Thank you so much. Please Why does the inhibition of JAK3 and JAK1, along with major factors, help reduce rheumatoid inflammations compared to JAK2 and TYK2?
It is all about which cytokines/cytokines receptors use which JAK dimer. In each disease, serach for involved cytokines and then search for which Jaks are used to transmit the signal from these cytokines then use the specific jak inhibitors
جزاك الله خيرا
جزاك الله خير دكتور
جزاك الله خيرا د. احمد
جزاكم الله خير الجزاء يا رب
Thank you so much. Please Why does the inhibition of JAK3 and JAK1, along with major factors, help reduce rheumatoid inflammations compared to JAK2 and TYK2?
It is all about which cytokines/cytokines receptors use which JAK dimer. In each disease, serach for involved cytokines and then search for which Jaks are used to transmit the signal from these cytokines then use the specific jak inhibitors
جزاكم الله خيرا د احمد