailed explanation in the video. If you want to search 'acrylamide-based stretchable hydrogels', there are many studies in the literature.
How can I contact you
In vdo hydrogel is of film what can be added to make hard so that we can cut
U can add the multi cations contain clay such as Bentonite, it will do stronger
hi, can i know the material of the plate that used in the video ? Is plastic or styrofoam? Thank you
Popular known styrofoam plate.
Hi. Can you tell me how long do you need to wait before adding each material in this solution?
Just wait until you have a homogeneous mixture.
What about the homopolymers formed or any interacted monomers?
This PVA polymer composite, pure PVA, not contain other monmomer or polymer.
May I ask some questions,…Why u put bentonite to systhesis hydrogel & reason .
Betonite contains cations such multi charge cations like Ca cations, these cations crosslink the alginate chains which them makes stronger.
Can I start without Na Alginate?
i.e Dissolve acrylamide in water?
Than add MBA than APS than TMEDA
If u want to make a strach, u should us Na- Alginate.
The stirring part should be replaced by adding other components so that it can be injected into hip with artritis.
What is the role of each component in the polymerization process?
There is a detailed explanation in the video. If you want to search 'acrylamide-based stretchable hydrogels', there are many studies in the literature.
Hi! Do you know how to make home made hydrocolloid patches/bandages? Would love to learn if you could give me some tips!🙂
U can use PVA, starch, callogen, alginate, CMC. An u can use borax, glutaraldehyde or CaCl2 as physically crosslinker.
@@polymerscope6881 what about chitosan
?
Do you think that a hydrogel would work for a gel insole product for shoes? Could it work for the entire shoe?
Of course you can develop it for this purpose.
Sir how you prepared the NA ALGINATE SOLUTION
2 g / 100 ml water
Dear sir, how long did the cooling process take and what was the degree?
24 hours room temperature.
Can you please tell me which hydrogel should I prepare for the removal of drugs from wastewater?
You can prepare anionic hydrogels for cationic substances. So with AAm you can use AMPS, VSA, AAc. You can use chitosan polymer composite with AAm for adsorption of anionic substance.
Hi sir... I have a question?? Sir how to preserve this hydrogel for future experiment??
You can wrap it in aluminum foil and store it in the refrigerator.
How many grams of alginate and water were added in step 1?
2 g/ 100 ml
How to maintain the stability of hydrogel
keeping it moist and clean.
can you sugest any resurch paper ?
U can find many article in the literature.
Is it possible to start with polyacrylamide instead of its precursor?
NO. The crosslinker is incorporated into the polymer chains through radical addition to carbon-carbon double bonds. You need active radical sites. And you can't add initiator again to start the reaction of crosslinker with polyacrylamide because there're too few carbon-carbon double bonds in polyacrylamide.
Yes u can
Can I pour an antioxidant solution to make an antioxidant hydrogel?
Yes, for example, if u add essential oil, u can use in wound healing application such as burn therapy.
Is there any article relevant to this procedure??
In press process.
Hello sir, can i use collagen instead of Na-Alginate?
It can be but not flexible enough.
How to made polyvinylamine (PVAm) ?
please help!
There are detailed explanations in the literature.
@@polymerscope6881 Thank you very much!
sir please how much Bentonite have you added
It is not necessary to use bentonite. if you use it it gets tough.
Hii, I wish to know about two things
1. Adding 15 grams of acrylamide wouldn't be toxic?? I mean will the bandage still remain biocompatible?
2. How can we reduce the stickyness of hydrogel?
If your polymer fully pure, it is not toxic, or u can use other crosslinking method such as frezee thaw, gluteraldehyte., İf u use cacl2 or Bentonite clay, it will be stronger due to crosslinking alginate segments.
@@polymerscope6881 Hello, please could you explain again. If I used the exact same materials used in your video, will it be cytotoxic?
Sir if I want to add cellulose n encapsulated essential oil so when to add n how much will be the quantity?
U can try as 2 gram CMC/100 ml water.
Thank u sir
Hi! Would it be possible to know the specific rpm you used in stirring? Is it constant throughout the experiment? I would also like to know the duration of stirring if you don't mind. Thank you very much!
A mixing speed that satisfies you will suffice. The important thing is to ensure a homogeneous mixture.
I was very impressed by your video.
Why did you put in bentonite??
Thank you, bentonite is the good filler, I used it to increase the toughness of the material.
@@cihangirboztepe5918 Can Bentonite be replace with nanoparticles?
@@alakijafemi8047 Yes
@@cihangirboztepe5918 thank you. Is the hydrogel biodegradable?
@@alakijafemi8047 Yes
Can we change polyacrylamide with the natural ingredients?
Yes U can. Methacrylated alginate, gelatin etc. can be used. And u can UV photopolymerization crosslink method.
@@polymerscope6881 can I use cold water to make hydrogel? Cuz I want to make hydrojelly mask but I failed can u tell me where my mistake?
I make hydrojelly mask with ingredients :
1. sodium alginat
2. CaSO4.2H2O
3. Dimatecous earth
4. Sorbitol
5. Corn starch
I want to try with gelatin but gelatin have to use warm water to make it soluble so I still find another option.
HI thıs used tens pad
Yes but expensive for this purpose.
I am working on hydrogels . Using PVA POLYMER , natural starch extracted from mango karnel , glutaraldehyde as crosslinking agent
Good job.
Can we use something elsa instead of NA algnite
What type of tests and characterisations you done after the synthesis
Dear where are u from? I'm also working on hydrogel for wearable and stretchable devices in Korea
@@surajshinde682 i am working on wound based hydrogels
Is it possible for making strechable hydrogel using chitosan
Yes.
I tried , using glutaraldehyde,(crosslinker)glycerol(plasticizer) but didn't work out, why? Strechabillity is weak,
@@aswathyc9799 I suggest you review the sample articles on chitosan glutaraldehyde.
@@aswathyc9799 hello ,, your hydrogel from Chitosan has been prepared???
Sir can I use cellulose in this procedure??
Yes, u can use the carboxy methyl celluslose or their derivatives.
Thank u sir.kindly suggest me what should be the quantity of cellulose?n again with this can I add encapsulated essential oils also to prepare dermal patch.
What you did for drying ?
You can use glycerin and silica gel to prevent drying.
@@polymerscope6881 how much concentration of glycerine use
Sir i followed the same methodology with same chemicals concentration . And after 24 hr of drying My gel is hard
U dont use bentonite.
Yes i used Bentonite
Sir can you please send me your email so that i could ahare the pics of my gel
How you dried this hydrogel?
U can use oven.
@@polymerscope6881 thanks for reply. Can you tell how much time and temperature
@@alchemacademy5799 did u kept on oven!
Is this edible?
No.
How u removed Air bubbles
Vacuum.
@@polymerscope6881 thanks for reply I also used vacuum while I was doing my project work to remove air bubbles
@@nileshmarkad1518 then do not start the polymerization reaction immediately after the homogeneous mixture is achieved, wait for the air bubbles to rise to the solution surface, you can try the ultrasonic bath to speed up this process.
I dont care wot its made of,i dont want that in my body. Silicone was safe……until it hardened…..and wasnt safe!
LinkedIn profile plz